Opacity family porins
Encyclopedia
Opacity family porins are a family of porin
s from pathogenic Neisseria
.
These bacteria possess a repertoire of phase-variable opacity proteins that mediate various pathogen/host cell interactions. These proteins are related to OmpA-like transmembrane domain
family.
Porin (protein)
Porins are beta barrel proteins that cross a cellular membrane and act as a pore through which molecules can diffuse. Unlike other membrane transport proteins, porins are large enough to allow passive diffusion, i.e., they act as channels that are specific to different types of molecules...
s from pathogenic Neisseria
Neisseria
The Neisseria is a large genus of commensal bacteria that colonize the mucosal surfaces of many animals. Of the 11 species that colonize humans, only two are pathogens. N. meningitidis and N. gonorrhoeae often cause asymptomatic infections, a commensal-like behavior...
.
These bacteria possess a repertoire of phase-variable opacity proteins that mediate various pathogen/host cell interactions. These proteins are related to OmpA-like transmembrane domain
OmpA-like transmembrane domain
OmpA-like transmembrane domain is an evolutionarily conserved domain of outer membrane proteins. This domain consists of an eight-stranded beta barrel. OmpA is the predominant cell surface antigen in enterobacteria found in about 100,000 copies per cell. The expression of OmpA is tightly regulated...
family.