Ohio Key is an island in the lower Florida Keys

Florida Keys

The Florida Keys are a coral archipelago in southeast United States. They begin at the southeastern tip of the Florida peninsula, about south of Miami, and extend in a gentle arc south-southwest and then westward to Key West, the westernmost of the inhabited islands, and on to the uninhabited Dry...

.

U.S. 1

U.S. Route 1 in Florida

U.S. Route 1 in Florida runs along the state's east coast from Key West to its crossing of the St. Marys River into Georgia north of Boulogne, and south of Folkston. US 1 was designated through Florida when the U.S. Highway System was established in 1926.US 1 runs in the state of Florida, and...

 (or the Overseas Highway

Overseas Highway

The Overseas Highway is a highway carrying U.S. Route 1 through the Florida Keys. Large parts of it were built on the former right-of-way of the Overseas Railroad, the Key West Extension of the Florida East Coast Railway. Completed in 1912, the Overseas Railroad was heavily damaged and partially...

) crosses the key at approximately mile marker 39, between Missouri Key

Missouri Key

Missouri Key is a small island in the lower Florida Keys.U.S. 1 crosses the key at approximately mile marker 39.5, between Ohio Key and Little Duck Key....

 and Bahia Honda Key

Bahia Honda Key

Bahia Honda , is an island in the lower Florida Keys.U.S...

.

It was once known as Little Duck Key, however the name Little Duck Key

Little Duck Key

Little Duck Key is a small island in the lower Florida Keys.U.S. 1 crosses the key at approximately mile marker 40, just west of the Seven Mile Bridge...

 is currently used for a very small island about a mile east that is the western terminus of the Seven Mile Bridge

Seven Mile Bridge

The Seven Mile Bridge is a famous bridge in the Florida Keys, in Monroe County, Florida, United States. It connects Knight's Key in the Middle Keys to Little Duck Key in the Lower Keys...

.

Today it is also known as Sunshine Key, after a camping resort located there.

The portion of the island south of US Route 1 is protected as the Ohio Key National Wildlife Refuge.