Ochratoxin
Encyclopedia
Ochratoxins are a group of mycotoxin
Mycotoxin
A mycotoxin is a toxic secondary metabolite produced by organisms of the fungus kingdom, commonly known as molds. The term ‘mycotoxin’ is usually reserved for the toxic chemical products produced by fungi that readily colonize crops...

s produced by some Aspergillus
Aspergillus
Aspergillus is a genus consisting of several hundred mold species found in various climates worldwide. Aspergillus was first catalogued in 1729 by the Italian priest and biologist Pier Antonio Micheli...

species and Penicillium
Penicillium
Penicillium is a genus of ascomycetous fungi of major importance in the natural environment as well as food and drug production. Members of the genus produce penicillin, a molecule that is used as an antibiotic, which kills or stops the growth of certain kinds of bacteria inside the body...

species including Aspergillus ochraceus and Penicillium viridicatum. Ochratoxin A
Ochratoxin A
Ochratoxin A, a toxin produced by Aspergillus ochraceus, Aspergillus carbonarius and Penicillium verrucosum, is one of the most abundant food-contaminating mycotoxins in the world. Human exposure occurs mainly through consumption of improperly stored food products, particularly contaminated grain...

 is the most prevalent and relevant fungal toxin of this group, while ochratoxins B and C are of lesser importance.

Ochratoxin A is known to occur in commodities such as cereals, coffee, dried fruit and red wine. It is considered a human carcinogen
Carcinogen
A carcinogen is any substance, radionuclide, or radiation that is an agent directly involved in causing cancer. This may be due to the ability to damage the genome or to the disruption of cellular metabolic processes...

and is of special interest as it can be accumulated in the meat of animals. Thus meat and meat products can be contaminated with this toxin. Exposure to ochratoxins through diet can have can acute toxicity to mammalian kidneys, and may be carcinogenic.

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