Neuroprotectin
Encyclopedia
Neuroprotectin D1 is a docosanoid
derived from the polyunsaturated fatty acid
(PUFA) docosahexaenoic acid
(DHA), which is a component of fish oil and the most important omega-3 PUFA. NPD1 exerts potent anti-inflammatory
and anti-apoptotic bioactivity at nanomolar concentrations in a variety of experimental models of brain and retinal diseases.
Neuroprotectins A and B are bicyclohexapeptides.
Docosanoid
In biochemistry, Docosanoids are signaling molecules made by oxygenation of twenty-two-carbon essential fatty acids, , especially Docosahexaenoic acid...
derived from the polyunsaturated fatty acid
Polyunsaturated fatty acid
Polyunsaturated fatty acids are fatty acids that contain more than one double bond in their backbone. This class includes many important compounds, such as essential fatty acids and those that give drying oils their characteristic property....
(PUFA) docosahexaenoic acid
Docosahexaenoic acid
Docosahexaenoic acid is an omega-3 fatty acid that is a primary structural component of the human brain and retina. In chemical structure, DHA is a carboxylic acid with a 22-carbon chain and six cis double bonds; the first double bond is located at the third carbon from the omega end...
(DHA), which is a component of fish oil and the most important omega-3 PUFA. NPD1 exerts potent anti-inflammatory
Anti-inflammatory
Anti-inflammatory refers to the property of a substance or treatment that reduces inflammation. Anti-inflammatory drugs make up about half of analgesics, remedying pain by reducing inflammation as opposed to opioids, which affect the central nervous system....
and anti-apoptotic bioactivity at nanomolar concentrations in a variety of experimental models of brain and retinal diseases.
Neuroprotectins A and B are bicyclohexapeptides.