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Nervous system



 
 
The nervous system is a network
Neural network

Traditionally, the term neural network had been used to refer to a network or circuit of neuron. The modern usage of the term often refers to artificial neural networks, which are composed of artificial neurons or nodes....
 of specialized cells that communicate information about an animal's surroundings and itself. It processes this information and causes reactions in other parts of the body. It is composed of neuron
Neuron

Neurons are responsive cell in the nervous system that process and transmit information by electrochemical Signal . They are the core components of the brain, the vertebrate spinal cord, the invertebrate ventral nerve cord, and the peripheral nerves....
s and other specialized cells called glia, that aid in the function of the neurons. The nervous system is divided broadly into two categories: the peripheral nervous system
Peripheral nervous system

The peripheral nervous system resides or extends outside the central nervous system , which consists of the brain and spinal cord. The main function of the PNS is to connect the CNS to the limbs and organs....
 and the central nervous system
Central nervous system

The central nervous system is the part of the nervous system that functions to coordinate the activity of all parts of the bodies of multicellular organisms....
. Neurons generate and conduct impulse
Impulse

In classical mechanics, an impulse is defined as the integral of a force with respect to time. When a force is applied to a rigid body it changes the momentum of that body....
s between and within the two systems. The peripheral nervous system is composed of sensory neurons and the neurons that connect them to the nerve cord
Nerve cord

Nerve cord may refer to the following structures:* in invertebrates, it refers to the ventral nerve cord, whereas* in chordates, it stands for the dorsal nerve cord....
, spinal cord
Spinal cord

The spinal cord is a long, thin, tubular bundle of neuron and glia that extends from the brain. The brain and spinal cord together make up the central nervous system....
 and brain
Brain

The brain is the center of the nervous system in all vertebrate, and most invertebrate, animals. Some primitive animals such as cnidarian and echinoderm have a decentralized nervous system without a brain, while sponges lack any nervous system at all....
, which make up the central nervous system
Central nervous system

The central nervous system is the part of the nervous system that functions to coordinate the activity of all parts of the bodies of multicellular organisms....
.






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Encyclopedia


The nervous system is a network
Neural network

Traditionally, the term neural network had been used to refer to a network or circuit of neuron. The modern usage of the term often refers to artificial neural networks, which are composed of artificial neurons or nodes....
 of specialized cells that communicate information about an animal's surroundings and itself. It processes this information and causes reactions in other parts of the body. It is composed of neuron
Neuron

Neurons are responsive cell in the nervous system that process and transmit information by electrochemical Signal . They are the core components of the brain, the vertebrate spinal cord, the invertebrate ventral nerve cord, and the peripheral nerves....
s and other specialized cells called glia, that aid in the function of the neurons. The nervous system is divided broadly into two categories: the peripheral nervous system
Peripheral nervous system

The peripheral nervous system resides or extends outside the central nervous system , which consists of the brain and spinal cord. The main function of the PNS is to connect the CNS to the limbs and organs....
 and the central nervous system
Central nervous system

The central nervous system is the part of the nervous system that functions to coordinate the activity of all parts of the bodies of multicellular organisms....
. Neurons generate and conduct impulse
Impulse

In classical mechanics, an impulse is defined as the integral of a force with respect to time. When a force is applied to a rigid body it changes the momentum of that body....
s between and within the two systems. The peripheral nervous system is composed of sensory neurons and the neurons that connect them to the nerve cord
Nerve cord

Nerve cord may refer to the following structures:* in invertebrates, it refers to the ventral nerve cord, whereas* in chordates, it stands for the dorsal nerve cord....
, spinal cord
Spinal cord

The spinal cord is a long, thin, tubular bundle of neuron and glia that extends from the brain. The brain and spinal cord together make up the central nervous system....
 and brain
Brain

The brain is the center of the nervous system in all vertebrate, and most invertebrate, animals. Some primitive animals such as cnidarian and echinoderm have a decentralized nervous system without a brain, while sponges lack any nervous system at all....
, which make up the central nervous system
Central nervous system

The central nervous system is the part of the nervous system that functions to coordinate the activity of all parts of the bodies of multicellular organisms....
. In response to stimuli, sensory neurons generate and propagate signals to the central nervous system
Central nervous system

The central nervous system is the part of the nervous system that functions to coordinate the activity of all parts of the bodies of multicellular organisms....
 which then processes and conducts signals back to the muscle
MUSCLE

MUSCLE is public domain, multiple sequence alignment software for protein and nucleotide sequences.MUSCLE is integrated into UGENE bioinformatics tool as a plugin....
s and gland
Gland

A gland is an Organ in an animal's body that synthesizes a substance for release such as hormones or breast milk, often into the bloodstream or into cavities inside the body or its outer surface ....
s. The neurons of the nervous systems of animals are interconnected in complex arrangements and use electrochemical signals and neurotransmitter
Neurotransmitter

Neurotransmitters are chemistry which relay, amplify and modulate signals between a neuron and another cell . Neurotransmitters are packaged into vesicles that cluster beneath the membrane on the presynaptic side of a synapse, and are released into the synaptic cleft, where they bind to receptors in the membrane on the postsynaptic side of...
s to transmit impulses from one neuron to the next. The interaction of the different neurons form neural circuits that regulate an organism's perception of the world and what is going on with its body, thus regulating its behavior. Nervous systems are found in many multicellular animal
Animal

Animals are a major group of multicellular, eukaryotic organisms of the Kingdom Animalia or Metazoa. Their body plan eventually becomes fixed as they develop, although some undergo a process of metamorphosis later on in their life....
s but differ greatly in complexity between species.

Nervous system in humans


The human nervous system can be described both by gross anatomy
Gross anatomy

Gross anatomy is the study of anatomy at the macroscopic. The term gross distinguishes it from other areas of anatomical study, including histology, which must be studied with the aid of a microscope....
, (which describes the parts that are large enough to be seen with the naked eye
Naked eye

The naked eye is a figure of speech referring to human visual perception that is unaided by enhancing equipment, such as a telescope or microscope....
,) and by microanatomy, (which describes the system at a cellular
Cellular

Normally Cellular means mobile device which works using direct satellite where as normal mobile works on towers.Cellular may refer to:*Cellular , a 2004 movie...
 level.) In gross anatomy, the nervous system can be divided into two systems: the central nervous system
Central nervous system

The central nervous system is the part of the nervous system that functions to coordinate the activity of all parts of the bodies of multicellular organisms....
 (CNS) and the peripheral nervous system
Peripheral nervous system

The peripheral nervous system resides or extends outside the central nervous system , which consists of the brain and spinal cord. The main function of the PNS is to connect the CNS to the limbs and organs....
 (PNS).

Central Nervous System


The central nervous system (CNS) is the largest part of the nervous system, and includes the brain
Brain

The brain is the center of the nervous system in all vertebrate, and most invertebrate, animals. Some primitive animals such as cnidarian and echinoderm have a decentralized nervous system without a brain, while sponges lack any nervous system at all....
 and spinal cord
Spinal cord

The spinal cord is a long, thin, tubular bundle of neuron and glia that extends from the brain. The brain and spinal cord together make up the central nervous system....
. The spinal cavity holds and protects the spinal cord, while the head
Head

In anatomy, the head of an animal is the rostral part that usually comprises the brain, eyes, ears, nose, and mouth . Some very simple animals may not have a head, but many bilateria do....
 contains and protects the brain. The CNS is covered by the meninges
Meninges

The meninges is the system of Mesotheliums which envelops the central nervous system. The meninges consist of three layers: the dura mater, the arachnoid mater, and the pia mater....
, a three layered protective coat. The brain is also protected by the skull, and the spinal cord is also protected by the vertebrae.





























Central
nervous
system
Central nervous system

The central nervous system is the part of the nervous system that functions to coordinate the activity of all parts of the bodies of multicellular organisms....

Brain
Brain

The brain is the center of the nervous system in all vertebrate, and most invertebrate, animals. Some primitive animals such as cnidarian and echinoderm have a decentralized nervous system without a brain, while sponges lack any nervous system at all....
Prosencephalon
Prosencephalon

In the anatomy of the brain of vertebrates, the prosencephalon is the rostral-most portion of the brain. The prosencephalon, the mesencephalon , and rhombencephalon are the three primary portions of the brain during early developmental biology of the central nervous system....
Telencephalon
Telencephalon

The cerebrum or telencephalon, together with the diencephalon, constitute the forebrain. It is the most anterior or, especially in humans, most superior region of the vertebrate central nervous system....

Rhinencephalon
Rhinencephalon

In animal anatomy, the rhinencephalon is a part of the brain involved with olfaction.Some references classify other areas of the brain related to perception of smell as rhinencephalon, but the areas of human brains that receive fibers strictly from the olfactory bulb are limited to those of the paleopallium....
,
Amygdala
Amygdala

The are almond-shaped groups of neurons located deep within the medial temporal lobes of the brain in complex vertebrates, including humans. Shown in research to perform a primary role in the processing and memory of emotions, the amygdalae are considered part of the limbic system....
,
Hippocampus
Hippocampus

The hippocampus is a brain structure located inside the medial temporal lobe of the cerebral cortex, and therefore is part of the telencephalon ....
,
Neocortex
Neocortex

The neocortex is a part of the brain of mammals. It is the outer layer of the cerebral hemispheres, and made up of six layers, labelled I to VI ....
,
Lateral ventricles
Lateral ventricles

The lateral ventricles are part of the ventricular system of the brain. Classified as part of the telencephalon, they are the largest of the ventricles....

Diencephalon
Diencephalon

The diencephalon is the region of the brain that includes the thalamus, hypothalamus, epithalamus, prethalamus or subthalamus and pretectum. The diencephalon is located at the midline of the brain, above the mesencephalon of the brain stem....

Epithalamus
Epithalamus

The epithalamus is a Dorsum posterior segment of the diencephalon which includes the habenula, the stria medullaris and the pineal body. Its function is the connection between the limbic system to other parts of the brain....
,
Thalamus
Thalamus

The thalamus is a pair and symmetric part of the brain. It constitutes the main part of the diencephalon....
,
Hypothalamus
Hypothalamus

The hypothalamus is a portion of the brain that contains a number of small nuclei with a variety of functions. One of the most important functions of the hypothalamus is to link the nervous system to the endocrine system via the pituitary gland ....
,
Subthalamus
Subthalamus

The subthalamus is a part of the diencephalon. ...
,
Pituitary gland
Pituitary gland

The pituitary gland, or hypophysis, is an endocrine gland about the size of a pea and weighing 0.5 g . It is a protrusion off the bottom of the hypothalamus at the base of the brain, and rests in a small, bony cavity covered by a Dura mater fold ....
,
Pineal gland
Pineal gland

The pineal gland is a small endocrine system gland in the vertebrate brain. It produces melatonin, a hormone that affects the modulation of wake/sleep patterns and photoperiodic functions....
,
Third ventricle
Third ventricle

The third ventricle is one of four connected fluid-filled cavities comprising the ventricular system within the human brain. It is a median cleft between the two Thalamus, and is filled with cerebrospinal fluid ....

Brain stem
Brain stem

The brain stem is the lower part of the brain, adjoining and structurally continuous with the spinal cord. The brain stem provides the main motor and sensory innervation to the face and neck via the cranial nerves....
Mesencephalon
Mesencephalon

In biological anatomy, the mesencephalon comprises the tectum , tegmentum, the ventricular mesocoelia , and the cerebral peduncles, as well as several nuclei and fasciculi....

Tectum,
Cerebral peduncle
Cerebral peduncle

The cerebral peduncle, by most classifications, is everything in the mesencephalon except the tectum. The region includes the midbrain tegmentum, crus cerebri, substantia nigra and pretectum....
,
Pretectum
Pretectum

The pretectum, also known as the pretectal area, is a region of neurons found between the thalamus and midbrain. It receives binocular vision Sensory system input from Ganglion cell of the eyes, and is the region responsible for maintaining the pupillary light reflex....
,
Mesencephalic duct
Rhombencephalon
Rhombencephalon

The rhombencephalon is a Morphogenesis categorization of portions of the central nervous system in vertebrates.The rhombencephalon can be subdivided in a variable number of transversal swellings called rhombomeres....
Metencephalon
Metencephalon

The metencephalon is a Morphogenesis categorization of portions of the central nervous system. The metencephalon is composed of the pons and the cerebellum; contains a portion of the fourth ventricle; and the trigeminal nerve , abducens nerve , facial nerve , and a portion of the vestibulocochlear nerve ....
 

Pons
Pons

The pons is a structure located on the brain stem. It is cranial to the medulla oblongata, caudal to the midbrain, and ventral to the cerebellum....
,
Cerebellum
Cerebellum

The cerebellum is a region of the brain that plays an important role in the integration of perception, coordination and motoneuron control. In order to coordinate motor control, there are many neural pathways linking the cerebellum with the cerebrum motor cortex and the spinocerebellar tract ....
,
Myelencephalon
Myelencephalon

The myelencephalon is a Morphogenesis categorization of a portion of the central nervous system. The myelencephalon is composed of the medulla oblongata; contains a portion of the fourth ventricle; as well as the glossopharyngeal nerve , vagus nerve , accessory nerve , hypoglossal nerve , and a portion of the vestibulocochlear nerve ....
 
Medulla oblongata
Medulla oblongata

The medulla oblongata is the lower portion of the brainstem. It deals with Autonomic nervous system functions, such as breathing and blood pressure....
Spinal cord
Spinal cord

The spinal cord is a long, thin, tubular bundle of neuron and glia that extends from the brain. The brain and spinal cord together make up the central nervous system....
 


Peripheral nervous system


The PNS is a regional term for the collective nervous structures that do not lie in the CNS. The bodies of the nerve cells lie in the CNS, either in the brain or the spinal cord, and the longer of the cellular processes of these cells, known as axons, extend through the limbs and the flesh of the torso. The large majority of the axons which are commonly called nerves, are considered to be PNS.

The cell bodies of afferent PNS nerves lie in the dorsal root ganglia.

Microanatomy


The nervous system is, on a small scale, primarily made up of neurons. However, glial cell
Glial cell

Glial cells, commonly called neuroglia or simply glia , are non-neuronal cell that provide support and nutrition, maintain homeostasis, form myelin, and participate in signal transmission in the nervous system....
s also play a major role.

Neurons


Neurons are electrically excitable cells in the nervous system that process and transmit information. Neurons are the core components of the brain, the vertebrate spinal cord, the invertebrate ventral nerve cord, and the peripheral nerves. A number of different types of neurons exist: sensory neurons respond to touch, sound, light and numerous other stimuli effecting sensory organs and send signals to the spinal cord and brain, motor neurons receive signals from the brain and spinal cord and cause muscle contractions and affect glands, Interneurons connect neurons to other neurons within the brain and spinal cord.

Glial cells


Glial cells are non-neuron
Neuron

Neurons are responsive cell in the nervous system that process and transmit information by electrochemical Signal . They are the core components of the brain, the vertebrate spinal cord, the invertebrate ventral nerve cord, and the peripheral nerves....
al cells
Cell (biology)

The cell is the structural and functional unit of all known Life organisms. It is the smallest unit of an organism that is classified as living, and is often called the building bricks of life....
 that provide support and nutrition, maintain homeostasis
Homeostasis

Homeostasis is the property of a system, either open system or closed system, that regulates its internal environment and tends to maintain a stable, constant condition....
, form myelin
Myelin

Myelin is an electrically-insulating dielectric material that forms a layer, the myelin sheath. Usually, myelin surrounds only the axon of a neuron....
, and participate in signal transmission in the nervous system
Nervous system

The nervous system is a Neural network of specialized cells that communicate information about an animal's surroundings and itself. It processes this information and causes reactions in other parts of the body....
. In the human brain
Human brain

The human brain is the center of the human nervous system and is a highly complex organ. It has the same general structure as the brains of other mammals, but is over five times as large as the "average brain" of a mammal with the same body size....
, glia are estimated to outnumber neurons by about 10 to 1.

Glial cells provide support and protection for neurons. They are thus known as the "glue" of the nervous system. The four main functions of glial cells are to surround neurons and hold them in place, to supply nutrients and oxygen
Oxygen

Oxygen no O2 produced; 2) O2 produced, but absorbed in oceans & seabed rock; 3) O2 starts to gas out of the oceans, but is absorbed by land surfaces and formation of ozone layer; 4-5) O2 sinks filled and the gas accumulates]]...
 to neurons, to insulate one neuron from another, and to destroy pathogens and remove dead neurons.

Physiological division


A less anatomical but much more functional way of dividing the human nervous system is classification according to the role that the different neural pathways play, regardless of whether or not they cross through the CNS/PNS:

The somatic nervous system
Somatic nervous system

The somatic nervous system is the part of the peripheral nervous system associated with the voluntary control of body movements through the action of skeletal muscles, and with sensory receptor of external stimulus, which helps keep the body in touch with its surroundings ....
 is responsible for coordinating voluntary body movements (i.e. activities that are under conscious control).

The autonomic nervous system
Autonomic nervous system

The autonomic nervous system is the part of the peripheral nervous system that acts as a control system, maintaining human homeostasis in the body....
 is responsible for coordinating involuntary functions, such as breathing and digestion.

In turn, these divisions of the nervous system can be further divided according to the direction in which they conduct nerve impulses:

  • Afferent system by sensory neuron
    Sensory neuron

    Sensory neurons or also known as afferent neurons are neurons that are activated by sensory input , and send projections into the central nervous system that convey sensory information to the brain or spinal cord....
    s, which carries impulses from a somatic receptor to the CNS
  • Efferent system by motor neuron
    Motor neuron

    In vertebrates, the term motor neuron classically applies to neurons located in the central nervous system that project their axons outside the CNS and directly or indirectly control muscles....
    s, which carries impulses from the CNS to an effector
  • Relay system by interneurons (also called "relay neurons"), which transmit impulses between the sensory and motor neurons (both in the CNS and PNS).


The junction between two neurons is called a synapse. There is a very narrow gap (about 20nm in width) between the neurons called the synaptic cleft. This is where an action potential (the "message" being carried by the neurons, also known as the nerve impulse) is transmitted from one neuron to the next. This is achieved by relaying the message across the synaptic cleft using neurotransmitters, which diffuse
Diffusion

Molecular diffusion, often called simply diffusion, is a net transport of molecules from a region of higher concentration to one of lower concentration by random molecular motion....
 across the gap. The neurotransmitters then bind to receptor sites on the neighboring (postsynaptic) neuron, which in turn produces its own electrical/nerve impulse. This impulse is sent to the next synapse, and the cycle repeats itself.

Nerve impulses are a change in ion balance between the inside and outside of a neuron. Because the nervous system uses a combination of electrical and chemical signals, it is incredibly fast. Although the chemical aspect of signaling is much slower than the electrical aspect, a nerve impulse is still fast enough for the reaction time to be negligible in day to day situations. Speed is a necessary characteristic in order for an organism to quickly identify the presence of danger, and thus avoid injury/death. For example, a hand touching a hot stove. If the nervous system was only comprised of chemical signals, the nervous system would not be able to signal the arm to move fast enough to escape dangerous burns. Thus, the speed of the nervous system is evolutionarily valuable, and is in fact a necessity for life.

Development


Some landmarks of embryo
Embryo

An embryo is a multicellular organism ploidy eukaryote in its earliest stage of development, from the time of first cell division until birth, Egg , or germination....
nic neural development include the birth and differentiation
Cellular differentiation

In developmental biology, cellular differentiation is the process by which a less specialized cell becomes a more specialized cell type. Differentiation occurs numerous times during the development of a multicellular organism as the organism changes from a single zygote to a complex system of Tissue and cell types....
 of neuron
Neuron

Neurons are responsive cell in the nervous system that process and transmit information by electrochemical Signal . They are the core components of the brain, the vertebrate spinal cord, the invertebrate ventral nerve cord, and the peripheral nerves....
s from stem cell precursors, the migration
Cellular migration

Cellular migration is the movement of Cell in the body to their proper position....
 of immature neurons from their birthplaces in the embryo to their final positions, outgrowth of axon
Axon

An axon or nerve fiber is a long, slender projectionof a nerve cell, or neuron, that conducts action potentialaway from the neuron's cell body or soma....
s from neurons and guidance
Axon guidance

Axon guidance is a subfield of neural development concerning the process by which neurons send out axons to reach the correct targets. Axons often follow very precise paths in the nervous system, and how they manage to find their way so accurately is being researched....
 of the motile growth cone
Growth cone

A growth cone is a dynamic, actin-supported extension of a developing axon seeking its synapse target. Their existence was originally proposed by Spanish people histology Santiago Ram?n y Cajal based upon stationary images he observed under the microscope....
 through the embryo towards postsynaptic partners, the generation of synapses between these axons and their postsynaptic partners, and finally the lifelong changes
Synaptic plasticity

In neuroscience, synaptic plasticity is the ability of the connection, or synapse, between two neurons to change in Synapse#Synaptic strength. There are several underlying mechanisms that cooperate to achieve synaptic plasticity, including changes in the quantity of neurotransmitters released into a synapse and changes in how effectively cell...
 in synapses which are thought to underlie learning and memory.

Importance


The evolution of a complex nervous system makes it possible for various animal species to have advanced perception abilities like sight, complex social interactions, rapid coordination of other organ systems, and integrated processing of many concurrent signals. In humans, the advanced development of the nervous system makes it possible to have language, abstract representation of concepts, transmission of culture, and many other outcomes of human society that would not be possible without our brains.

Many people have lost basic motor skills and other skills because of spinal cord injuries. If this portion is damaged, the biggest nerve and the most important one gets damaged. This leads to paralysis or other permanent damage. Physical lesions or genetic abnormalities of the brain can also lead to major harm.

Abilities


The nervous system enables basic motor skills and sensing. The five classical senses (touch, taste, sight, smell, and hearing) are powered by the nervous system as are others such as equilibrioception
Equilibrioception

Equilibrioception or sense of balance is one of the physiology senses. It helps prevent humans and animals from falling over when walking or standing still....
 (the sensing of gravity), nociception
Nociception

Nociception is defined as "the neural processes of encoding and processing noxious stimuli." It is the afferent activity produced in the peripheral and central nervous system by stimuli that have the potential to damage tissue....
 (the sensing of pain), and proprioception
Proprioception

Proprioception ; from Latin proprius, meaning "one's own" and perception) is the sense of the relative position of neighbouring parts of the body....
 (the sensing of relative limb location and motion, as when touching the nose with closed eyes). Inhibition of these senses would retard basic motor skills.

Non-humans


Vertebrates

The nervous system of all vertebrate animals
Vertebrate

Vertebrates are members of the subphylum Vertebrata, chordates with Vertebras or Vertebral columns. The grouping sometimes includes the hagfish, which have no vertebrae, but are genetically quite closely related to lampreys, which do have vertebrae....
 is often divided into the central nervous system (CNS) and the peripheral nervous system (PNS). The CNS consists of the brain and spinal cord.

Worms


Planaria, a type of flatworm
Flatworm

The flatworms, known in scientific literature as Platyhelminthes are a Phylum of relatively simple bilaterian, Segmentation , soft-bodied invertebrate animals....
, have dual nerve cord
Ventral nerve cord

The ventral nerve cords make up the nervous system of some phylum of the invertebrates particularly within the nematodes, annelids and the arthropods....
s running along the length of the body and merging at the tail and the mouth. These nerve cords are connected by transverse
Transverse

Transverse may refer to:*Transversality, a concept related to the intersection of manifolds in topology*Transverse City, an album by Warren Zevon...
 nerves like the rungs of a ladder. These transverse nerves help coordinate the two sides of the animal. Two large ganglia at the head end function similar to a simple brain. Photoreceptor
Photoreceptor

A photoreceptor, or photoreceptor cell, is a specialized type of neuron found in the eye's retina that is capable of phototransduction....
s on the animal's eyespots provide sensory information on light and dark.

The nervous system of the roundworm Caenorhabditis elegans
Caenorhabditis elegans

'Caenorhabditis elegans' is a free-living, transparent nematode , about 1 mm in length, which lives in temperate soil environments. Research into the molecular biology and developmental biology of C....
 has been mapped out to the cellular level. Every neuron and its cellular lineage
Fate mapping

Fate mapping is a wikt:technique that is used to show how a cell or tissue moves and what it will become during normal development. Fate mapping was developed by Walter Vogt as a means by which to trace the development of specific regions of the early embryo....
 has been recorded and most, if not all, of the neural connections are known. In this species, the nervous system is sexually dimorphic; the nervous systems of the two sexes, males and hermaphrodites, have different numbers of neurons and groups of neurons that perform sex-specific functions. In C. elegans, males have exactly 383 neurons, while hermaphrodites have exactly 302 neurons

Arthropoda


Arthropod
Arthropod

Arthropods are animals belonging to the Scientific classification Arthropoda , and include the insects, arachnids, crustaceans, and others....
s, such as insect
Insect

Insects are the biggest class of arthropods and the only ones with wings. They are the most diverse group of animals on the planet. They are most diverse at the equator and their diversity declines toward the poles....
s and crustacean
Crustacean

Crustaceans are a large group of arthropods, comprising almost 52,000 described species , and are usually treated as a subphylum . They include various familiar animals, such as crabs, lobsters, crayfish, shrimp, krill and barnacles....
s, have a nervous system made up of a series of ganglia
Ganglion

In anatomy, a ganglion is a biological tissue.Cells found in a ganglion are called ganglion cells, though this term is also sometimes used to refer specifically to Retinal ganglion cells....
, connected by a ventral nerve cord
Ventral nerve cord

The ventral nerve cords make up the nervous system of some phylum of the invertebrates particularly within the nematodes, annelids and the arthropods....
 made up of two parallel connectives running along the length of the belly
Belly

Belly may refer to:* The abdomen, the part of the body between the pelvis and the thorax or, similarly, to the stomach**A beer belly, an overhang of fat above the waist, presumably caused by regular beer ingestion....
 . Typically, each body segment has one ganglion
Ganglion

In anatomy, a ganglion is a biological tissue.Cells found in a ganglion are called ganglion cells, though this term is also sometimes used to refer specifically to Retinal ganglion cells....
 on each side, though some ganglia are fused to form the brain and other large ganglia .

The head segment contains the brain
Brain

The brain is the center of the nervous system in all vertebrate, and most invertebrate, animals. Some primitive animals such as cnidarian and echinoderm have a decentralized nervous system without a brain, while sponges lack any nervous system at all....
, also known as the supraesophageal ganglion. In the insect nervous system
Insect

Insects are the biggest class of arthropods and the only ones with wings. They are the most diverse group of animals on the planet. They are most diverse at the equator and their diversity declines toward the poles....
, the brain is anatomically divided into the protocerebrum, deutocerebrum, and tritocerebrum. Immediately behind the brain is the subesophageal ganglion
Subesophageal ganglion

Insects The subesophageal ganglion of insects is composed of three pairs of fused ganglia. It controls the mouthparts, the salivary glands and certain muscles....
, which is composed of three pairs of fused ganglia. It controls the mouthparts
Mouthparts

The mouthparts of arthropods have evolution into a number of forms, each adaptation to a different style or mode of feeding. Most mouthparts represent modified, paired appendages, which in ancestral forms would have appeared more like legs than mouthparts....
, the salivary glands and certain muscle
MUSCLE

MUSCLE is public domain, multiple sequence alignment software for protein and nucleotide sequences.MUSCLE is integrated into UGENE bioinformatics tool as a plugin....
s.

Many arthropods have well-developed sensory
Sense

Senses are the physiological methods of perception. The senses and their operation, classification, and theory are overlapping topics studied by a variety of fields, most notably neuroscience, cognitive psychology , and philosophy of perception....
 organs, including compound eyes for vision and antennae
Antenna (biology)

Antennae are paired appendages connected to the front-most morphogenesis of arthropods. In crustaceans, they are biramous and present on the first two segments of the head, with the smaller pair known as antennules....
 for olfaction
Olfaction

Olfaction refers to the sense of smell. This sense is mediated by specialized sensory cells of the nasal cavity of vertebrates, and, by analogy, sensory cells of the antennae of invertebrates....
 and pheromone
Pheromone

A pheromone is a chemical that triggers a natural behavioral response in another member of the opposite gender of the same species. There are alarm signal pheromones, food trail pheromones, sex pheromones, and many others that affect behavior or physiology....
 sensation. The sensory information from these organs is processed by the brain.

Development


Neural development in most species have many similarities with neural development in humans
Neural development in humans

The study of neural development draws on both neuroscience and developmental biology to describe the cellular and molecular mechanisms by which complex nervous systems emerge during morphogenesis and throughout life....
.

As shown in a 2008 study, one factor common to all bilateral
Symmetry (biology)

Symmetry in biology is the balanced distribution of duplicate body parts or shapes. The body plans of most multicellular organisms exhibit some form of symmetry, either radial symmetry or bilateral symmetry or glide symmetry....
 organisms (including humans) is a familiy of secreted signaling molecules called neurotrophins
Neurotrophin

Neurotrophins are a family of proteins that induce the survival, development and function of neurons.They belong to a class of growth factors, exocytosis proteins, which are capable of signaling particular cells to survive, differentiate, or grow....
 which regulate the growth and survival of neurons
Neuron

Neurons are responsive cell in the nervous system that process and transmit information by electrochemical Signal . They are the core components of the brain, the vertebrate spinal cord, the invertebrate ventral nerve cord, and the peripheral nerves....
. Zhu et al. identified DNT1, the first neurotrophin found in flies
Fly

True flies are insects of the Order Diptera , possessing a single pair of insect wing on the mesothorax and a pair of halteres, derived from the hind wings, on the metathorax....
. DNT1 shares structural similarity with all known neurotrophins and is a key factor in the fate of neurons in Drosophila
Drosophila

Drosophila is a genus of small fly, belonging to the family Drosophilidae, whose members are often called "fruit flies" or more appropriately pomace flies, vinegar flies, or wine flies, a reference to the characteristic of many species to linger around overripe or rotting fruit....
. Because neurotrophins have now been identified in both vertebrate and invertebrates, this evidence suggests that neurotrophins were present in an ancestor common to bilateral organisms and may represent a common mechanism for nervous system formation.

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