Mycobacterium murale
Encyclopedia
Mycobacterium murale

Description

Gram-positive, nonmotile and acid-fast rods or coccobacilli (0.4-0.5 µm x 0.6-1.4 µm).

Colony characteristics
Smooth and scotochromogenic colonies of saffron yellow color.

Physiology
  • Growth on Middlebrook 7H10 agar at 10-37°C, optimum at 30°C within 5 days.
  • Susceptible to amikacin
    Amikacin
    Amikacin is an aminoglycoside antibiotic used to treat different types of bacterial infections. Amikacin works by binding to the bacterial 30S ribosomal subunit, causing misreading of mRNA and leaving the bacterium unable to synthesize proteins vital to its growth.-Administration:Amikacin may be...

    , azithromycin
    Azithromycin
    Azithromycin is an azalide, a subclass of macrolide antibiotics. Azithromycin is one of the world's best-selling antibiotics...

    , ciprofloxacin
    Ciprofloxacin
    Ciprofloxacin is a synthetic chemotherapeutic antibiotic of the fluoroquinolone drug class.It is a second-generation fluoroquinolone antibacterial. It kills bacteria by interfering with the enzymes that cause DNA to rewind after being copied, which stops synthesis of DNA and of...

    , clarithromycin
    Clarithromycin
    Clarithromycin is a macrolide antibiotic used to treat pharyngitis, tonsillitis, acute maxillary sinusitis, acute bacterial exacerbation of chronic bronchitis, pneumonia , skin and skin structure infections...

     and ethambutol
    Ethambutol
    Ethambutol is a bacteriostatic antimycobacterial drug prescribed to treat tuberculosis. It is usually given in combination with other tuberculosis drugs, such as isoniazid, rifampicin and pyrazinamide....

    .
  • Resistant to isoniazid
    Isoniazid
    Isoniazid , also known as isonicotinylhydrazine , is an organic compound that is the first-line antituberculosis medication in prevention and treatment. It was first discovered in 1912, and later in 1951 it was found to be effective against tuberculosis by inhibiting its mycolic acid...

    .


Differential characteristics
  • Mycobacterium murale and Mycobacterium tokaiense
    Mycobacterium tokaiense
    Mycobacterium tokaiense is a species of Mycobacterium....

    share an identical 5'-16S rDNA sequence
  • However the ITS sequence of both species differs.

Type strain

  • First isolated from water-damaged indoor building material, Finland.

Strain MA112/96 = CCUG 39728 = CIP 105980 = DSM 44340 = HAMBI 2320 = JCM 13392.
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