Description

• Highly mucoid behavior of most strains on solid agar. Smooth and off-white on Middlebrook 7H10 agar

• Rapid growth on Middlebrook 7H10 at 28°C to 37°C, but not at 42°C, within 2 – 4 days.
• Susceptible to amikacin
  Amikacin
  Amikacin is an aminoglycoside antibiotic used to treat different types of bacterial infections. Amikacin works by binding to the bacterial 30S ribosomal subunit, causing misreading of mRNA and leaving the bacterium unable to synthesize proteins vital to its growth.-Administration:Amikacin may be...
  
  , imipenem
  Imipenem
  Imipenem is an intravenous β-lactam antibiotic developed in 1980. It has an extremely broad spectrum of activity.Imipenem belongs to the subgroup of carbapenems. It is derived from a compound called thienamycin, which is produced by the bacterium Streptomyces cattleya...
  
  , cefoxitin
  Cefoxitin
  Cefoxitin is a cephamycin antibiotic developed by Merck & Co., Inc., often grouped with the second−generation cephalosporins. It is sold under the brand name Mefoxin.- Microbiology :...
  
  , clarithromycin
  Clarithromycin
  Clarithromycin is a macrolide antibiotic used to treat pharyngitis, tonsillitis, acute maxillary sinusitis, acute bacterial exacerbation of chronic bronchitis, pneumonia , skin and skin structure infections...
  
   and ciprofloxacin
  Ciprofloxacin
  Ciprofloxacin is a synthetic chemotherapeutic antibiotic of the fluoroquinolone drug class.It is a second-generation fluoroquinolone antibacterial. It kills bacteria by interfering with the enzymes that cause DNA to rewind after being copied, which stops synthesis of DNA and of...
  
  .
• Resistant to isoniazid
  Isoniazid
  Isoniazid , also known as isonicotinylhydrazine , is an organic compound that is the first-line antituberculosis medication in prevention and treatment. It was first discovered in 1912, and later in 1951 it was found to be effective against tuberculosis by inhibiting its mycolic acid...
  
   and rifampin.

Pathogenesis

• Posttraumatic skin infections,
• catheter
  Catheter
  In medicine, a catheter is a tube that can be inserted into a body cavity, duct, or vessel. Catheters thereby allow drainage, administration of fluids or gases, or access by surgical instruments. The process of inserting a catheter is catheterization...
  
   sepsis
  Sepsis
  Sepsis is a potentially deadly medical condition that is characterized by a whole-body inflammatory state and the presence of a known or suspected infection. The body may develop this inflammatory response by the immune system to microbes in the blood, urine, lungs, skin, or other tissues...
  
   and respiratory isolates without clinical significance except in immunocompromised hosts.
• Biosafety level
  Biosafety level
  A biosafety level is the level of the biocontainment precautions required to isolate dangerous biological agents in an enclosed facility. The levels of containment range from the lowest biosafety level 1 to the highest at level 4 . In the United States, the Centers for Disease Control and...
  
   2

Type strain

• First isolated in 1976 during an outbreak of peritonitis
  Peritonitis
  Peritonitis is an inflammation of the peritoneum, the serous membrane that lines part of the abdominal cavity and viscera. Peritonitis may be localised or generalised, and may result from infection or from a non-infectious process.-Abdominal pain and tenderness:The main manifestations of...
  
   associated with automated peritoneal dialysis
  Dialysis
  In medicine, dialysis is a process for removing waste and excess water from the blood, and is primarily used to provide an artificial replacement for lost kidney function in people with renal failure...
  
  machines in the north-western United States.
• Strain ATCC 49650 = CCUG 47451 = CIP 105223 = DSM 44625 = JCM 13575.