Mycobacterium mageritense
Encyclopedia
Mycobacterium mageritense
Etymology
: Magerit, is Arabic for Madrid
, where the it was first isolated from human sputum
.
Colony characteristics
Physiology
Differential characteristics
Strain 938 = ATCC 700351 = CCUG 37984 = CIP 104973 = DSM 44476 = JCM 12375.
Etymology
Etymology
Etymology is the study of the history of words, their origins, and how their form and meaning have changed over time.For languages with a long written history, etymologists make use of texts in these languages and texts about the languages to gather knowledge about how words were used during...
: Magerit, is Arabic for Madrid
Madrid
Madrid is the capital and largest city of Spain. The population of the city is roughly 3.3 million and the entire population of the Madrid metropolitan area is calculated to be 6.271 million. It is the third largest city in the European Union, after London and Berlin, and its metropolitan...
, where the it was first isolated from human sputum
Sputum
Sputum is mucus that is coughed up from the lower airways. It is usually used for microbiological investigations of respiratory infections....
.
Description
Gram-positive, nonmotile and strongly acid-fast rods.Colony characteristics
- Smooth, mucoid and nonphotochromogenic colonies.
Physiology
- Rapid growth on Löwenstein-Jensen medium at 22°C, 30°C, 37°C and 45°C within 2–4 days.
- Optimum growth at 30°C and 37°C.
- Resistant to isoniazidIsoniazidIsoniazid , also known as isonicotinylhydrazine , is an organic compound that is the first-line antituberculosis medication in prevention and treatment. It was first discovered in 1912, and later in 1951 it was found to be effective against tuberculosis by inhibiting its mycolic acid...
, cycloserineCycloserineCycloserine is an antibiotic effective against Mycobacterium tuberculosis. For the treatment of tuberculosis, it is classified as a second line drug, i.e...
, capreomycinCapreomycinCapreomycin is a peptide antibiotic, commonly grouped with the aminoglycosides, which is given in combination with other antibiotics for tuberculosis...
, pyrazinamidePyrazinamidePyrazinamide is a drug used to treat tuberculosis. The drug is largely bacteriostatic, but can be bacteriocidal on actively replicating tuberculosis bacteria.-Abbreviations:...
, and thiosemicarbazone - Most strains are also resistant to ethambutolEthambutolEthambutol is a bacteriostatic antimycobacterial drug prescribed to treat tuberculosis. It is usually given in combination with other tuberculosis drugs, such as isoniazid, rifampicin and pyrazinamide....
.
Differential characteristics
- Characterised by unique hsp65 gene, 16S rDNA and sodA sequences. *Closely related to M. fortuitum and M. peregrinum at the DNA homology level.
- Differentiation from M. fortuitum by its growth at 45°C and by its use of mannitol as a sole carbon source.
Type strain
- First isolated from human sputum in Madrid
Strain 938 = ATCC 700351 = CCUG 37984 = CIP 104973 = DSM 44476 = JCM 12375.