Description

• Smooth colonies, with bright yellow pigmentation 1-2mm in diameter.

• Slow growth on Löwenstein-Jensen medium at temperatures between 22°C and 37°C within 3–4 weeks.
• Generally resistant to isoniazid
  Isoniazid
  Isoniazid , also known as isonicotinylhydrazine , is an organic compound that is the first-line antituberculosis medication in prevention and treatment. It was first discovered in 1912, and later in 1951 it was found to be effective against tuberculosis by inhibiting its mycolic acid...
  
  , rifampin, ethambutol
  Ethambutol
  Ethambutol is a bacteriostatic antimycobacterial drug prescribed to treat tuberculosis. It is usually given in combination with other tuberculosis drugs, such as isoniazid, rifampicin and pyrazinamide....
  
   and streptomycin
  Streptomycin
  Streptomycin is an antibiotic drug, the first of a class of drugs called aminoglycosides to be discovered, and was the first antibiotic remedy for tuberculosis. It is derived from the actinobacterium Streptomyces griseus. Streptomycin is a bactericidal antibiotic. Streptomycin cannot be given...
  
  .

• Phylogenetic analysis, based on an evaluation of 16S rDNA sequences, places M. lentiflavum in an intermediate position between rapidly and slowly growing mycobacteria, closely related to Mycobacterium simiae and Mycobacterium genavense
  Mycobacterium genavense
  -Description:A slow-growing subspecies of Mycobacterium.Nonmotile, acid-fast coccobacilli . No formation of spores, capsules or aerial hyphae.Colony characteristics...
  
  .

Pathogenesis

• In young children with cervical lymphadenitis and in immunocompromised patients
• One case of verterbral osteomyelitis
  Osteomyelitis
  Osteomyelitis simply means an infection of the bone or bone marrow...
  
   reported
• Biosafety level
  Biosafety level
  A biosafety level is the level of the biocontainment precautions required to isolate dangerous biological agents in an enclosed facility. The levels of containment range from the lowest biosafety level 1 to the highest at level 4 . In the United States, the Centers for Disease Control and...
  
   2

Type strain

• First isolated from a patient with spondylodiscitis
  Spondylodiscitis
  Spondylodiscitis is a combination of discitis and spondylitis , the latter generally involving the areas adjacent to the intervertebral disc space.-Causes:...
  
   (verterbral osteomyelitis
  Osteomyelitis
  Osteomyelitis simply means an infection of the bone or bone marrow...
  
  ). Further isolates from clinical specimens were obtained due to the use of contaminated bronchoscopes. Also recovered from gastric juice, sputum
  Sputum
  Sputum is mucus that is coughed up from the lower airways. It is usually used for microbiological investigations of respiratory infections....
  
   and urine
  Urine
  Urine is a typically sterile liquid by-product of the body that is secreted by the kidneys through a process called urination and excreted through the urethra. Cellular metabolism generates numerous by-products, many rich in nitrogen, that require elimination from the bloodstream...
  
  samples.