Mycobacterium goodii
Encyclopedia
Mycobacterium goodii
Colony characteristics
Physiology
Differential characteristics
of the heel
(USA).
Strain MO69 = ATCC 700504 = CIP 106349 = DSM 44492 = JCM 12689.
Mycobacterium goodii was previously known as Mycobacterium smegmatis
group 2.
Description
Gram-positive, nonmotile and acid-fast rods.Colony characteristics
- Smooth to mucoid, off-white to cream coloured colonies. Yellow to orange pigment produced in 78% of all strains, after 10–14 days incubation.
Physiology
- Rapid growth on Middlebrook 7H10 and trypticase soy agarTrypticase soy agarTrypticase soy agar is a bacterial growth medium.The medium contains enzymatic digests of casein and soybean meal which provides amino acids and other nitrogenous substances making it a nutritious medium for a variety of organisms. Glucose is the energy source. Sodium chloride maintains the osmotic...
at 30°C, 35°C and 45°C within 2–4 days. - Susceptible to amikacinAmikacinAmikacin is an aminoglycoside antibiotic used to treat different types of bacterial infections. Amikacin works by binding to the bacterial 30S ribosomal subunit, causing misreading of mRNA and leaving the bacterium unable to synthesize proteins vital to its growth.-Administration:Amikacin may be...
, ethambutolEthambutolEthambutol is a bacteriostatic antimycobacterial drug prescribed to treat tuberculosis. It is usually given in combination with other tuberculosis drugs, such as isoniazid, rifampicin and pyrazinamide....
, sulfamethoxazoleSulfamethoxazoleSulfamethoxazole is a sulfonamide bacteriostatic antibiotic.It is most often used as part of a synergistic combination with trimethoprim in a 5:1 ratio in co-trimoxazole , also known under trade names such as Bactrim, Septrin, or Septra; in Eastern Europe it is marketed as Biseptol...
. - Intermediate susceptible to ciprofloxacinCiprofloxacinCiprofloxacin is a synthetic chemotherapeutic antibiotic of the fluoroquinolone drug class.It is a second-generation fluoroquinolone antibacterial. It kills bacteria by interfering with the enzymes that cause DNA to rewind after being copied, which stops synthesis of DNA and of...
, doxycyclineDoxycyclineDoxycycline INN is a member of the tetracycline antibiotics group, and is commonly used to treat a variety of infections. Doxycycline is a semisynthetic tetracycline invented and clinically developed in the early 1960s by Pfizer Inc. and marketed under the brand name Vibramycin. Vibramycin...
and tobramycin. - Variable susceptible to cefmetazoleCefmetazoleCefmetazole is a cephalosporin antibiotic, usually grouped with the second-generation cephalosporins.-Adverse effects:The chemical structure of cefmetazole, like that of several other cephalosporins, contains an N-methylthiotetrazole side chain...
, cefoxitinCefoxitinCefoxitin is a cephamycin antibiotic developed by Merck & Co., Inc., often grouped with the second−generation cephalosporins. It is sold under the brand name Mefoxin.- Microbiology :...
and clarithromycinClarithromycinClarithromycin is a macrolide antibiotic used to treat pharyngitis, tonsillitis, acute maxillary sinusitis, acute bacterial exacerbation of chronic bronchitis, pneumonia , skin and skin structure infections...
. - Resistant to isoniazidIsoniazidIsoniazid , also known as isonicotinylhydrazine , is an organic compound that is the first-line antituberculosis medication in prevention and treatment. It was first discovered in 1912, and later in 1951 it was found to be effective against tuberculosis by inhibiting its mycolic acid...
and rifampicinRifampicinRifampicin or rifampin is a bactericidal antibiotic drug of the rifamycin group. It is a semisynthetic compound derived from Amycolatopsis rifamycinica ...
.
Differential characteristics
- Comparable clinical settings to M. smegmatis and members of the M. fortuitum complex.
Pathogenesis
- Production of post-traumatic woundWoundA wound is a type of injury in which skin is torn, cut or punctured , or where blunt force trauma causes a contusion . In pathology, it specifically refers to a sharp injury which damages the dermis of the skin.-Open:...
infections especially those following open fractures and with associated osteomyelitisOsteomyelitisOsteomyelitis simply means an infection of the bone or bone marrow...
and chronic lipoid pneumoniaPneumoniaPneumonia is an inflammatory condition of the lung—especially affecting the microscopic air sacs —associated with fever, chest symptoms, and a lack of air space on a chest X-ray. Pneumonia is typically caused by an infection but there are a number of other causes...
.
Type strain
First isolated from a patient with a post-traumatic osteomyelitisOsteomyelitis
Osteomyelitis simply means an infection of the bone or bone marrow...
of the heel
Heel
In human anatomy, the heel is the prominence at the posterior end of the foot. It is based on the projection of one bone, the calcaneus or heel bone, behind the articulation of the bones of the lower leg.- Human anatomy :...
(USA).
Strain MO69 = ATCC 700504 = CIP 106349 = DSM 44492 = JCM 12689.
Mycobacterium goodii was previously known as Mycobacterium smegmatis
Mycobacterium smegmatis
Mycobacterium smegmatis is 3.0 to 5.0 µm long with a bacillus shape, an acid-fast bacterial species in the phylum Actinobacteria. It can be stained by Ziehl-Neelsen method and the auramine-rhodamine fluorescent method. It was first reported in November 1884 by Lustgarten, who found a bacillus...
group 2.