Mycobacterium gastri
Encyclopedia
Mycobacterium gastri

Description

Moderately long to long, Gram-positive, nonmotile and acid-fast rods.

Colony characteristics
  • Nonchromogenic, smooth to rough, white colonies on Löwenstein-Jensen medium and smooth or somewhat granular on Middlebrook 7H10 agar.


Physiology
  • Growth on Löwenstein-Jensen medium or on Middlebrook 7H10
    Middlebrook 7H10 Agar
    Middlebrook 7H10 Agar is a solid growth medium specially used for culture of Mycobacterium, notably Mycobacterium tuberculosis. It has been reported that the 7H10 medium tends to grow fewer contaminants than the egg-based media commonly used for the cultivation of mycobacteria.- Composition :*...

     agar at 37°C, (temperature range 25°C-40°C), within 7 or more days.
  • Does not grow in the presence of ethambutol
    Ethambutol
    Ethambutol is a bacteriostatic antimycobacterial drug prescribed to treat tuberculosis. It is usually given in combination with other tuberculosis drugs, such as isoniazid, rifampicin and pyrazinamide....

     or isoniazid
    Isoniazid
    Isoniazid , also known as isonicotinylhydrazine , is an organic compound that is the first-line antituberculosis medication in prevention and treatment. It was first discovered in 1912, and later in 1951 it was found to be effective against tuberculosis by inhibiting its mycolic acid...

    .


Differential characteristics
  • Closely related to M. kansasii
  • M. gastri and M. kansasii share an identical 16S rDNA sequence. Species differentiation is possible by differences in the ITS and hsp65 sequences.
  • M. kansasii produces a photochromogenic yellow pigment.
  • AccuProbes for M. kansasii are negative.

Pathogenesis

  • Casual resident of human stomachs, but not considered an etiologic agent of disease.
  • Biosafety level
    Biosafety level
    A biosafety level is the level of the biocontainment precautions required to isolate dangerous biological agents in an enclosed facility. The levels of containment range from the lowest biosafety level 1 to the highest at level 4 . In the United States, the Centers for Disease Control and...

    1

Type strain

  • First isolated from human gastric specimen. Also found in soil.

Strain ATCC 15754 = CCUG 20995 = CIP 104530 = DSM 43505 = JCM 12407.
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