Mycobacterium conspicuum
Encyclopedia
Mycobacterium conspicuum
and nonmotile acid-fast coccobacilli. Does not form spores, capsules or aerial hyphae.
Colony characteristics
Physiology
infected patients in Germany
.
Strain 3895/92 = ATCC
700090 = CIP 105165 = DSM 44136.
Description
Gram-positiveGram-positive
Gram-positive bacteria are those that are stained dark blue or violet by Gram staining. This is in contrast to Gram-negative bacteria, which cannot retain the crystal violet stain, instead taking up the counterstain and appearing red or pink...
and nonmotile acid-fast coccobacilli. Does not form spores, capsules or aerial hyphae.
Colony characteristics
- Dysgonic and nonphotochromogenic, pale yellow coloniesColony (biology)In biology, a colony reference to several individual organisms of the same species living closely together, usually for mutual benefit, such as stronger defense or the ability to attack bigger prey. Some insects live only in colonies...
on Löwenstein-Jensen agar.
Physiology
- Slow growth on Löwenstein-Jensen medium at temperatures between 22°C and 31°C after 2–3 weeks.
- Susceptible to ethambutolEthambutolEthambutol is a bacteriostatic antimycobacterial drug prescribed to treat tuberculosis. It is usually given in combination with other tuberculosis drugs, such as isoniazid, rifampicin and pyrazinamide....
, rifampin, streptomycinStreptomycinStreptomycin is an antibiotic drug, the first of a class of drugs called aminoglycosides to be discovered, and was the first antibiotic remedy for tuberculosis. It is derived from the actinobacterium Streptomyces griseus. Streptomycin is a bactericidal antibiotic. Streptomycin cannot be given...
, resistant to pyrazinamidePyrazinamidePyrazinamide is a drug used to treat tuberculosis. The drug is largely bacteriostatic, but can be bacteriocidal on actively replicating tuberculosis bacteria.-Abbreviations:...
. - Synthesis of α- and keto-mycolates and wax esters.
- no tolerance to 5% NaClSodium chlorideSodium chloride, also known as salt, common salt, table salt or halite, is an inorganic compound with the formula NaCl. Sodium chloride is the salt most responsible for the salinity of the ocean and of the extracellular fluid of many multicellular organisms...
, positive for Tween 80 hydrolysis and for 10-day-arylsulfatase. Negative for production of nicotinic acid, acetamidase, benzamidase, ureaseUreaseUrease is an enzyme that catalyzes the hydrolysis of urea into carbon dioxide and ammonia. The reaction occurs as follows:In 1926, James Sumner showed that urease is a protein. Urease is found in bacteria, yeast, and several higher plants. The structure of urease was first solved by P.A...
, isonicotinamidase, nicotinamidase, pyrazinamidase, succinidamidase, nitrate reductaseNitrate reductaseNitrate reductases are molybdoenzymes that reduce nitrate to nitrite .* Eukaryotic nitrate reductases are part of the sulfite oxidase family of molybdoenzymes....
and telluriteTelluriteTellurite is a rare oxide mineral composed of tellurium dioxide .It occurs as prismatic to acicular transparent yellow to white orthorhombic crystals. It occurs in the oxidation zone of mineral deposits in association with native tellurium, emmonsite and other tellurium minerals. Its name comes...
reduction.
Type Strain
First isolated from two male HIVHIV
Human immunodeficiency virus is a lentivirus that causes acquired immunodeficiency syndrome , a condition in humans in which progressive failure of the immune system allows life-threatening opportunistic infections and cancers to thrive...
infected patients in Germany
Germany
Germany , officially the Federal Republic of Germany , is a federal parliamentary republic in Europe. The country consists of 16 states while the capital and largest city is Berlin. Germany covers an area of 357,021 km2 and has a largely temperate seasonal climate...
.
Strain 3895/92 = ATCC
American Type Culture Collection
The American Type Culture Collection is a private, not-for-profit biological resource center whose mission focuses on the acquisition, authentication, production, preservation, development and distribution of standard reference microorganisms, cell lines and other materials for research in the...
700090 = CIP 105165 = DSM 44136.