Mycobacterium avium avium
Encyclopedia
Mycobacterium avium subsp. avium

Type strain
Biological type
In biology, a type is one particular specimen of an organism to which the scientific name of that organism is formally attached...

: strain ATCC
American Type Culture Collection
The American Type Culture Collection is a private, not-for-profit biological resource center whose mission focuses on the acquisition, authentication, production, preservation, development and distribution of standard reference microorganisms, cell lines and other materials for research in the...

 25291 = CCUG 20992 = CIP 104244 = DSM 44156 = NCTC 13034.

The subspecies name Mycobacterium avium subsp. avium Chester 1901 is automatically created by the valid publication of Mycobacterium avium subsp. paratuberculosis (Bergey et al. 1923) and the valid publication of Mycobacterium avium subsp. silvaticum Thorel et al. 1990.

Based on differences in IS1245 RFLP, 16S-23S rDNA
Ribosomal DNA
Ribosomal DNA codes for ribosomal RNA. The ribosome is an intracellular macromolecule that produces proteins or polypeptide chains. The ribosome itself consists of a composite of proteins and RNA. As shown in the figure, rDNA consists of a tandem repeat of a unit segment, an operon, composed of...

 ITS and growth temperature, Mijs et al. 2002 propose to reserve the designation Mycobacterium avium subsp. avium for bird
Bird
Birds are feathered, winged, bipedal, endothermic , egg-laying, vertebrate animals. Around 10,000 living species and 188 families makes them the most speciose class of tetrapod vertebrates. They inhabit ecosystems across the globe, from the Arctic to the Antarctic. Extant birds range in size from...

-type isolates. These authors suggest, but not formally propose, the designation "Mycobacterium avium subsp. hominissuis" for the isolates from human
Human
Humans are the only living species in the Homo genus...

s and pig
Pig
A pig is any of the animals in the genus Sus, within the Suidae family of even-toed ungulates. Pigs include the domestic pig, its ancestor the wild boar, and several other wild relatives...

s.

Epidemiology

Present mainly in cattle
Cattle
Cattle are the most common type of large domesticated ungulates. They are a prominent modern member of the subfamily Bovinae, are the most widespread species of the genus Bos, and are most commonly classified collectively as Bos primigenius...

 and humans with an immunocompromised disorder, e.g. AIDS
AIDS
Acquired immune deficiency syndrome or acquired immunodeficiency syndrome is a disease of the human immune system caused by the human immunodeficiency virus...

. Sometimes, it is transmitted to man by drinking unpasteurized cow milk
Milk
Milk is a white liquid produced by the mammary glands of mammals. It is the primary source of nutrition for young mammals before they are able to digest other types of food. Early-lactation milk contains colostrum, which carries the mother's antibodies to the baby and can reduce the risk of many...

.
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