Mycobacterium alvei
Encyclopedia
Mycobacterium alvei
, nonmotile and acid-fast
rods (1-3 µm x 0.5-0.7 µm).
Colony characteristics
Physiology
Differential characteristics
Strain CR-21 = ATCC 51304 = CIP 103464 = DSM 44176 = JCM 12272.
Description
Gram-positiveGram-positive
Gram-positive bacteria are those that are stained dark blue or violet by Gram staining. This is in contrast to Gram-negative bacteria, which cannot retain the crystal violet stain, instead taking up the counterstain and appearing red or pink...
, nonmotile and acid-fast
Acid-fast
Acid-fastness is a physical property of certain bacteria, specifically their resistance to decolorization by acids during staining procedures.Acid-fast organisms are difficult to characterize using standard microbiological techniques Acid-fastness is a physical property of certain bacteria,...
rods (1-3 µm x 0.5-0.7 µm).
Colony characteristics
- Colonies are eugonic, rough and nonpigmented.
Physiology
- Colonies occur within 5 days at 30°C (optimum temperature, no growth at 45°C) on Löwenstein-Jensen medium and on Middlebrook 7H10 agar.
- The type strain is resistant to D-cycloserine, streptomycinStreptomycinStreptomycin is an antibiotic drug, the first of a class of drugs called aminoglycosides to be discovered, and was the first antibiotic remedy for tuberculosis. It is derived from the actinobacterium Streptomyces griseus. Streptomycin is a bactericidal antibiotic. Streptomycin cannot be given...
, isoniazidIsoniazidIsoniazid , also known as isonicotinylhydrazine , is an organic compound that is the first-line antituberculosis medication in prevention and treatment. It was first discovered in 1912, and later in 1951 it was found to be effective against tuberculosis by inhibiting its mycolic acid...
, rifampin, and thiacetazone - The type strain is susceptible to kanamycinKanamycinKanamycin sulfate is an aminoglycoside antibiotic, available in oral, intravenous, and intramuscular forms, and used to treat a wide variety of infections. Kanamycin is isolated from Streptomyces kanamyceticus.-Mechanism:...
, capreomycinCapreomycinCapreomycin is a peptide antibiotic, commonly grouped with the aminoglycosides, which is given in combination with other antibiotics for tuberculosis...
and high levels of isoniazidIsoniazidIsoniazid , also known as isonicotinylhydrazine , is an organic compound that is the first-line antituberculosis medication in prevention and treatment. It was first discovered in 1912, and later in 1951 it was found to be effective against tuberculosis by inhibiting its mycolic acid...
.
Differential characteristics
- Differentiation from all other mycobacterial species by its unusual mycolate pattern.
Type strain
First isolated from water samples, from soil and human sputum samples in Spain.Strain CR-21 = ATCC 51304 = CIP 103464 = DSM 44176 = JCM 12272.