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Myalgia
 
 
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Myalgia means "muscle
MUSCLE

MUSCLE is public domain, multiple sequence alignment software for protein and nucleotide sequences.MUSCLE is integrated into UGENE bioinformatics tool as a plugin....
 pain
Pain

Pain, in the sense of physical pain, is a typical sensory experience that may be described as the unpleasant awareness of a noxious stimulus or bodily harm....
" and is a symptom of many diseases and disorders. The most common causes are overuse or over-stretching of a muscle or group of muscles. Myalgia without a traumatic history is often due to viral infection
Virus

A virus is a Optical microscope#Limitations of light microscopes infectious agent that is unable to grow or reproduce outside a host cell . Viruses infect all cellular life....
s. Longer-term myalgias may be indicative of a metabolic myopathy
Metabolic myopathy

Metabolic myopathies are Myopathy that result from defects in biochemical metabolism that primarily affect muscle. They include:1- Glycogen storage diseases...
, some nutritional deficiencies or chronic fatigue syndrome
Chronic fatigue syndrome

Chronic fatigue syndrome is the most common name given to a poorly understood, variably debilitating disorder or disorders of uncertain etiology....
.

most common causes of myalgia are overuse, injury
Injury

Injury or bodily injury is damage or harm caused to the structure or Purpose of the body caused by an outside wiktionary:agent or force, which may be physical or chemical....
 or stress
Stress (medicine)

Stress is a biological term which refers to the consequences of the failure of a human or animal body to respond appropriately to emotional or body threats to the organism, whether actual or imagined....
. However, myalgia can also be caused by diseases, disorders, medications, as a response to vaccination
Vaccination

Vaccination is the administration of antigenic material to produce immunity to a disease. Vaccines can prevent or ameliorate the effects of infection by a pathogen....
 and withdrawal syndromes.






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Encyclopedia


Myalgia means "muscle
MUSCLE

MUSCLE is public domain, multiple sequence alignment software for protein and nucleotide sequences.MUSCLE is integrated into UGENE bioinformatics tool as a plugin....
 pain
Pain

Pain, in the sense of physical pain, is a typical sensory experience that may be described as the unpleasant awareness of a noxious stimulus or bodily harm....
" and is a symptom of many diseases and disorders. The most common causes are overuse or over-stretching of a muscle or group of muscles. Myalgia without a traumatic history is often due to viral infection
Virus

A virus is a Optical microscope#Limitations of light microscopes infectious agent that is unable to grow or reproduce outside a host cell . Viruses infect all cellular life....
s. Longer-term myalgias may be indicative of a metabolic myopathy
Metabolic myopathy

Metabolic myopathies are Myopathy that result from defects in biochemical metabolism that primarily affect muscle. They include:1- Glycogen storage diseases...
, some nutritional deficiencies or chronic fatigue syndrome
Chronic fatigue syndrome

Chronic fatigue syndrome is the most common name given to a poorly understood, variably debilitating disorder or disorders of uncertain etiology....
.

Causes

The most common causes of myalgia are overuse, injury
Injury

Injury or bodily injury is damage or harm caused to the structure or Purpose of the body caused by an outside wiktionary:agent or force, which may be physical or chemical....
 or stress
Stress (medicine)

Stress is a biological term which refers to the consequences of the failure of a human or animal body to respond appropriately to emotional or body threats to the organism, whether actual or imagined....
. However, myalgia can also be caused by diseases, disorders, medications, as a response to vaccination
Vaccination

Vaccination is the administration of antigenic material to produce immunity to a disease. Vaccines can prevent or ameliorate the effects of infection by a pathogen....
 and withdrawal syndromes. It is also a sign of acute rejection after heart transplant surgery.

Overuse

Overuse of a muscle is using it too much, too soon and/or too often. Examples are:
  • Repetitive strain injury
    Repetitive strain injury

    Repetitive strain injury , also known as Cumulative Trauma Disorder , occupational overuse syndrome, non-specific arm pain or work related upper limb disorder , is the most recent manifestation of illness concepts that link use of the arm to injury or disease....
    .


Injury

The most common causes of myalgia by injury
Injury

Injury or bodily injury is damage or harm caused to the structure or Purpose of the body caused by an outside wiktionary:agent or force, which may be physical or chemical....
 are: sprains and strain (injury)
Strain (injury)

A strain is an injury to a muscle in which the muscle fibers tear as a result of stretching. Strains are also colloquially known as pulled muscles....
.

Diseases/Disorders


Infectious
Acute Endocarditis
Endocarditis

Endocarditis is an inflammation of the inner layer of the heart, the endocardium. It usually involves the heart valves . Other structures which may be involved include the interventricular septum, the chordae tendinae, the mural endocardium, or even on intracardiac devices....
, African Tick Bite Fever, Bronchitis
Bronchitis

Bronchitis is an inflammation of the large bronchus in the lungs. It can progress to pneumonia. Acute bronchitis is usually caused by viruses or bacteria and may last several days or weeks....
, Chikungunya
Chikungunya

Chikungunya virus is an arbovirus, of the genus, Alphavirus, that is transmitted to humans by virus-carrying Aedes mosquitoes.or=de Lamballerie X, Leroy E, Charrel RN, Ttsetsarkin K, Higgs S, Gould EA...
, Common cold
Common cold

Acute viral rhinopharyngitis, or acute coryza, usually known as the common cold, is a highly contagious, virus infectious disease of the upper respiratory system, primarily caused by picornaviruses or coronaviruses....
, Community-acquired pneumonia
Community-acquired pneumonia

Community-acquired pneumonia is a disease in which individuals who have not recently been hospitalized develop an infection of the lungs . CAP is a common illness and can affect people of all ages....
, Coccidioidomycosis
Coccidioidomycosis

Coccidioidomycosis is a fungus disease caused by Coccidioides immitis or Coccidioides posadasii. It is endemic in certain parts of Arizona, California, Nevada, New Mexico, Texas, Utah and northwestern Mexico....
, Dengue fever
Dengue fever

Dengue fever and dengue hemorrhagic fever are acute fever tropical diseases, found in the tropics and Africa, and caused by four closely related virus serotypes of the genus Flavivirus, family Flaviviridae....
, Endemic typhus, HIV
HIV

Human immunodeficiency virus is a lentivirus that can lead to AIDS , a condition in humans in which the immune system begins to fail, leading to life-threatening opportunistic infections....
, Infectious mononucleosis
Infectious mononucleosis

EBV infectious mononucleosis is an infectious, viral disease which most commonly occurs in adolescents and young adults. It is characterized by fever, sore throat and fatigue , along with several other possible signs and symptoms....
, Influenza
Influenza

Influenza, commonly known as the flu, is an infectious disease that affects birds and mammals caused by RNA viruses of the biological family Orthomyxoviridae ....
, Legionellosis
Legionellosis

Legionellosis is an infectious disease caused by bacteria belonging to the genus Legionella. Over 90% of legionellosis cases are caused by Legionella pneumophila, a ubiquitous aquatic organism that thrives in warm environments ....
, Leptospirosis
Leptospirosis

Leptospirosis is a infectious disease zoonotic disease caused by spirochaetes of the genus Leptospira that affects humans and a wide range of animals, including mammals, birds, amphibians, and reptiles....
, Lyme disease
Lyme disease

Lyme disease, or borreliosis, is an emerging infectious disease caused by at least three species of bacteria belonging to the genus Borrelia....
, Malaria
Malaria

Malaria is a Vector -borne infectious disease caused by protozoan parasites. It is widespread in Tropics and subtropical regions, including parts of the Americas, Asia, and Africa....
, Marburg virus
Marburg virus

Marburg virus or simply Marburg is the common name for the the genus of viruses Marburgvirus, which contains one species Lake Victoria marburgvirus....
, Meningitis
Meningitis

Meningitis is a medical condition caused by inflammation of the protective membranes covering the brain and spinal cord, known collectively as the meninges....
, Monkeypox
Monkeypox

Monkeypox is a rare infectious disease caused by monkeypox virus. The disease was first identified in laboratory monkeys, giving it its name. The disease is most prevalent in Central Africa and West Africa, but an outbreak occurred also in the United States in 2003....
, Pharyngitis
Pharyngitis

Pharyngitis is an inflammation of the throat or pharynx. In most cases it is painful, and thus is often referred to as a sore throat. Inflammation of the tonsils and/or larynx occur simultaneously, which can make eating difficult or painful....
, Pneumonia
Pneumonia

Pneumonia is an Inflammation illness of the lung. Frequently, it is described as lung parenchyma/alveolus inflammation and abnormal alveolar filling with fluid ....
, Prostatitis
Prostatitis

Prostatitis is an inflammation of the prostate gland, in men. A prostatitis diagnosis is assigned at 8% of all urologist and 1% of all primary care physician visits in the United States....
, Psittacosis
Psittacosis

In medicine , psittacosis — also known as parrot disease, parrot fever, and ornithosis — is a zoonosis infectious diseases caused by a bacterium called Chlamydophila psittaci and contracted not only from parrots, such as macaws, cockatiels and budgerigars, but also from pigeons, sparrows, ducks, Chickens, gu...
, Q fever
Q fever

Q fever is a disease caused by infection with Coxiella burnetii, a bacterium that affects both humans and animals. This organism is uncommon but may be found in cow, sheep, goats and other domestic mammals, including cats and dogs....
, Rabies
Rabies

Rabies is a virus zoonotic neurotropic virus disease that causes acute encephalitis in mammals. It is most commonly caused by a bite from an infected animal, but occasionally by other forms of contact....
, Rift Valley fever
Rift Valley fever

Rift Valley Fever is a viral zoonosis causing fever. It is spread by the bite of infected mosquitoes, typically the Aedes or Culex genera. The disease is caused by the RVF virus , a member of the genus Phlebovirus ....
, Ross River Fever
Ross River Fever

Ross River Fever is a tropical disease infectious disease, often characterised by influenza-like illness and polyarthritis, caused by infection with the Ross River virus, a mosquito-borne Alphavirus endemic to Australia, Papua New Guinea and several islands in the South Pacific....
, Severe Acute Respiratory Syndrome (SARS)
Severe acute respiratory syndrome

Severe acute respiratory syndrome is a respiratory disease in humans which is caused by the SARS coronavirus . There has been one near pandemic to date, between November 2002 and July 2003, with 8,096 known infected cases and 774 deaths worldwide being listed in the World Health Organization's 21 April 2004 concluding report....
, Toxic shock syndrome
Toxic shock syndrome

Toxic shock syndrome is a very rare but potentially fatal illness caused by a Exotoxin. Different bacteriuml toxins may cause toxic shock syndrome, depending on the situation....
, Acute toxoplasmosis
Toxoplasmosis

Toxoplasmosis is a parasitic disease caused by the protozoan Toxoplasma gondii. The parasite infects most genera of warm-blooded animals, including humans, but the primary host is the Felidae....
 Trichinosis
Trichinosis

Trichinosis, also called trichinellosis, or trichiniasis, is a parasitic disease caused by eating raw or undercooked pork and wild game infected with the larvae of a species of roundworm Trichinella spiralis, commonly called the trichina worm....
, Typhoid fever
Typhoid fever

Typhoid fever, also known as enteric fever, or commonly just typhoid, is an illness caused by the bacterium Salmonella typhi. Common worldwide, it is transmitted by the ingestion of food or water contaminated with feces from an infected person....
, Upper respiratory tract infection
Upper respiratory tract infection

Upper respiratory tract infections, , are the illnesses caused by an acute infection which involves the upper respiratory tract: nose, Paranasal sinus, pharynx or larynx....
, Viral pneumonia
Viral pneumonia

Viral pneumonia is a pneumonia caused by a virus. Viruses are the most common cause of pneumonia in children....
, West Nile virus
West Nile virus

West Nile virus is a virus of the family Flaviviridae. Part of the Japanese encephalitis antigenic complex of viruses, it is found in both tropics and temperate regions....
.

Autoimmune
Multiple sclerosis
Multiple sclerosis

Multiple sclerosis is an autoimmune disease in which the immune system attacks the central nervous system, leading to demyelinating disease. Disease onset usually occurs in young adults, and it is more common in females....
, Myositis
Myositis

Myositis is a general term for inflammation of the muscles. Many such conditions are considered likely to be caused by autoimmune conditions, rather than directly due to infection It is also a documented side effect of statins....
, Lupus erythematosus
Lupus erythematosus

Lupus erythematosus is a connective tissue disease....
, Familial Mediterranean fever
Familial Mediterranean fever

Familial Mediterranean Fever is a genetic disorder inflammation disorder that affects groups of people originating from around the Mediterranean Sea ....
, Polyarteritis nodosa
Polyarteritis nodosa

Polyarteritis nodosa is a vasculitis of medium-sized arteries, which become swollen and damaged from attack by rogue immune cells. Polyarteritis nodosa is also called Adolph Kussmaul disease or Kussmaul-Rudolf Robert Meier disease....
, Devic's disease
Devic's disease

Devic's disease, also known as Devic's syndrome or neuromyelitis optica , is an autoimmune disease, inflammation disorder in which a person's own immune system attacks the optic nerves and spinal cord....
, Morphea
Morphea

Did you perhaps mean morphia?Morphea is a medical term for localized scleroderma. The disease involves isolated patches of hardened skin - there generally is no internal organ involvement....


Metabolic defect
Carnitine palmitoyltransferase II deficiency
Carnitine palmitoyltransferase II deficiency

Carnitine palmitoyltransferase II deficiency is a metabolic disorder characterized by an enzymatic defect that prevents long-chain fatty acids from being transported into the mitochondria for utilization as an energy source....
, Conn's syndrome
Conn's syndrome

Primary aldosteronism, also known as primary hyperaldosteronism, is characterized by the overproduction of the mineralocorticoid hormone aldosterone by the adrenal glands....
, Adrenal insufficiency
Adrenal insufficiency

Adrenal insufficiency is a condition in which the adrenal glands, located above the kidneys, do not produce adequate amounts of steroid hormones , primarily cortisol, but may also include impaired aldosterone production which regulates sodium, potassium and water retention....


Other
Chronic fatigue syndrome
Chronic fatigue syndrome

Chronic fatigue syndrome is the most common name given to a poorly understood, variably debilitating disorder or disorders of uncertain etiology....
, Hypokalemia
Hypokalemia

Hypokalemia refers to the condition in which the concentration of potassium in the blood is low. The prefix hypo- means low . Kal refers to kalium, the Neo-Latin for potassium, and -emia means "in the blood."...
, Exercise intolerance
Exercise intolerance

Exercise intolerance is a condition where the patient is unable to do physical exercise at the level or for the duration that would be expected of someone in his or her general physical condition, or experiences unusually severe post-exercise pain, fatigue , or other negative effects....
, Mastocytosis
Mastocytosis

Mastocytosis is a group of rare disease disorders of both children and adults caused by the presence of too many mast cells and CD34+ mast cell precursors in a person's body....
, Peripheral neuropathy
Peripheral neuropathy

Peripheral neuropathy is the term for damage to nerves of the peripheral nervous system, which may be caused either by diseases of the nerve or from the Adverse effect of systemic illness....
, Eosinophilia myalgia syndrome, Fibromyalgia
Fibromyalgia

Fibromyalgia , meaning muscle and connective tissue pain , is a disorder classified by the presence of chronic widespread pain and a heightened and painful response to gentle Somatosensory system ....
, Barcoo Fever
Barcoo Fever

Barcoo Fever is an illness once common in the Outback but is now virtually unknown. It was characterised by nausea and vomiting exacerbated by the sight or smell of food and, unlike the usual gastro-intestinal infections, by constipation rather than diarrhoea....
, Herpes, Delayed onset muscle soreness
Delayed onset muscle soreness

Delayed onset muscle soreness , also sometimes called muscle fever, is the pain or discomfort often felt 24 to 72 hours after exercising and subsides generally within 2 to 3 days....
, AIDS
AIDS

Acquired immune deficiency syndrome or acquired immunodeficiency syndrome is a disease of the human immune system caused by the HIV ....
, HIV
HIV

Human immunodeficiency virus is a lentivirus that can lead to AIDS , a condition in humans in which the immune system begins to fail, leading to life-threatening opportunistic infections....


Medications

Acrylamide
Acrylamide

The chemical compound acrylamide has the chemical formula Carbon3Hydrogen5NitrogenOxygen. Its IUPAC name is 2-propenamide....
, colesevelam
Colesevelam

Colesevelam is a bile acid sequestrant administered orally. It is developed by Genzyme and marketed in the US by Daiichi Sankyo under the brand name WelChol and elsewhere by Genzyme under the tradename Cholestagel....
, darbepoetin, ezetimibe
Ezetimibe

Ezetimibe is an anti-hyperlipidemic medication which is used to lower cholesterol levels. It acts by decreasing cholesterol absorption in the intestine....
, gardasil
Gardasil

Gardasil , also known as Gardisil or Silgard, is a HPV vaccine .Gardasil is designed to prevent infection with human papillomavirus types 16, 18, 6, and 11....
, ibandronate sodium, imiquimod
Imiquimod

Imiquimod is a prescription medication that acts as an immune response modifier. It is marketed by MEDA AB, Graceway Pharmaceuticals and iNova Pharmaceuticals under the trade name Aldara and by Mochida as Beselna....
, interferon
Interferon

Interferons are natural proteins produced by the cells of the immune system of most vertebrates in response to challenges by foreign agents such as viruses, parasites and tumor cells....
s,isotretinoin
Isotretinoin

Isotretinoin is a medication used for the treatment of moderate to severe Acne vulgaris. It is sometimes used as a chemotherapy medication for prevention and treatment of certain skin cancers....
, procainamide
Procainamide

Procainamide is a pharmaceutical antiarrhythmic agent used for the medicine Pharmacotherapy of cardiac arrhythmias, classified by the Vaughan Williams classification system as class Ia....
, quinupristin/dalfopristin
Quinupristin/dalfopristin

Quinupristin/dalfopristin is a combination of two antibiotics used to treat infections by staphylococcus and by vancomycin-resistant Enterococcus....
, statins, sumatriptan
Sumatriptan

Sumatriptan is a triptan drug including a sulfonamide group for the treatment of migraine headaches. It is marketed and manufactured by GlaxoSmithKline....
, tiotropium
Tiotropium

Tiotropium is a long-acting, 24 hour, anticholinergic bronchodilator used in the management of chronic obstructive pulmonary disease . Tiotropium bromide capsules for inhalation are co-marketed by Boehringer-Ingelheim and Pfizer Inc....
, vardenafil
Vardenafil

Vardenafil is a PDE5 inhibitor used for treating impotence that is sold under the trade name Levitra , , ....
, zolmitriptan
Zolmitriptan

Zolmitriptan is an selective serotonin receptor agonist of the 1B and 1D subtypes. It is a triptan, used in the acute treatment of migraine attacks with or without aura and cluster headaches....
.

Withdrawal Syndromes

Sudden cessation of opioids, barbiturates, benzodiazepines, or alcohol
Alcohol

In chemistry, an alcohol is any organic compound in which a hydroxyl Functional group is bound to a carbon atom of an alkyl or substituted alkyl group....
 can induce myalgia.

See also

  • Delayed onset muscle soreness
    Delayed onset muscle soreness

    Delayed onset muscle soreness , also sometimes called muscle fever, is the pain or discomfort often felt 24 to 72 hours after exercising and subsides generally within 2 to 3 days....
  • Myopathy
    Myopathy

    In medicine, a myopathy is a muscular disease in which the muscle fibers do not function for any one of many reasons, resulting in muscular weakness....
  • Myelitis
    Myelitis

    Myelitis is a disease involving inflammation of the spinal cord, which disrupts central nervous system functions linking the brain and limbs....


External links

  • a more comprehensive list