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Multinucleate

 

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Multinucleate



 
 
Multinucleate (also multinucleated, coenocytic) cells have more than one nucleus
Cell nucleus

In cell biology, the nucleus , also sometimes referred to as the "control center", is a membrane-enclosed organelle found in all eukaryote cell ....
 per cell
Cell (biology)

The cell is the structural and functional unit of all known Life organisms. It is the smallest unit of an organism that is classified as living, and is often called the building bricks of life....
, which is the result of nuclear division not being followed by cytokinesis
Cytokinesis

Cytokinesis is the process where the cytoplasm of a single eukaryotic cell is divided to form two daughter cells. It usually initiates during the late stages of mitosis, and sometimes meiosis, splitting a binucleate cell in two, to ensure that chromosome number is maintained from one generation to the next....
. As a consequence, multiple nuclei share one common cytoplasm
Cytoplasm

The cytoplasm is the part of a Cell that is enclosed within the plasma membrane. In eukaryote cells the cytoplasm contains organelles, such as mitochondrion, that are filled with liquid kept separate from the rest of the cytoplasm by biological membranes....
. This can be the consequence of a disturbed cell cycle control (e.g. in metastazing tumor
Tumor

A tumor or tumour is the name for a swelling or lesion formed by an abnormal growth of cells . Tumor is not synonymous with cancer. A tumor can be Benign neoplasm, Carcinoma in situ or malignant, whereas cancer is by definition malignant....
 cells and certain mutants of S. cerevisiae) but also commonly occurs naturally (e.g.






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Multinucleate (also multinucleated, coenocytic) cells have more than one nucleus
Cell nucleus

In cell biology, the nucleus , also sometimes referred to as the "control center", is a membrane-enclosed organelle found in all eukaryote cell ....
 per cell
Cell (biology)

The cell is the structural and functional unit of all known Life organisms. It is the smallest unit of an organism that is classified as living, and is often called the building bricks of life....
, which is the result of nuclear division not being followed by cytokinesis
Cytokinesis

Cytokinesis is the process where the cytoplasm of a single eukaryotic cell is divided to form two daughter cells. It usually initiates during the late stages of mitosis, and sometimes meiosis, splitting a binucleate cell in two, to ensure that chromosome number is maintained from one generation to the next....
. As a consequence, multiple nuclei share one common cytoplasm
Cytoplasm

The cytoplasm is the part of a Cell that is enclosed within the plasma membrane. In eukaryote cells the cytoplasm contains organelles, such as mitochondrion, that are filled with liquid kept separate from the rest of the cytoplasm by biological membranes....
. This can be the consequence of a disturbed cell cycle control (e.g. in metastazing tumor
Tumor

A tumor or tumour is the name for a swelling or lesion formed by an abnormal growth of cells . Tumor is not synonymous with cancer. A tumor can be Benign neoplasm, Carcinoma in situ or malignant, whereas cancer is by definition malignant....
 cells and certain mutants of S. cerevisiae) but also commonly occurs naturally (e.g. in filamentous fungi, Proteus mirabilis
Proteus mirabilis

Proteus mirabilis is a Gram-negative, facultatively Anaerobic organism bacterium. It shows swarming motility, and urease activity. P. mirabilis causes 90% of all 'Proteus' infections in humans....
 swarmer cells, cells of the musculoskeletal and blood systems of mammals).

In some cases these cells are produced from specialized cell cycles in which nuclear division occurs without cell division leading to large syncytia. For fungi, multinucleate cells may extend over hundreds of meters so that different regions of a single cell experience dramatically different microenvironments.

Mitosis
Mitosis

Mitosis is the process in which a eukaryotic cell separates the chromosomes in its cell nucleus, into two identical sets in two daughter nuclei....
 in multinucleate cells can occur either in a coordinated, synchronous manner where all nuclei divide simultaneously or asynchronously where individual nuclei divide independently in time and space.