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Macule
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A macule is a change in skin color, without elevation or depression and, therefore, nonpalpable, well or ill-defined, variously sized but, by convention, less than one centimeter in diameter at the widest point.[With regard to the quote "...by convention, less than one centimeter in diameter at the widest point," depending on which text is referenced, some authors state the cutoff between a macule and a patch as 0.5cm, not 1cm, while others state an entirely different measurement.]

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Encyclopedia
A macule is a change in skin color, without elevation or depression and, therefore, nonpalpable, well or ill-defined, variously sized but, by convention, less than one centimeter in diameter at the widest point.[With regard to the quote "...by convention, less than one centimeter in diameter at the widest point," depending on which text is referenced, some authors state the cutoff between a macule and a patch as 0.5cm, not 1cm, while others state an entirely different measurement. Therefore, for this article, the 1cm cutoff is used which is discussed in Andrews' Diseases of the Skin: Clinical Dermatology (see references), a work considered by some dermatologists as an authority on this subject matter.] This skin lesion is recognizable due to the color difference compared with the surrounding normal skin, and may be of any color, white, blue, or red for example. Macules may be the result of hyperpigmentation, hypopigmentation, vascular abnormalities, capillary dilatation (erythema), or purpura (extravasated red blood cells). Diseases of the skin that present with maculae include, but are not limited to, vitiligo, melasma, and junctional nevi.
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