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Lupus erythematosus

 

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Lupus erythematosus



 
 
Lupus erythematosus is a connective tissue disease
Connective tissue disease

A connective tissue disease is any disease that has the connective tissues of the body as a target of pathology. Connective tissue is any type of biological tissue with an extensive extracellular matrix that supports, binds together, and protects organ s....
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Encyclopedia


Lupus erythematosus is a connective tissue disease
Connective tissue disease

A connective tissue disease is any disease that has the connective tissues of the body as a target of pathology. Connective tissue is any type of biological tissue with an extensive extracellular matrix that supports, binds together, and protects organ s....
.

Types

Lupus erythematosus may manifest as a systemic disease
Systemic disease

A systemic disease is one that affects a number of organs and tissues, or affects the body as a whole Although most medical conditions will eventually involve multiple Organ in advanced stage , diseases where multiple organ involvement is at presentation or in early stage are considered above....
 or in purely cutaneous forms, categorized into the following types:

  • Chronic cutaneous lupus erythematosus
    • Discoid lupus erythematosus
      Discoid lupus erythematosus

      Discoid lupus erythematosus is an uncommon autoimmune disease of the Stratum germinativum of the skin. It occurs in humans and cats, more frequently occurring in dogs....
      • Childhood discoid lupus erythematosus
        Childhood discoid lupus erythematosus

        Childhood discoid lupus erythematosus lacks a female predominace, low frequency of photosensitivity, and higher progression to systemic lupus erythematosus, but in most other respects, the clinical presentation and course is similar to those in adults....
      • Generalized discoid lupus erythematosus
        Generalized discoid lupus erythematosus

        Generalized discoid lupus erythematosus is less common than localized discoid lupus erythematosus, with all degrees of severity being encountered, most often affecting the thorax and upper exemities in addition to the head and neck....
      • Localized discoid lupus erythematosus
        Localized discoid lupus erythematosus

        Localized discoid lupus erythematosus typically presents with lesions localized above the neck, with favored sites being the scalp, bridge of nose, malar areas, lower lip, and ears....
    • Chilblain lupus erythematosus
      Chilblain lupus erythematosus

      Chilblain lupus erythematosus is a chronic, unremitting form of lupus erythematosus with the fingertips, rims of ears, claves, and heels affected, especially in women....
       (Hutchinson)
    • Lupus erythematosus-lichen planus overlap syndrome
      Lupus erythematosus-lichen planus overlap syndrome

      Lupus erythematosus-lichen planus overlap syndrome is a true overlap syndrome with features of both lupus erythematosus and lichen planus, with skin lesions usually large, atropic, hypopigmented, red or pink patches and plaques....
    • Lupus erythematosus panniculitis
      Lupus erythematosus panniculitis

      Lupus erythematosus panniculitis presents with subcutaneous nodules that are commonly firm, sharply defined, and nontender....
       (Lupus erythematosus profundus)
    • Subacute cutaneous lupus erythematosus
      Subacute cutaneous lupus erythematosus

      Subacute cutaneous lupus erythematosus is a clinically distinct subset of cases of lupus erythematosus that is most often present in white women aged 15 to 40, consisting of skin lesions that are scaly and evolve as polycylic annular lesions or psoriasiform plaques....
    • Tumid lupus erythematosus
      Tumid lupus erythematosus

      Tumid lupus erythematosus is a rare, but distinctive entity in which patients present with edematous erythematous plaques, usually on the trunk....
    • Verrucous lupus erythematosus
      Verrucous lupus erythematosus

      Verrucous lupus erythematosus presents with non-puritic papulonodular lesions on the arms and hands, resembling keratoacanthoma or hypertropic lichen planus....
       (Hypertrophic
      Hypertrophic

      Hypertrophic may refer to:* Excessive accumulation* A classification of excessive amounts of nutrients in a body of water* The medical terminology where an increased size of an organ is observed, See Organ hypertrophy....
       lupus erythematosus)
  • Complement deficiency syndromes
    Complement deficiency syndromes

    Complement deficiency syndromes are often associated with lupus erythematosus-like conditions, and although deficiency of many complement components may cause LE-like conditions, they are most commonly caused by C2 and C4 deficiencies....
  • Drug-induced lupus erythematosus
    Drug-induced lupus erythematosus

    Drug-induced lupus erythematosus is an autoimmune disorder, similar to systemic lupus erythematosus , which is induced by chronic use of certain drugs....
  • Neonatal lupus erythematosus
    Neonatal lupus erythematosus

    Neonatal lupus erythematosus presents in infants, most often girls, born to mothers who carry the Ro/SSA antibody. The infants have no skin lesions at birth, but develop them during the first weeks of life....
  • Systemic lupus erythematosus
    Systemic lupus erythematosus

    Systemic lupus erythematosus is a chronic Autoimmunity connective tissue disease that can affect any part of the body. As occurs in other autoimmune diseases, the immune system attacks the body?s cells and tissue, resulting in inflammation and tissue damage....


See also

  • Lupus band test
    Lupus band test

    Lupus band test is done upon skin biopsy, with immunofluorescence staining, in which, if positive, IgG and complement depositions are found at the dermal-epidermal junction....
  • Cicatricial alopecia
    Cicatricial alopecia

    Cicatricial alopecia presents clinically with the effacement/scarring of follicular orifices, always in a patchy or focal distribution....
  • List of skin-related conditions
    List of skin-related conditions

    This is list of skin-related conditions of or affecting the human integumentary system....
  • Skin disease
  • Skin lesions


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