List of Spider-Man enemies
Encyclopedia
Spider-Man
Spider-Man
Spider-Man is a fictional Marvel Comics superhero. The character was created by writer-editor Stan Lee and writer-artist Steve Ditko. He first appeared in Amazing Fantasy #15...

has one of the best-known rogues galleries
Rogues gallery
A rogues gallery is a police collection of pictures or photographs of criminals and suspects kept for identification purposes...

 in comics, in part because he has been the featured character in more individual titles (Amazing Spider-Man, Spectacular Spider-Man, Marvel Team-Up, Web of Spider-Man, Friendly Neighborhood Spider-Man, and others, many of which were published simultaneously for years) than any other comic book superhero except for Superman
Superman
Superman is a fictional comic book superhero appearing in publications by DC Comics, widely considered to be an American cultural icon. Created by American writer Jerry Siegel and Canadian-born American artist Joe Shuster in 1932 while both were living in Cleveland, Ohio, and sold to Detective...

 and Batman
Batman
Batman is a fictional character created by the artist Bob Kane and writer Bill Finger. A comic book superhero, Batman first appeared in Detective Comics #27 , and since then has appeared primarily in publications by DC Comics...

, giving him a large number of published stories in which to fight a proportionately large number of villains. As with Spider-Man, the majority of these villains' powers originate with scientific accidents or the misuse of scientific technology, tend to have animal-themed costumes or powers, and are nearly all male. At times these villains have formed groups such as the Sinister Six
Sinister Six
The Sinister Six are a group of supervillains in the Marvel Comics universe, drawn from Spider-Man's rogues gallery. The original incarnation of the group was organized by Doctor Octopus, and first appeared in The Amazing Spider-Man Annual #1 ....

 to oppose Spider-Man.
Spider-Man has one of the largest rouges galleries, alongside Batman and The Flash
Flash (comics)
The Flash is a name shared by several fictional comic book superheroes from the DC Comics universe. Created by writer Gardner Fox and artist Harry Lampert, the original Flash first appeared in Flash Comics #1 ....

.

Central Rogues gallery

Spider-Man's most renowned rogues include (in alphabetical order):
Villain First appearance Description
Alistair Smythe
Alistair Smythe
Alistair Smythe is a comic book supervillain, owned by Marvel Comics and existing in that company's Marvel Universe. He was one of the main foes of Spider-Man...

Amazing Spider-Man Annual #19 (December 1985) Alistair Smythe was destined to finish what his father Spencer Smythe began as well as avenging his father's death who be blames on Spider-Man and J. Jonah Jameson. He created new Spider-Slayer
Spider-Slayer
The Spider-Slayers are a series of fictional robots in the Marvel Comics universe that were specifically designed to hunt down, capture, and/or kill Spider-Man.-Fictional character biography:...

s, and became one himself dubbing himself now as "the Spider-Slayer". He is also responsible for directly killing Marla Jameson, the wife of J. Jonah Jameson.
Beetle
Beetle (comics)
Abner Ronald Jenkins is a fictional character in the Marvel Comics universe.-Publication history:...

Strange Tales #123 (August 1964) Abner Jenkins was a master mechanic at an aircraft parts factory who became dissatisfied with his boring, low paying job. Using his considerable mechanical knowledge, Jenkins built an armor-plated, strength-augmenting suit, a pair of gravity-defying wings, suction-fingered gloves, and a cybernetic control helmet. Calling himself the Beetle, Jenkins decided to use his battle-suit for fame, wealth, and adventure.
Deadly Foes of Spider-Man #1 (May 1991) Leila Davis
Leila Davis
Leila Davis is a fictional character, a comic book supervillainess and later costumed hero in the Marvel Comics universe. She first went by the name Hardshell and later as the second Beetle. She was primarily an enemy of Spider-Man and the original Beetle.-Fictional character biography:Leila is at...

took over the identity of the Beetle
Beetle (comics)
Abner Ronald Jenkins is a fictional character in the Marvel Comics universe.-Publication history:...

 until being killed by Graviton
Graviton (comics)
Graviton is a fictional character that appears in comic books published by Marvel Comics. The character first appears in Avengers #158 and was created by Jim Shooter and Sal Buscema....

.
Boomerang
Boomerang (comics)
Boomerang is a fictional character, a supervillain appearing in the Marvel Comics universe and first appeared in Tales to Astonish #81....

 
Tales To Astonish #81 (July 1966) Fred Myers has no superhuman powers, but he has the strength, agility and endurance of a professional athlete from his days as a baseball player. He can throw projectiles with nearly unerring accuracy, and his aim is nearly the peak of what a non-superpowered human can accomplish.

Boomerang's most dangerous assets are, naturally, his arsenal of specialized boomerangs. He has modified and improved on them over the years, but the most common ones are exploding boomerangs (with enough explosive power to destroy an automobile), razor-bladed boomerangs, and boomerangs that release large doses of tear gas to disable a target.
Burglar
Burglar (comics)
The Burglar is a fictional character in the Marvel Universe, left unnamed in most of his appearances. He is best known as the first criminal faced by Spider-Man, and as the killer of the hero's uncle and surrogate father figure, Ben Parker. The Burglar first appeared in Amazing Fantasy #15 .The...

 
Amazing Fantasy #15 (August 1962) The man who murdered Peter Parker's beloved uncle, Ben Parker. Little is known about this common criminal except that his name was Dennis Carradine and that he had a daughter named Jessica Carradine who became a love interest of Spider-clone, Ben Reilly.
Carnage
Carnage (comics)
Carnage is a fictional character, a supervillain in the . The character first appears in The Amazing Spider-Man #344 , and was created by writer David Michelinie and artist Mark Bagley. The character is frequently depicted as an enemy of Spider-Man...

 
Amazing Spider-Man #360 (April 1992) Carnage was the combination of a symbiote spawn
Spawn (biology)
Spawn refers to the eggs and sperm released or deposited, usually into water, by aquatic animals. As a verb, spawn refers to the process of releasing the eggs and sperm, also called spawning...

ed from the original Venom symbiote and a crazed serial killer, and former cell mate of Eddie Brock, Cletus Kasady. He thrived on murder and chaos and was many times stronger than Spider-Man. After nearly being killed by the Sentry
Sentry (Robert Reynolds)
The Sentry is a fictional character in the . The character first appears in The Sentry #1 and was created by Paul Jenkins and Jae Lee, with uncredited conceptual contributions by Rick Veitch.-Creation:...

, he was brought back by Industrialist Michael Hall, in a bid to use the Carnage symbiote to create an army of super-soldiers.
Chameleon
Chameleon (comics)
The Chameleon is a fictional character that appears in comic books published by Marvel Comics. The character first appears in The Amazing Spider-Man #1 , and was created by writer Stan Lee and artist Steve Ditko; the Chameleon is the first member of Spider-Man's rogues' gallery, based on issue...

 
Amazing Spider-Man #1 (March 1963) Dmitri Smerdyakov was a Russia
Russia
Russia or , officially known as both Russia and the Russian Federation , is a country in northern Eurasia. It is a federal semi-presidential republic, comprising 83 federal subjects...

n spy with a knack for disguises. He was the very first colorful supervillain Spidey has ever faced and was later revealed as the half-brother of Kraven the Hunter. Chameleon was employed by the Green Goblin to execute the cruel plan for creating Life Model Decoys of Peter's parents.
Doctor Octopus
Doctor Octopus
Doctor Octopus is a fictional character, a supervillain that appears in comic books published by Marvel Comics since 1963. A highly intelligent mad scientist, Doctor Octopus is one of Spider-Man's greatest foes...

Amazing Spider-Man #3 (July 1963) Dr. Otto Octavius is a respected scientist, one of the world's foremost experts in radiation who used four mechanical arms in his experiments, which bonded with his nervous system after an explosion becoming Doctor Octopus. He combines physical power with mad genius and is a founding member and leader of the Sinister Six
Sinister Six
The Sinister Six are a group of supervillains in the Marvel Comics universe, drawn from Spider-Man's rogues gallery. The original incarnation of the group was organized by Doctor Octopus, and first appeared in The Amazing Spider-Man Annual #1 ....

. After suffering from severe head trauma from battles with his super-powered foes, Doc Ock recently encased himself in a life support suit where he now relies on eight mechanical arms for mobility. He currently leads the Big Time version of the Sinister Six.
Amazing Spider-Man #406 (October 1995) During the Clone Saga, Dr. Otto Octavius (Doctor Octopus) is killed by Kaine and is replaced not long after by Carolyn Trainer
Lady Octopus
Lady Octopus , is a fictional character, a supervillainess in the Marvel Universe. Her first appearance was in Amazing Spider-Man #406 . She was created by J. M. DeMatteis and Angel Medina.-Fictional character biography:During the Clone Saga, Dr...

, daughter of Seward Trainer and adoring student of Octavius. She obtains a set of four tentacles identical to Octavius' and made use of a personal force-field that kept anything from hitting her. She took the name Doctor Octopus in honor of her beloved instructor but is later known as Lady Octopus
Electro  Amazing Spider-Man #9 (February 1964) An emotionally stunted man with an inferiority complex, Maxwell Dillon is struck by lightning while working on power lines and discovers that he has a supernatural control over electricity (he has become an evil
Evil
Evil is the violation of, or intent to violate, some moral code. Evil is usually seen as the dualistic opposite of good. Definitions of evil vary along with analysis of its root motive causes, however general actions commonly considered evil include: conscious and deliberate wrongdoing,...

 electrician
Electrician
An electrician is a tradesman specializing in electrical wiring of buildings, stationary machines and related equipment. Electricians may be employed in the installation of new electrical components or the maintenance and repair of existing electrical infrastructure. Electricians may also...

) Donning a green and yellow lightning themed costume, he goes on to battle Spider-Man numerous times.
Green Goblin
Green Goblin
The Green Goblin is a fictional character, a supervillain who appears in the comic books published by Marvel Comics. The character was created by writer Stan Lee and artist Steve Ditko, and first appeared in The Amazing Spider-Man #14 ....

Amazing Spider-Man #14 (July 1964) Originally a normal scientist and ambitious businessman, Norman Osborn uses an experimental formula which explodes, but gives him superpowers and also drives him insane. When Spider-Man thwarts his plans to take over as crime boss of New York City, he dedicates himself to utterly destroying Spider-Man's life. He is the first supervillain to discover Spider-Man's secret identity. Their mutual animosity becomes personal when Osborn kills Gwen Stacy
Gwen Stacy
Gwendolyn "Gwen" Stacy appears as a supporting character in Marvel Comics' Spider-Man series. Created by writer Stan Lee and artist Steve Ditko, she first appeared in The Amazing Spider-Man #31 ....

, Parker's long-time girlfriend and first true love. He is apparently killed by his own glider, but the formula allows him to heal. He is generally acknowledged to be Spider-Man's arch-nemesis and worst enemy, and also is responsible for the murder of Ben Reilly
Ben Reilly
Benjamin "Ben" Reilly is a fictional character in the . He is a clone of Peter Parker , and is prominent in the "Clone Saga" story arc...

, the disappearance of Peter Parker's infant daughter, his son Harry's spiral into madness and eventual death, and masterminding the entire Clone Saga
Clone Saga
The Clone Saga or Spider-Clone Saga was a major story arc in Marvel Comics which ran from 1994 to 1996 involving many clones of Spider-Man.The story is considered to be one of the most controversial Spider-Man stories ever told...

. Some of these events were changed from the 'One more Day' storyline.
Amazing Spider-Man #136 (September 1974) Harry Osborn
Harry Osborn
Harry Osborn is a fictional character, a supporting character of Spider-Man in the . In addition to being Peter Parker's best friend, Harry was the second Green Goblin and is the son of Norman Osborn...

, Norman's son and Peter Parker's best friend, eventually dons his father's old costume and continues his mission of hate against Spider-Man after his father's apparent death.
Amazing Spider-Man #175 (December 1977) Harry's therapist Bart Hamilton also dons the costume temporarily until he dies.
Hammerhead
Hammerhead (comics)
Hammerhead is a fictional character, a supervillain that has appeared in various comic book series published by Marvel Comics. He is primarily an enemy of Spider-Man and a member of organized crime who exists in Marvel's main shared universe, known as the Marvel Universe...

 
Amazing Spider-Man #113 (1972) Hammerhead is a member of organized crime and is closely associated with the Maggia
Maggia (comics)
The Maggia is a fictional international crime syndicate that has appeared in various comic book series published by Marvel Comics. The organization exists in Marvel's main shared universe, known as the Marvel Universe...

 crime family. Hammerhead distinguishes himself from other villains in that he dresses up and acts like a gangster from the 1920s. Due to an injury he suffers in which his skull is reinforced with metal, his head has a flat shape to it. Was upgraded by Mister Negative
Mister Negative
Mister Negative is a fictional comic book supervillain, appearing in books published by Marvel Comics, usually as an enemy of Spider-Man and the Punisher...

 with an adamatium skeleton in exchange for being his enforcer.
Hobgoblin
Hobgoblin (comics)
The Hobgoblin is the alias of several fictional characters that appears in comic books published by Marvel Comics. The first and best-known Hobgoblin is Roderick Kingsley. He first appeared in The Amazing Spider-Man #238, and was created by Roger Stern and John Romita, Sr...

Amazing Spider-Man #238 (March 1983) A millionaire fashion designer and criminal named Roderick Kingsley acquires the Green Goblin's weaponry and uses them to further his own ambitions after the Goblin's seeming death during a battle with Spider-Man. He modifies Osborn's original formula to give himself superhuman strength without becoming insane. He was responsible for the deaths of Donovan, Macendale, and Leeds, who all assumed the Hobgoblin mantle to remove suspicions of Kingsley's involvement with the Hobgoblin.
Amazing Spider-Man #238 (September 1983) Arnold Donovan is a petty thug in the employ of Kingsley who briefly became the Hobgoblin after he was exposed to Norman Osborn's Goblin formula.
Marvel Team-Up #138 (February 1984) Kingsley later brainwashes Ned Leeds
Ned Leeds
Ned Leeds is a comic book character in the Marvel Comics universe, part of the supporting cast of Spider-Man, first introduced in 1964 in The Amazing Spider-Man #18, by Stan Lee and Steve Ditko...

, a reporter working for the Daily Bugle
Daily Bugle
The Daily Bugle is a fictional New York City newspaper that is a regular fixture in the Marvel Universe, most prominently in Spider-Man comic titles and their derivative media...

, to act as a stand in on many occasions and fool the underworld into thinking that Leeds is the Hobgoblin.
Amazing Spider-Man #289 (June 1987) Jason Macendale
Jason Macendale
Jason Philip Macendale, Jr. is a fictional character that appears in comic books published by Marvel Comics. The character first appears in Machine Man #19 , and was created by writer Tom DeFalco and artist Steve Ditko....

also uses the Hobgoblin identity for a time before being killed by the original Hobgoblin, Roderick Kingsley.
Amazing Spider-Man #649 (January 2011) Phil Urich
Phil Urich
Philip Benjamin "Phil" Urich is a Marvel Comics character whose first appearance was in Web of Spider-Man #125. He once was the second person to use the Green Goblin identity as a superhero instead of a supervillain...

Phil Urich, who was previously retired from being the superhero version of the Green Goblin, became romantically interested in reporter Norah Winters. In order to impress Norah, he breaks into one of Norman Osborn's lairs where he encounters the original Hobgoblin, Roderick Kingsley who he kills in self-defense and takes on the Hobgoblin mantle. He partners with the Kingpin as one of his top agents while as Urich is employed for the Daily Bugle and uses a robotic flying camera to capture the Hobgoblin's activities that he sells to the Bugle, similar to Peter's approach to capturing photos of himself as Spider-Man.
Hydro-Man
Hydro-Man
Hydro-Man, also spelled Hydro Man , is a fictional character that appears in the comic books published by Marvel Comics...

 
Amazing Spider-Man #212 (January 1981) Morris Bench works on a cargo ship until an accident transforms him into a being of pigmented water, able to control his own liquid body. He has since been a frequent antagonist of Spider-Man and an occasional ally/enemy of the Sandman whom he once accidentally merged with and became a mud monster.
Jackal
Jackal (Marvel Comics)
The Jackal is a fictional character that appears in comic books published by Marvel Comics. The character first appears in The Amazing Spider-Man #129 , and was created by writer Gerry Conway and artist Ross Andru. In The Amazing Spider-Man #148 The Jackal is a fictional character that appears in...

 
Amazing Spider-Man #129 (February 1974) Dr. Miles Warren is an Empire State University
Empire State University
Empire State University is a fictional university in the Marvel Comics Universe, a mixture of New York University and Columbia University . It is located somewhere in New York City, in Greenwich Village near the site of New York University...

 biology professor who becomes infatuated with Peter Parker's girlfriend, Gwen Stacy. After she dies during a battle between Spider-Man and the Green Goblin, Warren becomes a demented geneticist and clones both Gwen Stacy and Peter Parker. He gains enhanced strength and agility by combining the genetic material of an actual jackal with his own. He fancies to genetic tampering of Spider-Man DNA which first results in the Clone Saga
Clone Saga
The Clone Saga or Spider-Clone Saga was a major story arc in Marvel Comics which ran from 1994 to 1996 involving many clones of Spider-Man.The story is considered to be one of the most controversial Spider-Man stories ever told...

 and the later infestation of Spider-Island where millions of New Yorkers develop manifestations of Spider-Man's radioactive powers.
Kaine
Kaine
Kaine is a fictional character, a Marvel Comics supervillain and antihero who serves as both an ally and an enemy of Spider-Man. He first appeared in Web of Spider-Man #119, and is the Jackal's first failed attempt at cloning Peter Parker...

 
Web of Spider-Man #119 (December 1994) Kaine was the first clone of Peter Parker created by Professor Miles Warren who also doubles as the Jackal with only one genetic flaw: he is slowly degenerating due to clone degeneration. His Spider-sense is altered to precognitive see fateful events in the future. His fate was met at the hands of the Kravinoff family, unknowing to Kravinoffs, was the man in the Spider-Man costume, which resulted in the resurrection of Kraven the Hunter during Grim Hunt.
Kingpin
Kingpin (comics)
The Kingpin is a fictional character, a supervillain in the . Kingpin is one of the most feared and powerful crime lords in the Marvel Universe. The character is a major adversary of Daredevil, the Punisher, and Spider-Man...

 
Amazing Spider-Man #50 (July 1967) Wilson Fisk is the most powerful crime boss in the New York City criminal underworld.
Kraven the Hunter
Kraven the Hunter
Kraven the Hunter is a fictional character, a supervillain and enemy of Spider-Man appearing in comic books published by Marvel Comics. Kraven's name is Sergei Kravinoff. He also appears as Xraven, with white-grey skin and red eyes, possessing the powers of X-Men. He is the half-brother of Dmitri...

Amazing Spider-Man #15 (August 1964) Perhaps the most respected big game hunter in the business, Sergei Kravinoff
Kraven the Hunter
Kraven the Hunter is a fictional character, a supervillain and enemy of Spider-Man appearing in comic books published by Marvel Comics. Kraven's name is Sergei Kravinoff. He also appears as Xraven, with white-grey skin and red eyes, possessing the powers of X-Men. He is the half-brother of Dmitri...

eventually set on a quest to capture the most elusive prey there is - Spider-Man. He initially committed suicide after believing he defeated Spider-Man after burying his adversary alive. Kraven was later resurrected by his family in a bid to restore honor to the Kravinoff family. Due to the sacrifice of Kaine. rather than Spider-Man, during the resurrection, Kraven now bestows the curse of the "unlife" where due to the totemistic nature of his rivalry with Spider-Man, can only die now at the hands of Spider-Man himself.
Spider-Man #47 (June 1994) Vladimir "Vlad" Kravinoff, the son of the original Kraven, is trained by his father's servant and his father to become a hunter akin to his father. Taking the name Grim Hunter
Grim Hunter
Grim Hunter is a fictional character, a supervillain in the Marvel Comics Universe, in which he is an enemy of Spider-Man. He is the son of Kraven the Hunter. His first appearance was in Spider-Man #47.-Fictional character biography:...

, Kravinoff sought to hunt both Spider-Man and the webslinger's foes. He met his first untimely end at the hands of Kaine, only later to be resurrected as a humanoid lion to die again at the mercy of his resurrected father.
Spectacular Spider-Man #243 (February 1997) Alyosha Kravinoff continued his father's legacy after his death.
Amazing Spider-Man #565 (September 2008) Teenager, Ana Tatiana Kravinoff, takes her father's legacy as a new version of Kraven the Hunter in the Kraven's First Hunt arc and after her father's resurrection dubs herself the Grim Huntress.
Lizard
Lizard (comics)
The Lizard is a fictional character, a supervillain in the Marvel Comics universe and enemy of Spider-Man. The Lizard first appeared in The Amazing Spider-Man #6 , and was created by Stan Lee and Steve Ditko...

 
Amazing Spider-Man #6 (November 1963) When he lost his arm during a war, Dr. Curt Connors felt like he lost a half of himself. Obsessed with regaining his lost limb, Connors creates a serum from reptilian DNA, in hopes of gaining reptile-like regeneration abilities. He regains his arm, but at a price: he becomes a humanoid lizard, with a savage personality. He eventually evolved and permanently became the Lizard as a result of the transformation. He devoured his son, Billy Connors, in his reptilian state.
Man-Wolf
John Jameson (comics)
John Jameson is a fictional character in publications from Marvel Comics.-Publication history:...

 
Amazing Spider-Man #124 (September 1973) John Jameson was a supporter of Spider-Man, no matter what his dad J. Jonah Jameson
J. Jonah Jameson
John Jonah Jameson Junior is a supporting character of Spider-Man in the .Jameson is usually the publisher or editor-in-chief of the Daily Bugle, a fictional New York newspaper and now serves as the mayor of New York City...

 said. John used to be an astronaut, which is how he discovered a gem on the moon. He kept it and made a pendant out of it on Earth. When he wore it during the full moon he turned into a werewolf creature that has sharp teeth, claws, superhuman strength, speed, agility, healing, stamina, and heightened senses. His intelligence is based upon the moon. Regardless of the moon phase, Man-Wolf is a bloodthirsty monster.
Mister Negative
Mister Negative
Mister Negative is a fictional comic book supervillain, appearing in books published by Marvel Comics, usually as an enemy of Spider-Man and the Punisher...

Amazing Spider-Man #546 (January 2008) Martin Li is a seemingly good willed philanthropist who runs a soup kitchen in Chinatown, the F.E.A.S.T. Project (Food, Emergency Aid, Shelter and Training), is also the notorious Chinatown crimeboss. He was responsible for curing Eddie Brock of the cancer that resulted from years of being attached to the symbiote, resulting in the birth of Anti-Venom.
Molten Man
Molten Man
Molten Man is a fictional character, a supervillain in the Marvel Universe. The character was created by Stan Lee and Steve Ditko and first appeared in The Amazing Spider-Man #28 .-Fictional character biography:...

Amazing Spider-Man #28 (September 1965) Mark Raxton was born in New York City. He was a scientist who could not wait to use his skills to become rich, and once worked at Osborn Industries, Inc., as the laboratory assistant to Dr. Spencer Smythe, creator of the Spider-Slayers. Raxton and Smythe developed an experimental new liquid metallic alloy for the Spider-Slayers from a radioactive meteor, but Raxton attempted to steal it and sell it for his own profit. In the ensuing fight with Smythe in the laboratory, Raxton spilled the liquid alloy all over himself, his skin absorbing it and turning golden. He was later cured by Harry Osborn.
Morbius
Morbius, the Living Vampire
Morbius, the Living Vampire, is a fictional character appearing in comic books published by Marvel Comics. Created by writer Roy Thomas and penciler Gil Kane, the character, a living human suffering from vampiric abilities resulting from scientific rather than supernatural means, first appeared as...

 
Amazing Spider-Man #101 (October 1971) Michael Morbius, a Nobel Prize-winning biochemist, attempts to cure himself of a rare blood disease with an experimental treatment involving vampire bats and electroshock therapy. He instead becomes afflicted with a far worse condition that mimics the powers and bloodthirst of vampirism. Morbius now has to digest blood in order to survive and a strong aversion to light. He gains the ability to fly, as well as superhuman strength and healing abilities.
Morlun
Morlun
Morlun is a fictional comic book supervillain in Marvel Comics' shared universe, the Marvel Universe, and a foe of Spider-Man. Morlun first appeared in The Amazing Spider-Man vol. 2, #30 , created by writer J. Michael Straczynski and penciler John Romita, Jr....

 
Amazing Spider-Man vol. 2 #30 (June 2001) Morlun is from a race called the Ancients, that feed on "totem
Totem
A totem is a stipulated ancestor of a group of people, such as a family, clan, group, lineage, or tribe.Totems support larger groups than the individual person. In kinship and descent, if the apical ancestor of a clan is nonhuman, it is called a totem...

" people like Spider-Man. While Spider-Man is learning the true intentions of totemistic hunters from his new friend Ezekiel
Ezekiel (comics)
Ezekiel Sims was a fictional character in the Marvel Comics universe; a former supporting character in The Amazing Spider-Man.-Fictional character biography:...

, Morlun readies for his next hunt: Spider-Man. His original hunt was for Ezekiel who also had Spider powers like Peter. Morlun is the only villain to have officially "killed" Spider-Man.
Mysterio
Mysterio
Mysterio is the name of three fictional characters, all of which are supervillains and enemies of Spider-Man in the . The original Mysterio was created by Stan Lee and Steve Ditko and first appears in Amazing Spider-Man #13, although it was later retconned that the aliens seen in Amazing...

Amazing Spider-Man #13 (June 1964) A disgraced stunt man and special effects artist named Quentin Beck dons an extravagant and theatrical costume as Mysterio and seeks to discredit and frame Spider-Man.
Amazing Spider-Man #141 (February 1975) After The Beck's apparent demises, Daniel Berkhart adopts the identity.
Spider-Man/Black Cat: The Evil that Men Do
Spider-Man/Black Cat: The Evil that Men Do
Spider-Man/Black Cat: The Evil That Men Do is a six-issue comic book limited series published by Marvel Comics starring the superhero Spider-Man and his ally, the cat burglar known as the Black Cat....

#1 (August 2002)
Teleporting mutant
Mutant (Marvel Comics)
In comic books published by Marvel Comics, a mutant is an organism who possesses a genetic trait called an X-gene that allows the mutant to naturally develop superhuman powers and abilities...

 Francis Klum
Mysterio (Francis Klum)
Mysterio is a fictional comic book supervillain appearing in books published by Marvel Comics, in particular as an adversary to Spider-Man...

also briefly becomes Mysterio, before Beck returns from the dead.
Puma
Puma (comics)
Puma is a fictional character in the Marvel Comics universe most closely associated with Spider-Man. While originally a villain, he gained a great respect for Spider-Man and became his occasional ally.-Publication history:...

 
Amazing Spider-Man #256 (September 1984) Thomas Fireheart is the latest in this line of men, used in mystic ceremonies and selective breeding to create a perfect warrior, with the ability to turn into a powerful humanoid mountain lion werecat. He was operating as a mercenary and had been hired by The Rose to kill Spider-Man, but was thwarted by Upton.
Rhino
Rhino (comics)
The Rhino is a fictional character that appears in comic books published by Marvel Comics. Created by writer Stan Lee and artist John Romita, Sr., the character first appeared in The Amazing Spider-Man #41 The Rhino (Aleksei Mikhailovich Sytsevich) is a fictional character that appears in comic...

 
Amazing Spider-Man #41 (October 1966) Aleksei Sytsevich is a poor immigrant from Russia who participates in an experiment that bonded a super-strong polymer to his skin and gave him enhanced strength, speed, and stamina.
Sandman
Sandman (Marvel Comics)
Sandman is a fictional character who appears in comic books published by Marvel Comics. A shapeshifter endowed through an accident with the ability to turn himself into sand, he eventually reformed, and became an ally of Spider-Man...

 
Amazing Spider-Man #4 (September 1963) While on the run from the law, the escaped convict Flint Marko finds himself on a remote beach during a nuclear weapon testing. His cells are spliced with sand molecules by the radiation, and his body becomes a mass of a sand-like substance and can replicate into multiple personalities of himself.
Scorpion  Amazing Spider-Man #20 (January 1965) Private investigator Mac Gargan was paid by J. Jonah Jameson
J. Jonah Jameson
John Jonah Jameson Junior is a supporting character of Spider-Man in the .Jameson is usually the publisher or editor-in-chief of the Daily Bugle, a fictional New York newspaper and now serves as the mayor of New York City...

 to undergo an experimental animal mutation therapy, imbuing him with super strength, speed, and endurance at the cost of his sanity. Donning a scorpion-based costume, he set out to defeat Spider-Man numerous times and take revenge on Jameson for taking away his humanity. Gargan was also the second Venom and imposed as the Dark Spider-Man during Dark Reign.
Shocker
Shocker (comics)
The Shocker or just Shocker is a fictional character that appears in comic books published by Marvel Comics. The character first appeared in The Amazing Spider-Man #46 and was created by writer Stan Lee and artist John Romita, Sr.-Fictional character biography:Herman Schultz was born in New York...

 
Amazing Spider-Man #46 (March 1967) A burglar gifted with a head for engineering, Herman Schultz develops a pair of gauntlets capable of throwing incredibly powerful vibrational blasts. He wears a gold and brown quilted costume to protect himself from the vibrations of his gauntlets.
Silvermane
Silvermane (comics)
Silvermane is a fictional Marvel Comics character. He is a supervillain and a prominent figure in the Maggia, a fictional organized crime syndicate that is analogous to the Mafia. He first appeared in The Amazing Spider-Man, Volume 1 #73...

 
Amazing Spider-Man #73 (Jun 1969) Silvio Manfredi, given the name "Silvermane" for his near-white hair, is a professional criminal originally from Sicily
Sicily
Sicily is a region of Italy, and is the largest island in the Mediterranean Sea. Along with the surrounding minor islands, it constitutes an autonomous region of Italy, the Regione Autonoma Siciliana Sicily has a rich and unique culture, especially with regard to the arts, music, literature,...

. He started his criminal career in an organized crime group called the Maggia
Maggia (comics)
The Maggia is a fictional international crime syndicate that has appeared in various comic book series published by Marvel Comics. The organization exists in Marvel's main shared universe, known as the Marvel Universe...

.
Spencer Smythe
Spencer Smythe
Spencer Smythe is a fictional character, a comic book villain in the Marvel Comics universe. He first appeared in The Amazing Spider-Man #25 . He is the father of Alistair Smythe.-Fictional character biography:...

 
Amazing Spider-Man #25 (June 1965) A robotic and arachnid expert convinced by Jameson's editorials that Spider-Man was a menace. Smythe created multiple Spider-Slayer
Spider-Slayer
The Spider-Slayers are a series of fictional robots in the Marvel Comics universe that were specifically designed to hunt down, capture, and/or kill Spider-Man.-Fictional character biography:...

s to catch and destroy Spider-Man, but fell gravely ill from being exposed to radiation. His son Alistair later takes up his legacy.
The Spider-Slayers
Spider-Slayer
The Spider-Slayers are a series of fictional robots in the Marvel Comics universe that were specifically designed to hunt down, capture, and/or kill Spider-Man.-Fictional character biography:...

 
Amazing Spider-Man #25 (June 1965) Spider-Slayers are robots designed to hunt down or kill Spider-Man first designed by Spencer Smythe
Spencer Smythe
Spencer Smythe is a fictional character, a comic book villain in the Marvel Comics universe. He first appeared in The Amazing Spider-Man #25 . He is the father of Alistair Smythe.-Fictional character biography:...

 then carried on by his son Alistair Smythe
Alistair Smythe
Alistair Smythe is a comic book supervillain, owned by Marvel Comics and existing in that company's Marvel Universe. He was one of the main foes of Spider-Man...

 who then turned into the Ultimate Slayer himself (see list of Spider Slayers).
Spot
Spot (comics)
The Spot is a fictional character, a comic book supervillain in the Marvel Comics universe and appearing as an enemy of Spider-Man. He was created by Al Milgrom and Herb Trimpe. Ohnn first appeared unnamed in Spectacular Spider-Man #97 and became The Spot in the following issue #98.-Fictional...

 
Spectacular Spider-Man #98 (January 1985) Jonathon Ohnn can enter himself through holes, or portals to the spot dimension and he can throw them as a weapon from his body.
Swarm
Swarm (comics)
Swarm is a fictional character and supervillain, an enemy of Spider-Man in the Marvel Comics universe. A former Nazi sympathizer, his most notable physical feature is that his entire body is composed of bees....

 
Champions #14 (July 1977) A former Nazi scientist Fritz Von Meyer was a bee keeper in South America. When a colony of mutated bees devoured him, his consciousness was absorbed into them, becoming a living swarm.
Tinkerer
Tinkerer
The Tinkerer is a fictional character, a supervillain appearing in comic books set in the Marvel Comics Universe...

 
Amazing Spider-Man #2 (May 1963) Originally thought to be an Alien from Amazing Spider-Man #2, the Tinkerer turned out to really be a brilliant man named Phineas Mason who is at the top his game in creating mechanical devices, mostly for supervillains.
Tombstone
Tombstone (comics)
Tombstone is a supervillain in the fictional Marvel universe. The character was created by Gerry Conway and Alex Saviuk and first appeared in Web of Spider-Man #36 .-Fictional character biography:...

 
Web of Spider-Man #36 (March 1988) Lonnie Thompson Lincoln is an African American
African American
African Americans are citizens or residents of the United States who have at least partial ancestry from any of the native populations of Sub-Saharan Africa and are the direct descendants of enslaved Africans within the boundaries of the present United States...

 albino who became a superhuman hitman and mob enforcer known as Tombstone. He has personal ties to Spider-Man supporting character, Robbie Robertson.
Venom
Venom (comics)
Eddie Brock is a fictional character created by David Michelinie and Todd McFarlane. A comic book supervillain, Brock's earliest appearance is a cameo in Web of Spider-Man #18 before making his first full appearance in The Amazing Spider-Man #299 as Venom...

Amazing Spider-Man #299 (April 1988) When Spider-Man rid himself of the alien symbiote
Symbiote (comics)
In the Marvel Comics universe, The Symbiote is a specific parasitic species of extraterrestrial organism...

 costume he acquired during the Secret Wars
Secret Wars
Marvel Super Heroes Secret Wars is a twelve-issue comic book crossover limited series published from May 1984 to April 1985 by Marvel Comics. The series was written by Jim Shooter with art by Mike Zeck and Bob Layton...

, it bonds with reporter Eddie Brock
Eddie Brock
Eddie Brock is a fictional character created by David Michelinie and Todd McFarlane. A comic book supervillain, Brock's earliest appearance is a cameo in Web of Spider-Man #18 before making his first full appearance in The Amazing Spider-Man #299 as Venom...

, who hates Spider-Man for causing him to lose his job and reputation. The symbiote, known as Venom gives Brock all of Spider-Man's powers, protection from his Spider-Sense, and the knowledge of Parker's secret identity. Brock would gain a new symbiote and face-off against Mac Gargan as Anti-Venom.
Marvel Knights Spider-Man #7 (December 2004) When Brock decides to turn his life around, the symbiote is sold at auction to Angelo Fortunato. Fortunato uses the Venom identity only briefly before the symbiote abandons him, causing his death.
Marvel Knights Spider-Man #9 (February 2005) After leaving Fortunato, the symbiote attaches itself to Mac Gargan, the super-villain formerly known as the Scorpion.
Vulture
Vulture (comics)
The Vulture is the name of six comic book supervillains in the Marvel Comics universe. The best known Vulture in the Marvel Universe is Adrian Toomes, an elderly enemy of Spider-Man created by Stan Lee and Steve Ditko in The Amazing Spider-Man #2 .-Golden Age Vulture:In Young Men #26, a scientist...

Amazing Spider-Man #2 (May 1963) The elderly Adrian Toomes turned to a life of crime after his business partner cheated him. With a self-invented anti-gravity pack, wings for faster flying, and a birdlike costume, he became the high-flying, lowdown. Ever since he was 14, Adrian Toomes has been taking sildenafil citrate tablets to stay alive. Vulture.
Amazing Spider-Man #48 (May 1967) "Blackie" Drago is a prison cellmate of Toomes' who tricks Toomes and steals the Vulture harness and costume. He uses the suit to make money through air piracy.
Amazing Spider-Man #127 (December 1973) Clifton Shallot is a university professor who gained an altered face, teeth, and fingernails and donned his own Vulture costume.
Amazing Spider-Man #592 (April 2009) Jimmy Natale was a mob cleaner who was transformed into a cannibalistic vulture creature who has a mutated jaw that spits acid and has developed real wings who mercilessly kills and eats criminals. ,

Foes of lesser renown

Villain First appearance Description
Answer
Answer (comics)
The Answer is the name of two fictional comic book characters, owned by Marvel Comics and appearing in that company's Marvel Universe. Aaron Nicholson first appeared in Peter Parker, the Spectacular Spider-Man #92. After his "death", S.H.I.E.L.D. agent, David Ferrari took the name of Answer in...

 
Lethal Foes Of Spider-Man #4 (July 1984) Originally, Aaron Nicholson was a very loyal hitman of the Kingpin known as the Answer, but later became an unconscious being of energy.
Armada Sensational Spider-Man (1988) Armada is a technology-using mercenary hired by Mysterio
Mysterio
Mysterio is the name of three fictional characters, all of which are supervillains and enemies of Spider-Man in the . The original Mysterio was created by Stan Lee and Steve Ditko and first appears in Amazing Spider-Man #13, although it was later retconned that the aliens seen in Amazing...

.
Basilisk
Basilisk (comics)
The Basilisk is the name of three fictional characters that appear in comic books published by Marvel Comics. The first is a supervillain who debuts in Marvel Team-Up #16 . The second is a mutant who first appears in New X-Men #135 . The third is a lizard-like villain who first appears in Morbius,...

 
Marvel Team-Up vol. 1 #16 (December 1973) Basil Elks is a petty thief who breaks into a museum to steal what he believes is an ordinary emerald - but is in fact a Kree
Kree
The Kree, also known as the Ruul, are a scientifically and technologically advanced militaristic alien race in the fictional Marvel Universe. They are native to the planet Hala in the Large Magellanic Cloud...

 artifact called the Alpha Stone. Elks gains multiple superpowers, when the stone shatters, by one of the museums security guards. Basilisk realizes that the Alpha Stone has a twin - the Omega Stone - which he becomes determined to find so as to increase his powers. Basilisk comes into conflict with Captain Marvel (who is seeking the Stones), Spider-Man, Mister Fantastic
Mister Fantastic
Mr. Fantastic is a fictional character, a Marvel Comics superhero and a member of the Fantastic Four. Created by writer Stan Lee and artist/co-plotter Jack Kirby, he first appeared in Fantastic Four #1 ....

, and finally the Mole Man
Mole Man
The Mole Man is a comic book supervillain that exists in Marvel Comics' main shared universe. He first appeared in Fantastic Four #1, and was created by Stan Lee and Jack Kirby.-Fictional character biography:...

 in his underground lair.
Big Wheel
Big Wheel (comics)
Big Wheel is a Marvel Comics supervillain created by Marv Wolfman, Ross Andru, and Mike Esposito. The character first appeared in The Amazing Spider-Man #182 .-Fictional character biography:...

The Amazing Spider-Man
The Amazing Spider-Man
The Amazing Spider-Man is an American comic book series published by Marvel Comics, featuring the adventures of the fictional superhero Spider-Man. Being the mainstream continuity of the franchise, it began publication in 1963 as a monthly periodical and was published continuously until it was...

#182 (July 1978)
Jackson Weele is a business man who has embezzled from his company who gets Tinkerer
Tinkerer
The Tinkerer is a fictional character, a supervillain appearing in comic books set in the Marvel Comics Universe...

 to create a large metal wheel that can climb up buildings, complete with guns and waldo-arms. With his new vehicle, Weele became the Big Wheel.
Big Man
Frederick Foswell
Frederick Foswell is a fictional character in the Marvel Universe.-Publication history:Frederick Foswell first appeared, as the Big Man, in The Amazing Spider-Man #10 , and was created by Stan Lee and Steve Ditko....


¤Frederick Foswell
Frederick Foswell
Frederick Foswell is a fictional character in the Marvel Universe.-Publication history:Frederick Foswell first appeared, as the Big Man, in The Amazing Spider-Man #10 , and was created by Stan Lee and Steve Ditko....


¤Janice Foswell 
Amazing Spider-Man #10 (March 1964)
Marvel Team-Up #39 (November 1975)
Frederick Foswell was a small and timid reporter working for the Daily Bugle
Daily Bugle
The Daily Bugle is a fictional New York City newspaper that is a regular fixture in the Marvel Universe, most prominently in Spider-Man comic titles and their derivative media...

 who aspired to be a crime boss. Taking on the identity of the Big Man, Foswell and his Enforcers
Enforcers (comics)
The Enforcers are a fictional team of villains in the Marvel Comics universe. Created by writer-editor Stan Lee and artist and co-plotter Steve Ditko, the team's first appearance was in The Amazing Spider-Man #10 .-Publication history:...

 attempted to take over the New York underworld. The daughter of the original Big Man, Janice Foswell sought to follow in the footsteps of her father and gain control of the New York underworld.
Black Fox
Black Fox (comics)
Black Fox is a code name used by two unrelated fictional characters in the Marvel Comics Universe: a villain and Dr. Robert William Paine, a superhero.-Black Fox :-Publication history:...

Amazing Spider-Man #255 (August 1984) Raul Chalmers is a jewel thief with a long international career. In his sixties, he yearns to pull off one last big heist so that he can retire for good to the French Riviera
Black Tarantula
Black Tarantula
Black Tarantula is a fictional character that appears in comic books published by Marvel Comics. The character first appears as an unseen character in The Amazing Spider-Man #419 , and makes his first full appearance in Amazing Spider-Man #432...

Amazing Spider-Man #419 (January 1997) Carlos LaMuerto is the most recent in a family line of superpowered vigilante martial artists, all posing as a single immortal figure.
Calypso
Calypso (comics)
Calypso is a fictional villain in the Marvel Comics universe, who first appeared in Amazing Spider-Man #209. She was created by Denny O'Neil and Alan Weiss.-Fictional character biography:...

 
Amazing Spider-Man #209 (October 1980) Calypso Ezili is a psychopathic voodoo woman who was associated with Sergei Kravinoff, aka Kraven the Hunter
Kraven the Hunter
Kraven the Hunter is a fictional character, a supervillain and enemy of Spider-Man appearing in comic books published by Marvel Comics. Kraven's name is Sergei Kravinoff. He also appears as Xraven, with white-grey skin and red eyes, possessing the powers of X-Men. He is the half-brother of Dmitri...

.
Carrion
Carrion (comics)
Carrion is a fictional character, a supervillain appearing in the Marvel Comics universe, in which he is an enemy of Spider-Man. He first appeared in The Spectacular Spider-Man #25....


¤Miles Warren clone
¤Malcolm McBride
¤Dr. William Allen 
Spectacular Spider-Man #25 (December 1978)
Spectacular Spider-Man #149 (April 1989)
Spider-Man: Dead Man's Hand (1997)
The first Carrion was originally an extremely decayed and superpowered clone of Dr. Miles Warren
Jackal (Marvel Comics)
The Jackal is a fictional character that appears in comic books published by Marvel Comics. The character first appears in The Amazing Spider-Man #129 , and was created by writer Gerry Conway and artist Ross Andru. In The Amazing Spider-Man #148 The Jackal is a fictional character that appears in...

.

The second Carrion was a college student named Malcolm McBride who had discovered a genetic virus which mutated him into Carrion, who had all the powers and memories of the original Carrion.

While examining the corpse of Miles Warren, Dr. William Allen was infected with an extremely powerful version of the Carrion virus. Using its power to manipulate the minds of others, Carrion III went on a killing spree in New York City. It was only by using the Jackal's old scientific notes that Spider-Man managed to cure Dr. Allen of the Carrion plague.
Chance
Chance (comics)
Chance is the name of two unrelated fictional characters in the Marvel Universe. The first is a mercenary and enemy of Spider-Man, the second a mutant who originally appeared in Fallen Angels vol. 1 #1.-Chance :...

Web of Spider-Man #15 (June 1986) Nicholas Powell was looking for more thrill in his life. He decides to become a mercenary criminal-for-hire, incorporating his love of gambling into his work. Anyone who hires him would, instead of directly paying, bet his fee against him actually completing the mission.
Coldheart
Coldheart
Coldheart is a fictional comic book supervillainess in the Marvel Comics universe. The ice-powered, sword-using female was created by Howard Mackie and Tom Lyle. Unseen for years, she presumably died during the start of Civil War....

Spider-Man #49 (1994) Kateri Deseronto was once a government agent with the codename Coldheart. She has a bulletproof
Bulletproof
Bulletproofing is the process of making something capable of stopping a bullet or similar high velocity projectiles e.g. shrapnel. The term bullet resistance is often preferred because few, if any, practical materials provide complete protection against all types of bullets, or multiple hits in the...

 costume and with two swords, one to paralyze and the other to freeze objects. She is proficient in martial arts and sword fighting. After her son's death during a battle between the Hobgoblin and Spider-Man, she was deemed mentally unfit for field duty. Her clearance was revoked and she was forcibly retired. She later confronts both Spider-Man and Hobgoblin, in revenge, after stealing her costume back. Coldheart is arrested and imprisoned in the Raft
The Raft (comics)
The Raft is a fictional island prison facility in New York City for psychopathic superhuman criminals appearing in comic books published by Marvel Comics...

. Coldheart is apparently one of the many villains that escaped from the Raft. Hiding in Stamford with some other escaped convicts, she was eventually tracked down by the New Warriors
New Warriors
The New Warriors is a Marvel Comics superhero team, traditionally consisting of young adult heroes. They first appeared in The Mighty Thor #411 .-General publication history:...

. During the battle, Nitro
Nitro (comics)
Nitro is a fictional character, a supervillain in the Marvel Comics universe. He first appeared in Captain Marvel #34 and was created by Jim Starlin....

 used his powers and caused an explosion in the neighborhood, causing both the death of hundreds of people, the New Warriors, and presumably Coldheart as well.
Cyclone The Amazing Spider-Man #143 (April 1975) André Gerard, a French engineer working for NATO, Gerard had a falling out with his former employees, related to political decisions over implementing his research, based on the development of a weapon that generates high velocity tornado-like winds. Cyclone took his invention and used it for his own criminal ends, developing his costume and other weapons
Delilah
Delilah (comics)
Delilah is a fictional Marvel Comics character, a Spider-Man villain from the 1990s and an enforcer of the Rose. She first appeared in The Amazing Spider-Man #414 , created by Tom DeFalco and Mark Bagley.-Fictional character biography:...

Amazing Spider-Man #414 (August, 1996) The Rose's confidante as well as his chief enforcer, Delilah helped battle to maintain control of part of the New York crime scene against the threat of the Black Tarantula. She had a role in the rebirth of two of Spider-Man's old foes during the Rose's efforts to gain extra muscle: she was the one who threw the switch of the electric chair which gave Electro his powers back, and helped set up the theft of Doctor Octopus' corpse for reanimation from the Hand
Hand (comics)
The Hand is a fictional supervillainous organization in the Marvel Comics universe.The Hand is an order of evil mystical ninja who are heavily involved in organized crime and mercenary activities such as assassination plots. The Hand covets power above all other objectives. They are primarily based...

.
Demogoblin
Demogoblin
Demogoblin is a fictional character appearing in the Marvel Comics universe. He first appeared as Demogoblin in Web of Spider-Man #86 , and had previously appeared as an unnamed demon in Spectacular Spider-Man #147....

 
Web of Spider-Man #86 (March 1992) The fourth Hobgoblin
Hobgoblin (comics)
The Hobgoblin is the alias of several fictional characters that appears in comic books published by Marvel Comics. The first and best-known Hobgoblin is Roderick Kingsley. He first appeared in The Amazing Spider-Man #238, and was created by Roger Stern and John Romita, Sr...

, Jason Macendale, wanting power, attempted to sell his soul to the demon N'astirh
N'astirh
N'astirh is a fictional character created by Marvel Comics as a demonic inhabitant of Limbo. He first appeared in X-Factor #32 and was created by Louise Simonson and Jon Bogdanove.-Fictional character biography:...

 during the Inferno Crisis
Inferno (Marvel Comics)
Inferno was a Marvel Comics company-wide crossover in 1989 that mainly involved the mutant titles, namely The Uncanny X-Men, X-Factor, X-Terminators, Excalibur, and The New Mutants...

. An amused N'astirh declined Macendale's soul and instead grafted a demon to Macendale, "without a catch". Unfortunately for Macendale, the fusion of himself and the demon gave him a hideous appearance and drove him insane. After months of fighting for control of Macendale's body, the demon physically tore himself from Macendale and, christening itself the Demogoblin, set off to purge the world of "sinners".
Doppelganger
Doppelganger (comics)
The Doppelganger, also called the Spider-Doppelganger, is a fictional character and supervillain in the Marvel Comics universe. It first appeared in The Infinity War #1.-Fictional character biography:...

 
Infinity War #1 (June 1992) A magically created clone of Spider-Man, the Doppelganger was created by the Magus
Magus (comics)
The Magus is a fictional character, a Marvel Comics supervillain. He is an evil version of the hero Adam Warlock.-Publication history:The Magus was created by Jim Starlin, and appears as an image in Strange Tales vol...

 to kill Spider-Man.
Empathoid The Spectacular Spider-Man #6 (May 1977) A fire-body who enters other bodies and hires them. He first entered the body of Morbius
Morbius, the Living Vampire
Morbius, the Living Vampire, is a fictional character appearing in comic books published by Marvel Comics. Created by writer Roy Thomas and penciler Gil Kane, the character, a living human suffering from vampiric abilities resulting from scientific rather than supernatural means, first appeared as...

 and hired him to attack Spider-Man. He later entered Spider-Man's body and hired him to attack Morbius.
Finisher Amazing Spider-Man Annual #5 An assassin employed by the fascist Red Skull
Red Skull
The Red Skull is a name shared by several fictional characters, all supervillains from the Marvel Comics universe. All incarnations of the character are enemies of Captain America, other superheroes, and the United States in general....

 who killed Spider-Man's parents
Richard and Mary Parker
Richard and Mary Parker are fictional characters of Marvel Comics. They were the parents of Peter Parker, the boy who one day would become Spider-Man. They will appear in the 2012 reboot of the Spider-Man film franchise...

. Spider-Man kills Finisher in self defense by turning his own missile against him.
Richard Fisk
Richard Fisk
Richard Fisk is a fictional character, a criminal in the , featured in the comic books published by Marvel Comics. He is the son of the Kingpin and his wife Vanessa Fisk...

 
Amazing Spider-Man #83 Richard Fisk, the son of crime lord Wilson Fisk
Kingpin (comics)
The Kingpin is a fictional character, a supervillain in the . Kingpin is one of the most feared and powerful crime lords in the Marvel Universe. The character is a major adversary of Daredevil, the Punisher, and Spider-Man...

, is an antihero who has adopted several identities over the years, most notably The Rose. Although his goals are noble ones, the methods he uses cause more harm than good.
Foreigner Web of Spider-Man #15 (June 1986) The Foreigner is a mercenary and assassin. Although he has no superhuman abilities, he has trained his body to be in absolute peak physical condition.
Vincente "Don" Fortunato
Don Fortunato
Vincente Fortunato is an elderly crime boss and enemy of the Marvel Comics superhero Spider-Man. He first appeared in Spider-Man #70. He is affiliated with the Maggia and HYDRA, and a competitor to the Kingpin.-Fictional character biography:...

Spider-Man #70 (May 1996
1996 in comics
-Year overall:* Malcolm Jones III commits suicide at circa age 37.* Boody Rogers, creator of Sparky Watts, dies at c. age 92-January:* January 19: Bernard Baily, co-creator of The Spectre and Hourman, dies at age 79.* January 28:...

)
A mob boss affiliated with the Maggia
Maggia (comics)
The Maggia is a fictional international crime syndicate that has appeared in various comic book series published by Marvel Comics. The organization exists in Marvel's main shared universe, known as the Marvel Universe...

 and HYDRA
HYDRA
HYDRA is a fictional terrorist organization in the Marvel Universe.Despite the name's capitalization per Marvel's official spelling, the name is not an acronym but rather a reference to the mythical Lernaean Hydra...

, who attempts to fill the vacuum of power in the absence of the Kingpin.
Freak
Freak (Marvel Comics)
Freak is the name of three fictional characters in the Marvel Universe. Most villains known as Freak are associated with Iron Man, while the most recent version appears in The Amazing Spider-Man.-Happy Hogan:...

 
Amazing Spider-Man #552 (March 2008) A drug addict named "Freak" is chased down by Spider-Man after he attempted to steal from the poor at the soup kitchen Spider-Man's Aunt May
Aunt May
May Reilly Parker-Jameson, commonly known as Aunt May, is a supporting character in Marvel Comics' Spider-Man series. Created by writer Stan Lee and artist Steve Ditko, she first appeared as May Parker in Amazing Fantasy #15...

 works at. He stumbles into a laboratory owned by Curt Connors and injects himself with animal gene fluids, thinking they were crystal meth. Freak then began to form a chrysalis around his body, emerging as a skinless monster. He blames Spider-Man and wants revenge.
Fusion (Hubert and Pinky Fusser) Amazing Spider-Man vol. 1 #208 Hubert and Pinky Fusser are twins both born with dwarfism. One becomes a nuclear scientist, and one becomes janitor at the same privately-owned research corporation where his brother works. When an accident strikes Hubert, his brother rushes to assist. The resulting radiation causes them to become one, a Fusion - a twin-headed radioactive being which contains both of their personalities. The brothers have superhuman strength, and they can glow and emit radiation.
Fusion (Mr. Markley) Peter Parker: Spider-Man vol. 2 #30 Mr. Markley is a millionaire who can get anything he wants. Markley can persuade people to do what he wants, to see what he wants, and to hear what he wants, controlling people's perceptions. After his son, Francis, dies as a result of trying to imitate Spider-Man, he takes revenge on Spider-Man as Fusion. He attacks and brutally beats Spider-Man by morphing his body parts into those of various heroes. Capturing and brutally torturing Spider-Man in an abandoned warehouse, Fusion is defeated when Spider-Man, realizing the nature of Fusion's powers, manages to pummel him into submission. When he next appears, Fusion, having teamed-up with Doctor Octopus, through a bizarre plot of dismembering and mind-controlling people, manages to get a device which allows him to track Spider-Man. Soon after gaining the device, Fusion is beaten horribly by the traitorous Doctor Octopus
Doctor Octopus
Doctor Octopus is a fictional character, a supervillain that appears in comic books published by Marvel Comics since 1963. A highly intelligent mad scientist, Doctor Octopus is one of Spider-Man's greatest foes...

 and is left for dead, but yet he survives.
Gog
Gog (Marvel Comics)
Gog is a fictional character, a comic book supervillain in the . Created by writer Roy Thomas and Gil Kane, the character first appears in The Amazing Spider-Man #103....

 
Amazing Spider-Man #103 (December 1971) Gog is an alien that was saved from death by Kraven the Hunter when Gog was a baby. Kraven raised him and Gog became a huge monster with super strength and bracelets that allow interdimensional teleportation. He would later become a Sinister Six member.
Grey Goblin  Amazing Spider-Man #509 Before her death, Gwen Stacy and Norman Osborn had an affair and Gwen became pregnant with twins: Gabriel and Sarah. Gabriel, like his sister, were born with the goblin formula in their system. Due to this, they both age much faster than a normal human, appearing as adults despite being around 9 years old. After a second dose of Goblin formula, Gabriel took the mantle of Grey Goblin and became very much insane.
Grizzly
Grizzly (comics)
Grizzly is the name of four unrelated fictional characters from the Marvel Comics universe. One is a wild west villain, one is an A.I.M. Agent, one is a foe of Spider-Man, and the fourth is a mutant who was a member of Six Pack.-Grizzly :...

 
Amazing Spider-Man #139 (December 1974) Maxwell Markham is a professional wrestler who competed using the nom de guerre of the Grizzly. His violent actions brought him to the attention of J. Jonah Jameson whose article got Maxwell expelled from wrestling. Ten years later, he met with the Jackal who gave him a grizzly bear suit and an exoskeleton harness that amplified his strength and durability. He used this harness to attack the Daily Bugle in an attempt on revenge against Jameson for ruining his wrestling career.
Jonas Harrow
Jonas Harrow
Jonas Harrow is a fictional character, a supervillain in the Marvel Comics Universe, in which he is an enemy of Spider-Man.-Publication history:...

Amazing Spider-Man #114 (October 1972) Jonas Harrow was disgraced as a surgeon and expelled from the medical profession for unorthodox experiments. Jonas Harrow is a genius surgeon, geneticist, cyberneticist, and machinesmith who has help to create Hammerhead
Hammerhead (comics)
Hammerhead is a fictional character, a supervillain that has appeared in various comic book series published by Marvel Comics. He is primarily an enemy of Spider-Man and a member of organized crime who exists in Marvel's main shared universe, known as the Marvel Universe...

 and enhanced many other supervillains.
Herd, Gregory Amazing Spider-Man vol. 2 #2 (as Shadrac) Gregory Herd wore a cybernetically enhanced costume that allowed him to control or "override" any other electronic device and worked as a mercenary for hire. He later became Shadrac.
Hitman
Hitman (Marvel Comics)
Hitman is a fictional character that appears in comic books published by Marvel Comics.-Publication history:Burt Kanyon, also known as the Hitman, first appeared in The Spectacular Spider-Man #4 , and was created by Archie Goodwin and Sal Buscema...

Spectacular Spider-Man #4 (March 1977) Burt Kenyon was a costumed mercenary assassin. He was hired by the Maggia as their version of the Punisher. The Vulture had rejected the Maggia's offer before they hired the Hitman, so the Hitman was sent to humiliate the Vulture by killing Spider-Man before the Vulture could.
Human Fly
Human Fly (comics)
The Human Fly is the name of two comic book characters in the Marvel Comics universe, one a super-villain that was an occasional antagonist of Spider-Man, and the other a superhero. Additionally, Human Fly was the title of a short-lived series in the late 1950s reprinting some of Fox's Blue Beetle...

Amazing Spider-Man Annual #10 (1976) Richard Deacon was born in Newark, New Jersey. He was a small-time criminal who was shot by the police and left for dead after his unsuccessful kidnapping attempt, which was foiled by Spider-Man. Stumbling into the laboratory of Dr. Harlan Stillwell (whose brother Farley Stillwell created the Scorpion for J. Jonah Jameson), Deacon coerced the scientist into saving his life. Overhearing an offer Jameson made with Stillwell to fund the creation of a new superhero, Deacon insisted he be the subject of the experiment. Stillwell imprinted the genetic coding of a common fly onto Deacon, empowering him and healing him of his bullet wounds. Deacon killed Harlan Stillwell and used his newfound powers to further his criminal ambitions. He first used Jameson as bait to get revenge on Spider-Man, but due to his inexperience he was no match for the web-slinger and he was defeated.
Hypno-Hustler
Hypno-Hustler
The Hypno-Hustler is a fictional character, a comic book supervillain in the Marvel Comics universe. Created by Bill Mantlo and Frank Springer, the character first appeared in The Spectacular Spider-Man #24.-Fictional character biography:...

Spectacular Spider-Man #24 Created by Bill Mantlo
Bill Mantlo
Bill Mantlo is an American comic-book writer, primarily at Marvel Comics, best known for his work on two licensed toy properties whose adventures occurred in the Marvel Universe: the Eagle Award-winning Micronauts and the long-running Rom. An attorney, he also worked as a public defender...

 and Frank Springer
Frank Springer
Frank Springer was an American comic book and comic strip artist best known for Marvel Comics' Dazzler and Nick Fury, Agent of S.H.I.E.L.D....

, Hypno-Hustler can perform hypnosis with the aid of his guitar, and when teamed with his backup band, The Mercy Killers, can perform mass hypnosis. His boots can emit knockout gas on demand, and have retractable knives in the soles. The Hypno-Hustler also appeared in Spider-Man: Reign
Spider-Man: Reign
Spider-Man: Reign is a four-issue comic book limited series featuring Spider-Man, written and illustrated by Kaare Andrews and published by Marvel Comics...

, a limited series
Limited series
A limited series is a comic book series with a set number of installments. A limited series differs from an ongoing series in that the number of issues is determined before production and it differs from a one shot in that it is composed of multiple issues....

 set in the future, at the end of Spider-Man's career.
Iguana
Iguana (comics)
Iguana is a fictional character in the Marvel Universe.-Publication history:The Iguana appears in Spectacular Spider-Man #32-34 , and was created by Bill Mantlo and Jim Mooney.-Fictional character biography:...

 
Spectacular Spider-Man #32 (July 1979) An iguana that can turn into a humanoid form with a hypnotic stare and all of the abilities of the Lizard
Lizard (comics)
The Lizard is a fictional character, a supervillain in the Marvel Comics universe and enemy of Spider-Man. The Lizard first appeared in The Amazing Spider-Man #6 , and was created by Stan Lee and Steve Ditko...

 (though not as skilled).
Jack O'Lantern
Jason Macendale
Jason Philip Macendale, Jr. is a fictional character that appears in comic books published by Marvel Comics. The character first appears in Machine Man #19 , and was created by writer Tom DeFalco and artist Steve Ditko....

 
Machine Man #19 (February 1981) Jason Philip Macendale, known as the original Jack O'Lantern, has no super powers but wares a flaming pumpkin mask and hurls explosive grenades while flying on a disc glider or hopping about on a "pogo platform". He later became the second Hobgoblin.
Kangaroo
Kangaroo (comics)
The Kangaroo is the alias of two fictional Spider-Man villains in the Marvel Universe. The first was introduced in The Amazing Spider-Man #81 in 1970; the second was first seen in Cage #13 in 1993 and made his debut in The Spectacular Spider-Man #242 in 1997...


¤Brian Hibbs
¤Frank Oliver 
Amazing Spider-Man #81 (February 1970)
Spectacular Spider-Man #242
Frank Oliver was the first Kangaroo but only had two overall appearances in Amazing Spider-Man #81 & 126. #126 showed the Kangaroo off with his "powered-up" powers courtesy of Dr. Jonas Harrow, the man also responsible for Hammerhead's hard head. Unfortunately, the powers, not to mention radiation poisoning
Radiation poisoning
Acute radiation syndrome also known as radiation poisoning, radiation sickness or radiation toxicity, is a constellation of health effects which occur within several months of exposure to high amounts of ionizing radiation...

, got the best of Frank and it killed him.

A second Kangaroo, Brian Hibbs, jumped onto the scenes in Spectacular Spider-Man #242 with a very brief appearance. Brian Hibbs showed up again as a member of the Legion of Losers along with teammates Grizzly, Gibbon, and the Spot.
Lightmaster
Lightmaster
Lightmaster is a fictional character, a supervillain in the Marvel Comics universe.-Fictional character biography:Edward Lansky was born in New York City...

Peter Parker, the Spectacular Spider-Man #3 (February 1977) Edward Lansky was a physics professor and vice-chancellor of Empire State University who turned to crime and became a criminal mastermind as a way to prevent budget cuts for higher education that would have negatively affected the university. Lansky created a unique special body suit with a padded inner lining, a power armor suit which utilized "gravity-pump circuitry" to allow him to manipulate photons for a variety of effects.
Living Brain
Living Brain
The Living Brain is a fictional comic book supervillain and robot in the . Created by writer Stan Lee and Steve Ditko, the character first appears in The Amazing Spider-Man #8 and has made few subsequent appearances since....

The Amazing Spider-Man #8 The Living Brain was created by the International Computing Machines Corporation and billed as the most intelligent computer and robot in existence, capable of solving virtually any question asked of it.
Lobo Brothers
Lobo Brothers
The Lobo Brothers are two supervillains from Marvel Comics.-Publication history:The Lobo Brothers first appeared in Spectacular Spider-Man #143 , and were created by Gerry Conway and Sal Buscema....

Spectacular Spider-Man #143 (October 1988) Carlos and Eduardo Lobo grew up in poverty on the streets of Puebla de Zaragoza, Mexico, surviving by stealing and scavenging for food. As a teenager, Eduardo had fallen in love with a girl name Esmelda Valdez, the daughter of a wealthy ranch owner. The two had a romantic relationship until it was discovered by Esmelda's brother Ramon Valdez. One full moon night, Ramone and his men ambushed the two lovers and tried to drive Eduardo away by using whips on him. Pain and rage from this whipping triggered a mutant change in Eduardo's body. Carlos also discovered he was a mutant werewolf and the brothers turned to crime, using their powers to unite all the mobs of South Texas into Los Hermanos De La Luna. The Lobos were so successful that they not only gained a mansion in a Dallas suburb but drew the attention of the Arranger, the Kingpin's lieutenant. The Arranger used the Persuader to brainwash the Punisher into attempting an assassination of the Lobo Brothers. The plan failed thanks to Spider-Man's interference and the iron will of the Punisher, who ended up killing the Persuader instead. The Lobo Brothers knew who was responsible for the attempt and they vowed revenge.
Looter
Looter (comics)
The Looter is a fictional character, a supervillain who appears in the Spider-Man comic books published by Marvel Comics.-Publication history:...

Amazing Spider-Man #36 (May 1966) Norton G. Fester was always a poor scientist, and was considered a crackpot by his colleagues. One day, however, he found an unusual meteor that crashed into the Earth. Excited by his discovery, Fester searched for funding into a project, but investors went for more commercial ventures. Fester decided to continue without funding, and while chiseling the meteor, he struck a pocket of gas. Immersed in the strange compound, he discovered that he now had super strength and agility thanks to the meteor's powers. Fester decided to devote his time and new powers to crime from then on. Calling himself the Looter, he struck banks and offices everywhere, finally trying to steal a similar meteorite in case his powers wore off, however Spider-Man then captured him.
Massacre Amazing Spider-Man #655 (March 2011) Marcus was a man who was with his wife when a bomb went off. Shrapnel damaged his brain and caused mental unstability. He seeked vengeance. He became the Massacre! Portrayed in the "No One Dies" section of the "Big Time" story line in 2010-2011, by Dan Slott.
Jake Martino Amazing Spider-Man #537 (February 2007) Jake Martino is a small-time hitman hired by the Kingpin to kill Aunt May, though he only succeeds in shooting and wounding her. Spider-Man resolves to straight-out murder Martino after discovering he was the shooter, but he is shot by another Kingpin assailant before Martino is able to give out the identity of his boss.
Menace  Amazing Spider-Man #549 (February 2008) Lily Hollister transforms into Menace rather than putting on a costume. He bears a strong resemblance to the Green Goblin
Green Goblin
The Green Goblin is a fictional character, a supervillain who appears in the comic books published by Marvel Comics. The character was created by writer Stan Lee and artist Steve Ditko, and first appeared in The Amazing Spider-Man #14 ....

/Hobgoblin
Hobgoblin (comics)
The Hobgoblin is the alias of several fictional characters that appears in comic books published by Marvel Comics. The first and best-known Hobgoblin is Roderick Kingsley. He first appeared in The Amazing Spider-Man #238, and was created by Roger Stern and John Romita, Sr...

 villains and uses the same style of Goblin Glider. Peter suspected that Harry Osborn is Menace but had Lily Hollister, his latest girlfriend, verify he was not gone during the time Peter fought Menace. The only thing known is that he's been hunted down by Jackpot
Jackpot (comics)
Jackpot is the hero name shared by two fictional comic book characters, Sara Ehret and Alana Jobson, owned by Marvel Comics and primarily appearing in Spider-Man's stories...

 since his escape from robbing a bank truck. During her search, she meets Spider-Man and reluctantly takes his help. Menace then attacks a council meeting and kidnaps a council woman, and Spider-Man and Jackpot attack him. Unfortunately, Menace's glider slams into the rescued council woman, and Menace escapes the crime scene but not before accusing Spider-Man of being responsible for the woman's death. Recent developments have revealed that Menace uses Osborn's Goblin technology (Osborn recognized it) and he appears to be supporting the Hollister campaign... by threatening Bill Hollister.
Mindworm
Mindworm
The Mindworm is a Marvel Comics character and a former enemy of Spider-Man. The character first appeared in The Amazing Spider-Man #138.-Fictional character biography:...

 
Amazing Spider-Man #138 William Turner was a superhuman mutant with limited telepathic powers. He had an over sized cranium and was naturally extremely intelligent. Eventually, Mindworm attempted to reform but his problems were too difficult for him to control and he allowed himself to be killed by common street thugs to end his great suffering.
Mirage
Mirage (Marvel Comics)
Mirage is a fictional Marvel Comics villain. He first appeared in The Amazing Spider-Man #156.-Fictional character biography:Desmond Charne was a former holography technician who wanted to be a supervillain. To that end, he used holograph technology which could make him invisible or create 3-D...

 
Amazing Spider-Man #156 (May 1976) Desmond Charne is a former holography technician who wanted to be a supervillain. To that end, he uses holograph technology which could make him invisible or create 3-D illusions.
Miss Arrow
Miss Arrow
Miss Arrow is a fictional character in the Marvel Universe. She was created by Peter David, Mike Wieringo, and Todd Nauck.-The Other:During the events of The Other, Spider-Man died fighting his enemy Morlun...

Friendly Neighborhood Spider-Man #4 (January 2006) A being composed of pirate spiders first seen in The Other, disguising herself as a human woman, she met Flash Thompson
Flash Thompson
Eugene "Flash" Thompson is a supporting character in Marvel Comics’s Spider-Man series. Created by writer Stan Lee and artist Steve Ditko, he first appeared in Amazing Fantasy #15 ....

 and developed a fixation on him.
Overdrive Spider-Man Swing Shift (Free Comic Book Day
Free Comic Book Day
Free Comic Book Day is an annual promotional effort by the North American comic book industry to help bring new readers into independent comic book stores. Retailer Joe Field of in Concord, CA brainstormed the event in his "Big Picture" column in the August 2001 issue of Comics & Games Retailer...

, 2007)
A Spider-Man fanboy who uses a souped-up car including an electric hood and flaming exhaust.
Polestar
Polestar (comics)
Polestar is the name used by a pair of mercenaries and antagonists of Spider-Man, closely associated with the Great Game. The first is currently deceased.-Polestar I:...

Amazing Spider-Man vol. 1 #409 (March, 1996) A pair of mercenaries who used a costume and gauntlets that gave them significant control over various magnetic properties.
Queen Spectacular Spider-Man vol. 3 #15 (December 2004) Adriana Soria is the first female marine in combat during World War II. Adriana and a number of other soldiers are exposed to radiation at Bikini Atol in an attempt to create more super-soldiers. All but Adriana die during this experiment. The mental strain of the experiment unhinges Adriana's mind and she is placed in a military asylum and forgotten. Adriana is a latent mutant who's radiated genetic structure made her into an insect human hybrid, who appears human. Queen surfaces in New York with the ability to control anyone with "insect genes" including those with retrograde DNA pieces. She is able to mutate the DNA in Spider-Man resulting in his becoming a monstrous spider creature before reverting mostly to his original form (Spider-Man gains the ability to generate organic webs). It was Queen's hope that this monstrous spider would give birth to a child for her. Queen is seemingly killed by an explosion when Spider-Man defeated her though her body was never found. She has recently returned alive.
Raptor
Raptor (comics)
Raptor is the name of two fictional characters in the Marvel Comics' universe.The first Raptor appeared in the Spider-Girl series in the alternative future MC2 universe. She is the daughter of the criminal Blackie Drago .The second Raptor appears in the The Amazing Spider-Man...

 
Amazing Spider-Man Annual #36 (July 2009) Damon Ryder had his family killed in a fire apparently started by Ben Reilly
Ben Reilly
Benjamin "Ben" Reilly is a fictional character in the . He is a clone of Peter Parker , and is prominent in the "Clone Saga" story arc...

 while he was in Portland, Oregon. He has since then been obsessed with revenge on Reilly, and finds Peter Parker in Boston at the reunion with the Reilly family. Raptor then proceeds to attack and try to kill Peter, thinking he's really Ben Reilly. The full details on what happened in Portland still remain unclear. Raptor has arm claws (similar to Spider-Man's during "The Other" storyline), massive fangs, and super strength.
Ringer
Ringer (comics)
Ringer is the name of two comic book supervillains in the Marvel Comics universe.-Publication history:The fictional character of the Ringer was initially introduced in the Marvel comic book Defenders issue #51 , and was created by writer David Anthony Kraft and artist Keith Giffen...

 
The Defenders #51 (September 1977) Career criminal Anthony Davis hired the Tinkerer to build him a battlesuit. Upon testing the suit by himself, the Beetle broke into his workshop and the two battled, resulting in Davis becoming the Beetle's prisoner. The Beetle wanted Davis to wear the suit so they could fight Spider-Man together, and convinced Davis to do so because of the deadly explosive weapons built inside the suit.
Scarecrow
Scarecrow (Marvel Comics)
The Scarecrow is a fictional character, a supervillain in the Marvel Comics Universe, in which he is an enemy of Captain America, Spider-Man, Ghost Rider, and Iron Man. His first appearance was in Tales of Suspense #51....

 
Tales of Suspense #51 (March 1964) Ebenezer Laughton was an expert escapologist and contortionist at a circus until he turned to a life of crime. He armed himself with a pitchfork and trained killer crows to become the Scarecrow. After going in and out of jail multiple times from losing to heroes like Spider-Man he became criminally insane, and a mass murderer. He would later on get super powers, including the power to induce fear into his victims.
Scream
Scream (comics)
Scream is a fictional supervillainess from the Spider-Man comic book series. She is one of six symbiote spawns of Venom.-Fictional character biography:...

 
Venom: Lethal Protector #4 (1993) AKA Donna Diego, Scream was one of the five Life Foundation Symbiotes that were forcefully spawned from the Venom symbiote. She was their unofficial leader.
Scorcher
Scorcher (comics)
Scorcher is a Marvel Comics supervillain.-Fiction character biography:Steven Hudak was a research chemist who was wrongfully accused of embezzlement by his employer...

Untold Tales of Spider-Man vol. 1 #1 (September 1995) Steven Hudak was a research chemist who was wrongfully accused of embezzlement by his employer. Swearing revenge, he created an armored suit containing flame-throwing equipment and taking the name "The Scorcher" he attacked his former place of employment.
Scorpia
Scorpia (comics)
Scorpia is a fictional super villain in the Marvel Comics universe. A psychotic female version of the Scorpion, Scorpia is a long-time enemy of Spider-Man...

Spider-Man: The Power of Terror #2 (February 1995) Elaine Colls is a mental patient at Bellevue Hospital in Hell's Kitchen. She is chosen by Silvermane to become the new Scorpion after the retirement of the original; however, she opted to call herself Scorpia.
Screwball Amazing Spider-Man #559 Screwball's spectacular stunts and heists are all done for publicity and fame. She uses live streaming to get her videos online.
Sentry Peter Parker: Spider-Man vol. 2 #4 (April 1999) A former S.H.I.E.L.D.
S.H.I.E.L.D.
S.H.I.E.L.D. is a fictional espionage and a secret military law-enforcement agency in the Marvel Comics Universe. Created by Stan Lee and Jack Kirby in Strange Tales #135 , it often deals with superhuman threats....

 agent operating as Sentry, Steward Ward is a double agent
Double agent
A double agent, commonly abbreviated referral of double secret agent, is a counterintelligence term used to designate an employee of a secret service or organization, whose primary aim is to spy on the target organization, but who in fact is a member of that same target organization oneself. They...

 for Z'Nox aliens, who use Ward to aid in an invasion of Earth. Years later, as Z'Nox aliens found themselves on Earth during a brief period when it was designated an intergalactic prison
Supermax
Supermax is the name used to describe "control-unit" prisons, or units within prisons, which represent the most secure levels of custody in the prison systems of certain countries...

, Ward is infected by Z'Nox life-form, mutating him into a half-human/half-alien being. Ranger subsequently sacrificed himself to destroy Ward.
Shathra
Shathra
Shathra is a Spider-Man villain and a character in the Marvel Comics universe.-Fictional character biography:Shathra is a totem of the spider wasp, much as Spider-Man is rumored to be a totem of the spider...

 
Amazing Spider-Man vol. 2 #46 Shathra is, much as Spider-Man is rumored to be, a totem of the spider wasp. As spider wasps kill spiders, she escaped the astral world where she lived to find Spider-Man.
Shriek
Shriek (comics)
Shriek is a fictional character, a supervillainess in the Marvel Comics universe. She is an enemy of Spider-Man. She was created by Tom DeFalco, Mike W...

Spider-Man Unlimited #1 (May 1993) Shriek is a dangerous and criminally insane villainess with the ability to manipulate sound in a number of elaborate ways. She once allied herself with Carnage and several other supervillains who went about New York on a killing spree.

Shriek's origins and real name are uncertain. She was named Sandra Deel in her earliest appearances, but named Frances Louise Barrison in later appearances.
Sin-Eater
Sin-Eater (comics)
Sin-Eater is a name given to several fictional characters appearing in books published by Marvel Comics, usually those featuring Spider-Man and Ghost Rider.- Stanley Carter :...

 
Spectacular Spider-Man #107 (October 1985) Well known for his murder of Captain Jean DeWolff, Stanley Carter was injected with drugs while with S.H.I.E.L.D.
S.H.I.E.L.D.
S.H.I.E.L.D. is a fictional espionage and a secret military law-enforcement agency in the Marvel Comics Universe. Created by Stan Lee and Jack Kirby in Strange Tales #135 , it often deals with superhuman threats....

 and had his strength & endurance increased.
Speed Demon  Avengers vol. 1 #70 (November 1969) James Sanders first appears under the codename Whizzer, as a member of the Squadron Sinister. Several years after the Squadron Sinister disbands, James Sanders decides to return to crime in a new costume as the Speed Demon and battles Spider-Man.
Spidercide
Spidercide (comics)
Spidercide is a fictional character from the Marvel Universe, a clone of the super-hero Spider-Man.-Fictional character biography:During the Clone Saga, in addition to Ben Reilly, Kaine, Jack and Guardian another clone of Spider-Man was introduced, Spidercide...

 
Spectacular Spider-Man #222 (1995) During the Clone Saga
Clone Saga
The Clone Saga or Spider-Clone Saga was a major story arc in Marvel Comics which ran from 1994 to 1996 involving many clones of Spider-Man.The story is considered to be one of the most controversial Spider-Man stories ever told...

, in addition to Ben Reilly
Ben Reilly
Benjamin "Ben" Reilly is a fictional character in the . He is a clone of Peter Parker , and is prominent in the "Clone Saga" story arc...

 and Kaine
Kaine
Kaine is a fictional character, a Marvel Comics supervillain and antihero who serves as both an ally and an enemy of Spider-Man. He first appeared in Web of Spider-Man #119, and is the Jackal's first failed attempt at cloning Peter Parker...

, a third significant clone of Spider-Man was introduced: Spidercide. He died during a battle with Spider-Man, Ben, and Kaine. Scrier recovered his remains and reanimated him, granting him the ability to turn into other materials and shapes in the process.
Squid
Squid (comics)
Squid is the name of four Marvel Comics villains.-Squid II:The second Squid was a gangster and youngest member of the Scungili Crime Family who battled Spider-Woman.-Squid III:...

Peter Parker: Spider-Man vol. 2 #16 (2000) Don Callahan can shift between his human form and his mouthless squid-like form. Squid and his girlfriend Ms. Fortune battled Spider-Man on a rooftop, and several subsequent occasions.
Stegron
Stegron
Stegron the Dinosaur Man is a Marvel Comics super-villain, primarily an antagonist of Spider-Man.-Fictional character biography:Vincent Stegron was hired by S.H.I.E.L.D. to work with Dr. Curt Connors to study dinosaur DNA from the Savage Land. Obsessed with the experiments Connors did to create the...

Marvel Team-Up #19 (March 1974) Dr. Vincent Stegron was hired by S.H.I.E.L.D to assist Dr. Curt Connors in studying dinosaur DNA from the Savage Land
Savage Land
The Savage Land is a hidden prehistoric land within the fictional Marvel Comics Universe. It is a tropical preserve hidden in Antarctica. It was created by Stan Lee and Jack Kirby in X-Men #10...

. Obsessed with the experiments Connors did to create the Lizard
Lizard (comics)
The Lizard is a fictional character, a supervillain in the Marvel Comics universe and enemy of Spider-Man. The Lizard first appeared in The Amazing Spider-Man #6 , and was created by Stan Lee and Steve Ditko...

, Stegron stole the DNA samples and injected himself with them. He then transformed into a hominid dinosaur and became bent on reclaiming the earth for the dinosaurs.
Mendel Stromm Amazing Spider-Man #37 (June 1966) Stromm was Norman Osborn's college professor, and became his partner in OsCorp Industries. His early research was on a chemical that would provide enhanced strength in its test subjects (and would eventually turn Osborn into the Green Goblin). Osborn, wanting the formula for himself, discovered that Stromm had been embezzling funds from OsCorp, and turned Stromm over to the police. After several years in prison, Stromm was released and tried to kill Norman Osborn for revenge using evil robots. He was stopped by Spider-Man and seemingly died of a heart attack.

Stromm had made plans for his death, however, by arranging to have his brain waves transferred to a robot double. Now calling himself Robot Master, Stromm returned in Spectacular Spider-Man vol. 1, #68 (July 1982). After being defeated and destroyed, Stromm returned several times as a cyborg sometimes known as Gaunt.
Stunner
Stunner (comics)
Angelina Brancale is a supervillain in the Marvel Comics Universe. Originally an overweight and lonely receptionist working for Dr. Carolyn Trainer, she was given great strength and beauty through virtual reality technology and became the super-villain known as Stunner.-Fictional character...

Amazing Spider-Man #397 (January 1995) Angelina Brancale was the typical outcast in high school. As she grew older, she never expected to amount to anything, and grew increasingly depressed. Working as a secretary, she was chosen by Doctor Octopus to be the guinea pig for his new virtual reality invention. The test was a success, and Angelina mentally created Stunner, the beautiful, thin woman she always wished she was.
Styx and Stone
Styx and Stone
Styx and Stone are two fictional comic book characters in the Marvel Comics universe. They are a criminal duo that have crossed Spider-Man's path on a number of occasions. They were created by David Michelinie and Todd McFarlane and first appeared in The Amazing Spider-Man #309...

Amazing Spider-Man #309 (November, 1988) Gerald Stone was an idealistic scientist who wanted to find a cure for cancer. He conducted an illegal experiment on a homeless person named Jacob Eishorn. The experiment failed and Eishorn became a living cancer, who needed to kill to survive. Now calling himself "Styx", Eishorn enjoyed the killing of innocents. Feeling responsible for Styx, Stone built high-tech weaponry for himself and turned the two of them into a mercenary duo.
Tarantula
Tarantula (Marvel Comics)
Tarantula is the alias of a number of fictional characters appearing in publications from Marvel Comics.-Clay Riley:The Tarantula is a Zorro-like western-era villain equipped with a scourge and has a mysterious Mexican accent. He first appears in Ghost Rider #2 . He is the leader of the villainous...

 
Amazing Spider-Man #134 (July 1974) As a revolutionary terrorist and government operative, Anton Miguel Rodriguez is expelled from his small organization and went on to the other repressive side of the government where they created the identity of the Tarantula for him and to serve as his country's counterpart to Captain America
Captain America
Captain America is a fictional character, a superhero that appears in comic books published by Marvel Comics. The character first appeared in Captain America Comics #1 , from Marvel Comics' 1940s predecessor, Timely Comics, and was created by Joe Simon and Jack Kirby...

.
Tatterdemalion Werewolf by Night #9 (September 1973) Arnold Paffenroth was once a wealthy business investor until the Las Vegas mob swindled him out of all of his money. This resulted in him becoming an insane homeless person. At some point, the agency known as "Night Shift," outfitted Paffenroth with a sophisticated costume. Taking the name "Tatterdemalion" (a person dressed in ragged clothing), he snuck up on unsuspecting victims and proceeded to destroy their money, rather than steal it; an odd twist on mugging.
Thousand
Thousand (comics)
The Thousand is a fictional character, a comic book supervillain and enemy of Spider-Man in the . Created in combination by Garth Ennis, John McCrea and James Hodgkins, the character first appears in Tangled Web of Spider-Man #1....

Tangled Web of Spider-Man #1 Carl King became the Thousand when he devoured a dead radioactive spider, which resulted in his transformation from a human being into a hive-minded swarm of a thousand spiders. Discovering his power to consume the innards of other human beings and use their skin like a suit after accidentally doing so to his mother, King proceeds to do the same to his father and, wanting to gain mastery of his new abilities, begins to consume and take over the bodies of various people, most of them homeless vagrants and children.
Toro Negro ("Black Bull") Amazing Scarlet Spider #2 (December 1995) El Toro Negro is a South American mercenary and antagonist of Spider-Man
Spider-Man
Spider-Man is a fictional Marvel Comics superhero. The character was created by writer-editor Stan Lee and writer-artist Steve Ditko. He first appeared in Amazing Fantasy #15...

 closely associated with the Great Game. The mercenary has enhanced strength, speed, durability, and agility, as well as a large arsenal of weapons. The character along with his partner Polestar
Polestar (comics)
Polestar is the name used by a pair of mercenaries and antagonists of Spider-Man, closely associated with the Great Game. The first is currently deceased.-Polestar I:...

, kill the superhero Nightwatch
Nightwatch (comics)
Nightwatch is a fictional super hero who has appeared in various comic book series published by Marvel Comics. He exists in Marvel's main shared universe, known as the Marvel Universe.-Publication history:...

, and El Toro Negro follows by killing Polestar. He was last seen as a captive of his sponsor Justin Hammer
Justin Hammer
Justin Hammer is a fictional character that has appeared in various comic book series published by Marvel Comics. As a frequent adversary of the superhero Iron Man, Justin Hammer exists in Marvel's main shared universe, known as the Marvel Universe...

, who told him that he would remove Torres' weaknesses — starting with his mind. Hammer then proceeded to forcibly lobotomize the immobilized Torres.
Tracer
Tracer (Marvel Comics)
Tracer is a fictional character, a supervillain in the Marvel Comics Universe, in which he is an enemy of Spider-Man. His first appearance was in Friendly Neighborhood Spider-Man #1.-Fictional character biography:...

Friendly Neighborhood Spider-Man #1 (October 2005) Tracer claims to be a "machine god" that the artificial intelligences of other machines created to worship, alleging that he becomes stronger over time since the more machines worship him the longer he operates.
Seward Trainer Peter Parker: Spider-Man #52 Seward was the Jackal's trusty assistant and the Jackal couldn't have done all of his cloning without him.
Tri-Sentinel
Tri-Sentinel
The Tri-Sentinel is a fictional robot who has appeared in the superhero comics of Marvel Comics.-Acts of Vengeance:The Tri-Sentinel's first appearance was in Amazing Spider-Man #329, which followed on directly from the Acts of Vengeance storyline...

 
Amazing Spider-Man #329 (October 1990) Three Sentinels
Sentinel (comics)
Sentinels are a fictional variety of mutant-hunting robots, appearing in the Marvel Comics Universe. They are usually portrayed as antagonists to the X-Men. Created by Stan Lee and Jack Kirby, they first appeared in The X-Men #14 .According to Marvel canon, Sentinels are programmed to locate...

 combined into one giant robot whose goal is to eliminate Spider-Man.
Vermin
Vermin (comics)
Vermin is a fictional character, a comic book supervillain in the Marvel Comics universe. The character's first appearance was in Captain America #272 .-Fictional character biography:...

Captain America #272 (August, 1982) Edward Whelan was genetically altered by Arnim Zola
Arnim Zola
Arnim Zola is a fictional character a supervillain appearing in the Marvel Comics universe. He is a master of biochemistry, and frequent foe of Captain America and the Avengers.-Publication history:...

, who was in league with the second Baron Zemo
Baron Zemo
Baron Zemo is the name of two fictional characters, both supervillains, in various Marvel Comics comic books, notably Captain America and the Avengers...

, as part of a failed plot to destroy their mutual foe, Captain America
Captain America
Captain America is a fictional character, a superhero that appears in comic books published by Marvel Comics. The character first appeared in Captain America Comics #1 , from Marvel Comics' 1940s predecessor, Timely Comics, and was created by Joe Simon and Jack Kirby...

. He later went on to battle the combined forces of Captain America and Spider-Man, the latter of whom needed help from Captain America to defeat him. In order to prove his superiority over his hated foe in the Kraven's Last Hunt
Kraven's Last Hunt
"Kraven's Last Hunt" is a comic book storyline by J.M. DeMatteis and Mike Zeck published in 1987, featuring the final battle between Marvel Comics characters Kraven the Hunter and Spider-Man...

 storyline, Kraven the Hunter
Kraven the Hunter
Kraven the Hunter is a fictional character, a supervillain and enemy of Spider-Man appearing in comic books published by Marvel Comics. Kraven's name is Sergei Kravinoff. He also appears as Xraven, with white-grey skin and red eyes, possessing the powers of X-Men. He is the half-brother of Dmitri...

 (who was impersonating Spider-Man in a version of his black costume) went on to personally confront Vermin and single-handedly defeated him. After Spider-Man freed himself from a coffin which Kraven buried six feet under, Kraven released Vermin so Spider-Man would be forced to chase after him in order to prevent him from harming anyone. It was then that Kraven took the opportunity to end his own life. Vermin went on to menace Spider-Man a number of times since being recaptured, as well as frequently being an inmate at the Ravencroft Institute for the Criminally Insane.
Will o' the Wisp
Will o' the Wisp (comics)
Will o' the Wisp is a fictional character, a comic book supervillain in the Marvel Universe. He is a physicist who gained control over the electromagnetic attraction between his body's molecules, allowing him to adjust his density...

 
Amazing Spider-Man #167 (April 1977) Jackson Arvad was a scientist who specialized in electromagnetic research. He was working late one night, and caused an accident as he was so tired. A gravimetric power surge made him plunge into a self-sustaining magnetic field, causing Arvad's molecules to gradually disperse. He gained ghostly powers and became one of Spider-Man's eeriest enemies.
White Rabbit
White Rabbit (comics)
The White Rabbit is a supervillainess in the Marvel Universe and is an enemy of Spider-Man . She first appeared in Marvel Team-Up #131 in July 1983, and was created by J.M...

Marvel Team-Up #131 (July, 1983) Lorina Dodson, a criminal robbing various fast food joints, most notably "Kwikkee Burgers," armed with a giant heavily armed robotic rabbit, genetically altered killer bunny rabbits, an umbrella that fires explosive and razor tipped carrots, and a pair of rocket boots.
Wraith
Wraith (Marvel Comics)
Wraith is the name of four unrelated fictional characters from the Marvel Comics universe.-Brian DeWolff:The Wraith is a fictional character, owned by Marvel Comics and existing in that company's Marvel Universe...

Marvel Team-Up #48 (August 1976) Brian DeWolff was a former patrolman for the New York Police Department, who was shot by criminals and rescued by his father, using experimental technologies to restore Brian's health. This process gave Brian psionic abilities, including the ability to read minds, induce illusions in the minds of others, project psionic force bolts, and control the mind of another person (but he can only control one mind at a time), but left him with no mind of his own and susceptible to the mental domination of others.

Group villains

Villain First appearance Description
Enforcers
Enforcers (comics)
The Enforcers are a fictional team of villains in the Marvel Comics universe. Created by writer-editor Stan Lee and artist and co-plotter Steve Ditko, the team's first appearance was in The Amazing Spider-Man #10 .-Publication history:...

 
Amazing Spider-Man #10 (March 1964) The Enforcers came together to combine their forces and become a very powerful band of criminals that has been very much in demand by many criminal leaders over the years, first by the Big Man, Frederick Foswell. Its members are self trained as none have superhuman
Superhuman
Superhuman can mean an improved human, for example, by genetic modification, cybernetic implants, or as what humans might evolve into, in the near or distant future...

 powers. The Enforcers mainly consists of Montana
Montana (comics)
Montana is a fictional character in the Marvel Universe.-Publication history:Montana first appeared in The Amazing Spider-Man #10 , and was created by Stan Lee and Steve Ditko....

, Ox
Ox (comics)
Ox is a fictional Marvel Comics supervillain, and he usually works for the Kingpin, Mister Fear or Hammerhead.-Publication history:The original Ox, Raymond Bloch, first appeared in The Amazing Spider-Man #10 , and was created by Stan Lee and Steve Ditko...

, and Fancy Dan
Fancy Dan
Fancy Dan is a fictional character in the Marvel Universe.-Publication history:Fancy Dan first appeared in The Amazing Spider-Man #10 , and was created by Stan Lee and Steve Ditko....

.
Exterminators Sensational Spider-Man vol. 2 #29 (March 2003) The Exterminators is a group led by the Chameleon
Chameleon (comics)
The Chameleon is a fictional character that appears in comic books published by Marvel Comics. The character first appears in The Amazing Spider-Man #1 , and was created by writer Stan Lee and artist Steve Ditko; the Chameleon is the first member of Spider-Man's rogues' gallery, based on issue...

 to hunt down Peter Parker and his loved ones. It consisted of Molten Man
Molten Man
Molten Man is a fictional character, a supervillain in the Marvel Universe. The character was created by Stan Lee and Steve Ditko and first appeared in The Amazing Spider-Man #28 .-Fictional character biography:...

, Will o' the Wisp
Will o' the Wisp (comics)
Will o' the Wisp is a fictional character, a comic book supervillain in the Marvel Universe. He is a physicist who gained control over the electromagnetic attraction between his body's molecules, allowing him to adjust his density...

, Rhino
Rhino (comics)
The Rhino is a fictional character that appears in comic books published by Marvel Comics. Created by writer Stan Lee and artist John Romita, Sr., the character first appeared in The Amazing Spider-Man #41 The Rhino (Aleksei Mikhailovich Sytsevich) is a fictional character that appears in comic...

, Swarm
Swarm (comics)
Swarm is a fictional character and supervillain, an enemy of Spider-Man in the Marvel Comics universe. A former Nazi sympathizer, his most notable physical feature is that his entire body is composed of bees....

, Scarecrow
Scarecrow (Marvel Comics)
The Scarecrow is a fictional character, a supervillain in the Marvel Comics Universe, in which he is an enemy of Captain America, Spider-Man, Ghost Rider, and Iron Man. His first appearance was in Tales of Suspense #51....

, and Electro.
Femme Fatals
Femme Fatales (comics)
The Femme Fatales are a fictional group of female characters owned by Marvel Comics and antagonists to the superhero character Spider-Man.-Fictional history:In the comic book series the females are villains and mutants that serve as mercenaries for hire...

 
Amazing Spider-Man #340 (October 1990) A group of deadly superpowered females.
Jury
The Jury (comics)
The Jury is a fictional group of armored vigilantes in the Marvel Comics universe. The team was first introduced in Venom: Lethal Protector #2.-History:...

 
Amazing Spider-Man #383 The group first appears in Venom: Lethal Protector and consists of Sentry
Curtis Elkins
Sentry is a member of The Jury in the fictional Marvel comic universe. His rank is commanding officer. His ethnicity is African-American.-Fictional character biography:...

, Ramshot
Ramshot
Samuel Caulkin aka Ramshot is a fictional character in the Marvel comics universe.-Fictional character biography:Ramshot is a member of an armored group of vigilantes dubbed The Jury. Caulkin was recruited into the Jury by General Orwell Taylor to help him avenge the death of his youngest son Hugh....

, Screech
Screech (comics)
For other uses of the word Screech, see Screech .Maxwell "Max" Taylor aka Screech is a fictional character in the Marvel Comics universe.-Fictional character biography:...

, Bomblast
Bomblast
Bomblast is a fictional character in the Marvel comics universe. He is a member of the The Jury.-Fictional character biography:Parmenter was recruited into the Jury by General Orwell Taylor after the death of the General's son Hugh who worked as a Guardsman at the Vault with Parmenter.Not much is...

, Firearm
Firearm (Marvel Comics)
Firearm is a fictional character, owned by Marvel Comics who exists in that company's Marvel Universe. He is a member of The Jury.-Fictional character biography:...

, Wysper
Wysper
Wysper is a fictional character in the Marvel Comics universe. She first appeared Venom: Lethal Protector #2 and was created by Dan Slott and John Calimee.-Fictional character biography:...

, and U.S. Agent
U.S. Agent
U.S. Agent is a fictional comic book superhero appearing in books published by Marvel Comics, usually those starring Captain America and the Avengers. He was created by Mark Gruenwald and Paul Neary in Captain America vol...

.
Sinister Six
Sinister Six
The Sinister Six are a group of supervillains in the Marvel Comics universe, drawn from Spider-Man's rogues gallery. The original incarnation of the group was organized by Doctor Octopus, and first appeared in The Amazing Spider-Man Annual #1 ....

 
Amazing Spider-Man Annual #1 (1964) The Sinister Six is formed by Doc Ock, one of Spider-Man's major enemies. He thought if Spider-Man's six greatest villains join together they can defeat the web-slinger, so he hunts down 5 others: Vulture, Electro, Sandman, Mysterio, and Kraven the Hunter. He organizes a plan for each to attack Spider-Man one by one until Spider-Man is defeated. They kidnapp Betty Brant
Betty Brant
Elizabeth "Betty" Brant is a supporting character in Marvel Comics’s Spider-Man series. Created by writer Stan Lee and artist Steve Ditko, she first appeared in The Amazing Spider-Man #4 .-Fictional character biography:...

 and Aunt May
Aunt May
May Reilly Parker-Jameson, commonly known as Aunt May, is a supporting character in Marvel Comics' Spider-Man series. Created by writer Stan Lee and artist Steve Ditko, she first appeared as May Parker in Amazing Fantasy #15...

 to make Spider-Man fight. Spider-Man defeats the six villains one by one until they are all defeated. The group reforms many times with varying membership and various numbers including Sinister Seven and Sinister Twelve, though the Vulture and Electro have been in most incarnations.
Sinister Syndicate
Sinister Syndicate
The Sinister Syndicate is a group of supervillains in the Marvel Comics universe, who serve as a collection of lesser-known Spider-Man's villains...

 
Amazing Spider-Man #280 Patterned after the conglomeration of Spider-Man's deadliest foes who call themselves the Sinister Six, the Sinister Syndicate originally is formed by the supervillain Abe Jenkins, aka "The Beetle". The original roster of the group consisted of Beetle, Hydro-Man, Rhino, Boomerang, and Speed Demon, who collectively gathered together under the Beetle's leadership. The Shocker was later added to the group.
"Carnage Family" Spider-Man Unlimited #1 After being defeated several times, Carnage
Carnage (comics)
Carnage is a fictional character, a supervillain in the . The character first appears in The Amazing Spider-Man #344 , and was created by writer David Michelinie and artist Mark Bagley. The character is frequently depicted as an enemy of Spider-Man...

 formed a group of phsycotic supervillains, Shriek, Doppleganger, Demogoblin, and Carrion (Malcom McBride). The team wass featured prominently in the 1990's arc,Maximum Carnage
Maximum Carnage
"Maximum Carnage" is a fourteen-part comic book crossover published in Marvel Comics's Spider-Man family of titles in 1993. It featured Spider-Man and Venom teaming up to face Venom's murderous offspring Carnage.-Plot:...

, and later in the 2010 storyline, Carnage.

In other media

There are plenty of Spider-Man villains that have gone outside the comic book genre and have been seen in media such as television, film, and video games. Some have been made specifically for TV. Most of Spider-Man's greatest enemies in the comics like the ones in the Central Rogues gallery as seen above have been adopted in most of Spider-Man media
Spider-Man in other media
Spider-Man is a fictional comic book character who has been adapted in various other media.-Official appearances:Spider-Man has been adapted to television many times, as a short-lived live-action television series, a Japanese tokusatsu series, and several animated cartoon series...

 or other Marvel Comics
Marvel Comics
Marvel Worldwide, Inc., commonly referred to as Marvel Comics and formerly Marvel Publishing, Inc. and Marvel Comics Group, is an American company that publishes comic books and related media...

related shows.

External links

The source of this article is wikipedia, the free encyclopedia.  The text of this article is licensed under the GFDL.
 
x
OK