Lipotropic
Encyclopedia
Lipotropic compounds are those that help catalyse the breakdown of fat
Fat
Fats consist of a wide group of compounds that are generally soluble in organic solvents and generally insoluble in water. Chemically, fats are triglycerides, triesters of glycerol and any of several fatty acids. Fats may be either solid or liquid at room temperature, depending on their structure...

 during metabolism
Metabolism
Metabolism is the set of chemical reactions that happen in the cells of living organisms to sustain life. These processes allow organisms to grow and reproduce, maintain their structures, and respond to their environments. Metabolism is usually divided into two categories...

 in the body.

Choline
Choline
Choline is a water-soluble essential nutrient. It is usually grouped within the B-complex vitamins. Choline generally refers to the various quaternary ammonium salts containing the N,N,N-trimethylethanolammonium cation....

is the major lipotrope in mammals and other known lipotropes are important only insofar as they contribute to the synthesis of choline. (Barak, 1973)

A lipotropic nutrient promotes or encourages the export of fat from the liver. Lipotropics are necessary for maintenance of a healthy liver, and for burning the exported fat for additional energy. Without lipotropics, such as choline and inositol, fats and bile can become trapped in the liver, causing severe problems such as cirrhosis and blocking fat metabolism. Choline is essential for fat metabolism. Choline functions as a methyl donor and it is required for proper liver function. Like inositol, choline is a lipotropic. Inositol exerts lipotropic effects as well. An "unofficial" member of the B vitamins, inositol has even been shown to relieve depression and panic attacks.
Methionine, an essential amino acid, is the major lipotropic compound in humans. When estrogen levels are high, the body requires more methionine. Estrogens reduce bile flow through the liver and increase bile cholesterol levels. Methionine helps deactivate estrogens.

Methionine levels also affect the amount of sulfur-containing compounds, such as glutathione, in the liver. Glutathione and other sulfur-containing peptides (small proteins) play a critical role in defending against toxic compounds. When higher levels of toxic compounds are present, more methionine is needed.

Choline assists detoxification reactions in the liver. Though choline can be synthesized from methionine or serine, recent evidence indicates that choline is an essential nutrient.

Betaine hydrochloride is a powerful lipotropic and increases gastric acid.
The source of this article is wikipedia, the free encyclopedia.  The text of this article is licensed under the GFDL.
 
x
OK