Lawrence S.B. Goldstein
Encyclopedia
Lawrence S.B. Goldstein (born Buffalo, New York; February 20, 1956) is a professor of cellular and molecular medicine at University of California, San Diego
and investigator with the Howard Hughes Medical Institute
. He receives grant funding from the NIH, the Johns Hopkins ALS Center, the HighQ Foundation, and the California Institute for Regenerative Medicine
.
from 1980–1983 and the Massachusetts Institute of Technology
in 1983/1984. He was Assistant, Associate and Full Professor at Harvard University
in the Department of Cellular and Developmental Biology from 1984–1993 and moved to UCSD and HHMI in 1993. His awards include a Senior Scholar Award from the Ellison Medical Foundation, an American Cancer Society
Faculty Research Award, and the Loeb Chair in Natural Sciences when he was at Harvard University.
His research is focused on understanding the molecular mechanisms of intracellular movement in neurons and the role of transport failures in neurodegenerative diseases. His lab provided the first molecular descriptions of kinesin
structure and organization, and also discovered important links between transport processes and diseases such as Alzheimer's Disease
and Huntington's Disease
. Dr. Goldstein has also had an active role in National Science policy. He has served on many public science advisory committees, has written about, spoken about, and been interviewed on numerous occasions on science issues by print and broadcast media, and has testified on a number of occasions in the U.S. House of Representatives and the Senate about NIH funding and stem cell research. As a cofounder and consultant of the biotechnology company Cytokinetics, Inc. he has also had an active role in private industry. Goldstein has also served as elected secretary of the American Society for Cell Biology (ASCB).
University of California, San Diego
The University of California, San Diego, commonly known as UCSD or UC San Diego, is a public research university located in the La Jolla neighborhood of San Diego, California, United States...
and investigator with the Howard Hughes Medical Institute
Howard Hughes Medical Institute
Howard Hughes Medical Institute is a United States non-profit medical research organization based in Chevy Chase, Maryland. It was founded by the American businessman Howard Hughes in 1953. It is one of the largest private funding organizations for biological and medical research in the United...
. He receives grant funding from the NIH, the Johns Hopkins ALS Center, the HighQ Foundation, and the California Institute for Regenerative Medicine
California Institute for Regenerative Medicine
The California Institute for Regenerative Medicine was created by California's Proposition 71 , which authorized it to issue $3 billion in grants, funded by bonds, over ten years for embryonic stem cell and other biomedical research. It is claimed to be the world's largest single backer of...
.
Biography
Dr. Goldstein received his B.A. degree in biology and genetics from UCSD in 1976 and his Ph.D. degree in genetics from the University of Washington, Seattle in 1980. He did postdoctoral research at the University of Colorado at BoulderUniversity of Colorado at Boulder
The University of Colorado Boulder is a public research university located in Boulder, Colorado...
from 1980–1983 and the Massachusetts Institute of Technology
Massachusetts Institute of Technology
The Massachusetts Institute of Technology is a private research university located in Cambridge, Massachusetts. MIT has five schools and one college, containing a total of 32 academic departments, with a strong emphasis on scientific and technological education and research.Founded in 1861 in...
in 1983/1984. He was Assistant, Associate and Full Professor at Harvard University
Harvard University
Harvard University is a private Ivy League university located in Cambridge, Massachusetts, United States, established in 1636 by the Massachusetts legislature. Harvard is the oldest institution of higher learning in the United States and the first corporation chartered in the country...
in the Department of Cellular and Developmental Biology from 1984–1993 and moved to UCSD and HHMI in 1993. His awards include a Senior Scholar Award from the Ellison Medical Foundation, an American Cancer Society
American Cancer Society
The American Cancer Society is the "nationwide community-based voluntary health organization" dedicated, in their own words, "to eliminating cancer as a major health problem by preventing cancer, saving lives, and diminishing suffering from cancer, through research, education, advocacy, and...
Faculty Research Award, and the Loeb Chair in Natural Sciences when he was at Harvard University.
His research is focused on understanding the molecular mechanisms of intracellular movement in neurons and the role of transport failures in neurodegenerative diseases. His lab provided the first molecular descriptions of kinesin
Kinesin
A kinesin is a protein belonging to a class of motor proteins found in eukaryotic cells. Kinesins move along microtubule filaments, and are powered by the hydrolysis of ATP . The active movement of kinesins supports several cellular functions including mitosis, meiosis and transport of cellular...
structure and organization, and also discovered important links between transport processes and diseases such as Alzheimer's Disease
Alzheimer's disease
Alzheimer's disease also known in medical literature as Alzheimer disease is the most common form of dementia. There is no cure for the disease, which worsens as it progresses, and eventually leads to death...
and Huntington's Disease
Huntington's disease
Huntington's disease, chorea, or disorder , is a neurodegenerative genetic disorder that affects muscle coordination and leads to cognitive decline and dementia. It typically becomes noticeable in middle age. HD is the most common genetic cause of abnormal involuntary writhing movements called chorea...
. Dr. Goldstein has also had an active role in National Science policy. He has served on many public science advisory committees, has written about, spoken about, and been interviewed on numerous occasions on science issues by print and broadcast media, and has testified on a number of occasions in the U.S. House of Representatives and the Senate about NIH funding and stem cell research. As a cofounder and consultant of the biotechnology company Cytokinetics, Inc. he has also had an active role in private industry. Goldstein has also served as elected secretary of the American Society for Cell Biology (ASCB).