James Fallon
Encyclopedia
Academics
He received his biology and chemistry undergraduate training at Saint Michael's College in Vermont and his psychologyPsychology
Psychology is the study of the mind and behavior. Its immediate goal is to understand individuals and groups by both establishing general principles and researching specific cases. For many, the ultimate goal of psychology is to benefit society...
and psychophysics
Psychophysics
Psychophysics quantitatively investigates the relationship between physical stimuli and the sensations and perceptions they effect. Psychophysics has been described as "the scientific study of the relation between stimulus and sensation" or, more completely, as "the analysis of perceptual...
degree at Rensselaer Polytechnic Institute
Rensselaer Polytechnic Institute
Stephen Van Rensselaer established the Rensselaer School on November 5, 1824 with a letter to the Rev. Dr. Samuel Blatchford, in which van Rensselaer asked Blatchford to serve as the first president. Within the letter he set down several orders of business. He appointed Amos Eaton as the school's...
in New York. He carried out his Ph.D. training in neuroanatomy
Neuroanatomy
Neuroanatomy is the study of the anatomy and organization of the nervous system. In contrast to animals with radial symmetry, whose nervous system consists of a distributed network of cells, animals with bilateral symmetry have segregated, defined nervous systems, and thus we can begin to speak of...
and neurophysiology
Neurophysiology
Neurophysiology is a part of physiology. Neurophysiology is the study of nervous system function...
at the University of Illinois College of Medicine
University of Illinois College of Medicine
The University of Illinois College of Medicine offers a four-year program leading to the MD degree at four different sites in Illinois: Chicago, Peoria, Rockford, and Urbana–Champaign....
, and his postdoctoral training in chemical neuroanatomy
Neuroanatomy
Neuroanatomy is the study of the anatomy and organization of the nervous system. In contrast to animals with radial symmetry, whose nervous system consists of a distributed network of cells, animals with bilateral symmetry have segregated, defined nervous systems, and thus we can begin to speak of...
at UC San Diego. He is Professor of Anatomy and Neurobiology at UC Irvine where he has served as Chairman of the University faculty and Chair and President of the School of Medicine faculty. He is a Sloan Scholar, Senior Fulbright Fellow, National Institutes of Health Career Awardee, and recipient of a range of honorary degrees, awards, and sits on several corporate boards and national think tanks for science, biotechnology, the arts, and the US military. He is a Subject Matter Expert in the field of "cognition and war" to the Pentagon's Joint Command.
Fallon has made significant scientific contributions in several neuroscientific subjects, including discoveries of TGF alpha
TGF alpha
Transforming growth factor alpha is upregulated in some human cancers. It is produced in macrophages, brain cells, and keratinocytes, and induces epithelial development. It is closely related to EGF, and can also bind to the EGF receptor with similar effects...
, epidermal growth factor
Epidermal growth factor
Epidermal growth factor or EGF is a growth factor that plays an important role in the regulation of cell growth, proliferation, and differentiation by binding to its receptor EGFR...
, and the first to show large-scale stimulation adult stem cells in the injured brain using growth factors. He has also made contributions in the fields of schizophrenia
Schizophrenia
Schizophrenia is a mental disorder characterized by a disintegration of thought processes and of emotional responsiveness. It most commonly manifests itself as auditory hallucinations, paranoid or bizarre delusions, or disorganized speech and thinking, and it is accompanied by significant social...
, Parkinson's disease
Parkinson's disease
Parkinson's disease is a degenerative disorder of the central nervous system...
, Alzheimer's disease
Alzheimer's disease
Alzheimer's disease also known in medical literature as Alzheimer disease is the most common form of dementia. There is no cure for the disease, which worsens as it progresses, and eventually leads to death...
, and the roles of hostility and gender in nicotine
Nicotine
Nicotine is an alkaloid found in the nightshade family of plants that constitutes approximately 0.6–3.0% of the dry weight of tobacco, with biosynthesis taking place in the roots and accumulation occurring in the leaves...
and cocaine
Cocaine
Cocaine is a crystalline tropane alkaloid that is obtained from the leaves of the coca plant. The name comes from "coca" in addition to the alkaloid suffix -ine, forming cocaine. It is a stimulant of the central nervous system, an appetite suppressant, and a topical anesthetic...
addiction
Substance dependence
The section about substance dependence in the Diagnostic and Statistical Manual of Mental Disorders does not use the word addiction at all. It explains:...
. He is also cited for his research in the basic biology of dopamine, norepinephrine, opioid peptides in the brain, connections of the cortex, limbic system
Limbic system
The limbic system is a set of brain structures including the hippocampus, amygdala, anterior thalamic nuclei, septum, limbic cortex and fornix, which seemingly support a variety of functions including emotion, behavior, long term memory, and olfaction. The term "limbic" comes from the Latin...
, and basal ganglia
Basal ganglia
The basal ganglia are a group of nuclei of varied origin in the brains of vertebrates that act as a cohesive functional unit. They are situated at the base of the forebrain and are strongly connected with the cerebral cortex, thalamus and other brain areas...
in animals and humans. He has published in human brain imaging using positron emission tomography, magnetic resonance imaging
Magnetic resonance imaging
Magnetic resonance imaging , nuclear magnetic resonance imaging , or magnetic resonance tomography is a medical imaging technique used in radiology to visualize detailed internal structures...
, diffusion tensor imaging tractography
Tractography
In neuroscience, tractography is a procedure to demonstrate the neural tracts.It uses special techniques of magnetic resonance imaging , and computer-based image analysis.The results are presented in two- and three-dimensional images....
techniques, and the new field of imaging genetics.
Other work
In addition to his neuroscience research, James Fallon has lectured and written on topics ranging from art and the brain, architecture and the brain, law and the brain, consciousnessConsciousness
Consciousness is a term that refers to the relationship between the mind and the world with which it interacts. It has been defined as: subjectivity, awareness, the ability to experience or to feel, wakefulness, having a sense of selfhood, and the executive control system of the mind...
, creativity, the brain of the psychopathic murderer, and the Vietnam War.
He has appeared on numerous documentaries, radio, and TV shows. From 2007 to 2009, he appeared on the History Channel series on science and technology (Star Wars Tech, Spider-Man Tech), CNN, PBS, BBC, and ABC for his work on stem cells, growth factors, psychopathology, tissue engineering, smart prostheses, schizophrenia, and human and animal behavior and disease. On November 18, 2009 he appeared as himself on the CBS crime drama series Criminal Minds
Criminal Minds
Criminal Minds is an American police procedural drama that premiered September 22, 2005, on CBS. The series follows a team of profilers from the FBI's Behavioral Analysis Unit based in Quantico, Virginia. The BAU is part of the FBI National Center for the Analysis of Violent Crime...
, which explores his theory of trans-generational violence in areas of the world that experience continuous bouts of terrorism, war, and violence. In a related story, Dr. Fallon and his family underwent functional brain imaging and genetic analyses for potential violence related brain and genetic patterns, as reported in the November 27th, 2009 edition of the Wall Street Journal.
Fallon prominently featured in the BBC production Are You Good or Evil?, where he is revealed to have discovered that he, himself, has the neurological and genetic correlates of psychopathy
Psychopathy
Psychopathy is a mental disorder characterized primarily by a lack of empathy and remorse, shallow emotions, egocentricity, and deceptiveness. Psychopaths are highly prone to antisocial behavior and abusive treatment of others, and are very disproportionately responsible for violent crime...
. Fallon stated that he is not concerned by the findings and believes that his positive experiences in childhood negated any potential genetic vulnerabilities to violence and emotional issues.