Iraqi biological weapons program
Encyclopedia
Saddam Hussein
Saddam Hussein
Saddam Hussein Abd al-Majid al-Tikriti was the fifth President of Iraq, serving in this capacity from 16 July 1979 until 9 April 2003...

 (1937-2006) initiated an extensive biological weapons (BW) program in Iraq
Iraq
Iraq ; officially the Republic of Iraq is a country in Western Asia spanning most of the northwestern end of the Zagros mountain range, the eastern part of the Syrian Desert and the northern part of the Arabian Desert....

in the early 1980s, in violation of the Biological Weapons Convention
Biological Weapons Convention
The Convention on the Prohibition of the Development, Production and Stockpiling of Bacteriological and Toxin Weapons and on their Destruction was the first multilateral disarmament treaty banning the...

 (BWC) of 1972. Details of the BW program — along with a chemical weapons program — surfaced only in the wake of the Gulf War
Gulf War
The Persian Gulf War , commonly referred to as simply the Gulf War, was a war waged by a U.N.-authorized coalition force from 34 nations led by the United States, against Iraq in response to Iraq's invasion and annexation of Kuwait.The war is also known under other names, such as the First Gulf...

 (1990–91) following investigations conducted by the United Nations Special Commission
United Nations Special Commission
United Nations Special Commission was an inspection regime created by the United Nations to ensure Iraq's compliance with policies concerning Iraqi production and use of weapons of mass destruction after the Gulf War...

 (UNSCOM) which had been charged with the post-war disarmament of Saddam's Iraq. Because of this UN disarmament program, more is known today about the once-secret bioweapons program in Iraq than that of any other nation.

Startup and foreign suppliers

In the early 1980s, five German firms supplied equipment to manufacture botulin toxin and mycotoxin
Mycotoxin
A mycotoxin is a toxic secondary metabolite produced by organisms of the fungus kingdom, commonly known as molds. The term ‘mycotoxin’ is usually reserved for the toxic chemical products produced by fungi that readily colonize crops...

 to Iraq. Iraq's State Establishment for Pesticide Production (SEPP) also ordered culture media and incubators from Germany's Water Engineering Trading. Strains of dual-use biological material from France also helped advance Iraq’s biological warfare program. From the United States, the non-profit American Type Culture Collection
American Type Culture Collection
The American Type Culture Collection is a private, not-for-profit biological resource center whose mission focuses on the acquisition, authentication, production, preservation, development and distribution of standard reference microorganisms, cell lines and other materials for research in the...

 and the U.S. Centers for Disease Control sold or sent biological samples to Iraq up until 1989, which Iraq claimed to need for medical research. These materials included anthrax
Anthrax
Anthrax is an acute disease caused by the bacterium Bacillus anthracis. Most forms of the disease are lethal, and it affects both humans and other animals...

, West Nile virus
West Nile virus
West Nile virus is a virus of the family Flaviviridae. Part of the Japanese encephalitis antigenic complex of viruses, it is found in both tropical and temperate regions. It mainly infects birds, but is known to infect humans, horses, dogs, cats, bats, chipmunks, skunks, squirrels, domestic...

 and botulism
Botulism
Botulism also known as botulinus intoxication is a rare but serious paralytic illness caused by botulinum toxin which is metabolic waste produced under anaerobic conditions by the bacterium Clostridium botulinum, and affecting a wide range of mammals, birds and fish...

, as well as Brucella melitensis
Brucella melitensis
-Introduction:Brucella melitensis is a gram negative coccobacillus bacteria from the Brucellaceae family. The bacterium causes Ovine Brucellosis, along with Brucella ovis. It can infect sheep, cattle, and sometimes humans and it can be transmitted by the stable fly...

, and Clostridium perfringens
Clostridium perfringens
Clostridium perfringens is a Gram-positive, rod-shaped, anaerobic, spore-forming bacterium of the genus Clostridium. C. perfringens is ever present in nature and can be found as a normal component of decaying vegetation, marine sediment, the intestinal tract of humans and other vertebrates,...

. Some of these materials were used for Iraq's biological weapons research program, while others were used for vaccine development.
In delivering these materials "The CDC was abiding by World Health Organization guidelines that encouraged the free exchange of biological samples among medical researchers..." according to Thomas Monath, CDC lab director. It was a request "which we were obligated to fulfill," as described in WHO and UN treaties.

Facilities, agents and production

Iraq's BW facilities included its main biowarfare research center at Salman Pak
Salman Pak facility
The Salman Pak, or al-Salman, facility is an Iraqi military facility near Baghdad. At one time, it was a key center of Iraq’s biological and chemical weapons programs.-Background:...

 (just south of Baghdad
Baghdad
Baghdad is the capital of Iraq, as well as the coterminous Baghdad Governorate. The population of Baghdad in 2011 is approximately 7,216,040...

), the main bioweapons production facility at Al Hakum
Al Hakum (Iraq)
Al Hakum — also spelled Al Hakm, Al Hakem or Al Hakam — was at one time Iraq's most sophisticated and largest biological weapons production factory. The facility was part of a large military complex at Jurf Al Sakhar , about 60-70 kilometers southwest of Baghdad, near al-Musayyib...

 (the "Single-Cell Protein Production Plant") and the viral
Virus
A virus is a small infectious agent that can replicate only inside the living cells of organisms. Viruses infect all types of organisms, from animals and plants to bacteria and archaea...

 biowarfare research site at Al Manal (the "Foot and Mouth Disease Center").

The Al Hakum facility began mass production of weapons-grade anthrax
Anthrax
Anthrax is an acute disease caused by the bacterium Bacillus anthracis. Most forms of the disease are lethal, and it affects both humans and other animals...

 in 1989, eventually producing 8,000 liters or more (the 8,000 liter figure is based on declared amounts). Iraq officially acknowledged that it had worked with several species of bacterial pathogen, including Bacillus anthracis
Bacillus anthracis
Bacillus anthracis is the pathogen of the Anthrax acute disease. It is a Gram-positive, spore-forming, rod-shaped bacterium, with a width of 1-1.2µm and a length of 3-5µm. It can be grown in an ordinary nutrient medium under aerobic or anaerobic conditions.It is one of few bacteria known to...

, Clostridium botulinum
Clostridium botulinum
Clostridium botulinum is a Gram-positive, rod-shaped bacterium that produces several toxins. The best known are its neurotoxins, subdivided in types A-G, that cause the flaccid muscular paralysis seen in botulism. It is also the main paralytic agent in botox. C. botulinum is an anaerobic...

and Clostridium perfringens
Clostridium perfringens
Clostridium perfringens is a Gram-positive, rod-shaped, anaerobic, spore-forming bacterium of the genus Clostridium. C. perfringens is ever present in nature and can be found as a normal component of decaying vegetation, marine sediment, the intestinal tract of humans and other vertebrates,...

(gas gangrene
Gas gangrene
Gas gangrene is a bacterial infection that produces gas tissues in gangrene. It is a deadly form of gangrene usually caused by Clostridium perfringens bacteria. It is a medical emergency....

) and several viruses (including enterovirus 17 [human conjunctivitis
Conjunctivitis
Conjunctivitis refers to inflammation of the conjunctiva...

], rotavirus
Rotavirus
Rotavirus is the most common cause of severe diarrhoea among infants and young children, and is one of several viruses that cause infections often called stomach flu, despite having no relation to influenza. It is a genus of double-stranded RNA virus in the family Reoviridae. By the age of five,...

 and camelpox
Camelpox
Camelpox is a disease of camels caused by a virus of the family Poxviridae and the genus Orthopoxvirus. It causes skin lesions and a generalized infection. Fatality rates may approach 25 percent in epidemics in young camels, but other cases are generally mild. The infection may be spread to the...

). The program also purified biological toxins, such as botulinum toxin
Botulinum toxin
Botulinum toxin is a protein produced by the bacterium Clostridium botulinum, and is considered the most powerful neurotoxin ever discovered. Botulinum toxin causes Botulism poisoning, a serious and life-threatening illness in humans and animals...

, ricin
Ricin
Ricin , from the castor oil plant Ricinus communis, is a highly toxic, naturally occurring protein. A dose as small as a few grains of salt can kill an adult. The LD50 of ricin is around 22 micrograms per kilogram Ricin , from the castor oil plant Ricinus communis, is a highly toxic, naturally...

 and aflatoxin
Aflatoxin
Aflatoxins are naturally occurring mycotoxins that are produced by many species of Aspergillus, a fungus, the most notable ones being Aspergillus flavus and Aspergillus parasiticus. Aflatoxins are toxic and among the most carcinogenic substances known...

. After 1995, it was learned that, in all, Iraq had produced 19,000 liters of concentrated botulinum toxin (nearly 10,000 liters filled into munitions), 8,500 liters of concentrated anthrax (6,500 liters filled into munitions) and 2,200 liters of aflatoxin (1,580 liters filled into munitions). In total, the program grew a half million liters of biological agents.

1991 US response

During the Gulf War, US and other intelligence reports had suggested that Iraq was operating a BW program. Coalition troops trained with protective gear and stockpiled the antibiotic
Antibiotic
An antibacterial is a compound or substance that kills or slows down the growth of bacteria.The term is often used synonymously with the term antibiotic; today, however, with increased knowledge of the causative agents of various infectious diseases, antibiotic has come to denote a broader range of...

 ciprofloxacin
Ciprofloxacin
Ciprofloxacin is a synthetic chemotherapeutic antibiotic of the fluoroquinolone drug class.It is a second-generation fluoroquinolone antibacterial. It kills bacteria by interfering with the enzymes that cause DNA to rewind after being copied, which stops synthesis of DNA and of...

 for use as post-exposure prophylaxis
Post-exposure prophylaxis
Post-exposure prophylaxis is any prophylactic treatment started immediately after exposure to a pathogen , in order to prevent infection by the pathogen and the development of disease.-Rabies:...

 against anthrax
Anthrax
Anthrax is an acute disease caused by the bacterium Bacillus anthracis. Most forms of the disease are lethal, and it affects both humans and other animals...

. Approximately 150,000 US troops received the U.S. Food and Drug Administration–licensed anthrax vaccine
Anthrax vaccine
Anthrax vaccines are vaccines against the infectious disease anthrax. Anthrax is caused by the spore-forming bacterium Bacillus anthracis, that most commonly occurs in wild and domestic mammals. Anthrax also occurs in humans when they are exposed to infected animals, hides, or tissue from infected...

 (BioThrax), and 8,000 received a botulinum toxoid vaccine also approved by the FDA as an investigational new drug
Investigational New Drug
The United States Food and Drug Administration's Investigational New Drug program is the means by which a pharmaceutical company obtains permission to ship an experimental drug across state lines before a marketing application for the drug has been approved...

.

Post-war inspections

In August 1991, the UN carried out its first inspection of Iraq’s BW capabilities in the aftermath of the Gulf War. On 2 August 1991, representatives of the Iraqi government announced to leaders of UNSCOM's "Team 7" that they had conducted research into the offensive use of B. anthracis, botulinum toxins, and Clostridium perfringens toxins. Post-war inspections by UNSCOM, however, were confounded by misinformation and obfuscation. After Iraqi General Hussein Kamel al-Majid defected to Jordon in August 1995, the Iraqi government further disclosed that it had operated a robust BW program at six major sites since the 1980s. It was revealed that the Iraqi program conducted basic research on B. anthracis, rotavirus
Rotavirus
Rotavirus is the most common cause of severe diarrhoea among infants and young children, and is one of several viruses that cause infections often called stomach flu, despite having no relation to influenza. It is a genus of double-stranded RNA virus in the family Reoviridae. By the age of five,...

, camelpox virus, aflatoxin
Aflatoxin
Aflatoxins are naturally occurring mycotoxins that are produced by many species of Aspergillus, a fungus, the most notable ones being Aspergillus flavus and Aspergillus parasiticus. Aflatoxins are toxic and among the most carcinogenic substances known...

, botulinum toxin
Botulinum toxin
Botulinum toxin is a protein produced by the bacterium Clostridium botulinum, and is considered the most powerful neurotoxin ever discovered. Botulinum toxin causes Botulism poisoning, a serious and life-threatening illness in humans and animals...

s, mycotoxin
Mycotoxin
A mycotoxin is a toxic secondary metabolite produced by organisms of the fungus kingdom, commonly known as molds. The term ‘mycotoxin’ is usually reserved for the toxic chemical products produced by fungi that readily colonize crops...

s, and an anticrop agent
Herbicidal warfare
Herbicidal warfare is a form of Chemical warfare in which the objective is to destroy the plant-based ecosystem of an area. In contrast to other forms, its use is not prohibited by international agreement...

 (wheat cover smut
Common bunt
Common bunt, also known as stinking smut and covered smut is a disease of both spring and winter wheats. It is caused by two very closely related fungi, Tilletia tritici and T. laevis Common bunt, also known as stinking smut and covered smut is a disease of both spring and winter wheats. It is...

). It tested several delivery systems including aerial spray tanks and drone aircraft. The Iraqi government had weaponized 6,000 liters of B. anthracis spores and 12,000 liters of botulinum toxin in aerial bombs, rockets, and missile warheads before the outbreak of war in 1991. These bio-weapons were deployed but never used.

Non-use by Hussein

After Kamel's defection, it became known that in December 1990 the Iraqis had filled 100 R-400 bombs with botulinum toxin, 50 with anthrax, and 16 with aflatoxin. In addition, 13 Al Hussein (SCUD)
Scud
Scud is a series of tactical ballistic missiles developed by the Soviet Union during the Cold War, and exported widely to other countries. The term comes from the NATO reporting name SS-1 Scud which was attached to the missile by Western intelligence agencies...

 warheads were filled with botulinum toxin, 10 with anthrax, and 2 with aflatoxin. These weapons were deployed in January 1991 to four locations for use against Coalition forces.

Why Saddam Hussein did not to use these biological weapons in 1991 is unclear, but the presumption has been that he was concerned about provoking massive retaliation. Other plausible factors include the perceived ineffectiveness of the untested delivery and dispersal systems, the probable ineffectiveness of liquid slurries resulting from poor aerosolization, and the potential hazards to the Iraqi troops themselves, as they lacked the protective equipment and training available to Coalition forces.

Several defectors (see Khidir Hamza
Khidir Hamza
Khidir Hamza is an Iraqi scientist who worked for Saddam Hussein's nuclear programme in the 1980s and early 1990s. Following the Gulf War, he left Iraq in 1994 and went into exile in the United States. He provided testimony to Western intelligence agencies suggesting that Hussein's weapons of mass...

) have claimed that these weapons were intended only as "weapons of last resort" in case the Coalition stormed the gates of Baghdad
Baghdad
Baghdad is the capital of Iraq, as well as the coterminous Baghdad Governorate. The population of Baghdad in 2011 is approximately 7,216,040...

. Since this never happened, Saddam found their use unnecessary.

2003 invasion of Iraq

The Iraqis claimed to have destroyed their biological arsenal immediately after the 1991 war, but they did not provide confirmatory evidence. A covert military research and development program continued for another four years, with the intent of resuming agent production and weapons manufacture after the end of UN sanctions. Basic infrastructure was preserved, and research on producing dried agent was conducted under the guise of biopesticide
Biopesticide
Biopesticides include "naturally occurring substances that control pests , microorganisms that control pests , and pesticidal substances produced by plants containing added genetic material or PIPs."Biopesticides are biochemical pesticides that are naturally occurring substances that control pests...

 production at Al Hakum until its destruction by UNSCOM inspectors in 1996. The same year, operational portions of the facilities at Salman Pak and Al Manal were also supposedly destroyed, either by the Iraqis themselves or under direct UNSCOM supervision. But UNSCOM inspectors never received full cooperation from the Hussein regime and they were finally expelled from Iraq in 1998. International concerns led to renewed inspections in 2002 under UN Security Council Resolution 1441 and these facilities were again targets for the U.S. military during the 2003 invasion of Iraq
2003 invasion of Iraq
The 2003 invasion of Iraq , was the start of the conflict known as the Iraq War, or Operation Iraqi Freedom, in which a combined force of troops from the United States, the United Kingdom, Australia and Poland invaded Iraq and toppled the regime of Saddam Hussein in 21 days of major combat operations...

 as potentially still being operational. President Bush
George W. Bush
George Walker Bush is an American politician who served as the 43rd President of the United States, from 2001 to 2009. Before that, he was the 46th Governor of Texas, having served from 1995 to 2000....

 cited the non-cooperation with inspectors as a major justification for military action
Rationale for the Iraq War
The rationale for the Iraq War has been a contentious issue since the Bush administration began actively pressing for military intervention in Iraq in late 2001. The primary rationalization for the Iraq War was articulated by a joint resolution of the U.S. Congress known as the Iraq Resolution.The...

.

The extent of Iraq’s BW program between 1998 when UNSCOM left Iraq and the U.S. Coalition invasion in March 2003 remains unknown. Current information indicates the discovery of a clandestine network of biological laboratories operated by the Iraqi Intelligence Service
Iraqi Intelligence Service
The Iraqi Intelligence Service , also known as the Mukhabarat, General Directorate of Intelligence, or Party Intelligence, was the main state intelligence organization in Iraq under Saddam Hussein...

 (Mukhabarat), a prison laboratory complex possibly used for human experimentation, an Iraqi scientist’s private culture collection with a strain of possible BW interest, and new research activities involving Brucella
Brucella
Brucella is a genus of Gram-negative bacteria. They are small , non-motile, non-encapsulated coccobacilli, which function as facultative intracellular parasites....

and Crimean-Congo hemorrhagic fever
Crimean-Congo hemorrhagic fever
Crimean–Congo hemorrhagic fever is a widespread tick-borne viral disease, a zoonosis of domestic animals and wild animals, that may affect humans. The pathogenic virus, especially common in East and West Africa, is a member of the Bunyaviridae family of RNA viruses. Clinical disease is rare in...

 virus. Despite diligent investigations since 2003, evidence for the existence of additional BW stockpiles in Iraq has not been documented.

2005 Iraq Survey Group report

In 2005, the Iraq Survey Group
Iraq Survey Group
The Iraq Survey Group was a fact-finding mission sent by the multinational force in Iraq after the 2003 invasion of Iraq to find the alleged weapons of mass destruction alleged to be possessed by Iraq that had been the main ostensible reason for the invasion. Its final report is commonly called...

 — an international group composed of civilian and military experts — concluded that the Iraqi military BW program had been abandoned during 1995 and 1996 because of fear that discovery of continued activity would result in severe political repercussions including the extension of UN sanctions. However, they concluded, Hussein had perpetuated ambiguity regarding a possible program as a strategic deterrent against Iran
Iran
Iran , officially the Islamic Republic of Iran , is a country in Southern and Western Asia. The name "Iran" has been in use natively since the Sassanian era and came into use internationally in 1935, before which the country was known to the Western world as Persia...

. Other conclusions were that the Mukhabarat continued to investigate toxins as tools of assassination, concealed its program from UNSCOM inspectors after the 1991 war, and reportedly conducted lethal human experimentation until 1994. Small-scale covert laboratories were maintained until 2003.

See also

  • Iraq and weapons of mass destruction
    Iraq and weapons of mass destruction
    During the regime of Saddam Hussein, the nation of Iraq used, possessed, and made efforts to acquire weapons of mass destruction . Hussein was internationally known for his use of chemical weapons in the 1980s against Iranian and Kurdish civilians during and after the Iran–Iraq War...

  • Rihab Taha
    Rihab Taha
    Rihab Rashid Taha al-Azawi is an Iraqi microbiologist, dubbed Dr. Germ by United Nations weapons inspectors, who worked in Saddam Hussein's biological weapons program. A 1999 report commissioned by the United States Joint Chiefs of Staff and the Defense Intelligence Agency named her as one of the...

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