| County | Location | Mile | # | Destinations | Notes |
|---|
| Lorain | North Ridgeville | 0.00 | | | Westbound exit and eastbound entrance |
| ~0.9 | Ohio Turnpike toll plaza; pay toll eastbound, get ticket westbound |
|---|
| 1.16 | 1 | | Westbound exit and eastbound entrance; SR 10 joins eastbound and leaves westbound |
| 2.03 | 2 | | SR 10 leaves eastbound and joins westbound |
| Cuyahoga | North Olmsted | 3.67 | 3 | Stearns Road | |
| 6.15 | 6A-B | | |
| 7.57 | 7 | Clague Road – Westlake, Fairview Park | Westbound exit and eastbound entrance |
| Cleveland | 9.44 | 9 | | |
| 10.17 | 11 | | Eastbound exit and westbound entrance |
| 10.17 | 10 | | Westbound exit and eastbound entrance |
| 10.71 | 11 | | Westbound exit and eastbound entrance |
| 11.60 | 12A | West 150th Street – Brook Park | Westbound exit and eastbound entrance |
| 12.71 | 12B | West 130th Street/West 150th Street – Brook Park | Signed as exit 12 eastbound |
| Brooklyn | 13.79 | 13 | Tiedeman Road – Brooklyn | |
| 15.21 | 15 | via Ridge Road | |
| Brooklyn Heights | 16.49 | 16 | | |
| 17.76 | 17A | | Signed as exit 17 eastbound |
| 18.03 | 17B | | Westbound exit and eastbound entrance |
| Independence | 20.05 | 20A-B | | Also provides access to Rockside Road |
| Garfield Heights | 21.72 | 21 | Transportation Boulevard/East 98th Street |
| 22.92 | 22 | | Eastbound exit and westbound entrance |
| 23.85 | 23 | | Was to be south end of Bedford Freeway |
| Cleveland | 24.58 | 24 | Lee Road – Maple Heights | Westbound exit and eastbound entrance |
| Warrensville Heights | 26.03 | 25A-B | Warrensville Road | Eastbound exit and westbound entrance |
| 26.31 | 26 | Erie, Warren | Eastbound exit and westbound entrance; unsigned I-480N |
| Bedford Heights | 26.55 | 25C | | |
| 27.94 | 26A | Rockside Road | Westbound exit and eastbound entrance |
| 28.02 | | Erie | Westbound exit and eastbound entrance; I-271 joins eastbound and leaves westbound |
| Begin I-271 exit numbering eastbound; resume I-480 exit numbering westbound |
|---|
| Oakwood | 30.99 | 23 | | SR 14 joins eastbound and leaves westbound |
| 32.06 | | | Eastbound exit and westbound entrance; I-271 joins westbound and leaves eastbound |
| Resume I-480 exit numbering eastbound; begin I-271 exit numbering westbound |
|---|
| Summit | Twinsburg | 36.30 | 36 | | |
| 36.99 | 37 | | |
| Portage | Streetsboro | 41.63 | 41 | Frost Road |
| 42.45 | 42 | | |
| | | Continuation of I-480 beyond I-80/Turnpike |