International Protein Index
Encyclopedia
The International Protein Index (IPI) is database that was created to give the proteomics
Proteomics
Proteomics is the large-scale study of proteins, particularly their structures and functions. Proteins are vital parts of living organisms, as they are the main components of the physiological metabolic pathways of cells. The term "proteomics" was first coined in 1997 to make an analogy with...

 community a resource that enables
  • accession numbers
    Accession number (bioinformatics)
    An accession number in bioinformatics is a unique identifier given to a DNA or protein sequence record to allow for tracking of different versions of that sequence record and the associated sequence over time in a single data repository...

     from a variety of bioinformatics
    Bioinformatics
    Bioinformatics is the application of computer science and information technology to the field of biology and medicine. Bioinformatics deals with algorithms, databases and information systems, web technologies, artificial intelligence and soft computing, information and computation theory, software...

     databases to be mapped
  • a complete set of proteins for a species i.e. a reference set


IPI was launched in 2001 by the European Bioinformatics Institute
European Bioinformatics Institute
The European Bioinformatics Institute is a centre for research and services in bioinformatics, and is part of European Molecular Biology Laboratory...

 (EBI) when databases cataloguing human genes varied greatly and had few links between them. Since then much more data has been produced giving a more complete picture and databases have collaborated to synchronize data. Currently many model organisms have a reference set of genes/proteins which are catalogued in Ensembl
Ensembl
Ensembl is a joint scientific project between the European Bioinformatics Institute and the Wellcome Trust Sanger Institute, which was launched in 1999 in response to the imminent completion of the Human Genome Project...

/UniProt
UniProt
UniProt is a comprehensive, high-quality and freely accessible database of protein sequence and functional information, many of which are derived from genome sequencing projects...

respectively, as well as other species specific databases.

Retirement

Due to advances in data organization the need for IPI is diminishing. The EBI has announced that this service will be closing when appropriate and has advised users of its services to employ UniProtKB accession numbers as their protein identifiers.

External links

The source of this article is wikipedia, the free encyclopedia.  The text of this article is licensed under the GFDL.
 
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