International Classification of Diseases for Oncology
Encyclopedia
The International Classification of Diseases for Oncology (ICD-O) is a domain specific extension of the International Statistical Classification of Diseases and Related Health Problems
ICD
The International Statistical Classification of Diseases and Related Health Problems is a medical classification that provides codes to classify diseases and a wide variety of signs, symptoms, abnormal findings, complaints, social circumstances, and external causes of injury or disease...

 for tumor
Tumor
A tumor or tumour is commonly used as a synonym for a neoplasm that appears enlarged in size. Tumor is not synonymous with cancer...

 diseases. This classification is widely used by cancer registries
Cancer registry
A cancer registry is a systematic collection of data about cancer and tumor diseases. The data is collected by Cancer Registrars. Cancer Registrars capture a complete summary of patient history, diagnosis, treatment, and status for every cancer patient in the United States, and other countries as...

.

It is currently in its third revision (ICD-O-3). ICD-10 includes a list of morphology codes. They stem from ICD-O second edition (ICD-O-2) that was valid at the time of publication.

Morphology

The morphology axis is for the morphology
Morphology (biology)
In biology, morphology is a branch of bioscience dealing with the study of the form and structure of organisms and their specific structural features....

 of the tumor.

This axis has additional importance, because the Systematized Nomenclature of Medicine
Systematized Nomenclature of Medicine
The Systematized Nomenclature of Medicine is a multiaxial, hierarchical classification system . As in any such system, a disease may be located in a body organ which results in a code in a topography axis and may lead to morphological alterations represented by a morphology code.-Purpose:SNOMED...

(SNOMED) has adopted ICD-O's classification of morphology. SNOMED has been changing continuously, and several different versions of SNOMED are in use. Accordingly, mapping of ICD-O codes to SNOMED requires careful assessment whether entities really match, or not.
(8000–8009) Not otherwise specified
  • (8000–8004) Neoplasms, NOS
    • Neoplasm, benign
      Benign
      A benign tumor is a tumor that lacks the ability to metastasize. Common examples of benign tumors include moles and uterine fibroids.The term "benign" implies a mild and nonprogressive disease. Indeed, many kinds of benign tumors are harmless to human health...

    • Neoplasm, uncertain whether benign
      Benign
      A benign tumor is a tumor that lacks the ability to metastasize. Common examples of benign tumors include moles and uterine fibroids.The term "benign" implies a mild and nonprogressive disease. Indeed, many kinds of benign tumors are harmless to human health...

       or malignant
      Malignant
      Malignancy is the tendency of a medical condition, especially tumors, to become progressively worse and to potentially result in death. Malignancy in cancers is characterized by anaplasia, invasiveness, and metastasis...

    • Neoplasm, malignant
      Malignant
      Malignancy is the tendency of a medical condition, especially tumors, to become progressively worse and to potentially result in death. Malignancy in cancers is characterized by anaplasia, invasiveness, and metastasis...

    • Neoplasm, metastatic
    • Neoplasm, malignant
      Malignant
      Malignancy is the tendency of a medical condition, especially tumors, to become progressively worse and to potentially result in death. Malignancy in cancers is characterized by anaplasia, invasiveness, and metastasis...

      , uncertain whether primary or metastatic

(8010–8790) Epithelial 
  • (8010–8040) Epithelial neoplasms, NOS
  • (8050–8080) Squamous cell neoplasms
    • Squamous cell carcinoma
      Squamous cell carcinoma
      Squamous cell carcinoma , occasionally rendered as "squamous-cell carcinoma", is a histologically distinct form of cancer. It arises from the uncontrolled multiplication of malignant cells deriving from epithelium, or showing particular cytological or tissue architectural characteristics of...

      , NOS
  • (8090–8110) Basal cell neoplasms
    • Basal cell carcinoma
      Basal cell carcinoma
      Basal-cell carcinoma is the most common type of skin cancer. It rarely metastasizes or kills. However, because it can cause significant destruction and disfigurement by invading surrounding tissues, it is still considered malignant. Statistically, approximately 3 out of 10 Caucasians may develop a...

      , NOS
  • (8120–8130) Transitional cell Papillomas And Carcinomas
  • (8140–8380) Adenomas And Adenocarcinomas (gland
    Gland
    A gland is an organ in an animal's body that synthesizes a substance for release of substances such as hormones or breast milk, often into the bloodstream or into cavities inside the body or its outer surface .- Types :...

    s)
    • Adenoma
      Adenoma
      An adenoma is a benign tumor of glandular origin. Adenomas can grow from many organs including the colon, adrenal glands, pituitary gland, thyroid, prostate, etc. Although these growths are benign, over time they may progress to become malignant, at which point they are called adenocarcinomas...

      , NOS
    • Adenocarcinoma
      Adenocarcinoma
      Adenocarcinoma is a cancer of an epithelium that originates in glandular tissue. Epithelial tissue includes, but is not limited to, the surface layer of skin, glands and a variety of other tissue that lines the cavities and organs of the body. Epithelium can be derived embryologically from...

      , NOS
    • Linitis plastica
      Linitis plastica
      Linitis plastica, also known as Brinton's disease or leather bottle stomach, is a morphological variant of diffuse stomach cancer....

    • Insulinoma
      Insulinoma
      An insulinoma is a tumour of the pancreas that is derived from beta cells and secretes insulin.Beta cells secrete insulin in response to increases in blood glucose. The resulting increase in insulin acts to lower blood glucose back to normal levels at which point further secretion of insulin is...

      , NOS
    • Glucagonoma
      Glucagonoma
      A glucagonoma is a rare tumor of the alpha cells of the pancreas that results in up to a 1000-fold overproduction of the hormone glucagon. Alpha cell tumors are commonly associated with glucagonoma syndrome, though similar symptoms are present in cases of pseudoglucagonoma syndrome in the absence...

      , NOS
    • Gastrinoma
      Gastrinoma
      A gastrinoma is a tumor in the pancreas or duodenum that secretes excess of gastrin leading to ulceration in the duodenum, stomach and the small intestine. There is hypersecretion of the HCl in the duodenum which causes the ulcers...

      , NOS
    • Vipoma
      VIPoma
      A VIPoma is a rare endocrine tumor, usually originating in the pancreas, that produces vasoactive intestinal peptide ....

    • Cholangiocarcinoma
      Cholangiocarcinoma
      Cholangiocarcinoma is a cancer of the bile ducts which drain bile from the liver into the small intestine. Other biliary tract cancers include pancreatic cancer, gallbladder cancer, and cancer of the ampulla of Vater...

    • Hepatocellular carcinoma
      Hepatocellular carcinoma
      Hepatocellular carcinoma is the most common type of liver cancer. Most cases of HCC are secondary to either a viral hepatitide infection or cirrhosis .Compared to other cancers, HCC is quite a rare tumor in the United States...

      , NOS
    • Adenoid cystic carcinoma
      Adenoid cystic carcinoma
      Adenoid cystic cancer is a rare type of cancer that can exist in many different body sites. It most often occurs in the areas of the head and neck, in particular the salivary glands; but has also been reported in the breast, lacrimal gland of the eye, lung, brain, bartholin gland, trachea, and...

    • Carcinoid
      Carcinoid
      Carcinoid is a slow-growing type of neuroendocrine tumor, originating in the cells of the neuroendocrine system.In 2000, the World Health Organization redefined "carcinoid", but this new definition has not been accepted by all practitioners. This has led to some complexity in distinguishing...

       tumor, NOS, of appendix
      Vermiform appendix
      The appendix is a blind-ended tube connected to the cecum , from which it develops embryologically. The cecum is a pouchlike structure of the colon...

    • Prolactinoma
      Prolactinoma
      A prolactinoma is a benign tumor of the pituitary gland that produces a hormone called prolactin. It is the most common type of pituitary tumor...

    • Oncocytoma
      Oncocytoma
      An oncocytoma is a tumor made up of oncocytes, a special kind of cells. -Presentation:An oncocytoma is an epithelial tumor composed of oncocytes, large eosinophilic cells having small, round, benign-appearing nuclei with large nucleoli....

    • Hurthle cell adenoma
    • Renal cell carcinoma
      Renal cell carcinoma
      Renal cell carcinoma is a kidney cancer that originates in the lining of the proximal convoluted tubule, the very small tubes in the kidney that filter the blood and remove waste products. RCC is the most common type of kidney cancer in adults, responsible for approximately 80% of cases...

    • Grawitz tumor
    • Multiple endocrine adenomas
    • Endometrioid adenoma, NOS
  • (8390–8420) Adnexal And Skin appendage
    Skin appendage
    Skin appendages are appendages that are associated with the skin and serve a particular function. In humans some of the more common skin appendages are hairs , arrector pilli , sebaceous glands , sweat glands Skin appendages are appendages that are associated with the skin and serve a particular...

     Neoplasms
  • (8430–8439) Mucoepidermoid Neoplasms
  • (8440–8490) Cystic, Mucinous And Serous Neoplasms
    • Cystadenoma
      Cystadenoma
      Cystadenoma refers to a type of cystic adenoma.When malignant, it is called cystadenocarcinoma.-Classification:When not otherwise specified, the ICD-O coding is 8440/0...

      , NOS
    • Pseudomyxoma peritonei
      Pseudomyxoma peritonei
      Pseudomyxoma Peritonei is an uncommon tumor known for its production of mucin in the abdominal cavity. If left untreated, mucin will eventually build up to the point where it compresses vital structures: the colon, the liver, kidneys,stomach, spleen, pancreas, etc.Unlike most cancers, this disease...

  • (8500–8540) Ductal, Lobular And Medullary Neoplasms
  • (8550–8559) Acinar cell
    Acinar cell
    Acinar cell may refer to:* Centroacinar cells of the pancreas* Other acinus cells...

     neoplasms
  • (8560–8580) Complex epithelial neoplasms
    • Warthin's tumor
      Warthin's tumor
      Warthin's tumor or Warthin tumour, also known as papillary cystadenoma lymphomatosum or adenolymphoma, is a type of benign tumor of the salivary glands.-Etiology:Its etiology is unknown, but there is a strong association with cigarette smoking...

    • Thymoma
      Thymoma
      Thymoma is a tumor originating from the epithelial cells of the thymus. Thymoma is an uncommon tumor, best known for its association with the neuromuscular disorder myasthenia gravis. Thymoma is found in 15% of patients with myasthenia gravis. Once diagnosed, thymomas may be removed surgically...

      , NOS
  • (8590–8670) Specialized gonadal neoplasms
    • Sex cord-stromal tumor
    • Thecoma
      Thecoma
      Thecomas or theca cell tumors are benign ovarian neoplasms composed only of theca cells. Histogenetically they are classified as sex cord-stromal tumours....

      , NOS
    • Granulosa cell tumor, NOS
    • Arrhenoblastoma, NOS
    • Sertoli-Leydig cell tumor
  • (8680–8710) Paragangliomas And Glomus tumor
    Glomus tumor
    A glomus tumor is a rare benign neoplasm arising from the glomus body...

    s
    • Paraganglioma
      Paraganglioma
      A paraganglioma is a rare neuroendocrine neoplasm that may develop at various body sites . About 97% are benign and cured by surgical removal; the remaining 3% are malignant because they are able to produce distant metastases...

      , NOS
    • Pheochromocytoma
      Pheochromocytoma
      A pheochromocytoma or phaeochromocytoma is a neuroendocrine tumor of the medulla of the adrenal glands , or extra-adrenal chromaffin tissue that failed to involute after birth and secretes excessive amounts of catecholamines, usually noradrenaline , and adrenaline to a lesser extent...

      , NOS
    • Glomus tumor
      Glomus tumor
      A glomus tumor is a rare benign neoplasm arising from the glomus body...

  • (8720–8790) Nevi And Melanomas
    • Melanocytic nevus
      Melanocytic nevus
      A melanocytic nevus is a type of lesion that contains nevus cells .Some sources equate the term mole with "melanocytic nevus". Other sources reserve the term "mole" for other purposes....

    • Malignant melanoma, NOS
    • Melanoma
      Melanoma
      Melanoma is a malignant tumor of melanocytes. Melanocytes are cells that produce the dark pigment, melanin, which is responsible for the color of skin. They predominantly occur in skin, but are also found in other parts of the body, including the bowel and the eye...

      , NOS
    • Nodular melanoma
      Nodular melanoma
      Nodular melanoma is the most aggressive form of melanoma. It tends to grow more rapidly in thickness than in diameter. Instead of arising from a pre-existing mole, it may appear in a spot where a lesion did not previously exist...

    • Dysplastic nevus
      Dysplastic nevus
      A dysplastic nevus is an atypical melanocytic nevus; a mole whose appearance is different from that of common moles. Dysplastic nevi are generally larger than ordinary moles and have irregular and indistinct borders...

    • Lentigo maligna melanoma
      Lentigo maligna melanoma
      Lentigo maligna melanoma is a melanoma that has evolved from a lentigo maligna. They are usually found on chronically sun damaged skin such as the face and the forearms of the elderly. The nomenclature is very confusing to both patients and physicians alike....

    • Superficial spreading melanoma
      Superficial spreading melanoma
      Superficial spreading melanoma is usually characterized as the most common form of cutaneous melanoma in Caucasians...

    • Acral lentiginous melanoma
      Acral lentiginous melanoma
      Acral lentiginous melanoma is a kind of lentiginous skin cancer skin melanoma.Acral lentiginous melanoma is observed on the palms, soles, under the nails and in the oral mucosa. It occurs on non hair-bearing surfaces of the body which may or may not be exposed to sunlight. It is also found on...

      , malignant
    • Melanoma, desmoplastic, amelanotic

(8800–9370) Connective tissue
Connective tissue
"Connective tissue" is a fibrous tissue. It is one of the four traditional classes of tissues . Connective Tissue is found throughout the body.In fact the whole framework of the skeleton and the different specialized connective tissues from the crown of the head to the toes determine the form of...

  • (8800–8809) Soft tissue
    Soft tissue
    In anatomy, the term soft tissue refers to tissues that connect, support, or surround other structures and organs of the body, not being bone. Soft tissue includes tendons, ligaments, fascia, skin, fibrous tissues, fat, and synovial membranes , and muscles, nerves and blood vessels .It is sometimes...

     Tumors And Sarcomas, Nos
    • Sarcoma
      Sarcoma
      A sarcoma is a cancer that arises from transformed cells in one of a number of tissues that develop from embryonic mesoderm. Thus, sarcomas include tumors of bone, cartilage, fat, muscle, vascular, and hematopoietic tissues...

      , NOS
    • Soft tissue sarcoma
      Soft tissue sarcoma
      A soft-tissue sarcoma is a form of sarcoma that develops in connective tissue, though the term is sometimes applied to elements of the soft tissue that are not currently considered connective tissue.-Risk factors:...

    • Desmoplastic small round cell tumor
      Desmoplastic small round cell tumor
      Desmoplastic small-round-cell tumor is classified as a soft tissue sarcoma. It is an aggressive and rare tumor that primarily occurs as masses in the abdomen. Other areas affected may include the lymph nodes, the lining of the abdomen, diaphragm, spleen, liver, chest wall, skull, spinal cord, large...

  • (8810–8830) Fibromatous neoplasms
    • Fibroma
      Fibroma
      Fibromas are benign tumors that are composed of fibrous or connective tissue. They can grow in all organs, arising from mesenchyme tissue. The term "fibroblastic" or "fibromatous" is used to describe tumors of the fibrous connective tissue...

      , NOS
    • Fibrosarcoma
      Fibrosarcoma
      Fibrosarcoma is a malignant tumor derived from fibrous connective tissue and characterized by immature proliferating fibroblasts or undifferentiated anaplastic spindle cells.Usually in males ages 30 to 40. Originates in fibrous tissues of the bone. Invades long or flat bones such as femur, tibia,...

      , NOS
  • (8840–8849) Myxomatous neoplasms
    • Myxoma
      Myxoma
      A myxoma is a tumor of primitive connective tissue. It is the most common primary tumor of the heart in adults, but can also occur in other locations....

      , NOS
  • (8850–8880) Lipomatous neoplasms
    • Lipoma
      Lipoma
      A lipoma is a benign tumor composed of adipose tissue. It is the most common form of soft tissue tumor. Lipomas are soft to the touch, usually movable, and are generally painless. Many lipomas are small but can enlarge to sizes greater than six centimeters. Lipomas are commonly found in adults...

      , NOS
    • Liposarcoma
      Liposarcoma
      Liposarcoma is a malignant tumor that arises in fat cells in deep soft tissue, such as that inside the thigh or in the retroperitoneum.They are typically large bulky tumors which tend to have multiple smaller satellites extending beyond the main confines of the tumor.Liposarcomas, like all...

      , NOS
  • (8890–8920) Myomatous neoplasms
    • Leiomyoma
      Leiomyoma
      A leiomyoma is a benign smooth muscle neoplasm that is not premalignant. They can occur in any organ, but the most common forms occur in the uterus, small bowel and the esophagus.- Etymology:* Greek:** λεῖος leios "smooth"...

      , NOS
    • Leiomyosarcoma
      Leiomyosarcoma
      Leiomyosarcoma , aka LMS, is a malignant cancer of smooth muscle....

      , NOS
    • Myoma
      Myoma
      Myoma is a kind of mesenchymal tumor.-Classification:They are of two types.* The leiomyoma occurs in the skin or gut but the common form is the uterine fibroid.* Rhabdomyomas are rare tumors of muscles, they occur in childhood and often become malignant....

    • Myosarcoma
      Myosarcoma
      Myosarcoma is a malignant muscle tumor.Leiomyosarcoma refers to sarcoma of smooth muscle, and rhabdomyosarcoma refers to sarcoma of striated muscle. However, the term myosarcoma itself still appears in the literature....

    • Rhabdomyoma
      Rhabdomyoma
      A rhabdomyoma is a benign tumor of striated muscle. Rhabdomyomas may be either "cardiac" or "extracardiac" . Extracardiac forms of rhabdomyoma are subclassified into three distinct types: Adult type, Fetal type, and Genital type.Cardiac rhabdomyomas are the most common primary tumor of the heart...

      , NOS
    • Rhabdomyosarcoma
      Rhabdomyosarcoma
      A rhabdomyosarcoma is a type of cancer, specifically a sarcoma , in which the cancer cells are thought to arise from skeletal muscle progenitors. It can also be found attached to muscle tissue, wrapped around intestines, or in any anatomic location...

      , NOS
  • (8930–8990) Complex Mixed And Stromal Neoplasms
    • Pleomorphic adenoma
      Pleomorphic adenoma
      Pleomorphic adenoma is a common benign salivary gland neoplasm characterised by neoplastic proliferation of parenchymatous glandular cells along with myoepithelial components, having a malignant potentiality. It is the most common type of salivary gland tumor and the most common tumor of the...

    • Nephroblastoma, NOS (Wilms's tumor)
  • (9000–9030) Fibroepithelial Neoplasms
    • Brenner tumor, NOS
  • (9040–9049) Synovial
    Synovial
    Synovial may refer to:* Synovial fluid* Synovial joint* Synovial membrane...

    -Like Neoplasms
    • Synovial sarcoma
      Synovial sarcoma
      A synovial sarcoma is a rare form of cancer which usually occurs near to the joints of the arm, neck or leg. It is one of the soft tissue sarcomas....

      , NOS
  • (9050–9059) Mesothelial Neoplasms
    • Mesothelioma
      Mesothelioma
      Mesothelioma, more precisely malignant mesothelioma, is a rare form of cancer that develops from the protective lining that covers many of the body's internal organs, the mesothelium...

      , benign
    • Mesothelioma
      Mesothelioma
      Mesothelioma, more precisely malignant mesothelioma, is a rare form of cancer that develops from the protective lining that covers many of the body's internal organs, the mesothelium...

      , NOS
  • (9060–9090) Germ cell Neoplasms
    • Dysgerminoma
      Dysgerminoma
      A dysgerminoma is a type of germ cell tumor; it usually is malignant and usually occurs in the ovary.A tumor of the identical histology but not occurring in the ovary may be described by an alternate name: seminoma in the testis or germinoma in the central nervous system or other parts of the...

    • Germ cell tumor
      Germ cell tumor
      A germ cell tumor is a neoplasm derived from germ cells. Germ cell tumors can be cancerous or non-cancerous tumors. Germ cells normally occur inside the gonads...

      , NOS
    • Embryonal carcinoma
      Embryonal carcinoma
      Embryonal carcinoma is a relatively uncommon type of germ cell tumour that occurs in the ovaries and testes.-Ovarian embryonal carcinoma:In the ovary, embryonal carcinoma is quite rare, amounting to approximately three percent of ovarian germ cell tumours. The median age at diagnosis is 15 years...

      , NOS
    • Yolk sac tumor
    • Teratoma
      Teratoma
      A teratoma is an encapsulated tumor with tissue or organ components resembling normal derivatives of all three germ layers. There are rare occasions when not all three germ layers are identifiable...

      , benign
    • Teratoma
      Teratoma
      A teratoma is an encapsulated tumor with tissue or organ components resembling normal derivatives of all three germ layers. There are rare occasions when not all three germ layers are identifiable...

      , malignant, NOS
    • Dermoid cyst
      Dermoid cyst
      A dermoid cyst is a cystic teratoma that contains developmentally mature skin complete with hair follicles and sweat glands, sometimes clumps of long hair, and often pockets of sebum, blood, fat, bone, nails, teeth, eyes, cartilage, and thyroid tissue. Because it contains mature tissue, a dermoid...

      , NOS
  • (9100–9109) Trophoblastic neoplasms
    • Choriocarcinoma
      Choriocarcinoma
      Choriocarcinoma is a malignant, trophoblastic and aggressive cancer, usually of the placenta. It is characterized by early hematogenous spread to the lungs...

      , NOS
  • (9110–9119) Mesonephromas
  • (9120–9160) Blood vessel
    Blood vessel
    The blood vessels are the part of the circulatory system that transports blood throughout the body. There are three major types of blood vessels: the arteries, which carry the blood away from the heart; the capillaries, which enable the actual exchange of water and chemicals between the blood and...

     tumors
    • Hemangioma
      Hemangioma
      A hemangioma of infancy is a benign self-involuting tumor of endothelial cells, the cells that line blood vessels. It usually appears during the first weeks of life and sometimes resolves by age 10. In more severe case hemangioma may have permanency, if not treated by a physician...

      , NOS
    • Angioma
      Angioma
      Angiomas are benign tumors derived from cells of the vascular or lymphatic vessel walls or derived from cells of the tissues surrounding these vessels....

      , NOS
    • Hemangiosarcoma
      Hemangiosarcoma
      Hemangiosarcoma is a rare, rapidly growing, highly invasive variety of cancer. It is a sarcoma arising from the lining of blood vessels; that is, blood-filled channels and spaces are commonly observed microscopically...

    • Angiosarcoma
      Angiosarcoma
      Angiosarcoma is a malignant neoplasm of endothelial-type cells that line vessel walls. This may be in reference to blood or lymphatic vessels ....

    • Hemangioendothelioma
      Hemangioendothelioma
      Hemangioendothelioma is used to describe a group of vascular neoplasms that may be considered benign or malignant in their activity.-Presentation:They have been described as masses that fall between a hemangioma and angiosarcoma...

      , benign
    • Hemangioendothelioma
      Hemangioendothelioma
      Hemangioendothelioma is used to describe a group of vascular neoplasms that may be considered benign or malignant in their activity.-Presentation:They have been described as masses that fall between a hemangioma and angiosarcoma...

      , NOS
    • Kaposi's sarcoma
      Kaposi's sarcoma
      Kaposi's sarcoma is a tumor caused by Human herpesvirus 8 , also known as Kaposi's sarcoma-associated herpesvirus . It was originally described by Moritz Kaposi , a Hungarian dermatologist practicing at the University of Vienna in 1872. It became more widely known as one of the AIDS defining...

    • Hemangiopericytoma
      Hemangiopericytoma
      A hemangeopericytoma is a type of soft tissue sarcoma that originates in the pericytes in the walls of capillaries. When inside the nervous system, although not strictly a meningioma tumor, it is a meningeal tumor with an especially aggressive behavior.It was characterized in...

      , benign
    • Hemangiopericytoma
      Hemangiopericytoma
      A hemangeopericytoma is a type of soft tissue sarcoma that originates in the pericytes in the walls of capillaries. When inside the nervous system, although not strictly a meningioma tumor, it is a meningeal tumor with an especially aggressive behavior.It was characterized in...

      , NOS
  • (9170–9179) Lymphatic vessel tumors
    • Lymphangioma
      Lymphangioma
      Lymphangiomas are malformations of the lymphatic system, which is the network of vessels responsible for returning to the venous system excess fluid from tissues. These malformations can occur at any age and may involve any part of the body, but 90% occur in children less than 2 years of age and...

      , NOS
    • Cystic lymphangioma
  • (9180–9240) Osseous And Chondromatous neoplasms
    • Osteoma
      Osteoma
      An osteoma is a new piece of bone usually growing on another piece of bone, typically the skull. It is a benign tumor.When the bone tumor grows on other bone it is known as "homoplastic osteoma"; when it grows on other tissue it is called "heteroplastic osteoma".Osteoma represents the most common...

      , NOS
    • Osteosarcoma
      Osteosarcoma
      Osteosarcoma is an aggressive cancerous neoplasm arising from primitive transformed cells of mesenchymal origin that exhibit osteoblastic differentiation and produce malignant osteoid...

      , NOS
    • Osteochondroma
      Osteochondroma
      Osteochondroma is a type of benign tumor that consists of cartilage and bone. It is a benign capped-cartilage outgrowth, connected to bone by a stalk.It is the most frequently observed neoplasm of the skeleton....

    • Cartilaginous exostosis
      Exostosis
      An exostosis is the formation of new bone on the surface of a bone. Exostoses can cause chronic pain ranging from mild to debilitatingly severe, depending on where they are located and what shape they are....

    • Chondroma
      Chondroma
      A chondroma is a benign cartilaginous tumor, which is encapsulated with a lobular growing pattern.Tumor cells resemble normal cells and produce the cartilaginous matrix ....

      , NOS
    • Chondrosarcoma
      Chondrosarcoma
      Chondrosarcoma is a cancer composed of cells derived from transformed cells that produce cartilage. Chondrosarcoma is a member of a category of "soft tissue" malignancies known as sarcomas. About 30% of skeletal system cancers are chondrosarcomas...

      , NOS
  • (9250–9259) Giant cell
    Giant cell
    A giant cell is a mass formed by the union of several distinct cells . It can arise in response to an infection or foreign body.Types include:* foreign-body giant cell* Langhans giant cell* Touton giant cells...

     tumors
  • (9260–9269) Miscellaneous bone tumors
    • Ewing's sarcoma
  • (9270–9340) Odontogenic tumors
    • Cementoblastoma
      Cementoblastoma
      Cementoblastoma, or benign cementoblastoma, is a relatively uncommon benign neoplasm of the cementum of the teeth.-Clinical features:Cementoblastoma usually occurs in people under the age of 25, often involving the mandibular molars or premolars. The involved tooth usually has a vital pulp...

      , benign
    • Ameloblastoma
      Ameloblastoma
      Ameloblastoma is a rare, benign tumor of odontogenic epithelium much more commonly appearing in the lower jaw than the upper jaw. It was recognized in 1827 by Cusack...

      , NOS
  • (9350–9370) Miscellaneous tumors
    • Craniopharyngioma
      Craniopharyngioma
      Craniopharyngioma is a type of brain tumor derived from pituitary gland embryonic tissue, that occurs most commonly in children but also in men and women in their 50s and 60s....


(9380–9589) Nervous system
Nervous system
The nervous system is an organ system containing a network of specialized cells called neurons that coordinate the actions of an animal and transmit signals between different parts of its body. In most animals the nervous system consists of two parts, central and peripheral. The central nervous...

  • (9380–9480) Gliomas
    • Mixed oligoastrocytoma
      Oligoastrocytoma
      Oligoastrocytomas are a subset of brain tumors that present with an appearance of mixed glial cell origin, astrocytoma and oligodendroglioma. These types of glial cells that become cancerous are involved with insulating and regulating the activity of neuron cells in the central nervous system...

    • Ependymoma
      Ependymoma
      Ependymoma is a tumor that arises from the ependyma, a tissue of the central nervous system. Usually, in pediatric cases the location is intracranial, while in adults it is spinal. The common location of intracranial ependymoma is the fourth ventricle...

      , NOS
    • Astrocytoma
      Astrocytoma
      Astrocytomas are a type of neoplasm of the brain. They originate in a particular kind of glial-cells, star-shaped brain cells in the cerebrum called astrocytes. This type of tumor does not usually spread outside the brain and spinal cord and it does not usually affect other organs...

      , NOS
      • (9421/3) Pilocytic astrocytoma
        Pilocytic astrocytoma
        Pilocytic astrocytoma or juvenile pilocytic astrocytoma or cystic cerebellar astrocytoma is a neoplasm of the brain that occurs more often in children and young adults...

      • (9440/3) Glioblastoma multiforme
        Glioblastoma multiforme
        Glioblastoma multiforme is the most common and most aggressive malignant primary brain tumor in humans, involving glial cells and accounting for 52% of all functional tissue brain tumor cases and 20% of all intracranial tumors. Despite being the most prevalent form of primary brain tumor, GBMs...

    • Oligodendroglioma
      Oligodendroglioma
      Oligodendrogliomas are a type of glioma that are believed to originate from the oligodendrocytes of the brain or from a glial precursor cell. They occur primarily in adults but are also found in children...

      , NOS
  • (9490–9520) Neuroepitheliomatous neoplasms
    • Neuroblastoma
      Neuroblastoma
      Neuroblastoma is the most common extracranial solid cancer in childhood and the most common cancer in infancy, with an annual incidence of about 650 cases per year in the US , and 100 cases per year in the UK . Close to 50 percent of neuroblastoma cases occur in children younger than two years old...

      , NOS
    • Retinoblastoma
      Retinoblastoma
      Retinoblastoma is a rapidly developing cancer that develops in the cells of retina, the light-detecting tissue of the eye. In the developed world, Rb has one of the best cure rates of all childhood cancers , with more than nine out of every ten sufferers surviving into...

  • (9530–9539) Meningiomas
  • (9540–9570) Nerve sheath tumors
    • Neurofibroma
      Neurofibroma
      A neurofibroma is a benign nerve sheath tumor in the peripheral nervous system. Usually found in individuals with neurofibromatosis type I , an autosomal dominant genetically-inherited disease, they can result in a range of symptoms from physical disfiguration and pain to cognitive disability...

      , NOS
    • Neurofibromatosis
      Neurofibromatosis
      Neurofibromatosis is a genetically-inherited disorder in which the nerve tissue grows tumors that may be benign or may cause serious damage by compressing nerves and other tissues...

      , NOS
    • Schwannoma
      Schwannoma
      A schwannoma is a benign nerve sheath tumor composed of Schwann cells, which normally produce the insulating myelin sheath covering peripheral nerves....

      , NOS
    • Neurinoma
    • Acoustic neuroma
      Acoustic neuroma
      A vestibular schwannoma, often called an acoustic neuroma, is a benign primary intracranial tumor of the myelin-forming cells of the vestibulocochlear nerve . The term "vestibular schwannoma" involves the vestibular portion of the 8th cranial nerve and arises from Schwann cells, which are...

    • Neuroma
      Neuroma
      A neuroma is a growth or tumor of nerve tissue. Just as the Latin word for swelling is now restricted to neoplasias, the equivalent Greek suffix -oma has shared in that fate. Thus, the typical modern usage of neuroma is for nerve tumors...

      , NOS
  • (9580–9589) Granular cell tumors and Alveolar soft part sarcoma
    Sarcoma
    A sarcoma is a cancer that arises from transformed cells in one of a number of tissues that develop from embryonic mesoderm. Thus, sarcomas include tumors of bone, cartilage, fat, muscle, vascular, and hematopoietic tissues...


(9590–9999) Hematologic (Leukemia
Leukemia
Leukemia or leukaemia is a type of cancer of the blood or bone marrow characterized by an abnormal increase of immature white blood cells called "blasts". Leukemia is a broad term covering a spectrum of diseases...

s, Lymphoma
Lymphoma
Lymphoma is a cancer in the lymphatic cells of the immune system. Typically, lymphomas present as a solid tumor of lymphoid cells. Treatment might involve chemotherapy and in some cases radiotherapy and/or bone marrow transplantation, and can be curable depending on the histology, type, and stage...

s and related disorders)
  • (9590–9599) Malignant lymphoma, NOS, Or diffuse
    • Lymphoma
      Lymphoma
      Lymphoma is a cancer in the lymphatic cells of the immune system. Typically, lymphomas present as a solid tumor of lymphoid cells. Treatment might involve chemotherapy and in some cases radiotherapy and/or bone marrow transplantation, and can be curable depending on the histology, type, and stage...

      , NOS
    • Non-Hodgkin's lymphoma, NOS
    • Lymphosarcoma, NOS
  • (9650–9660) Hodgkin's disease
    • Hodgkin's disease, NOS
    • Lymphocyte-rich classical Hodgkin lymphoma
    • Mixed cellularity classical Hodgkin lymphoma
    • Lymphocyte-depleted classical Hodgkin lymphoma
    • Nodular lymphocyte predominant Hodgkin lymphoma
    • Nodular sclerosis classical Hodgkin lymphoma
  • (9670–9680) Malignant lymphoma Specified Type, Diffuse Or Nos
    • Small lymphocytic lymphoma
    • Lymphoplasmacytic lymphoma
    • Mantle cell lymphoma
      Mantle cell lymphoma
      Mantle cell lymphoma is one of the rarest of the non-Hodgkin's lymphomas , comprising about 6% of NHL cases. There are only about 15,000 patients presently in the U.S. While it is difficult to treat and seldom considered cured, investigations into better treatments are actively pursued worldwide...

    • Primary effusion lymphoma
      Primary effusion lymphoma
      -Causes:It is caused by Kaposi's sarcoma-associated herpesvirus , also known as human herpesvirus 8 .In most cases, the lymphoma cells are also infected with Epstein Barr virus ....

    • Mediastinal (thymic) large cell lymphoma
    • Diffuse large B-cell lymphoma or Intravascular large B-cell lymphoma
      Intravascular large B-cell lymphoma
      Intravascular large B-cell lymphoma, abbreviated ILBCL and also referred to as angiotropic large-cell lymphoma, intralymphatic lymphomatosis, intravascular lymphomatosis,, and, less specifically intravascular lymphoma.-Diagnosis:...

    • Burkitt lymphoma
    • Splenic marginal zone lymphoma
      Splenic marginal zone lymphoma
      Splenic marginal zone lymphoma is a lymphoma made up of B-cells that replace the normal architecture of the white pulp of the spleen. The neoplastic cells are both small lymphocytes and larger, transformed blasts, and they invade the mantle zone of splenic follicles and erode the marginal zone,...

  • (9690–9699) Malignant lymphoma, Follicular
    Follicular lymphoma
    Follicular lymphoma is the most common of the indolent non-Hodgkin's lymphomas, and the second most common form of non-Hodgkin's lymphomas overall. It is defined as a lymphoma of follicle center B-cells , which has at least a partially follicular pattern...

     Or Nodular
    Nodule (medicine)
    For use of the term nodule in dermatology, see Nodule In medicine, a nodule refers to a relatively hard, roughly spherical abnormal structure....

    , With Or Without diffuse areas
    • Follicular lymphoma
      Follicular lymphoma
      Follicular lymphoma is the most common of the indolent non-Hodgkin's lymphomas, and the second most common form of non-Hodgkin's lymphomas overall. It is defined as a lymphoma of follicle center B-cells , which has at least a partially follicular pattern...

    • Follicular lymphoma
      Follicular lymphoma
      Follicular lymphoma is the most common of the indolent non-Hodgkin's lymphomas, and the second most common form of non-Hodgkin's lymphomas overall. It is defined as a lymphoma of follicle center B-cells , which has at least a partially follicular pattern...

    • Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue (MALT-lymphoma)
    • Nodal marginal zone B-cell lymphoma
  • (9700–9709) Specified Cutaneous And Peripheral
    Peripheral
    A peripheral is a device attached to a host computer, but not part of it, and is more or less dependent on the host. It expands the host's capabilities, but does not form part of the core computer architecture....

     T-Cell Lymphomas
    • Mycosis fungoides
      Mycosis fungoides
      -External links:* * *...

    • Sezary syndrome
    • Peripheral T-cell lymphoma
      Peripheral T-cell lymphoma
      Peripheral T-cell lymphoma refers to a group of T-cell lymphomas that develop away from the thymus.Examples include:* Cutaneous T-cell lymphomas* Angioimmunoblastic T-cell lymphoma* Extranodal natural killer/T-cell lymphoma, nasal type...

      , unspecified
    • Angioimmunoblastic T-cell lymphoma
      Angioimmunoblastic T-cell lymphoma
      Angioimmunoblastic T-cell lymphoma is a mature T-cell lymphoma with systemic characterized by a polymorphous lymph node infiltrate showing a marked increase in follicular dendritic cells and high endothelial venules and systemic involvement...

    • Subcutaneous panniculitis-like T-cell lymphoma
  • (9710–9719) Other Specified Non-Hodgkin's lymphomas
    • Anaplastic large cell lymphoma
      Anaplastic large cell lymphoma
      Anaplastic large-cell lymphoma is a type of non-Hodgkin lymphoma that features in the World Health Organisation classification of lymphomas.Its name derives from anaplasia and large-cell lymphoma.-Signs and symptoms:...

    • Hepatosplenic T-cell lymphoma
      Hepatosplenic T-cell lymphoma
      Hepatosplenic T-cell lymphoma is a rare and generally incurable form of lymphoma.- Definition :Hepatosplenic T-cell lymphoma is a systemic neoplasm comprising medium-sized cytotoxic T-cells that show a significant sinusoidal infiltration in the liver, spleen, and bone marrow.- Epidemiology :This...

    • Enteropathy type T-cell lymphoma
    • Lymphomatoid papulosis
      Lymphomatoid papulosis
      Lymphomatoid papulosis is a rare skin disorder. The overall prevalence rate of lymphomatoid papulosis is estimated at 1.2 to 1.9 cases per 1,000,000 population.This rare condition has only been studied in depth since 1968.-Presentation:...

    • Primary cutaneous anaplastic large cell lymphoma
    • Extranodal NK/T cell lymphoma, nasal type
  • (9720–9729) Other Lymphoreticular neoplasms
    • Blastic NK cell lymphoma
      Blastic NK cell lymphoma
      Blastic NK cell lymphoma is a type of lymphoma.It is positive for CD4 and CD56.It does not appear to be associated with Epstein Barr virus....

    • Lymphoma
      Lymphoma
      Lymphoma is a cancer in the lymphatic cells of the immune system. Typically, lymphomas present as a solid tumor of lymphoid cells. Treatment might involve chemotherapy and in some cases radiotherapy and/or bone marrow transplantation, and can be curable depending on the histology, type, and stage...

    • Lymphoma
      Lymphoma
      Lymphoma is a cancer in the lymphatic cells of the immune system. Typically, lymphomas present as a solid tumor of lymphoid cells. Treatment might involve chemotherapy and in some cases radiotherapy and/or bone marrow transplantation, and can be curable depending on the histology, type, and stage...

  • (9730–9739) Plasma cell
    Plasma cell
    Plasma cells, also called plasma B cells, plasmocytes, and effector B cells, are white blood cells which produce large volumes of antibodies. They are transported by the blood plasma and the lymphatic system...

     tumors
    • Plasmacytoma
      Plasmacytoma
      Plasmacytoma refers to a malignant plasma cell tumor growing within soft tissue or within the skeleton. The skeletal forms usually have other occult tumors and frequently disseminate to multiple myeloma over the course of 5–10 years. The soft tissue forms most often occur in the upper respiratory...

      , NOS or Extramedullary plasmacytoma or Solitary plasmacytoma of bone
    • Multiple myeloma
      Multiple myeloma
      Multiple myeloma , also known as plasma cell myeloma or Kahler's disease , is a cancer of plasma cells, a type of white blood cell normally responsible for the production of antibodies...

       or Plasma cell myeloma
    • Extraosseous plasmacytoma
  • (9740–9749) Mast cell
    Mast cell
    A mast cell is a resident cell of several types of tissues and contains many granules rich in histamine and heparin...

     Tumors
    • Mastocytoma
      Mastocytoma
      A mastocytoma or mast cell tumor is a type of tumor consisting of mast cells. It is found in humans and many animal species; in human medicine it also can refer to an accumulation or nodule of mast cells that resembles a tumor....

      , NOS or Extracutaneous mastocytoma
      Extracutaneous mastocytoma
      Extracutaneous mastocytoma presents with benign appearing mast cells occurring in sites other than the skin or bone marrow....

    • Mast cell sarcoma
    • Malignant mastocytosis
      Mastocytosis
      Mastocytosis is a group of rare disorders of both children and adults caused by the presence of too many mast cells and CD34+ mast cell precursors in a person's body.- Classification :Mastocytosis can occur in a variety of forms:...

       or Indolent systemic mastocytosis
    • Aggressive systemic mastocytosis or Systemic mastocytosis with associated clonal, hematological non-mast cell lineage disease
    • Mast cell leukemia
      Mast cell leukemia
      Mast cell leukemia is an extremely aggressive subtype of acute myeloid leukemia that usually occurs de novo but can, rarely, evolve from transformation of chronic myeloid leukemia into the more aggressive acute myeloid leukemia. In a small proportion of cases, acute mast cell leukemia may evolve...

    • Langerhans cell histiocytosis
      Langerhans cell histiocytosis
      Langerhans cell Histiocytosis is a rare disease involving clonal proliferation of Langerhans cells, abnormal cells deriving from bone marrow and capable of migrating from skin to lymph nodes...

    • Histiocytic sarcoma
      Histiocytic sarcoma
      Histiocytic sarcoma is a tumor derived from histiocytes. The tumor is often positive for CD163 and can appear in the thyroid....

    • Langerhans cell sarcoma
      Langerhans cell sarcoma
      Langerhans cell sarcoma is a form of malignant histiocytosis. It should not be confused with Langerhans cell histiocytosis, which is cytologically benign. Langerhans cell sarcoma is known to transform into leukemia. It can present in the lung, but such cases are rare....

    • Dendritic cell sarcoma, NOS or Interdigitating dendritic cell sarcoma
      Interdigitating dendritic cell sarcoma
      Interdigitating dendritic cell sarcoma is a form of malignant histiocytosis affecting dendritic cells.It can present in the spleen. It can also present in the duodenum....

      /tumor
    • Follicular dendritic cell sarcoma
      Follicular dendritic cell sarcoma
      Follicular Dendritic Cell Sarcoma is an extremely rare neoplasm. While the existence of FDC tumors was predicted by Lennert in 1978, the tumor wasn’t fully recognized as its own cancer until 1986 after characterization by Monda et. al...

      /tumor
  • (9760–9769) Immunoproliferative diseases
    • Waldenstrom macroglobulinemia
      Waldenström macroglobulinemia
      Waldenström's macroglobulinemia is cancer involving a subtype of white blood cells called lymphocytes. The main attributing antibody is Immunoglobulin M . WM is an "indolent lymphoma,"...

    • Lymphomatoid granulomatosis
      Lymphomatoid granulomatosis
      Lymphomatoid granulomatosis is a neoplastic disease.It is a lymphoproliferative disorder . The word granulomatosis denotes one of its microscopic character, polymorphic lymphoid infiltrates and focal necrosis within it....


-- Lymphoid
Lymphoid
Lymphoid is a term used to describe lymph or the lymphatic system.In the context of lymphoid leukemia, it refers specifically to lymphocytes Lymphoid leukemias and lymphomas are now considered to be tumors of the same type of cell lineage. They are called "leukemia" when in the blood or marrow and...

 leukemias, and related conditions
  • (9800–9809) Leukemias, NOS
    • Leukemia
      Leukemia
      Leukemia or leukaemia is a type of cancer of the blood or bone marrow characterized by an abnormal increase of immature white blood cells called "blasts". Leukemia is a broad term covering a spectrum of diseases...

      , NOS
    • Acute leukemia of ambiguous lineage
    • Acute leukemia
      Acute leukemia
      Acute leukemia or acute leukaemia is a generic term used to describe a family of serious medical conditions relating to an original diagnosis of leukemia...

      , NOS
  • (9820–9829) Lymphoid leukemias
    • Lymphocytic leukemia, NOS
    • Lymphatic leukemia, NOS
    • Acute lymphoblastic leukemia
      Acute lymphoblastic leukemia
      Acute lymphoblastic leukemia is a form of leukemia, or cancer of the white blood cells characterized by excess lymphoblasts.Malignant, immature white blood cells continuously multiply and are overproduced in the bone marrow. ALL causes damage and death by crowding out normal cells in the bone...

      , NOS
    • Acute lymphocytic leukemia
    • Chronic lymphocytic leukemia
      Chronic lymphocytic leukemia
      B-cell chronic lymphocytic leukemia , also known as chronic lymphoid leukemia , is the most common type of leukemia. Leukemias are cancers of the white blood cells . CLL affects B cell lymphocytes. B cells originate in the bone marrow, develop in the lymph nodes, and normally fight infection by...

    • Leukemia
      Leukemia
      Leukemia or leukaemia is a type of cancer of the blood or bone marrow characterized by an abnormal increase of immature white blood cells called "blasts". Leukemia is a broad term covering a spectrum of diseases...

    • Adult T-cell leukemia/lymphoma
  • (9830–9839) Plasma cell
    Plasma cell
    Plasma cells, also called plasma B cells, plasmocytes, and effector B cells, are white blood cells which produce large volumes of antibodies. They are transported by the blood plasma and the lymphatic system...

     leukemia
    Leukemia
    Leukemia or leukaemia is a type of cancer of the blood or bone marrow characterized by an abnormal increase of immature white blood cells called "blasts". Leukemia is a broad term covering a spectrum of diseases...

    • T-cell large granular lymphocytic leukemia
    • B-cell prolymphocytic leukemia
      B-cell prolymphocytic leukemia
      B-cell prolymphocytic leukemia is a more aggressive, but still treatable, form of leukemia. The malignant B cells are larger than average. The name is commonly abbreviated B-PLL.It can involve deletions from chromosome 11 and chromosome 13....

    • T-cell prolymphocytic leukemia
      T-cell prolymphocytic leukemia
      T-cell-prolymphocytic leukemia is a mature T-cell leukemia with aggressive behavior and predilection for blood, bone marrow, lymph nodes, liver, spleen, and skin involvement. T-PLL is a very rare leukemia, primarily affecting adults over the age of 30. It represents 2% of all small lymphocytic...

    • Precursor cell lymphoblastic leukemia, NOS
    • Precursor B lymphoblastic leukemia
    • Precursor T lymphoblastic leukemia

-- Myeloid
Myeloid
The term myeloid suggests an origin in the bone marrow or spinal cord, or a resemblance to the marrow or spinal cord.In hematopoiesis, the term "myeloid cell" is used to describe any leukocyte that is not a lymphocyte...

 leukemias, and related conditions
  • (9840–9849) Erythroleukemias (FAB-M6)
    • Acute erythroid leukemia
  • (9850–9859) Lymphosarcoma cell leukemia
    Leukemia
    Leukemia or leukaemia is a type of cancer of the blood or bone marrow characterized by an abnormal increase of immature white blood cells called "blasts". Leukemia is a broad term covering a spectrum of diseases...

  • (9860–9869) Myeloid (Granulocytic) Leukemias
    • Myeloid leukemia
      Myeloid leukemia
      Myeloid leukemia is a type of leukemia affecting myeloid tissue.Types include:* Acute myeloid leukemia* Chronic myelogenous leukemia...

      , NOS
    • Myelogenous leukemia, NOS
    • Acute myelogenous leukemia (FAB-M1,M2)
    • Chronic myelogenous leukemia
      Chronic myelogenous leukemia
      Chronic myelogenous leukemia , also known as chronic granulocytic leukemia , is a cancer of the white blood cells. It is a form of leukemia characterized by the increased and unregulated growth of predominantly myeloid cells in the bone marrow and the accumulation of these cells in the blood...

    • Acute promyelocytic leukemia
      Acute promyelocytic leukemia
      Acute promyelocytic leukemia is a subtype of acute myelogenous leukemia , a cancer of the blood and bone marrow. It is also known as acute progranulocytic leukemia; APL; AML with t, PML-RARA and variants; FAB subtype M3 and M3 variant.In APL, there is an abnormal accumulation of immature...

        (FAB-M3)
    • Acute promyelocytic leukemia (AML with t(15;17)(q22;q12), PML-RARa and variants)
    • Acute myelomonocytic leukemia
      Leukemia
      Leukemia or leukaemia is a type of cancer of the blood or bone marrow characterized by an abnormal increase of immature white blood cells called "blasts". Leukemia is a broad term covering a spectrum of diseases...

       (FAB-M4)
  • (9870–9889) Basophilic
    Basophilic
    Basophilic is a technical term used by histologists. It describes the microscopic appearance of cells and tissues, as seen down the microscope, after a histological section has been stained with a basic dye. The most common such dye is haematoxylin....

     leukemia
    Leukemia
    Leukemia or leukaemia is a type of cancer of the blood or bone marrow characterized by an abnormal increase of immature white blood cells called "blasts". Leukemia is a broad term covering a spectrum of diseases...

     and Eosinophilic
    Eosinophilic
    Eosinophilic refers to the staining of certain tissues, cells, or organelles after they have been washed with eosin, a dye.Eosin is an acidic dye; thus, the structure being stained is basic....

     leukemia
    Leukemia
    Leukemia or leukaemia is a type of cancer of the blood or bone marrow characterized by an abnormal increase of immature white blood cells called "blasts". Leukemia is a broad term covering a spectrum of diseases...

    • Basophilic
      Basophilic
      Basophilic is a technical term used by histologists. It describes the microscopic appearance of cells and tissues, as seen down the microscope, after a histological section has been stained with a basic dye. The most common such dye is haematoxylin....

       leukemia
      Leukemia
      Leukemia or leukaemia is a type of cancer of the blood or bone marrow characterized by an abnormal increase of immature white blood cells called "blasts". Leukemia is a broad term covering a spectrum of diseases...

       or Acute basophilic leukemia
      Acute basophilic leukemia
      Acute basophilic leukemia is a rare form of acute myeloid leukemia where blasts are accompanied by abnormal basophils in all stages of differentiation...

    • AML with inv(16)(p13q22) or t(16;16)(p13;q22), CBFb/MYH11 (FAB M4Eo)
    • Acute myeloid leukemia
      Acute myeloid leukemia
      Acute myeloid leukemia , also known as acute myelogenous leukemia, is a cancer of the myeloid line of blood cells, characterized by the rapid growth of abnormal white blood cells that accumulate in the bone marrow and interfere with the production of normal blood cells. AML is the most common acute...

      , minimally differentiated
      Cellular differentiation
      In developmental biology, cellular differentiation is the process by which a less specialized cell becomes a more specialized cell type. Differentiation occurs numerous times during the development of a multicellular organism as the organism changes from a simple zygote to a complex system of...

       (FAB type M0)
    • Acute myeloid leukemia
      Acute myeloid leukemia
      Acute myeloid leukemia , also known as acute myelogenous leukemia, is a cancer of the myeloid line of blood cells, characterized by the rapid growth of abnormal white blood cells that accumulate in the bone marrow and interfere with the production of normal blood cells. AML is the most common acute...

      , without maturation (FAB type M1)
    • Acute myeloid leukemia
      Acute myeloid leukemia
      Acute myeloid leukemia , also known as acute myelogenous leukemia, is a cancer of the myeloid line of blood cells, characterized by the rapid growth of abnormal white blood cells that accumulate in the bone marrow and interfere with the production of normal blood cells. AML is the most common acute...

      , with maturation (FAB M2)
    • Chronic myelogenous leukemia
      Chronic myelogenous leukemia
      Chronic myelogenous leukemia , also known as chronic granulocytic leukemia , is a cancer of the white blood cells. It is a form of leukemia characterized by the increased and unregulated growth of predominantly myeloid cells in the bone marrow and the accumulation of these cells in the blood...

    • Atypical chronic myelogenous leukemia
    • Eosinophilic
      Eosinophilic
      Eosinophilic refers to the staining of certain tissues, cells, or organelles after they have been washed with eosin, a dye.Eosin is an acidic dye; thus, the structure being stained is basic....

       leukemia
      Leukemia
      Leukemia or leukaemia is a type of cancer of the blood or bone marrow characterized by an abnormal increase of immature white blood cells called "blasts". Leukemia is a broad term covering a spectrum of diseases...

  • (9890–9899) Monocytic leukemias
    • Monocytic leukemia
      Monocytic leukemia
      Monocytic leukemia is a type of myeloid leukemia characterized by a dominance of monocytes in the marrow. When the monocytic cells are predominantly monoblasts, it is subclassified into monoblastic leukemia....

      , NOS (FAB-M5)
    • Acute monoblastic and monocytic leukemia (FAB M5)
    • Acute myeloid leukemia multilineage dysplasia
    • AML with t(8;21)(q22;q22), AML1/ETO
    • AML with 11q23 (MLL) abnormalities
  • (9900–9948) Other Leukemias
    • Acute megakaryoblastic leukemia
      Acute megakaryoblastic leukemia
      Acute megakaryoblastic leukemia is a form of leukemia where a majority of the blasts are megakaryoblastic.It is classified under M7 in the French-American-British classification....

       (FAB-M7)
    • Acute myeloid leukemia and myelodysplastic syndrome, therapy related
    • Chloroma or Myeloid sarcoma
    • Acute panmyelosis with myelofibrosis
      Acute panmyelosis with myelofibrosis
      Acute panmyelosis with myelofibrosis it is a poorly-defined disorder that arises as either a clonal disorder, or following toxic exposure to the bone marrow...

    • Hairy cell leukemia
      Hairy cell leukemia
      Hairy cell leukemia is an uncommon hematological malignancy characterized by an accumulation of abnormal B lymphocytes. It is usually classified as a sub-type of chronic lymphoid leukemia...

    • Juvenile myelomonocytic leukemia
      Juvenile myelomonocytic leukemia
      Juvenile myelomonocytic leukemia is a serious chronic leukemia that affects children mostly aged 4 and younger. The average age of patients at diagnosis is 2 years old. The World Health Organization has included JMML in the category of Myelodysplastic and Myeloproliferative disorders...

    • Aggressive NK cell leukemia

-- Other
  • (9950–9970) Miscellaneous Myeloproliferative And Lymphoproliferative disorders
    Lymphoproliferative disorders
    Lymphoproliferative disorders refer to several conditions in which lymphocytes are produced in excessive quantities. They typically occur in patients who have compromised immune systems...

    • Polycythemia vera
      Polycythemia vera
      Polycythemia vera is a blood disorder in which the bone marrow makes too many red blood cells. It may also result in the overproduction of white blood cells and platelets. Most of the health concerns associated with polycythemia vera are caused by the blood being thicker as a result of the...

    • Myeloproliferative disease
      Myeloproliferative disease
      The myeloproliferative diseases are a group of diseases of the bone marrow in which excess cells are produced. They are related to, and may evolve into, myelodysplastic syndrome and acute myeloid leukemia, although the myeloproliferative diseases on the whole have a much better prognosis than...

      , NOS
    • Chronic idiopathic myelofibrosis
      Myelofibrosis
      Myelofibrosis, also known as myeloid metaplasia, chronic idiopathic myelofibrosis, osteomyelofibrosis and primary myelofibrosis is a disorder of the bone marrow...

    • Essential thrombocytemia
    • Chronic neutrophilic leukemia
      Chronic neutrophilic leukemia
      Chronic neutrophilic leukemia is a rare myeloproliferative disorder that features a persistent neutrophilia in peripheral blood, myeloid hyperplasia in bone marrow, hepatosplenomegaly, and the absence of the Philadelphia chromosome or a BCR/ABL fusion gene.-Epidemiology:This is a rare disease,...

    • Chronic eosinophilic leukemia
      Chronic eosinophilic leukemia
      Chronic eosinophilic leukemia is a disease in which too many eosinophils are found in the bone marrow, blood, and other tissues. CEL may stay the same for many years, or it may progress quickly to acute leukemia. It is generally caused by overactivation of the oncogene PDGFRA through a chromosome...

       / hypereosinophilic syndrome
      Hypereosinophilic syndrome
      The hypereosinophilic syndrome is a disease characterized by a persistently elevated eosinophil count in the blood for at least six months without any recognizable cause, with involvement of either the heart, nervous system, or bone marrow.HES is a diagnosis of exclusion, after clonal...

    • Post-transplant lymphoproliferative disorder, pleomorphic
    • Chronic Myeloproliferative disease, unclassifiable
    • Myelodysplastic / myeloproliferative diseases, unclassifiable
  • (9980–9989) Myelodysplastic syndrome
    Myelodysplastic syndrome
    The myelodysplastic syndromes are a diverse collection of hematological medical conditions that involve ineffective production of the myeloid class of blood cells....

    • Chronic myelomonocytic leukemia
      Chronic myelomonocytic leukemia
      Chronic myelomonocytic leukemia is a form of leukemia featuring monocytosis.The categorization of this disease has been controversial. Patients with CMML can present with various clinical features, mimicking either myelodysplastic syndroms or myeloproliferative neoplasms depending upon a patient's...

       or Refractory anemia
    • Refractory anemia with ringed sideroblasts
    • Refractory anemia with excess blasts
    • Refractory cytopenia with multilineage dysplasia
      Refractory cytopenia with multilineage dysplasia
      Refractory cytopenia with multilineage dysplasia is a form of myelodysplastic syndrome.It is abbreviated "RCMD"....

    • Myelodysplastic syndrome associated with isolated del(5q) chromosome abnormality
    • Myelodysplastic syndrome
      Myelodysplastic syndrome
      The myelodysplastic syndromes are a diverse collection of hematological medical conditions that involve ineffective production of the myeloid class of blood cells....

      , NOS

Topography

The topography axis is for the topographical codes
Topographical codes
In medicine, "topographical codes" are codes that indicate a specific location in the body.-Examples:Only the first of these is a system dedicated only to topography. The others are more generalized systems that contain topographic axes.* Nomina Anatomica * ICD-O* SNOMED* MeSH...

 of the tumor's site. It is standardized with the C section of ICD-10
ICD
The International Statistical Classification of Diseases and Related Health Problems is a medical classification that provides codes to classify diseases and a wide variety of signs, symptoms, abnormal findings, complaints, social circumstances, and external causes of injury or disease...



There were no changes in the topography axis between ICD-O-2 and ICD-O-3.

See List of ICD-10 codes#(C00–C97) Malignant Neoplasms for examples.

External links

  • Official page at World Health Organization
    World Health Organization
    The World Health Organization is a specialized agency of the United Nations that acts as a coordinating authority on international public health. Established on 7 April 1948, with headquarters in Geneva, Switzerland, the agency inherited the mandate and resources of its predecessor, the Health...

  • Tutorial at National Cancer Institute
    National Cancer Institute
    The National Cancer Institute is part of the National Institutes of Health , which is one of 11 agencies that are part of the U.S. Department of Health and Human Services. The NCI coordinates the U.S...

  • Overview at DIMDI
  • Overview of multiple primaries at healthyarkansas.com (PPT)
  • History of versions at National Cancer Institute
    National Cancer Institute
    The National Cancer Institute is part of the National Institutes of Health , which is one of 11 agencies that are part of the U.S. Department of Health and Human Services. The NCI coordinates the U.S...


Morphology

  • Cancer.gov – overview, includes link to Excel spreadsheet with codes at National Cancer Institute
    National Cancer Institute
    The National Cancer Institute is part of the National Institutes of Health , which is one of 11 agencies that are part of the U.S. Department of Health and Human Services. The NCI coordinates the U.S...

  • Overview at National Cancer Institute
    National Cancer Institute
    The National Cancer Institute is part of the National Institutes of Health , which is one of 11 agencies that are part of the U.S. Department of Health and Human Services. The NCI coordinates the U.S...

  • Word document – malignancies only at National Cancer Institute
    National Cancer Institute
    The National Cancer Institute is part of the National Institutes of Health , which is one of 11 agencies that are part of the U.S. Department of Health and Human Services. The NCI coordinates the U.S...

  • Overview at University hospital Gießen und Marburg
    University hospital Gießen und Marburg
    The University Hospital Gießen and Marburg is a German university hospital based in Marburg and Gießen...

  • Download table German version at DIMDI
  • Codes at IARC
    International Agency for Research on Cancer
    The International Agency for Research on Cancer is an intergovernmental agency forming part of the World Health Organisation of the United Nations....

  • 1st, 2nd, and 3rd editions at wolfbane.com
  • List at The National Cancer Registry Ireland
  • List at London School of Hygiene & Tropical Medicine
    London School of Hygiene & Tropical Medicine
    The London School of Hygiene & Tropical Medicine is a constituent college of the federal University of London, specialising in public health and tropical medicine...

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