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Hydrolyzed collagen (hydrolysate)

 

 
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Hydrolyzed collagen (hydrolysate)
 
 
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Hydrolyzed collagen, HCP, (also known as purified gelatin
Gelatin

Gelatin is a translucent, colorless, brittle, nearly tasteless solid, derived from the collagen inside animals' skin and mostly bones. It has been commonly used as a gelling agent in food, pharmaceutical, photography, and cosmetic manufacturing....
 and collagen hydrolysate) is collagen that has been enzymatically or chemically processed to make it more digestible and more easily absorbed by the body. HCP is often used by body builders because it is a relatively inexpensive protein
Protein

Proteins are organic compounds made of amino acids arranged in a linear chain and joined together by peptide bonds between the carboxyl and amino groups of adjacent amino acid Residue ....
 source. It is also used to treat skin disorders, treat or prevent malnutrition and for those who cannot tolerate large amounts of bulk food, such as patients of weight loss surgery.

Collagen
Collagen

Collagen is the main protein of connective tissue in animals and the most abundant protein in mammals, making up about 25% to 35% of the whole-body protein content....
 is the primary structural protein found in the connective tissue
Connective tissue

Connective tissue is a form of fibrous biological tissue.It is one of the four types of tissue in traditional classifications .Collagen is the main protein of connective tissue in animals and the most abundant protein in mammals, making up about 25% of the total protein content....
s in the body (including the skin, bones, cartilage
Cartilage

Cartilage is a type of dense connective tissue. It is composed of specialized cells called chondrocyte that produce a large amount of extracellular matrix composed of collagen fibers, abundant ground substance rich in proteoglycan, and elastin fibers....
, tendon
Tendon

A tendon is a tough band of fibrous connective tissue that usually connects muscle to bone and is capable of withstanding tension . Tendons are similar to ligaments except that ligaments join one bone to another....
s, and ligament
Ligament

Ligaments connect bone to bone. In anatomy, the term ligament is used to denote three different types of structures:# Fibrous Tissue that connects bones to other bones....
s), and commercially it is derived from either fish (marine sources), beef (bovine sources), or pig (porcine sources).






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Hydrolyzed collagen, HCP, (also known as purified gelatin
Gelatin

Gelatin is a translucent, colorless, brittle, nearly tasteless solid, derived from the collagen inside animals' skin and mostly bones. It has been commonly used as a gelling agent in food, pharmaceutical, photography, and cosmetic manufacturing....
 and collagen hydrolysate) is collagen that has been enzymatically or chemically processed to make it more digestible and more easily absorbed by the body. HCP is often used by body builders because it is a relatively inexpensive protein
Protein

Proteins are organic compounds made of amino acids arranged in a linear chain and joined together by peptide bonds between the carboxyl and amino groups of adjacent amino acid Residue ....
 source. It is also used to treat skin disorders, treat or prevent malnutrition and for those who cannot tolerate large amounts of bulk food, such as patients of weight loss surgery.

Collagen
Collagen

Collagen is the main protein of connective tissue in animals and the most abundant protein in mammals, making up about 25% to 35% of the whole-body protein content....
 is the primary structural protein found in the connective tissue
Connective tissue

Connective tissue is a form of fibrous biological tissue.It is one of the four types of tissue in traditional classifications .Collagen is the main protein of connective tissue in animals and the most abundant protein in mammals, making up about 25% of the total protein content....
s in the body (including the skin, bones, cartilage
Cartilage

Cartilage is a type of dense connective tissue. It is composed of specialized cells called chondrocyte that produce a large amount of extracellular matrix composed of collagen fibers, abundant ground substance rich in proteoglycan, and elastin fibers....
, tendon
Tendon

A tendon is a tough band of fibrous connective tissue that usually connects muscle to bone and is capable of withstanding tension . Tendons are similar to ligaments except that ligaments join one bone to another....
s, and ligament
Ligament

Ligaments connect bone to bone. In anatomy, the term ligament is used to denote three different types of structures:# Fibrous Tissue that connects bones to other bones....
s), and commercially it is derived from either fish (marine sources), beef (bovine sources), or pig (porcine sources). Hydrolyzed collagen consists of water-soluble peptide
Peptide

Peptides are short polymers formed from the linking, in a defined order, of a-amino acids. The link between one amino acid residue and the next is known as an amide chemical bond or a peptide bond....
s which are rich sources of the amino acids glycine
Glycine

Glycine is the organic compound with the chemical formula NH2CH2COOH. It is the smallest of the 20 amino acids commonly found in proteins, coded by codons GGU, GGC, GGA and GGG....
, L-proline
Proline

Proline is an a-amino acid, one of the twenty DNA-encoded amino acids. Its codons are CCU, CCC, CCA, and CCG. It is not an essential amino acid, which means that humans can synthesize it....
 and L-hydroxyproline
Hydroxyproline

4-Hydroxyproline, or hydroxyproline , is an uncommon amino acid, abbreviated as HYP, e.g., in Protein Data Bank....
. Nutritional supplements containing hydrolyzed collagen are typically marketed for osteoporosis
Osteoporosis

Osteoporosis is a disease of bone that leads to an increased risk of bone fracture. In osteoporosis the bone mineral density is reduced, bone microarchitecture is disrupted, and the amount and variety of collagen proteins in bone is altered....
, osteoarthritis
Osteoarthritis

Osteoarthritis , is a group of diseases and mechanical abnormalities entailing degradation of joints, including articular cartilage and the subchondral bone next to it....
, rheumatoid arthritis
Rheumatoid arthritis

Rheumatoid arthritis is a chronic, systemic disease inflammation that may affect many tissues and organs, but principally attacks the joints producing a inflammatory synovitis that often progresses to destruction of the articular cartilage and ankylosis of the joints....
, weight loss
Weight loss

Weight loss, in the context of medicine or health or physical fitness, is a reduction of the total body weight, due to a mean loss of fluid, body fat or adipose tissue and/or lean mass, namely bone mineral deposits, muscle, tendon and other connective tissue....
, and to assist in recovery from exercise and sports-related injuries, although scientific data in these areas is sparse.

HCP has been used by European health practitioners for decades as an alternative treatment for arthritis and osteoporosis. German and Czech studies cite the use of 7-10 grams of HCP daily to decrease pain and stiffness associated with arthritis.

The taking of the nutritional supplements Collagen Hydrolysate can prevent a cartilage degeneration and soothe arthritis. Dr. Steffen Oesser from the University Kiel has reported during the orthopaedics convention in Berlin and explained it with studies.

The amino acid composition of Collagen Hydrolysate is equivalent in the cartilage matrix. From the Collagen Hydrolysate there will fragment reabsorbs after the taking and enriched in the joint cartilage. The fragments stimulate dose depending the biosynthesis of type II collagen there, as Oesser reported during thea symposium. The researcher could cover to cartilage cell cultures that Collagen Hydrolysate increases the collagen production of cells admitted in comparison with untreated cells around two and a half times. From the intestine reabsorbing and into the cartilage fabric taken Collagen-fragments have apparently the same effect as natural collagen degradation products: They stimulate the new synthesis of collagen and counteract a wear on the cartilage matrix.

Cultivated cartilage cells also produced more proteoglycans after the bonus of collagen hydrolysate, says the biochemist. Oesser:"Under influence of collagen hydrolysate the most important components of the extra cellular cartilage matrix are therefore established". This is important to the quality and durability of the cartilage. Taken Collagen hydrolysate therefore prevents presumably degenerative joint diseases, says Oesser. There are references to it also from clinical studies in which patients had taken part with pains and stiffness in the knee. From the majority of the patients the complaints were decreased considerably.

And the capacity of the joint areas as well as the strength of the surrounding fabric increased under a therapy of several months with a 10 mg collagen hydrolysate daily, as Oesser reported. The nutritional supplement is well wholesome and can be taken by patients with high arthrosis risk, by approximately overweight or in sports for prevention also.

Hydrolyzed collagen has also been found as a component in protein based hair conditioners. These HCP hair products are usually leave in treatments used to keep hair from breaking.

Sources