Gene dosage
Encyclopedia
Gene dosage is the number of copies of a gene
present in a cell or nucleus
. An increase in gene dosage can cause higher levels of gene product if the gene is not subject to regulation from elsewhere in the body.
Gene
A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a type of protein or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains...
present in a cell or nucleus
Cell nucleus
In cell biology, the nucleus is a membrane-enclosed organelle found in eukaryotic cells. It contains most of the cell's genetic material, organized as multiple long linear DNA molecules in complex with a large variety of proteins, such as histones, to form chromosomes. The genes within these...
. An increase in gene dosage can cause higher levels of gene product if the gene is not subject to regulation from elsewhere in the body.