Fundic glands
Encyclopedia
The fundus glands are found in the body
and fundus
of the stomach
.
They are simple tubes, two or more of which open into a single duct.
is a medical syndrome where the fundus
of the stomach
develops many polyps
.
Body of stomach
The Body of the Stomach often just called the body or corpus is an anatomical region of the stomach in humans....
and fundus
Fundus (stomach)
The fundus of the stomach is the left portion of the stomach's body, and is marked off from the remainder of the body by a plane passing horizontally through the cardiac orifice....
of the stomach
Stomach
The stomach is a muscular, hollow, dilated part of the alimentary canal which functions as an important organ of the digestive tract in some animals, including vertebrates, echinoderms, insects , and molluscs. It is involved in the second phase of digestion, following mastication .The stomach is...
.
They are simple tubes, two or more of which open into a single duct.
Pathology
Fundic gland polyposisFundic gland polyposis
Fundic gland polyposis is a medical syndrome where the fundus of the stomach develops many polyps. The condition has been described both in patients with polyposis conditions of the colon , and in patients in whom it occurs sporadically.-Clinical presentation:Most patients with fundic gland...
is a medical syndrome where the fundus
Fundus (stomach)
The fundus of the stomach is the left portion of the stomach's body, and is marked off from the remainder of the body by a plane passing horizontally through the cardiac orifice....
of the stomach
Stomach
The stomach is a muscular, hollow, dilated part of the alimentary canal which functions as an important organ of the digestive tract in some animals, including vertebrates, echinoderms, insects , and molluscs. It is involved in the second phase of digestion, following mastication .The stomach is...
develops many polyps
Polyp (medicine)
A polyp is an abnormal growth of tissue projecting from a mucous membrane. If it is attached to the surface by a narrow elongated stalk, it is said to be pedunculated. If no stalk is present, it is said to be sessile. Polyps are commonly found in the colon, stomach, nose, sinus, urinary bladder...
.
Types of cells
| Location | Name | Description | Secretion | Staining >- | Isthmus |
Mucous neck cells | In gastric pits Gastric pits Gastric pits are indentations in the stomach which denote entrances to the tubular shaped gastric glands. They are deeper in the pylorus than they are in the other parts of the stomach. The human stomach has several million of these pits which dot the surface of the lining epithelium... . |
mucus Mucus In vertebrates, mucus is a slippery secretion produced by, and covering, mucous membranes. Mucous fluid is typically produced from mucous cells found in mucous glands. Mucous cells secrete products that are rich in glycoproteins and water. Mucous fluid may also originate from mixed glands, which... gel layer |
>- | parietal (oxyntic) cell Parietal cell Parietal cells, or oxyntic cells, are the stomach epithelium cells that secrete gastric acid and intrinsic factor.Acetylcholine and gastrin . The histamine receptors act by increasing intracellular cAMP, whereas the muscarinic and gastrin receptors increase intracellular Ca2+ levels... s |
Between the chief cells and the basement membrane Basement membrane The basement membrane is a thin sheet of fibers that underlies the epithelium, which lines the cavities and surfaces of organs including skin, or the endothelium, which lines the interior surface of blood vessels.- Composition :... , larger oval cells, which stain deeply with eosin Eosin Eosin is a fluorescent red dye resulting from the action of bromine on fluorescein. It can be used to stain cytoplasm, collagen and muscle fibers for examination under the microscope. Structures that stain readily with eosin are termed eosinophilic.... , are found; these cells are studded throughout the tube at intervals, giving it a beaded or varicose appearance. These are known as the parietal cells or oxyntic cells, and they are connected with the lumen Lumen (anatomy) A lumen in biology is the inside space of a tubular structure, such as an artery or intestine... by fine channels which run into their substance. |
gastric acid Gastric acid Gastric acid is a digestive fluid, formed in the stomach. It has a pH of 1 to 2 and is composed of hydrochloric acid , and large quantities of potassium chloride and sodium chloride... and intrinsic factor Intrinsic factor Intrinsic factor also known as gastric intrinsic factor is a glycoprotein produced by the parietal cells of the stomach. It is necessary for the absorption of vitamin B12 later on in the small intestine... |
>- | chief (zymogenic) cell Gastric chief cell A gastric chief cell is a cell in the stomach that releases pepsinogen, gastric lipase and Chymosin... s |
At the point where they open into the duct, which is termed the neck, the epithelium Epithelium Epithelium is one of the four basic types of animal tissue, along with connective tissue, muscle tissue and nervous tissue. Epithelial tissues line the cavities and surfaces of structures throughout the body, and also form many glands. Functions of epithelial cells include secretion, selective... alters, and consists of short columnar or polyhedral, granular cells, which almost fill the tube, so that the lumen becomes suddenly constricted and is continued down as a very fine channel. They are known as the chief cells or central cells of the glands. |
pepsinogen, rennin | Basophilic Basophilic Basophilic is a technical term used by histologists. It describes the microscopic appearance of cells and tissues, as seen down the microscope, after a histological section has been stained with a basic dye. The most common such dye is haematoxylin.... >- | Base |
enteroendocrine (APUD) cells Enteroendocrine cells Enteroendocrine cells are specialized endocrine cells of the gastrointestinal tract. They produce hormones such as serotonin, somatostatin, motilin, cholecystokinin, gastric inhibitory peptide, neurotensin, vasoactive intestinal peptide, and enteroglucagon.... |
G cells are a type of enteroendocrine cell that secrete the hormone gastrin (gastrin promotes the secretion of pepsinogen (by chief cells) and HCl (by parietal cells) and promotes gastric contractions to mix contents). | hormones | - |
External links
- "Fundic stomach" - "Mammal, ruminant stomach (LM, High)" - "Digestive System: Alimentary Canal - fundic stomach"- Veterinary Histology at vt.edu - see slide #42