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Fructose 1,6-bisphosphate

 

 
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Fructose 1,6-bisphosphate
 
 
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Fructose 1,6-phosphate is fructose
Fructose

Fructose is a simple Reducing sugar sugar found in many foods and is one of the three important dietary monosaccharides along with glucose and galactose....
 sugar phosphorylated on carbons 1 and 6 (ie. is a fructosephosphate). The ß-D-form of this compound is very common in cells
Cell (biology)

The cell is the structural and functional unit of all known Life organisms. It is the smallest unit of an organism that is classified as living, and is often called the building bricks of life....
. The vast majority of glucose
Glucose

Glucose , a monosaccharide also known as grape sugar, blood sugar, or corn sugar, is a very important carbohydrate in biology....
 and fructose entering a cell will become converted to fructose 1,6-phosphate at some point.

Fructose 1,6-phosphate in glycolysis
Fructose 1,6-phosphate lies within the glycolysis
Glycolysis

Glycolysis is the metabolic pathway that converts glucose, C6H12O6, into pyruvate, C3H5O3-....
 metabolic pathway
Metabolic pathway

In biochemistry, a metabolic pathway is a series of chemistry reactions occurring within a cell . In each pathway, a principal chemical is modified by chemical reactions....
 and is produced by phosphorylation of fructose 6-phosphate
Fructose 6-phosphate

Fructose 6-phosphate is fructose sugar phosphorylated on carbon 6 . The ?-D-form of this compound is very common in cell . The vast majority of glucose and fructose entering a cell will become converted to this at some point....
.






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Fructose 1,6-phosphate is fructose
Fructose

Fructose is a simple Reducing sugar sugar found in many foods and is one of the three important dietary monosaccharides along with glucose and galactose....
 sugar phosphorylated on carbons 1 and 6 (ie. is a fructosephosphate). The ß-D-form of this compound is very common in cells
Cell (biology)

The cell is the structural and functional unit of all known Life organisms. It is the smallest unit of an organism that is classified as living, and is often called the building bricks of life....
. The vast majority of glucose
Glucose

Glucose , a monosaccharide also known as grape sugar, blood sugar, or corn sugar, is a very important carbohydrate in biology....
 and fructose entering a cell will become converted to fructose 1,6-phosphate at some point.

Fructose 1,6-phosphate in glycolysis


Fructose 1,6-phosphate lies within the glycolysis
Glycolysis

Glycolysis is the metabolic pathway that converts glucose, C6H12O6, into pyruvate, C3H5O3-....
 metabolic pathway
Metabolic pathway

In biochemistry, a metabolic pathway is a series of chemistry reactions occurring within a cell . In each pathway, a principal chemical is modified by chemical reactions....
 and is produced by phosphorylation of fructose 6-phosphate
Fructose 6-phosphate

Fructose 6-phosphate is fructose sugar phosphorylated on carbon 6 . The ?-D-form of this compound is very common in cell . The vast majority of glucose and fructose entering a cell will become converted to this at some point....
. It is in turn broken down into two compounds; glyceraldehyde 3-phosphate
Glyceraldehyde 3-phosphate

Glyceraldehyde 3-phosphate, also known as triose phosphate or 3-phosphoglyceraldehyde and abbreviated as G3P, GADP, GAP, TP, GALP or PGAL, is a chemical compound that occurs as an intermediate in several central metabolic pathways of all organisms....
 and dihydroxyacetone phosphate. It is an allosteric activator of pyruvate kinase
Pyruvate kinase

Pyruvate kinase is an enzyme involved in glycolysis. It catalyst the transfer of a phosphate group from phosphoenolpyruvate to adenosine diphosphate, yielding one molecule of pyruvate and one molecule of adenosine triphosphate....
.



The numbering of the carbon atoms indicates the fate of the carbons according to their position in fructose 6-phosphate.

Fructose 1,6-phosphate isomerism


Fructose 1,6-phosphate has only one biologically active isomer
Isomer

In chemistry, isomers are compounds with the same molecular formula but different structural formulae. Isomers do not necessarily share similar properties unless they also have the same functional groups....
, the ß-D-form. There are many other isomers, analogous to those of fructose.

See also

  • Fructose 2,6-bisphosphate
    Fructose 2,6-bisphosphate

    Fructose 2,6-bisphosphate , abbreviated Fru-2,6-P2, is a metabolite which allosterically affects the activity of the enzymes phosphofructokinase 1 and fructose 1,6-bisphosphatase to regulate glycolysis and gluconeogenesis....