Frank W. Crowe
Encyclopedia
Frank W. Crowe was an American
physician
remembered for the Crowe sign
in neurofibromatosis
.
In 1956 Crowe et al. recognised the autosomal dominant heredity of neurofibromatosis and the use of 6 or more café au lait spot
s to diagnose the condition. In 1964 Crowe published work on the use of axillary freckling in its diagnosis, which is now referred to as the Crowe sign.
United States
The United States of America is a federal constitutional republic comprising fifty states and a federal district...
physician
Physician
A physician is a health care provider who practices the profession of medicine, which is concerned with promoting, maintaining or restoring human health through the study, diagnosis, and treatment of disease, injury and other physical and mental impairments...
remembered for the Crowe sign
Crowe sign
The Crowe sign or Crowe's sign is the presence of axillary freckling in people with neurofibromatosis type I . These freckles occur in up to 30% of people with the disease and their presence is one of seven diagnostic criteria for neurofibromatosis...
in neurofibromatosis
Neurofibromatosis
Neurofibromatosis is a genetically-inherited disorder in which the nerve tissue grows tumors that may be benign or may cause serious damage by compressing nerves and other tissues...
.
In 1956 Crowe et al. recognised the autosomal dominant heredity of neurofibromatosis and the use of 6 or more café au lait spot
Café au lait spot
Café au lait spots or Café au lait macules are pigmented birthmarks. The name café au lait is French for "milky coffee" and refers to their light-brown color...
s to diagnose the condition. In 1964 Crowe published work on the use of axillary freckling in its diagnosis, which is now referred to as the Crowe sign.