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Ex vivo (Latin: out of the living) means that which takes place outside an organism. In science, ex vivo refers to experimentation or measurements done in or on living tissue in an artificial environment outside the organism with the minimum alteration of the natural conditions. The most common "ex vivo" procedures involve living cells or tissues taken from an organism and cultured in a laboratory apparatus, usually under sterile conditions and no alterations done for a few hours up to 24 hrs.






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Ex vivo (Latin: out of the living) means that which takes place outside an organism. In science, ex vivo refers to experimentation or measurements done in or on living tissue in an artificial environment outside the organism with the minimum alteration of the natural conditions. The most common "ex vivo" procedures involve living cells or tissues taken from an organism and cultured in a laboratory apparatus, usually under sterile conditions and no alterations done for a few hours up to 24 hrs. Experiments lasting longer than this using living cells or tissue are typically considered to be "in vitro". Ex-vivo conditions allow experimentation under highly controlled conditions impossible in the intact organism, albeit at the expense of looking at the tissue in its "natural" environment. One widely performed ex vivo study is the chick chorioallantoic membrane (CAM) assay. In this assay, angiogenesis
Angiogenesis

Angiogenesis is a physiological process involving the growth of new blood vessels from pre-existing vessels. Though there has been some debate over this, vasculogenesis is the term used for spontaneous blood-vessel formation, and Intussusception is the term for new blood vessel formation by splitting off existing ones....
 is promoted on the CAM membrane of a chick embryo outside the organism (chicken). Ex vivo studies are usually performed in vitro
In vitro

In vitro refers to the technique of performing a given procedure in a controlled environment outside of a living organism. Some may argue that in vitro refers to a process that is created in a "test tube"; however, Robert Kail and John Cavanaugh on page 58 in the 4th edition of Human Development: A Life-Span View cite that in fact th...
, although the use of these two terms is not synonymous.

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  • in vitro
    In vitro

    In vitro refers to the technique of performing a given procedure in a controlled environment outside of a living organism. Some may argue that in vitro refers to a process that is created in a "test tube"; however, Robert Kail and John Cavanaugh on page 58 in the 4th edition of Human Development: A Life-Span View cite that in fact th...
  • in vivo
    In vivo

    In vivo means that which takes place inside an organism. In science, in vivo refers to experimentation done in or on the living tissue of a whole, living organism as opposed to a partial or dead one or a in vitro....
  • in silico
    In silico

    In silico is an expression used to mean "performed on computer or via computer simulation." The phrase is coined in analogy to the Latin language phrases in vivo and in vitro which are commonly used in biology and refer to experiments done in living organisms and outside of living organisms, respectively....