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Edward B. Lewis

 

 
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Edward B. Lewis (May 20, 1918 – July 21, 2004) was an American
United States

The United States of America is a Federal government constitutional republic comprising U.S. state and a federal district. The country is situated mostly in central North America, where its Contiguous United States and Washington, D.C., the Capital districts and territories, lie between the Pacific Ocean and Atlantic Oceans, Borders of the U...
 geneticist
Geneticist

A geneticist is a scientist who studies genetics, the science of heredity and genetic variation of organisms. A geneticist can be employed as a researcher or lecturer....
, a corecipient of the 1995 Nobel Prize in Physiology or Medicine
Nobel Prize in Physiology or Medicine

The Nobel Prize in Physiology or Medicine is awarded once a year by the Swedish Karolinska Institutet. It is one of the five Nobel Prizes established by the will of Alfred Nobel in 1895, awarded for outstanding contributions in Nobel Prize in Physics, Nobel Prize in Chemistry, Nobel Prize in Literature, Nobel Peace Prize, and Physiology or Medic...
.

Lewis was born in Wilkes-Barre, Pennsylvania
Wilkes-Barre, Pennsylvania

Wilkes-Barre is a city in Northeastern Pennsylvania Pennsylvania, United States. It is the county seat of Luzerne County, Pennsylvania and the central city of the Wyoming Valley....
 and graduated from E.L. Meyers High School. He received a BA in Biostatistics from the University of Minnesota
University of Minnesota

The University of Minnesota, Twin Cities is a public university research university located in Minneapolis and St. Paul, Minnesota, Minnesota, United States....
 in 1939, where he worked on Drosophila melanogaster
Drosophila melanogaster

Drosophila melanogaster is a two-winged insect that belongs to the Diptera, the Order of the Fly. The species is commonly known as the Drosophilidae or vinegar fly, and is one of the most commonly used model organisms in biology, including studies in genetics, physiology and Life history theory....
 in the lab of C.P. Oliver. In 1942 Lewis received a Ph.D. from California Institute of Technology
California Institute of Technology

The California Institute of Technology is a private university research university located in Pasadena, California, United States. Caltech maintains a strong emphasis on the natural sciences and engineering....
 (Caltech), working under the guidance of Alfred Sturtevant
Alfred Sturtevant

Alfred Henry Sturtevant was an United States geneticist. Sturtevant constructed the first genetic map of a chromosome in 1913. Throughout his career he worked on the organism Drosophila melanogaster with Thomas Hunt Morgan....
. After serving as a meteorologist in the U.S.






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Edward B. Lewis (May 20, 1918 – July 21, 2004) was an American
United States

The United States of America is a Federal government constitutional republic comprising U.S. state and a federal district. The country is situated mostly in central North America, where its Contiguous United States and Washington, D.C., the Capital districts and territories, lie between the Pacific Ocean and Atlantic Oceans, Borders of the U...
 geneticist
Geneticist

A geneticist is a scientist who studies genetics, the science of heredity and genetic variation of organisms. A geneticist can be employed as a researcher or lecturer....
, a corecipient of the 1995 Nobel Prize in Physiology or Medicine
Nobel Prize in Physiology or Medicine

The Nobel Prize in Physiology or Medicine is awarded once a year by the Swedish Karolinska Institutet. It is one of the five Nobel Prizes established by the will of Alfred Nobel in 1895, awarded for outstanding contributions in Nobel Prize in Physics, Nobel Prize in Chemistry, Nobel Prize in Literature, Nobel Peace Prize, and Physiology or Medic...
.

Lewis was born in Wilkes-Barre, Pennsylvania
Wilkes-Barre, Pennsylvania

Wilkes-Barre is a city in Northeastern Pennsylvania Pennsylvania, United States. It is the county seat of Luzerne County, Pennsylvania and the central city of the Wyoming Valley....
 and graduated from E.L. Meyers High School. He received a BA in Biostatistics from the University of Minnesota
University of Minnesota

The University of Minnesota, Twin Cities is a public university research university located in Minneapolis and St. Paul, Minnesota, Minnesota, United States....
 in 1939, where he worked on Drosophila melanogaster
Drosophila melanogaster

Drosophila melanogaster is a two-winged insect that belongs to the Diptera, the Order of the Fly. The species is commonly known as the Drosophilidae or vinegar fly, and is one of the most commonly used model organisms in biology, including studies in genetics, physiology and Life history theory....
 in the lab of C.P. Oliver. In 1942 Lewis received a Ph.D. from California Institute of Technology
California Institute of Technology

The California Institute of Technology is a private university research university located in Pasadena, California, United States. Caltech maintains a strong emphasis on the natural sciences and engineering....
 (Caltech), working under the guidance of Alfred Sturtevant
Alfred Sturtevant

Alfred Henry Sturtevant was an United States geneticist. Sturtevant constructed the first genetic map of a chromosome in 1913. Throughout his career he worked on the organism Drosophila melanogaster with Thomas Hunt Morgan....
. After serving as a meteorologist in the U.S. Air Force in World War II
World War II

World War II, or the Second World War , was a global military conflict which involved a Participants in World War II, including all of the great powers, organised into two opposing military alliances: the Allies of World War II and the Axis powers....
, Lewis joined the Caltech faculty in 1946 as an instructor. In 1956 he was appointed Professor of Biology, and in 1966 the Thomas Hunt Morgan
Thomas Hunt Morgan

Thomas Hunt Morgan was an American genetics and Embryology. Morgan received his PhD from Johns Hopkins University in 1890 and researched embryology during his tenure at Bryn Mawr College....
 Professor of Biology. Among his many awards were the Thomas Hunt Morgan Medal (1983), the Gairdner Foundation International award (1987), the Wolf Foundation prize in medicine (1989), the Rosenstiel award (1990), the National Medal of Science
National Medal of Science

The National Medal of Science is an honor bestowed by the President of the United States to individuals in science and engineering who have made important contributions to the advancement of knowledge in the fields of behavioral science and social sciences, biology, chemistry, engineering, mathematics and physics....
 (1990), the Albert Lasker Award for Basic Medical Research
Albert Lasker Award for Basic Medical Research

The Albert Lasker Award for Basic Medical Research is one of the Lasker Award awarded by the Lasker Foundation for the understanding, diagnosis, prevention, treatment, and cure of disease....
 (1991), and the Louisa Gross Horwitz Prize
Louisa Gross Horwitz Prize

Louisa Gross Horwitz Prize for Biology or Biochemistry is an annual prize awarded by Columbia University to a researcher or group of researchers that have made an outstanding contribution in basic research in the fields of biology or biochemistry....
 (1992).

His Nobel Prize winning studies with Drosophila
Drosophila melanogaster

Drosophila melanogaster is a two-winged insect that belongs to the Diptera, the Order of the Fly. The species is commonly known as the Drosophilidae or vinegar fly, and is one of the most commonly used model organisms in biology, including studies in genetics, physiology and Life history theory....
 founded the field of developmental genetics and laid the groundwork for our current understanding of the universal, evolutionarily conserved strategies controlling animal development. He is credited with development of the complementation test
Complementation (genetics)

In genetics, complementation refers to a relationship between two different strain of an organism which both have homozygous recessive mutations that produce the same phenotype ....
. His key publications in the fields of genetics
Genetics

Genetics , a discipline of biology, is the science of heredity and Genetic variation in living organisms. The fact that living things inherit traits from their parents has been used since prehistoric times to improve crop plants and animals through selective breeding....
, developmental biology
Developmental biology

Developmental biology is the study of the process by which organisms grow and develop. Modern developmental biology studies the genetic control of cell growth, cellular differentiation and "morphogenesis," which is the process that gives rise to biological tissues, organ s and anatomy....
, radiation
Radiation

In physics, radiation describes any process in which energy emitted by one body travels through a medium or through space, ultimately to be absorbed by another body....
 and cancer
Cancer

Cancer is a class of diseases in which a group of cell display uncontrolled growth , invasion , and sometimes metastasis . These three malignant properties of cancers differentiate them from benign tumors, which are self-limited, do not invade or metastasize....
 are presented in the book Genes, Development and Cancer, which was released in 2004.

See also

  • Homeotic gene
    Homeotic gene

    Hox genes are a group a related genes that specify the anterior-posterior axis and Segmentation of Animal organisms during early Embryo development....
  • Transvection (genetics)
    Transvection (genetics)

    Transvection is an epigenetic phenomenon that results from an interaction between an allele on one chromosome and the corresponding allele on the homologous chromosome....


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