All Topics  
Dorsal root ganglion

 

 
   Email Print
   Bookmark   Link
 

 

Dorsal root ganglion
 
 
  Topics Dorsal root ganglion Topic Home

In anatomy
Anatomy

Anatomy is a branch of biology that is the consideration of the body plan. It is a general term that includes human anatomy, animal anatomy and plant anatomy ....
 and neurology
Neurology

Neurology is a medical specialty dealing with disorders of the nervous system. Specifically, it deals with the diagnosis and treatment of all categories of disease involving the Central nervous system, Peripheral nervous system, and autonomic nervous systems, including their coverings, blood vessels, and...
, the dorsal root ganglion
Ganglion

In anatomy, a ganglion is a biological tissue.Cells found in a ganglion are called ganglion cells, though this term is also sometimes used to refer specifically to Retinal ganglion cells....
 (or spinal ganglion) is a nodule on a dorsal root
Dorsal root

In anatomy and neurology, the dorsal root is the afferent nervesomatosensory system root of a spinal nerve.At the distal end of the dorsal root is the dorsal root ganglion, which contains the neuron cell bodies of the nerve fibres conveyed by the root....
 that contains cell bodies of neuron
Neuron

Neurons are responsive cell in the nervous system that process and transmit information by electrochemical Signal . They are the core components of the brain, the vertebrate spinal cord, the invertebrate ventral nerve cord, and the peripheral nerves....
s in afferent
Afferent nerve

In the nervous system, afferent neurons , carry action potential from receptor s or sense organs toward the central nervous system. This term can also be used to describe relative connections between structures....
 spinal nerve
Spinal nerve

The term spinal nerve generally refers to the mixed spinal nerve, which is formed from the dorsal and ventral roots that come out of the spinal cord....
s.

axons of dorsal root ganglion neurons are known as afferents. In the peripheral nervous system
Peripheral nervous system

The peripheral nervous system resides or extends outside the central nervous system , which consists of the brain and spinal cord. The main function of the PNS is to connect the CNS to the limbs and organs....
, afferents refer to the axons that relay sensory information into the central nervous system
Central nervous system

The central nervous system is the part of the nervous system that functions to coordinate the activity of all parts of the bodies of multicellular organisms....
 and spinal cord
Spinal cord

The spinal cord is a long, thin, tubular bundle of neuron and glia that extends from the brain. The brain and spinal cord together make up the central nervous system....
. These neurons are of the pseudo-unipolar type, meaning they have an axon with two branches that act as a single axon, often referred to as a distal process and a proximal process.

Unlike the majority of neurons found in the central nervous system
Central nervous system

The central nervous system is the part of the nervous system that functions to coordinate the activity of all parts of the bodies of multicellular organisms....
, an action potential
Action potential

An action potential is a self-regenerating wave of electrochemical activity that allows nerve cells to carry a signal over a distance. It is the primary electrical signal generated by nerve cells, and arises from changes in the permeability of the nerve cell's axonal Cell membranes to specific ions....
 in dorsal root ganglion neuron may initiate in the distal process in the periphery, bypass the cell body, and continue to propagate along the proximal process until reaching the synaptic terminal in the dorsal horn of the spinal cord.

distal section of the axon may either be a bare nerve ending or encapsulated by a structure that helps relay specific information to nerve.






Discussion
Ask a question about 'Dorsal root ganglion'
Start a new discussion about 'Dorsal root ganglion'
Answer questions from other users
Full Discussion Forum



Encyclopedia


In anatomy
Anatomy

Anatomy is a branch of biology that is the consideration of the body plan. It is a general term that includes human anatomy, animal anatomy and plant anatomy ....
 and neurology
Neurology

Neurology is a medical specialty dealing with disorders of the nervous system. Specifically, it deals with the diagnosis and treatment of all categories of disease involving the Central nervous system, Peripheral nervous system, and autonomic nervous systems, including their coverings, blood vessels, and...
, the dorsal root ganglion
Ganglion

In anatomy, a ganglion is a biological tissue.Cells found in a ganglion are called ganglion cells, though this term is also sometimes used to refer specifically to Retinal ganglion cells....
 (or spinal ganglion) is a nodule on a dorsal root
Dorsal root

In anatomy and neurology, the dorsal root is the afferent nervesomatosensory system root of a spinal nerve.At the distal end of the dorsal root is the dorsal root ganglion, which contains the neuron cell bodies of the nerve fibres conveyed by the root....
 that contains cell bodies of neuron
Neuron

Neurons are responsive cell in the nervous system that process and transmit information by electrochemical Signal . They are the core components of the brain, the vertebrate spinal cord, the invertebrate ventral nerve cord, and the peripheral nerves....
s in afferent
Afferent nerve

In the nervous system, afferent neurons , carry action potential from receptor s or sense organs toward the central nervous system. This term can also be used to describe relative connections between structures....
 spinal nerve
Spinal nerve

The term spinal nerve generally refers to the mixed spinal nerve, which is formed from the dorsal and ventral roots that come out of the spinal cord....
s.

Unique unipolar structure

The axons of dorsal root ganglion neurons are known as afferents. In the peripheral nervous system
Peripheral nervous system

The peripheral nervous system resides or extends outside the central nervous system , which consists of the brain and spinal cord. The main function of the PNS is to connect the CNS to the limbs and organs....
, afferents refer to the axons that relay sensory information into the central nervous system
Central nervous system

The central nervous system is the part of the nervous system that functions to coordinate the activity of all parts of the bodies of multicellular organisms....
 and spinal cord
Spinal cord

The spinal cord is a long, thin, tubular bundle of neuron and glia that extends from the brain. The brain and spinal cord together make up the central nervous system....
. These neurons are of the pseudo-unipolar type, meaning they have an axon with two branches that act as a single axon, often referred to as a distal process and a proximal process.

Unlike the majority of neurons found in the central nervous system
Central nervous system

The central nervous system is the part of the nervous system that functions to coordinate the activity of all parts of the bodies of multicellular organisms....
, an action potential
Action potential

An action potential is a self-regenerating wave of electrochemical activity that allows nerve cells to carry a signal over a distance. It is the primary electrical signal generated by nerve cells, and arises from changes in the permeability of the nerve cell's axonal Cell membranes to specific ions....
 in dorsal root ganglion neuron may initiate in the distal process in the periphery, bypass the cell body, and continue to propagate along the proximal process until reaching the synaptic terminal in the dorsal horn of the spinal cord.

Distal section

The distal section of the axon may either be a bare nerve ending or encapsulated by a structure that helps relay specific information to nerve. For example, a Meissner's corpuscle
Meissner's corpuscle

Meissner's corpuscles are a type of mechanoreceptor. They are a type of nerve endings in the skin that are responsible for sensitivity to light touch....
 or Pacinian corpuscle
Pacinian corpuscle

Pacinian corpuscles are one of the four major types of mechanoreceptor. They are nerve endings in the skin, responsible for sensitivity to deep pressure touch and high frequency vibration....
 may encapsulate the nerve ending, rendering the distal process sensitive to mechanical stimulation, such as stroking or vibration, respectively.

Location

The dorsal root ganglia lie along the vertebral column by the spine.

Embryology

The dorsal root ganglia develops in the embryo from neural crest
Neural crest

The neural crest, a transient component of the ectoderm, is located in between the neural tube and the epidermis of an embryo during neural tube formation....
 cells.

Nociception

G protein-coupled receptor
G protein-coupled receptor

G protein-coupled receptors , also known as seven transmembrane domain receptors, 7TM receptors, heptahelical receptors, serpentine receptor, and G protein-linked receptors , comprise a large protein family of transmembrane receptors that sense molecules outside the Cell and activate inside signal transductio...
 on the DRG have been associated with nociception
Nociception

Nociception is defined as "the neural processes of encoding and processing noxious stimuli." It is the afferent activity produced in the peripheral and central nervous system by stimuli that have the potential to damage tissue....
.

See also

  • Ventral root
    Ventral root

    In anatomy and neurology, the ventral root is the efferent nerve motoneuron root of a spinal nerve.At its distal end, the ventral root joins with the dorsal root to form a mixed spinal nerve....


Additional images


External links

  • at Ohio State University
    Ohio State University

    The Ohio State University is a public university research university in the state of Ohio. It was founded in 1870 as a land-grant university and is currently the List of largest United States universities by enrollment in the United States....
  • at webanatomy.net
  • at uwlax.edu