Detox (House)
Encyclopedia
"Detox" is the eleventh episode of the first season of House
House (TV series)
House is an American television medical drama that debuted on the Fox network on November 16, 2004. The show's central character is Dr. Gregory House , an unconventional and misanthropic medical genius who heads a team of diagnosticians at the fictional Princeton-Plainsboro Teaching Hospital in...

, which premiered on the Fox
Fox Broadcasting Company
Fox Broadcasting Company, commonly referred to as Fox Network or simply Fox , is an American commercial broadcasting television network owned by Fox Entertainment Group, part of Rupert Murdoch's News Corporation. Launched on October 9, 1986, Fox was the highest-rated broadcast network in the...

 network on February 15, 2005. The episode marks the first of repeated storylines in which the condition Lupus
Systemic lupus erythematosus
Systemic lupus erythematosus , often abbreviated to SLE or lupus, is a systemic autoimmune disease that can affect any part of the body. As occurs in other autoimmune diseases, the immune system attacks the body's cells and tissue, resulting in inflammation and tissue damage...

 is suggested but ruled out.

Plot

Cuddy bets a month's clinic duty that House can't stay off of Vicodin
Vicodin
Hydrocodone/paracetamol is a combination of two analgesic products hydrocodone and paracetamol used to relieve moderate to severe pain...

 for a week while House is trying to find out why a teenage car crash victim named Keith (Nicholas D'Agosto
Nicholas D'Agosto
- Early life :D'Agosto was born in Omaha, Nebraska, the son of Deanna Rae and Alen D'Agosto, who own several Arby's in Omaha. His father is Italian and his mother is of Dutch and English descent. He was raised Catholic and selected Genesius of Rome, the patron saint of actors, as his confirmation...

) won't stop bleeding after three weeks. Keith has hemolytic anemia
Hemolytic anemia
Hemolytic anemia is a form of anemia due to hemolysis, the abnormal breakdown of red blood cells , either in the blood vessels or elsewhere in the human body . It has numerous possible causes, ranging from relatively harmless to life-threatening...

 combined with internal bleeding, an uncommon but very serious condition, especially in 16-year-olds.

Foreman and Chase run through a series of tests, while Cameron probes to learn about Keith's medical history. The tests reveal no new information. A blood clot in his left eye causes the team to look for an infection, which again yields nothing. Chase recommends removing some fluid from his eye to relieve the clot, which works, but the patient's liver damage leads the team to settle on a rare form of hepatitis.

Meanwhile, House is experiencing severe withdrawal to the extent that he breaks his own fingers to distract himself from his aching leg. He mocks the patient's condition, angering the father. House states that Lupus
Lupus erythematosus
Lupus erythematosus is a category for a collection of diseases with similar underlying problems with immunity . Symptoms of these diseases can affect many different body systems, including joints, skin, kidneys, blood cells, heart, and lungs...

 is the most likely cause, but directs them to test for Hepatitis E
Hepatitis E
Hepatitis E is a viral hepatitis caused by infection with a virus called hepatitis E virus . HEV is a positive-sense single-stranded RNA icosahedral virus with a 7.5 kilobase genome. HEV has a fecal-oral transmission route. It is one of five known hepatitis viruses: A, B, C, D, and E...

, which is untreatable, to eliminate it first, which requires lying to the father. Foreman suggests that House take Vicodin to prevent fatal errors. Cameron admits lying to the father, and that she believes that Keith has Lupus.

Before administering Solu-Medrol to test for Hepatitis E, Keith has hallucinations about his deceased cat. The father is still too angry to listen to explanations, especially when they find that Keith will need a liver transplant to survive. Still unconvinced of the Lupus diagnosis, House sends Foreman and Chase to dig up the family cat. House performs a necropsy on the cat, finding the cause of the cat's death as well as what's affecting Keith.

The final diagnosis is naphthalene
Naphthalene
Naphthalene is an organic compound with formula . It is a white crystalline solid with a characteristic odor that is detectable at concentrations as low as 0.08 ppm by mass. As an aromatic hydrocarbon, naphthalene's structure consists of a fused pair of benzene rings...

 poisoning, brought on by a swarm of termites living within the walls of Keith's bedroom, that House reveals as the surgery to replace his liver is about to occur. Though everyone is reluctant to trust House (the father punches him), the father reluctantly agrees to accept the diagnosis. Chase and Foreman open Keith's wall and find a large amount of termites. Keith gets better, House wins his bet with Cuddy (the bet actually thought up by Dr. Wilson), and admits he's an addict. He doesn't see it as a problem since the pills let him do his work and take away his pain.

Awards

Hugh Laurie
Hugh Laurie
James Hugh Calum Laurie, OBE , better known as Hugh Laurie , is an English actor, voice artist, comedian, writer, musician, recording artist, and director...

 submitted this episode for consideration of his work for the 57th Primetime Emmy Awards
57th Primetime Emmy Awards
The 57th Annual Primetime Emmy Awards were held on September 18, 2005, hosted by Ellen DeGeneres. The 2005 Primetime Emmy Awards show was broadcast on CBS....

 in 2005. This resulted in his first Emmy Award
Primetime Emmy Award
The Primetime Emmy Awards are awards presented by the Academy of Television Arts & Sciences in recognition of excellence in American primetime television programming...

 nomination for "Outstanding Lead Actor in a Drama Series
Primetime Emmy Award for Outstanding Lead Actor - Drama Series
This is a list of the Primetime Emmy Award for Outstanding Lead Actor in a Drama Series winners.-1950s:*1956: Robert Young as Jim Anderson - Father Knows Best*1957: Robert Young as Jim Anderson - Father Knows Best...

" for his role as Dr. Gregory House.

External links

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