Depleted uranium
Encyclopedia

Depleted uranium is uranium
Uranium
Uranium is a silvery-white metallic chemical element in the actinide series of the periodic table, with atomic number 92. It is assigned the chemical symbol U. A uranium atom has 92 protons and 92 electrons, of which 6 are valence electrons...

 with a lower content of the fissile isotope U-235
Uranium-235
- References :* .* DOE Fundamentals handbook: Nuclear Physics and Reactor theory , .* A piece of U-235 the size of a grain of rice can produce energy equal to that contained in three tons of coal or fourteen barrels of oil. -External links:* * * one of the earliest articles on U-235 for the...

 than natural uranium (natural uranium is about 99.27% uranium-238
Uranium-238
Uranium-238 is the most common isotope of uranium found in nature. It is not fissile, but is a fertile material: it can capture a slow neutron and after two beta decays become fissile plutonium-239...

 (U-238), 0.72% U-235
Uranium-235
- References :* .* DOE Fundamentals handbook: Nuclear Physics and Reactor theory , .* A piece of U-235 the size of a grain of rice can produce energy equal to that contained in three tons of coal or fourteen barrels of oil. -External links:* * * one of the earliest articles on U-235 for the...

, and 0.0055% U-234). Uses of DU take advantage of its very high density
Density
The mass density or density of a material is defined as its mass per unit volume. The symbol most often used for density is ρ . In some cases , density is also defined as its weight per unit volume; although, this quantity is more properly called specific weight...

 of 19.1 g/cm3 (68.4% denser than lead). Civilian uses include counterweights in aircraft, radiation shielding in medical radiation therapy
Radiation therapy
Radiation therapy , radiation oncology, or radiotherapy , sometimes abbreviated to XRT or DXT, is the medical use of ionizing radiation, generally as part of cancer treatment to control malignant cells.Radiation therapy is commonly applied to the cancerous tumor because of its ability to control...

 and industrial radiography
Radiography
Radiography is the use of X-rays to view a non-uniformly composed material such as the human body. By using the physical properties of the ray an image can be developed which displays areas of different density and composition....

 equipment, and containers used to transport radioactive materials. Military uses include defensive armor plating and armor-piercing
Armor-piercing shot and shell
An armor-piercing shell is a type of ammunition designed to penetrate armor. From the 1860s to 1950s, a major application of armor-piercing projectiles was to defeat the thick armor carried on many warships. From the 1920s onwards, armor-piercing weapons were required for anti-tank missions...

 projectiles.

Most depleted uranium arises as a byproduct of the production of enriched uranium
Enriched uranium
Enriched uranium is a kind of uranium in which the percent composition of uranium-235 has been increased through the process of isotope separation. Natural uranium is 99.284% 238U isotope, with 235U only constituting about 0.711% of its weight...

 for use in nuclear reactor
Nuclear reactor
A nuclear reactor is a device to initiate and control a sustained nuclear chain reaction. Most commonly they are used for generating electricity and for the propulsion of ships. Usually heat from nuclear fission is passed to a working fluid , which runs through turbines that power either ship's...

s and in the manufacture of nuclear weapon
Nuclear weapon
A nuclear weapon is an explosive device that derives its destructive force from nuclear reactions, either fission or a combination of fission and fusion. Both reactions release vast quantities of energy from relatively small amounts of matter. The first fission bomb test released the same amount...

s. Enrichment processes generate from the uranium feed a small fraction of uranium with a higher-than-natural concentration of lower-mass uranium isotopes (in particular U-235, which is the uranium isotope supporting the fission
Nuclear fission
In nuclear physics and nuclear chemistry, nuclear fission is a nuclear reaction in which the nucleus of an atom splits into smaller parts , often producing free neutrons and photons , and releasing a tremendous amount of energy...

 chain reaction
Chain reaction
A chain reaction is a sequence of reactions where a reactive product or by-product causes additional reactions to take place. In a chain reaction, positive feedback leads to a self-amplifying chain of events....

) with the bulk of the feed ending up as depleted uranium, in some cases with mass fractions of U-235 and U-234 less than a third of those in natural uranium. U-238 has a much longer halflife than the lighter isotopes, and DU therefore emits less alpha radiation than the same mass of natural uranium: the US Defense Department states DU used in US munitions has 60% the radioactivity of natural uranium.


Since the U-235 content of nuclear reactor fuel is reduced by fission, uranium recovered by nuclear reprocessing
Nuclear reprocessing
Nuclear reprocessing technology was developed to chemically separate and recover fissionable plutonium from irradiated nuclear fuel. Reprocessing serves multiple purposes, whose relative importance has changed over time. Originally reprocessing was used solely to extract plutonium for producing...

 from spent nuclear reactor fuel made from natural uranium will have a lower-than-natural U-235 concentration. Such ‘reactor-depleted’ material will have different isotopics from enrichment byproduct DU, and can be distinguished from it by the presence of U-236
Uranium-236
- See also :* Depleted uranium* Uranium market* Nuclear reprocessing* United States Enrichment Corporation* Nuclear fuel cycle* Nuclear power-External links:* *...

. Trace transuranics (another indicator of the use of reprocessed material) have been reported to be present in some US tank armour


The use of DU in munitions is controversial because of questions about potential long-term health effects. Normal functioning of the kidney
Kidney
The kidneys, organs with several functions, serve essential regulatory roles in most animals, including vertebrates and some invertebrates. They are essential in the urinary system and also serve homeostatic functions such as the regulation of electrolytes, maintenance of acid–base balance, and...

, brain
Human brain
The human brain has the same general structure as the brains of other mammals, but is over three times larger than the brain of a typical mammal with an equivalent body size. Estimates for the number of neurons in the human brain range from 80 to 120 billion...

, liver
Liver
The liver is a vital organ present in vertebrates and some other animals. It has a wide range of functions, including detoxification, protein synthesis, and production of biochemicals necessary for digestion...

, heart
Human heart
The human heart is a muscular organ that provides a continuous blood circulation through the cardiac cycle and is one of the most vital organs in the human body...

, and numerous other systems can be affected by uranium exposure, because uranium is a toxic metal
Toxic metal
Toxic metals are metals that form poisonous soluble compounds and have no biological role, i.e. are not essential minerals, or are in the wrong form. Often heavy metals are thought as synonymous, but lighter metals also have toxicity, such as beryllium, and not all heavy metals are particularly...

. It is weakly radioactive and remains so because of its long physical half-life
Half-life
Half-life, abbreviated t½, is the period of time it takes for the amount of a substance undergoing decay to decrease by half. The name was originally used to describe a characteristic of unstable atoms , but it may apply to any quantity which follows a set-rate decay.The original term, dating to...

 (4.468 billion years for uranium-238
Uranium-238
Uranium-238 is the most common isotope of uranium found in nature. It is not fissile, but is a fertile material: it can capture a slow neutron and after two beta decays become fissile plutonium-239...

, 700 million years for uranium-235
Uranium-235
- References :* .* DOE Fundamentals handbook: Nuclear Physics and Reactor theory , .* A piece of U-235 the size of a grain of rice can produce energy equal to that contained in three tons of coal or fourteen barrels of oil. -External links:* * * one of the earliest articles on U-235 for the...

). The biological half-life
Biological half-life
The biological half-life or elimination half-life of a substance is the time it takes for a substance to lose half of its pharmacologic, physiologic, or radiologic activity, as per the MeSH definition...

 (the average time it takes for the human body to eliminate half the amount in the body) for uranium is about 15 days. The aerosol or spallation frangible powder produced during impact and combustion of depleted uranium munitions can potentially contaminate wide areas around the impact sites leading to possible inhalation by human beings.

The actual acute and chronic toxicity of DU is also a point of medical controversy. Multiple studies using cultured cells and laboratory rodents suggest the possibility of leukemogenic
Leukemia
Leukemia or leukaemia is a type of cancer of the blood or bone marrow characterized by an abnormal increase of immature white blood cells called "blasts". Leukemia is a broad term covering a spectrum of diseases...

, gene
Gene
A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a type of protein or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains...

tic, reproductive, and neurological effects from chronic exposure.
A 2005 epidemiology
Epidemiology
Epidemiology is the study of health-event, health-characteristic, or health-determinant patterns in a population. It is the cornerstone method of public health research, and helps inform policy decisions and evidence-based medicine by identifying risk factors for disease and targets for preventive...

 review concluded: "In aggregate the human epidemiological evidence is consistent with increased risk of birth defects in offspring of persons exposed to DU." The World Health Organization
World Health Organization
The World Health Organization is a specialized agency of the United Nations that acts as a coordinating authority on international public health. Established on 7 April 1948, with headquarters in Geneva, Switzerland, the agency inherited the mandate and resources of its predecessor, the Health...

, the directing and coordinating authority for health within the United Nations which is responsible for setting health research norms and standards, providing technical support to countries and monitoring and assessing health trends, states that no risk of reproductive, developmental, or carcinogenic effects have been reported in humans due to DU exposure. This report has been criticized by Dr. Keith Baverstock for not including possible long term effects of DU on the human body.

History

Enriched uranium was first manufactured in the early 1940s when the United States
United States
The United States of America is a federal constitutional republic comprising fifty states and a federal district...

 began its nuclear weapons program. Later in the decade, Britain
United Kingdom
The United Kingdom of Great Britain and Northern IrelandIn the United Kingdom and Dependencies, other languages have been officially recognised as legitimate autochthonous languages under the European Charter for Regional or Minority Languages...

, France
France
The French Republic , The French Republic , The French Republic , (commonly known as France , is a unitary semi-presidential republic in Western Europe with several overseas territories and islands located on other continents and in the Indian, Pacific, and Atlantic oceans. Metropolitan France...

, and the Soviet Union
Soviet Union
The Soviet Union , officially the Union of Soviet Socialist Republics , was a constitutionally socialist state that existed in Eurasia between 1922 and 1991....

 began their nuclear weapon
Nuclear weapon
A nuclear weapon is an explosive device that derives its destructive force from nuclear reactions, either fission or a combination of fission and fusion. Both reactions release vast quantities of energy from relatively small amounts of matter. The first fission bomb test released the same amount...

s and nuclear power
Nuclear power
Nuclear power is the use of sustained nuclear fission to generate heat and electricity. Nuclear power plants provide about 6% of the world's energy and 13–14% of the world's electricity, with the U.S., France, and Japan together accounting for about 50% of nuclear generated electricity...

 programs. It was at this time that depleted uranium was first stored as an unusable waste product (uranium hexafluoride
Uranium hexafluoride
Uranium hexafluoride , referred to as "hex" in the nuclear industry, is a compound used in the uranium enrichment process that produces fuel for nuclear reactors and nuclear weapons. It forms solid grey crystals at standard temperature and pressure , is highly toxic, reacts violently with water...

). There was some hope that the enrichment process would be improved and fission
Nuclear fission
In nuclear physics and nuclear chemistry, nuclear fission is a nuclear reaction in which the nucleus of an atom splits into smaller parts , often producing free neutrons and photons , and releasing a tremendous amount of energy...

able isotope
Isotope
Isotopes are variants of atoms of a particular chemical element, which have differing numbers of neutrons. Atoms of a particular element by definition must contain the same number of protons but may have a distinct number of neutrons which differs from atom to atom, without changing the designation...

s of U-235 could, at some future date, be extracted from the depleted uranium. This re-enrichment recovery of the residual uranium-235 contained in the depleted uranium is no longer a matter of the future: it has been practiced for several years. Also, it is possible to design civilian power reactors with unenriched fuel, but only about 10% of reactors ever built utilize that technology, and both nuclear weapons production and naval reactors
Nuclear marine propulsion
Nuclear marine propulsion is propulsion of a ship by a nuclear reactor. Naval nuclear propulsion is propulsion that specifically refers to naval warships...

 require the concentrated isotope.

In the 1970s, the Pentagon
The Pentagon
The Pentagon is the headquarters of the United States Department of Defense, located in Arlington County, Virginia. As a symbol of the U.S. military, "the Pentagon" is often used metonymically to refer to the Department of Defense rather than the building itself.Designed by the American architect...

 reported that the Soviet military
Red Army
The Workers' and Peasants' Red Army started out as the Soviet Union's revolutionary communist combat groups during the Russian Civil War of 1918-1922. It grew into the national army of the Soviet Union. By the 1930s the Red Army was among the largest armies in history.The "Red Army" name refers to...

 had developed armor plating for Warsaw Pact
Warsaw Pact
The Warsaw Treaty Organization of Friendship, Cooperation, and Mutual Assistance , or more commonly referred to as the Warsaw Pact, was a mutual defense treaty subscribed to by eight communist states in Eastern Europe...

 tanks that NATO ammunition could not penetrate. The Pentagon began searching for material to make denser armor-piercing projectiles. After testing various metals, ordnance researchers settled on depleted uranium.

The US and NATO militaries used DU penetrator rounds in the 1991 Gulf War, the Bosnia war, bombing of Serbia
Operation Allied Force
The NATO bombing of Yugoslavia was NATO's military operation against the Federal Republic of Yugoslavia during the Kosovo War. The strikes lasted from March 24, 1999 to June 10, 1999...

, and the 2003 invasion of Iraq
2003 invasion of Iraq
The 2003 invasion of Iraq , was the start of the conflict known as the Iraq War, or Operation Iraqi Freedom, in which a combined force of troops from the United States, the United Kingdom, Australia and Poland invaded Iraq and toppled the regime of Saddam Hussein in 21 days of major combat operations...

.

While clearing a decades-old Hawaii
Hawaii
Hawaii is the newest of the 50 U.S. states , and is the only U.S. state made up entirely of islands. It is the northernmost island group in Polynesia, occupying most of an archipelago in the central Pacific Ocean, southwest of the continental United States, southeast of Japan, and northeast of...

 firing range in 2005, workers found depleted uranium fins from training rounds from the formerly classified Davy Crockett
Davy Crockett (nuclear device)
The M-28 or M-29 Davy Crockett Weapon System was a tactical nuclear recoilless gun for firing the M388 nuclear projectile that was deployed by the United States during the Cold War...

 recoilless gun tactical battlefield nuclear delivery system from the 1960-70s. These training rounds had been forgotten because they were used in a highly classified program and had been fired before DU had become an item of interest, more than 20 years before the Gulf War.

Production and availability

Natural uranium
Natural uranium
Natural uranium refers to refined uranium with the same isotopic ratio as found in nature. It contains 0.7 % uranium-235, 99.3 % uranium-238, and a trace of uranium-234 by weight. In terms of the amount of radioactivity, approximately 2.2 % comes from uranium-235, 48.6 % uranium-238, and 49.2 %...

 metal contains about 0.71% U-235
Uranium-235
- References :* .* DOE Fundamentals handbook: Nuclear Physics and Reactor theory , .* A piece of U-235 the size of a grain of rice can produce energy equal to that contained in three tons of coal or fourteen barrels of oil. -External links:* * * one of the earliest articles on U-235 for the...

, 99.28% U-238
Uranium-238
Uranium-238 is the most common isotope of uranium found in nature. It is not fissile, but is a fertile material: it can capture a slow neutron and after two beta decays become fissile plutonium-239...

, and about 0.0054% U-234. In order to produce enriched uranium
Enriched uranium
Enriched uranium is a kind of uranium in which the percent composition of uranium-235 has been increased through the process of isotope separation. Natural uranium is 99.284% 238U isotope, with 235U only constituting about 0.711% of its weight...

, the process of isotope separation
Isotope separation
Isotope separation is the process of concentrating specific isotopes of a chemical element by removing other isotopes, for example separating natural uranium into enriched uranium and depleted uranium. This is a crucial process in the manufacture of uranium fuel for nuclear power stations, and is...

 removes a substantial portion of the U-235 for use in nuclear power, weapons, or other uses. The remainder, depleted uranium, contains only 0.2% to 0.4% U-235. Because natural uranium begins with such a low percentage of U-235, enrichment produces large quantities of depleted uranium. For example, producing 1 kg of 5% enriched uranium requires 11.8 kg of natural uranium, and leaves about 10.8 kg of depleted uranium with only 0.3% U-235 remaining.

The Nuclear Regulatory Commission
Nuclear Regulatory Commission
The Nuclear Regulatory Commission is an independent agency of the United States government that was established by the Energy Reorganization Act of 1974 from the United States Atomic Energy Commission, and was first opened January 19, 1975...

 (NRC) defines depleted uranium as uranium with a percentage of the 235U isotope that is less than 0.711% by weight (see 10 CFR 40.4). The military specifications designate that the DU used by the U.S. Department of Defense (DoD) contain less than 0.3% 235U (AEPI, 1995). In actuality, DoD uses only DU that contains approximately 0.2% 235U (AEPI, 1995).

Uranium hexafluoride

About 95% of the depleted uranium produced is stored as uranium hexafluoride
Uranium hexafluoride
Uranium hexafluoride , referred to as "hex" in the nuclear industry, is a compound used in the uranium enrichment process that produces fuel for nuclear reactors and nuclear weapons. It forms solid grey crystals at standard temperature and pressure , is highly toxic, reacts violently with water...

, a crystalline solid, (D)UF6, in steel cylinders in open air storage yards close to enrichment plants. Each cylinder holds up to 12.7 tonnes (or 14 short tons) of UF6. In the U.S. 560,000 tonnes of depleted UF6 had accumulated by 1993. In 2008, 686,500 tonnes in 57,122 storage cylinders were located near Portsmouth, Ohio
Portsmouth, Ohio
Portsmouth is a city in the U.S. state of Ohio and the county seat of Scioto County. The municipality is located on the northern banks of the Ohio River and east of the Scioto River in Southern Ohio. The population was 20,226 at the 2010 census.-Foundation:...

 and Paducah, Kentucky
Paducah, Kentucky
Paducah is the largest city in Kentucky's Jackson Purchase Region and the county seat of McCracken County, Kentucky, United States. It is located at the confluence of the Tennessee River and the Ohio River, halfway between the metropolitan areas of St. Louis, Missouri, to the west and Nashville,...

.

The storage of DUF6 presents environmental, health, and safety risks because of its chemical instability. When UF6 is exposed to water vapor in the air, it reacts with the moisture to produce UO2F2 (uranyl fluoride
Uranyl fluoride
Uranyl fluoride , a compound of uranium, is an intermediate in the conversion of uranium hexafluoride UF6 to an uranium oxide or metal form and is a direct product of the reaction of UF6 with moisture in the air. It is very soluble in water. Uranyl fluoride also is hygroscopic and changes in color...

), a solid, and HF (hydrogen fluoride
Hydrofluoric acid
Hydrofluoric acid is a solution of hydrogen fluoride in water. It is a valued source of fluorine and is the precursor to numerous pharmaceuticals such as fluoxetine and diverse materials such as PTFE ....

), a gas, both of which are highly soluble and toxic. The uranyl fluoride solid acts to plug the leak, limiting further escape of depleted UF6. Release of the hydrogen fluoride gas to the atmosphere is also slowed by the plug formation. Storage cylinders must be regularly inspected for signs of corrosion and leaks and are repainted and repaired as necessary. The estimated lifetime of the steel cylinders is measured in decades.

A tenfold jump in uranium prices has transformed approximately one-third of the U.S. depleted uranium inventory into an asset worth $7.6 billion, assuming DOE re-enriches the tails. This estimate is based on February 2008 market price for uranium and enrichment services, and DOE's access to sufficient uranium enrichment capacity.

There have been several accidents involving uranium hexafluoride in the United States, including one in which 31 workers were exposed to a cloud of UF6 and its reaction products and a man died after inhaling some of the resulting gas. Though some of the more highly exposed workers showed evidence of short-term kidney
Kidney
The kidneys, organs with several functions, serve essential regulatory roles in most animals, including vertebrates and some invertebrates. They are essential in the urinary system and also serve homeostatic functions such as the regulation of electrolytes, maintenance of acid–base balance, and...

 damage (e.g., protein in the urine
Proteinuria
Proteinuria means the presence of anexcess of serum proteins in the urine. The protein in the urine often causes the urine to become foamy, although foamy urine may also be caused by bilirubin in the urine , retrograde ejaculation, pneumaturia due to a fistula, or drugs such as pyridium.- Causes...

), none of these workers had lasting kidney toxicity from the uranium exposure. The U.S. government has been converting DUF6 to solid uranium oxides for use or disposal. Such disposal of the entire DUF6 inventory could cost anywhere from $15 million to $450 million.
World depleted uranium inventory
{| class="wikitable"

|-
! Country
! Organization
! Estimated DU stocks
(tonnes)
! Reported
|-
|| United States
||DOE
United States Department of Energy
The United States Department of Energy is a Cabinet-level department of the United States government concerned with the United States' policies regarding energy and safety in handling nuclear material...


|align=right| 480,000        
|align=center| 2002
|-
|| Russia
||FAEA
|align=right| 460,000        
|align=center| 1996
|-
|| Early Modern France
||Areva NC
Areva NC
Areva NC, formerly Cogema is a French company, created in 1976 from the production division of the French government's CEA It is an industrial group active in all stages of the uranium fuel cycle, including uranium mining, conversion, enrichment, spent fuel reprocessing, and recycling...


|align=right| 190,000        
|align=center| 2001
|-
|| United Kingdom
||BNFL
BNFL
British Nuclear Fuels Limited was a nuclear energy and fuels company owned by the UK Government. It was a former manufacturer and transporter of nuclear fuel , ran reactors, generated and sold electricity, reprocessed and managed spent fuel , and decommissioned nuclear plants and other similar...


|align=right| 30,000        
|align=center| 2001
|-
|| Germany
 Netherlands
 United Kingdom
||URENCO
|align=right| 16,000        
|align=center| 1999
|-
|| Japan
||JNFL
|align=right| 10,000        
|align=center| 2001
|-
|| Mainland China
||CNNC
|align=right| 2,000        
|align=center| 2000
|-
|| South Korea
||KAERI
KAERI
The Korea Atomic Energy Research Institute in Daejeon, South Korea was established in 1959 as the sole professional research-oriented institute for nuclear power in South Korea, and has rapidly built a reputation for research and development in various fields...


|align=right| 200        
|align=center| 2002
|-
|| South Africa
||NECSA
NECSA
The South African Nuclear Energy Corporation was established as a public company by the Republic of South Africa Nuclear Energy Act in 1999 and is wholly owned by the State...


|align=right| 73        
|align=center| 2001
|-
|| Singapore
||DSO National Laboratories
|align=right| 60        
|align=center| 2007
|-
||TOTAL
||
|align=right| 1,188,273        
|align=center| 2008
|}
Source: WISE Uranium Project

Military applications

Depleted uranium is very dense; at 19050 kg/m³, it is 1.67 times as dense as lead
Lead
Lead is a main-group element in the carbon group with the symbol Pb and atomic number 82. Lead is a soft, malleable poor metal. It is also counted as one of the heavy metals. Metallic lead has a bluish-white color after being freshly cut, but it soon tarnishes to a dull grayish color when exposed...

, only slightly less dense than tungsten
Tungsten
Tungsten , also known as wolfram , is a chemical element with the chemical symbol W and atomic number 74.A hard, rare metal under standard conditions when uncombined, tungsten is found naturally on Earth only in chemical compounds. It was identified as a new element in 1781, and first isolated as...

 and gold
Gold
Gold is a chemical element with the symbol Au and an atomic number of 79. Gold is a dense, soft, shiny, malleable and ductile metal. Pure gold has a bright yellow color and luster traditionally considered attractive, which it maintains without oxidizing in air or water. Chemically, gold is a...

, and 84% as dense as osmium
Osmium
Osmium is a chemical element with the symbol Os and atomic number 76. Osmium is a hard, brittle, blue-gray or blue-blacktransition metal in the platinum family, and is the densest natural element. Osmium is twice as dense as lead. The density of osmium is , slightly greater than that of iridium,...

 or iridium
Iridium
Iridium is the chemical element with atomic number 77, and is represented by the symbol Ir. A very hard, brittle, silvery-white transition metal of the platinum family, iridium is the second-densest element and is the most corrosion-resistant metal, even at temperatures as high as 2000 °C...

, which are the densest known substances under standard (i.e., Earth-surface) pressures. Thus a given mass of it has a smaller diameter than an equivalent lead projectile, with less aerodynamic drag
External ballistics
External ballistics is the part of the science of ballistics that deals with the behaviour of a non-powered projectile in flight. External ballistics is frequently associated with firearms, and deals with the behaviour of the bullet after it exits the barrel and before it hits the target.-Forces...

 and deeper penetration
Terminal ballistics
Terminal ballistics, a sub-field of ballistics, is the study of the behavior of a projectile when it hits its target. It is often referred to as stopping power when dealing with human or other living targets. Terminal ballistics is relevant both for small caliber projectiles as well as for large...

 due to a higher pressure at point of impact. DU projectile ordnance is often incendiary
Incendiary device
Incendiary weapons, incendiary devices or incendiary bombs are bombs designed to start fires or destroy sensitive equipment using materials such as napalm, thermite, chlorine trifluoride, or white phosphorus....

 because of its pyrophoric property.

Armor plate

Because of its high density, depleted uranium can also be used in tank armor, sandwiched between sheets of steel armor plate. For instance, some late-production M1A1HA and M1A2 Abrams
M1 Abrams
The M1 Abrams is a third-generation main battle tank produced in the United States. It is named after General Creighton Abrams, former Army Chief of Staff and Commander of US military forces in Vietnam from 1968 to 1972. The M1 is a well armed, heavily armored, and highly mobile tank designed for...

 tanks built after 1998 have DU reinforcement as part of the armor plating in the front of the hull and the front of the turret, and there is a program to upgrade the rest (see Chobham armor).

Nuclear weapons

Depleted uranium is used as a tamper in fission bombs.

Ammunition

Most military use of depleted uranium has been as 30 mm caliber
30 mm caliber
30 mm caliber ammunition is usually used in autocannon. Such ammunition includes NATO standard 30 × 173 mm and 30 × 113 mm and Soviet 30 × 165 mm ammunition widely used around the world....

 ordnance, primarily the 30 mm PGU-14/B armour-piercing incendiary
Incendiary device
Incendiary weapons, incendiary devices or incendiary bombs are bombs designed to start fires or destroy sensitive equipment using materials such as napalm, thermite, chlorine trifluoride, or white phosphorus....

 round from the GAU-8 Avenger
GAU-8 Avenger
The General Electric GAU-8/A Avenger is a 30 mm, hydraulically-driven seven-barrel Gatling-type rotary cannon that is mounted on the United States Air Force's Fairchild Republic A-10 Thunderbolt II. It is among the largest, heaviest and most powerful aircraft cannons in the United States military...

 cannon of the A-10 Thunderbolt II
A-10 Thunderbolt II
The Fairchild Republic A-10 Thunderbolt II is an American single-seat, twin-engine, straight-wing jet aircraft developed by Fairchild-Republic in the early 1970s. The A-10 was designed for a United States Air Force requirement to provide close air support for ground forces by attacking tanks,...

 used by the United States Air Force
United States Air Force
The United States Air Force is the aerial warfare service branch of the United States Armed Forces and one of the American uniformed services. Initially part of the United States Army, the USAF was formed as a separate branch of the military on September 18, 1947 under the National Security Act of...

. 25 mm DU rounds have been used in the M242 gun mounted on the U.S. Army's Bradley Fighting Vehicle
M2 Bradley
The Bradley Fighting Vehicle is an American fighting vehicle platform manufactured by BAE Systems Land and Armaments, formerly United Defense.As with other infantry fighting vehicles, the Bradley is designed to transport infantry with armor protection while providing covering fire to suppress enemy...

 and Marine Corp'sLAV-25.

The United States Marine Corps
United States Marine Corps
The United States Marine Corps is a branch of the United States Armed Forces responsible for providing power projection from the sea, using the mobility of the United States Navy to deliver combined-arms task forces rapidly. It is one of seven uniformed services of the United States...

 uses DU in the 25 mm PGU-20 round fired by the GAU-12 Equalizer
GAU-12 Equalizer
The General Dynamics GAU-12/U Equalizer is a five-barrel 25 mm Gatling gun-style rotary cannon. The GAU-12/U is used by the United States, Italy and Spain, which mount the weapon in their fighter jets such as the AV-8B Harrier II, airborne gunships such as the Lockheed AC-130, and land-based...

 cannon of the AV-8B Harrier, and also in the 20 mm M197 gun mounted on AH-1 Cobra
AH-1 Cobra
The Bell AH-1 Cobra is a two-bladed, single engine attack helicopter manufactured by Bell Helicopter. It shares a common engine, transmission and rotor system with the older UH-1 Iroquois...

 helicopter gunships. The United States Navy
United States Navy
The United States Navy is the naval warfare service branch of the United States Armed Forces and one of the seven uniformed services of the United States. The U.S. Navy is the largest in the world; its battle fleet tonnage is greater than that of the next 13 largest navies combined. The U.S...

's Phalanx CIWS
Phalanx CIWS
The Phalanx CIWS is an anti-ship missile defense system. It is a close-in weapon system and was designed and manufactured by the General Dynamics Corporation, Pomona Division...

's M61 Vulcan
M61 Vulcan
The M61 Vulcan is a hydraulically or pneumatically driven, six-barreled, air-cooled, electrically fired Gatling-style rotary cannon which fires 20 mm rounds at an extremely high rate. The M61 and its derivatives have been the principal cannon armament of United States military fixed-wing aircraft...

 Gatling gun
Gatling gun
The Gatling gun is one of the best known early rapid-fire weapons and a forerunner of the modern machine gun. It is well known for its use by the Union forces during the American Civil War in the 1860s, which was the first time it was employed in combat...

 used 20 mm armor-piercing penetrator rounds with discarding plastic
Plastic
A plastic material is any of a wide range of synthetic or semi-synthetic organic solids used in the manufacture of industrial products. Plastics are typically polymers of high molecular mass, and may contain other substances to improve performance and/or reduce production costs...

 sabot
Sabot
A sabot is a device used in a firearm or cannon to fire a projectile, such as a bullet, that is smaller than the bore diameter, or which must be held in a precise position. The term is also applied to a battery stub case, a device used similarly to make a small electrical battery usable in a...

s which were made using depleted uranium, later changed to tungsten
Tungsten
Tungsten , also known as wolfram , is a chemical element with the chemical symbol W and atomic number 74.A hard, rare metal under standard conditions when uncombined, tungsten is found naturally on Earth only in chemical compounds. It was identified as a new element in 1781, and first isolated as...

.

Another use of depleted uranium is in kinetic energy penetrator
Kinetic energy penetrator
A kinetic energy penetrator is a type of ammunition which, like a bullet, does not contain explosives and uses kinetic energy to penetrate the target....

s anti-armor rounds, such as the 120 mm sabot rounds fired from the M1A1 and M1A2 Abrams. Kinetic energy penetrator rounds consist of a long, relatively thin penetrator surrounded by discarding sabot
Sabot
A sabot is a device used in a firearm or cannon to fire a projectile, such as a bullet, that is smaller than the bore diameter, or which must be held in a precise position. The term is also applied to a battery stub case, a device used similarly to make a small electrical battery usable in a...

. Staballoys are metal alloys of depleted uranium with a very small proportion of other metals, usually titanium
Titanium
Titanium is a chemical element with the symbol Ti and atomic number 22. It has a low density and is a strong, lustrous, corrosion-resistant transition metal with a silver color....

 or molybdenum
Molybdenum
Molybdenum , is a Group 6 chemical element with the symbol Mo and atomic number 42. The name is from Neo-Latin Molybdaenum, from Ancient Greek , meaning lead, itself proposed as a loanword from Anatolian Luvian and Lydian languages, since its ores were confused with lead ores...

. One formulation has a composition of 99.25% by mass of depleted uranium and 0.75% by mass of titanium
Titanium
Titanium is a chemical element with the symbol Ti and atomic number 22. It has a low density and is a strong, lustrous, corrosion-resistant transition metal with a silver color....

. Staballoys are approximately 1.67 times as dense as lead and are designed for use in kinetic energy penetrator
Kinetic energy penetrator
A kinetic energy penetrator is a type of ammunition which, like a bullet, does not contain explosives and uses kinetic energy to penetrate the target....

 armor-piercing ammunition. The US Army
United States Army
The United States Army is the main branch of the United States Armed Forces responsible for land-based military operations. It is the largest and oldest established branch of the U.S. military, and is one of seven U.S. uniformed services...

 uses DU in an alloy with around 3.5% titanium.

According to recent research, at least some of the most promising tungsten alloys that have been considered as replacement for depleted uranium in penetrator ammunitions, such as tungsten-cobalt
Cobalt
Cobalt is a chemical element with symbol Co and atomic number 27. It is found naturally only in chemically combined form. The free element, produced by reductive smelting, is a hard, lustrous, silver-gray metal....

 or tungsten-nickel
Nickel
Nickel is a chemical element with the chemical symbol Ni and atomic number 28. It is a silvery-white lustrous metal with a slight golden tinge. Nickel belongs to the transition metals and is hard and ductile...

-cobalt alloys, also possess extreme carcinogen
Carcinogen
A carcinogen is any substance, radionuclide, or radiation that is an agent directly involved in causing cancer. This may be due to the ability to damage the genome or to the disruption of cellular metabolic processes...

ic properties, which by far exceed those (confirmed or suspected) of depleted uranium itself: 100% of rat
Rat
Rats are various medium-sized, long-tailed rodents of the superfamily Muroidea. "True rats" are members of the genus Rattus, the most important of which to humans are the black rat, Rattus rattus, and the brown rat, Rattus norvegicus...

s implanted with a pellet of such alloys developed lethal rhabdomyosarcoma
Rhabdomyosarcoma
A rhabdomyosarcoma is a type of cancer, specifically a sarcoma , in which the cancer cells are thought to arise from skeletal muscle progenitors. It can also be found attached to muscle tissue, wrapped around intestines, or in any anatomic location...

 within a few weeks.

Depleted uranium is favored for the penetrator because it is self-sharpening and pyrophoric. On impact with a hard target, such as an armored vehicle, the nose of the rod fractures in such a way that it remains sharp. The impact and subsequent release of heat energy causes it to disintegrate to dust and burn when it reaches air because of its pyrophoric properties. When a DU penetrator reaches the interior of an armored vehicle, it catches fire, often igniting ammunition and fuel, killing the crew, and possibly causing the vehicle to explode. DU is used by the U.S. Army in 120 mm or 105 mm cannons employed on the M1 Abrams
M1 Abrams
The M1 Abrams is a third-generation main battle tank produced in the United States. It is named after General Creighton Abrams, former Army Chief of Staff and Commander of US military forces in Vietnam from 1968 to 1972. The M1 is a well armed, heavily armored, and highly mobile tank designed for...

 tank
Tank
A tank is a tracked, armoured fighting vehicle designed for front-line combat which combines operational mobility, tactical offensive, and defensive capabilities...

. The Russian military has used DU ammunition in tank
Tank
A tank is a tracked, armoured fighting vehicle designed for front-line combat which combines operational mobility, tactical offensive, and defensive capabilities...

 main gun ammunition since the late 1970s, mostly for the 115 mm guns in the T-62
T-62
The T-62 is a Soviet main battle tank, a further development of the T-55. Its 115 mm gun was the first smoothbore tank gun in use.The T-62 was produced between 1961 and 1975. It became a standard tank in the Soviet arsenal, partly replacing the T-55, although that tank continued to be...

 tank and the 125 mm guns in the T-64
T-64
The T-64 is a Soviet main battle tank, introduced in the early 1960s. It was used solely by the Soviet Army in its front-line divisions and was a more advanced counterpart to the T-62...

, T-72
T-72
The T-72 is a Soviet-designed main battle tank that entered production in 1970. It is developed directly from Obyekt-172, and shares parallel features with the T-64A...

, T-80
T-80
The T-80 is a main battle tank designed and manufactured in the former Soviet Union. A development of the T-64, it entered service in 1976 and was the first production tank to be equipped with a gas turbine engine for main propulsion.the Swedish Stridsvagn 103 of 1971 used a gas turbine alongside...

, and T-90
T-90
The T-90 is a Russian third-generation main battle tank that is a modernisation of the T-72 . It is currently the most modern tank in service with the Russian Ground Forces and Naval Infantry...

 tanks.

The DU content in various ammunition is 180 g in 20 mm projectiles, 200 g in 25 mm ones, 280 g in 30 mm, 3.5 kg in 105 mm, and 4.5 kg in 120 mm penetrators. DU was used during the mid-1990s in the U.S. to make grenades
Hand grenade
A hand grenade is any small bomb that can be thrown by hand. Hand grenades are classified into three categories, explosive grenades, chemical and gas grenades. Explosive grenades are the most commonly used in modern warfare, and are designed to detonate after impact or after a set amount of time...

, cluster bomb
Cluster bomb
A cluster munition is a form of air-dropped or ground-launched explosive weapon that releases or ejects smaller sub-munitions. Commonly, this is a cluster bomb that ejects explosive bomblets that are designed to kill enemy personnel and destroy vehicles...

s, and mines
Land mine
A land mine is usually a weight-triggered explosive device which is intended to damage a target—either human or inanimate—by means of a blast and/or fragment impact....

, but those applications have been discontinued, according to Alliant Techsystems
Alliant Techsystems
Alliant Techsystems Inc., most commonly known by its ticker symbol, ', is one of the largest aerospace and defense companies in the United States with more than 18,000 employees in 22 states, Puerto Rico and internationally, and 2010 revenues in excess of an estimated...

. The US Navy used DU in its 20 mm Phalanx CIWS
Phalanx CIWS
The Phalanx CIWS is an anti-ship missile defense system. It is a close-in weapon system and was designed and manufactured by the General Dynamics Corporation, Pomona Division...

 guns, but switched in the late 1990s to armor-piercing tungsten.

Depleted uranium is also suspected, by Doug Rokke, to be used in a variety of U.S. manufactured bombs and missiles, in particular bunker buster
Bunker buster
A bunker buster is a bomb designed to penetrate hardened targets or targets buried deep underground.-Germany:Röchling shells were bunker-busting artillery shells, developed by German engineer August Cönders, based on the theory of increasing sectional density to improve penetration.They were tested...

 or high penetrating ordinance such as versions of the GBU-28
GBU-28
The Guided Bomb Unit 28 is a 5,000 pound laser-guided "bunker busting" bomb nicknamed "Deep Throat" produced originally by the Watervliet Arsenal, Watervliet, New York. It was designed, manufactured, and deployed in less than three weeks due to an urgent need during Operation Desert Storm to...

 fitted with the BLU-113 advanced unitary penetrator, and the BLU-116
BLU-116
The BLU-116 is a United States Air Force bomb, designed as an enhanced Bunker buster penetration weapon, designed to penetrate deep into rock or concrete and destroy hard targets....

 where increased warhead density allows for increased penetration. If this is the case, very large quantities of depleted uranium may be contained within each bomb or missile, which would be largely vaporized on impact- the widespread use of these weapons would thus constitute a major source of depleted uranium contamination. Depleted uranium has also been utilized in High explosive anti-tank warheads (HEAT), one example is the Russian 3BK-21B 125mm HEAT tank round.

It is thought that between 17 and 20 countries have weapons incorporating depleted uranium in their arsenals. They include the U.S., the UK
United Kingdom
The United Kingdom of Great Britain and Northern IrelandIn the United Kingdom and Dependencies, other languages have been officially recognised as legitimate autochthonous languages under the European Charter for Regional or Minority Languages...

, France
France
The French Republic , The French Republic , The French Republic , (commonly known as France , is a unitary semi-presidential republic in Western Europe with several overseas territories and islands located on other continents and in the Indian, Pacific, and Atlantic oceans. Metropolitan France...

, Russia
Russia
Russia or , officially known as both Russia and the Russian Federation , is a country in northern Eurasia. It is a federal semi-presidential republic, comprising 83 federal subjects...

, China
People's Republic of China
China , officially the People's Republic of China , is the most populous country in the world, with over 1.3 billion citizens. Located in East Asia, the country covers approximately 9.6 million square kilometres...

, India
India
India , officially the Republic of India , is a country in South Asia. It is the seventh-largest country by geographical area, the second-most populous country with over 1.2 billion people, and the most populous democracy in the world...

, Turkey
Turkey
Turkey , known officially as the Republic of Turkey , is a Eurasian country located in Western Asia and in East Thrace in Southeastern Europe...

, Saudi Arabia
Saudi Arabia
The Kingdom of Saudi Arabia , commonly known in British English as Saudi Arabia and in Arabic as as-Sa‘ūdiyyah , is the largest state in Western Asia by land area, constituting the bulk of the Arabian Peninsula, and the second-largest in the Arab World...

, Israel
Israel
The State of Israel is a parliamentary republic located in the Middle East, along the eastern shore of the Mediterranean Sea...

, Bahrain
Bahrain
' , officially the Kingdom of Bahrain , is a small island state near the western shores of the Persian Gulf. It is ruled by the Al Khalifa royal family. The population in 2010 stood at 1,214,705, including 235,108 non-nationals. Formerly an emirate, Bahrain was declared a kingdom in 2002.Bahrain is...

, Egypt
Egypt
Egypt , officially the Arab Republic of Egypt, Arabic: , is a country mainly in North Africa, with the Sinai Peninsula forming a land bridge in Southwest Asia. Egypt is thus a transcontinental country, and a major power in Africa, the Mediterranean Basin, the Middle East and the Muslim world...

, Kuwait
Kuwait
The State of Kuwait is a sovereign Arab state situated in the north-east of the Arabian Peninsula in Western Asia. It is bordered by Saudi Arabia to the south at Khafji, and Iraq to the north at Basra. It lies on the north-western shore of the Persian Gulf. The name Kuwait is derived from the...

, Pakistan
Pakistan
Pakistan , officially the Islamic Republic of Pakistan is a sovereign state in South Asia. It has a coastline along the Arabian Sea and the Gulf of Oman in the south and is bordered by Afghanistan and Iran in the west, India in the east and China in the far northeast. In the north, Tajikistan...

, Thailand
Thailand
Thailand , officially the Kingdom of Thailand , formerly known as Siam , is a country located at the centre of the Indochina peninsula and Southeast Asia. It is bordered to the north by Burma and Laos, to the east by Laos and Cambodia, to the south by the Gulf of Thailand and Malaysia, and to the...

, Iraq
Iraq
Iraq ; officially the Republic of Iraq is a country in Western Asia spanning most of the northwestern end of the Zagros mountain range, the eastern part of the Syrian Desert and the northern part of the Arabian Desert....

 and Taiwan
Republic of China
The Republic of China , commonly known as Taiwan , is a unitary sovereign state located in East Asia. Originally based in mainland China, the Republic of China currently governs the island of Taiwan , which forms over 99% of its current territory, as well as Penghu, Kinmen, Matsu and other minor...

. DU ammunition is manufactured in 18 countries. Only the US and the UK have acknowledged using DU weapons.

In a three week period of conflict in Iraq during 2003 it was estimated over 1000 tons of depleted uranium munitions were used.

Legal status in weapons

In 1996 the International Court of Justice
International Court of Justice
The International Court of Justice is the primary judicial organ of the United Nations. It is based in the Peace Palace in The Hague, Netherlands...

 (ICJ) gave an advisory opinion on the "legality of the threat or use of nuclear weapons". This made it clear, in paragraphs 54, 55 and 56, that international law
International law
Public international law concerns the structure and conduct of sovereign states; analogous entities, such as the Holy See; and intergovernmental organizations. To a lesser degree, international law also may affect multinational corporations and individuals, an impact increasingly evolving beyond...

 on poisonous weapons—the Second Hague Declaration of 29 July 1899, Hague Convention IV of 18 October 1907 and the Geneva Protocol of 17 June 1925—did not cover nuclear weapons, because their prime or exclusive use was not to poison or asphyxiate. This ICJ opinion was about nuclear weapons, but the sentence "The terms have been understood, in the practice of States, in their ordinary sense as covering weapons whose prime, or even exclusive, effect is to poison or asphyxiate," also removes depleted uranium weaponry from coverage by the same treaties as their primary use is not to poison or asphyxiate, but to destroy materiel
Materiel
Materiel is a term used in English to refer to the equipment and supplies in military and commercial supply chain management....

 and kill soldiers through kinetic energy
Kinetic energy
The kinetic energy of an object is the energy which it possesses due to its motion.It is defined as the work needed to accelerate a body of a given mass from rest to its stated velocity. Having gained this energy during its acceleration, the body maintains this kinetic energy unless its speed changes...

.

The Sub-Commission on Prevention of Discrimination and Protection of Minorities of the United Nations Human Rights Commission, passed two motions — the first in 1996 and the second in 1997. They listed weapons of mass destruction
Weapons of mass destruction
A weapon of mass destruction is a weapon that can kill and bring significant harm to a large number of humans and/or cause great damage to man-made structures , natural structures , or the biosphere in general...

, or weapons with indiscriminate effect, or of a nature to cause superfluous injury or unnecessary suffering and urged all states to curb the production and the spread of such weapons. Included in the list was weaponry containing depleted uranium. The committee authorized a working paper, in the context of human rights
Human rights
Human rights are "commonly understood as inalienable fundamental rights to which a person is inherently entitled simply because she or he is a human being." Human rights are thus conceived as universal and egalitarian . These rights may exist as natural rights or as legal rights, in both national...

 and humanitarian norms, of the weapons.

The requested UN working paper was delivered in 2002 by Y.K.J. Yeung Sik Yuen in accordance with Sub-Commission on the Promotion and Protection of Human Rights
Sub-Commission on the Promotion and Protection of Human Rights
The Sub-Commission on the Promotion and Protection of Human Rights was a think tank of the United Nations Commission on Human Rights...

 resolution 2001/36. He argues that the use of DU in weapons, along with the other weapons listed by the Sub‑Commission, may breach one or more of the following treaties: the Universal Declaration of Human Rights, the Charter of the United Nations, the Genocide Convention
Convention on the Prevention and Punishment of the Crime of Genocide
The Convention on the Prevention and Punishment of the Crime of Genocide was adopted by the United Nations General Assembly on 9 December 1948 as General Assembly Resolution 260. The Convention entered into force on 12 January 1951. It defines genocide in legal terms, and is the culmination of...

, the United Nations Convention Against Torture
United Nations Convention Against Torture
The United Nations Convention against Torture and Other Cruel, Inhuman or Degrading Treatment or Punishment is an international human rights instrument, under the review of the United Nations, that aims to prevent torture around the world....

, the Geneva Conventions
Geneva Conventions
The Geneva Conventions comprise four treaties, and three additional protocols, that establish the standards of international law for the humanitarian treatment of the victims of war...

 including Protocol I
Protocol I
Protocol I is a 1977 amendment protocol to the Geneva Conventions relating to the protection of victims of international armed conflicts. It reaffirms the international laws of the original Geneva Conventions of 1949, but adds clarifications and new provisions to accommodate developments in modern...

, the Convention on Conventional Weapons of 1980, and the Chemical Weapons Convention
Chemical Weapons Convention
The Chemical Weapons Convention is an arms control agreement which outlaws the production, stockpiling and use of chemical weapons. Its full name is the Convention on the Prohibition of the Development, Production, Stockpiling and Use of Chemical Weapons and on their Destruction...

. Yeung Sik Yuen writes in Paragraph 133 under the title "Legal compliance of weapons containing DU as a new weapon":
In 2001, Carla Del Ponte
Carla Del Ponte
Carla Del Ponte is a former Chief Prosecutor of two United Nations international criminal law tribunals. A former Swiss attorney general, she was appointed prosecutor for the International Criminal Tribunal for the former Yugoslavia and the International Criminal Tribunal for Rwanda in August...

, then the chief prosecutor for the International Criminal Tribunal for the Former Yugoslavia
International Criminal Tribunal for the former Yugoslavia
The International Tribunal for the Prosecution of Persons Responsible for Serious Violations of International Humanitarian Law Committed in the Territory of the Former Yugoslavia since 1991, more commonly referred to as the International Criminal Tribunal for the former Yugoslavia or ICTY, is a...

, said that NATO's use of depleted uranium in former Yugoslavia
Former Yugoslavia
The former Yugoslavia is a term used to describe the present day states which succeeded the collapse of the Socialist Federal Republic of Yugoslavia....

 could be investigated as a possible war crime
War crime
War crimes are serious violations of the laws applicable in armed conflict giving rise to individual criminal responsibility...

. Louise Arbour
Louise Arbour
Louise Arbour, is the former UN High Commissioner for Human Rights, a former justice of the Supreme Court of Canada and the Court of Appeal for Ontario and a former Chief Prosecutor of the International Criminal Tribunals for the former Yugoslavia and Rwanda...

, Del Ponte's predecessor as chief prosecutor, had created a small, internal committee, made up of staff lawyers, to assess the allegation. Their findings, that were accepted and endorsed by Del Ponte, concluded that:

Requests for a moratorium on military use

Some states and the International Coalition to Ban Uranium Weapons
International Coalition to Ban Uranium Weapons
The International Coalition to Ban Uranium Weapons is a global coalition of 155 groups in 32 countries. ICBUW was formed in 2003 in Berlaar, Belgium to promote a campaign based on reliable information on depleted uranium weapons at a time when the most vocal opposition to uranium weapons had...

, a coalition of more than 155 non-governmental organization
Non-governmental organization
A non-governmental organization is a legally constituted organization created by natural or legal persons that operates independently from any government. The term originated from the United Nations , and is normally used to refer to organizations that do not form part of the government and are...

s, have asked for a ban on the production and military use of depleted uranium weapons.

The European Parliament
European Parliament
The European Parliament is the directly elected parliamentary institution of the European Union . Together with the Council of the European Union and the Commission, it exercises the legislative function of the EU and it has been described as one of the most powerful legislatures in the world...

 has repeatedly passed resolutions requesting an immediate moratorium
Moratorium (law)
A moratorium is a delay or suspension of an activity or a law. In a legal context, it may refer to the temporary suspension of a law to allow a legal challenge to be carried out....

 on the further use of depleted uranium ammunition, but France
France
The French Republic , The French Republic , The French Republic , (commonly known as France , is a unitary semi-presidential republic in Western Europe with several overseas territories and islands located on other continents and in the Indian, Pacific, and Atlantic oceans. Metropolitan France...

 and Britain
United Kingdom
The United Kingdom of Great Britain and Northern IrelandIn the United Kingdom and Dependencies, other languages have been officially recognised as legitimate autochthonous languages under the European Charter for Regional or Minority Languages...

 – the only EU states that are permanent members of the United Nations Security Council
United Nations Security Council
The United Nations Security Council is one of the principal organs of the United Nations and is charged with the maintenance of international peace and security. Its powers, outlined in the United Nations Charter, include the establishment of peacekeeping operations, the establishment of...

 – have consistently rejected calls for a ban, maintaining that its use continues to be legal, and that the health risks are entirely unsubstantiated.

In 2007 France, Britain, the Netherlands
Netherlands
The Netherlands is a constituent country of the Kingdom of the Netherlands, located mainly in North-West Europe and with several islands in the Caribbean. Mainland Netherlands borders the North Sea to the north and west, Belgium to the south, and Germany to the east, and shares maritime borders...

, and the Czech Republic
Czech Republic
The Czech Republic is a landlocked country in Central Europe. The country is bordered by Poland to the northeast, Slovakia to the east, Austria to the south, and Germany to the west and northwest....

 voted against a United Nations General Assembly
United Nations General Assembly
For two articles dealing with membership in the General Assembly, see:* General Assembly members* General Assembly observersThe United Nations General Assembly is one of the five principal organs of the United Nations and the only one in which all member nations have equal representation...

 resolution to hold a debate in 2009 about the effects of the use of armaments and ammunitions containing depleted uranium. All other European Union nations voted in favour or abstained. The ambassador from the Netherlands explained his negative vote as being due to the reference in the preamble to the resolution "to potential harmful effects of the use of depleted uranium munitions on human health and the environment [which] cannot, in our view, be supported by conclusive scientific studies conducted by relevant international organizations." None of the other permanent members of the United Nations Security Council supported the resolution as China was absent for the vote, Russia abstained and the United States
United States
The United States of America is a federal constitutional republic comprising fifty states and a federal district...

 voted against the resolution.

In September 2008, and in response to the 2007 General Assembly resolution, the UN Secretary General published the views of 15 states alongside those of the International Atomic Energy Agency
International Atomic Energy Agency
The International Atomic Energy Agency is an international organization that seeks to promote the peaceful use of nuclear energy, and to inhibit its use for any military purpose, including nuclear weapons. The IAEA was established as an autonomous organization on 29 July 1957...

 (IAEA) and World Health Organization
World Health Organization
The World Health Organization is a specialized agency of the United Nations that acts as a coordinating authority on international public health. Established on 7 April 1948, with headquarters in Geneva, Switzerland, the agency inherited the mandate and resources of its predecessor, the Health...

 (WHO). The IAEA and WHO evidence differed little from previous statements on the issue. The report was largely split between states concerned about depleted uranium's use such as Finland
Finland
Finland , officially the Republic of Finland, is a Nordic country situated in the Fennoscandian region of Northern Europe. It is bordered by Sweden in the west, Norway in the north and Russia in the east, while Estonia lies to its south across the Gulf of Finland.Around 5.4 million people reside...

, Cuba
Cuba
The Republic of Cuba is an island nation in the Caribbean. The nation of Cuba consists of the main island of Cuba, the Isla de la Juventud, and several archipelagos. Havana is the largest city in Cuba and the country's capital. Santiago de Cuba is the second largest city...

, Japan
Japan
Japan is an island nation in East Asia. Located in the Pacific Ocean, it lies to the east of the Sea of Japan, China, North Korea, South Korea and Russia, stretching from the Sea of Okhotsk in the north to the East China Sea and Taiwan in the south...

, Serbia
Serbia
Serbia , officially the Republic of Serbia , is a landlocked country located at the crossroads of Central and Southeast Europe, covering the southern part of the Carpathian basin and the central part of the Balkans...

, Argentina
Argentina
Argentina , officially the Argentine Republic , is the second largest country in South America by land area, after Brazil. It is constituted as a federation of 23 provinces and an autonomous city, Buenos Aires...

 and predominantly NATO members who do not consider the use of depleted uranium munitions problematic.

In December 2008, 141 states supported a resolution requesting that three UN agencies: United Nations Environment Programme
United Nations Environment Programme
The United Nations Environment Programme coordinates United Nations environmental activities, assisting developing countries in implementing environmentally sound policies and practices. It was founded as a result of the United Nations Conference on the Human Environment in June 1972 and has its...

 (UNEP), WHO and IAEA update their research on the impact of uranium munitions by late 2010 – to coincide with the General Assembly's 65th Session, four voted against, 34 abstained and 13 were absent As before Britain and France voted against the resolution. All other European Union nations voted in favour or abstained: the Netherlands, which voted against a resolution in 2007, voted in favour, as did Finland and Norway
Norway
Norway , officially the Kingdom of Norway, is a Nordic unitary constitutional monarchy whose territory comprises the western portion of the Scandinavian Peninsula, Jan Mayen, and the Arctic archipelago of Svalbard and Bouvet Island. Norway has a total area of and a population of about 4.9 million...

, both of which had abstained in 2007, while the Czech Republic, which voted against the resolution in 2007, abstained. The two other states that voted against the resolution were Israel
Israel
The State of Israel is a parliamentary republic located in the Middle East, along the eastern shore of the Mediterranean Sea...

 and the United States (both of which voted against in 2007), while as before China
China
Chinese civilization may refer to:* China for more general discussion of the country.* Chinese culture* Greater China, the transnational community of ethnic Chinese.* History of China* Sinosphere, the area historically affected by Chinese culture...

 was absent for the vote, and Russia abstained.

On June 21, 2009, Belgium
Belgium
Belgium , officially the Kingdom of Belgium, is a federal state in Western Europe. It is a founding member of the European Union and hosts the EU's headquarters, and those of several other major international organisations such as NATO.Belgium is also a member of, or affiliated to, many...

 became the first country in the world to ban: "inert ammunition and armour that contains depleted uranium or any other industrially manufactured uranium." The move followed a unanimous parliamentary vote on the issue on 22 March 2007. The text of the 2007 law allowed for two years to pass until it came into force. In April 2009, the Belgian Senate voted unanimously to restrict investments by Belgian banks into the manufacturers of depleted uranium weapons.

In September 2009, the Latin American Parliament
Latin American Parliament
The Latin American Parliament , is a regional, permanent organization composed by the countries of Latin America and the Caribbean. It is a consultative assembly similar to the early European Parliament...

 passed a resolution calling for a regional moratorium on the use, production and procurement of uranium weapons. It also called on the Parlatino's members to work towards an international uranium weapons treaty.

In December 2010 the UN General Assembly passed a resolution calling on users of depleted uranium to hand over quantitative and geographical data on their use, to the relevant authorities of affected states when requested to do so. The resolution passed by 148 votes to four, with 30 abstentions. Five states that have abstained on previous resolutions in 2007 and 2008 voted in favour – Belgium, Bosnia & Herzegovina, Greece, Luxembourg and Slovenia, and no former supporters changed position. The UK, US, Israel and France voted against.

In April 2011, the Congress of Costa Rica passed a law prohibiting uranium weapons in its territories, becoming the second country in the world to do so. In November 2010, the Irish Senate also passed a bill seeking to outlaw depleted uranium weapons; it is now expected to be considered by the Dáil
Dáil Éireann
Dáil Éireann is the lower house, but principal chamber, of the Oireachtas , which also includes the President of Ireland and Seanad Éireann . It is directly elected at least once in every five years under the system of proportional representation by means of the single transferable vote...

 before passage into law.

Civilian applications

Depleted uranium has a very high density and is primarily used as shielding material for other radioactive material, and as ballast
Sailing ballast
Ballast is used in sailboats to provide moment to resist the lateral forces on the sail. Insufficiently ballasted boats will tend to tip, or heel, excessively in high winds. Too much heel may result in the boat capsizing. If a sailing vessel should need to voyage without cargo then ballast of...

. Examples include sailboat keel
Keel
In boats and ships, keel can refer to either of two parts: a structural element, or a hydrodynamic element. These parts overlap. As the laying down of the keel is the initial step in construction of a ship, in British and American shipbuilding traditions the construction is dated from this event...

s, as counterweight
Counterweight
A counterweight is an equivalent counterbalancing weight that balances a load.-Uses:A counterweight is often used in traction lifts , cranes and funfair rides...

s and as shielding in industrial radiography
Radiography
Radiography is the use of X-rays to view a non-uniformly composed material such as the human body. By using the physical properties of the ray an image can be developed which displays areas of different density and composition....

 cameras.

Shielding in industrial radiography cameras

Industrial radiography cameras include a very high activity gamma radiation source (typically Ir-192
Iridium
Iridium is the chemical element with atomic number 77, and is represented by the symbol Ir. A very hard, brittle, silvery-white transition metal of the platinum family, iridium is the second-densest element and is the most corrosion-resistant metal, even at temperatures as high as 2000 °C...

 with an activity above 10 TBq). Depleted uranium is often used in the cameras as a shield to protect individuals from the gamma source. Typically the uranium shield is supported and enclosed in polyurethane
Polyurethane
A polyurethane is any polymer composed of a chain of organic units joined by carbamate links. Polyurethane polymers are formed through step-growth polymerization, by reacting a monomer with another monomer in the presence of a catalyst.Polyurethanes are...

 foam for thermal, mechanical and oxidation protection.

Coloring in consumer products

Consumer product uses have included incorporation into dental porcelain
Dental porcelain
Dental porcelain is a porcelain used by a dental technician to create biocompatible lifelike crowns, bridges, and veneers for the patient...

, used for false teeth to simulate the fluorescence of natural teeth, and uranium-bearing reagents used in chemistry laboratories (e.g. uranyl acetate
Uranyl acetate
Uranyl acetate is the acetate salt of uranium and is a yellow crystalline solid made up of yellow rhombic crystals and has a slight acetic odor. Uranyl acetate is slightly radioactive, the precise radioactivity depends on the isotopes of uranium present...

, used in analytical chemistry
Analytical chemistry
Analytical chemistry is the study of the separation, identification, and quantification of the chemical components of natural and artificial materials. Qualitative analysis gives an indication of the identity of the chemical species in the sample and quantitative analysis determines the amount of...

 and as a stain in electron microscopy). Uranium (both depleted uranium and natural uranium) was widely used as a coloring matter for porcelain
Fiestaware
Fiesta is a line of ceramic dinnerware glazed in differing solid colors manufactured and marketed by the Homer Laughlin China Company of Newell, West Virginia....

 and glass
Uranium glass
Uranium glass is glass which has had uranium, usually in oxide diuranate form, added to a glass mix before melting. The proportion usually varies from trace levels to about 2% by weight uranium, although some 19th-century pieces were made with up to 25% uranium.Uranium glass was once made into...

 in the 19th and early to mid 20th century. The practice was largely discontinued in the late 20th century. In 1999 concentrations of 10% depleted uranium were being used in "jaune no.17" a yellow enamel
Vitreous enamel
Vitreous enamel, also porcelain enamel in U.S. English, is a material made by fusing powdered glass to a substrate by firing, usually between 750 and 850 °C...

 powder that was being produced in France
France
The French Republic , The French Republic , The French Republic , (commonly known as France , is a unitary semi-presidential republic in Western Europe with several overseas territories and islands located on other continents and in the Indian, Pacific, and Atlantic oceans. Metropolitan France...

 by Cristallerie de Saint-Paul, a manufacturer of enamel pigment
Pigment
A pigment is a material that changes the color of reflected or transmitted light as the result of wavelength-selective absorption. This physical process differs from fluorescence, phosphorescence, and other forms of luminescence, in which a material emits light.Many materials selectively absorb...

s. The depleted uranium used in the powder was sold by Cogéma's Pierrelatte facility. In February 2000, Cogema discontinued the sale of depleted uranium to producers of enamel and glass.

Trim weights in aircraft

Aircraft that contain depleted uranium trim weights (Boeing 747–100
Boeing 747
The Boeing 747 is a wide-body commercial airliner and cargo transport, often referred to by its original nickname, Jumbo Jet, or Queen of the Skies. It is among the world's most recognizable aircraft, and was the first wide-body ever produced...

 for example) may contain between 400 to 1,500 kg of DU. This application is controversial because the DU may enter the environment if the aircraft were to crash. The metal can also oxidize to a fine powder in a fire. Its use has been phased out in many newer aircraft. Boeing
Boeing
The Boeing Company is an American multinational aerospace and defense corporation, founded in 1916 by William E. Boeing in Seattle, Washington. Boeing has expanded over the years, merging with McDonnell Douglas in 1997. Boeing Corporate headquarters has been in Chicago, Illinois since 2001...

 and McDonnell-Douglas discontinued using DU counterweights in the 1980s. Depleted uranium was released during the crash of El Al Flight 1862
El Al Flight 1862
On 4 October 1992, El Al Flight 1862, a Boeing 747 cargo plane of the Israeli airline El Al, crashed into the Groeneveen and Klein-Kruitberg flats in the Bijlmermeer neighbourhood of Amsterdam, the Netherlands. For the location in the Bijlmermeer, the crash is known in Dutch as the "Bijlmerramp"...

, in which 152 kg was lost, but an extensive study concluded that there was no evidence to link depleted uranium from the plane to any health problems. Counterweights manufactured with cadmium
Cadmium
Cadmium is a chemical element with the symbol Cd and atomic number 48. This soft, bluish-white metal is chemically similar to the two other stable metals in group 12, zinc and mercury. Similar to zinc, it prefers oxidation state +2 in most of its compounds and similar to mercury it shows a low...

 plating
Plating
Plating is a surface covering in which a metal is deposited on a conductive surface. Plating has been done for hundreds of years, but it is also critical for modern technology...

 are considered non-hazardous while the plating is intact.

U.S. NRC general license

U.S. Nuclear Regulatory Commission regulations at 10 CFR 40.25 establish a general license for the use of depleted uranium contained in industrial products or devices for mass-volume applications. This general license allows anyone to possess or use depleted uranium for authorized purposes. Generally, a registration form is required, along with a commitment to not abandon the material. Agreement states may have similar, or more stringent, regulations.

Sailboat keel

Pen Duick VI a boat designed by André Mauric and used for racing, was equipped with a keel in depleted uranium. It was later replaced by a standard lead keel.

Sampling Calorimeters for detectors in high-energy particle physics

Depleted uranium has been used in a number of sampling calorimeters (such as in the D0 and ZEUS detectors) in due to its high density and natural radioactivity.

Health considerations

Normal functioning of the kidney
Kidney
The kidneys, organs with several functions, serve essential regulatory roles in most animals, including vertebrates and some invertebrates. They are essential in the urinary system and also serve homeostatic functions such as the regulation of electrolytes, maintenance of acid–base balance, and...

, brain
Human brain
The human brain has the same general structure as the brains of other mammals, but is over three times larger than the brain of a typical mammal with an equivalent body size. Estimates for the number of neurons in the human brain range from 80 to 120 billion...

, liver
Liver
The liver is a vital organ present in vertebrates and some other animals. It has a wide range of functions, including detoxification, protein synthesis, and production of biochemicals necessary for digestion...

, heart
Human heart
The human heart is a muscular organ that provides a continuous blood circulation through the cardiac cycle and is one of the most vital organs in the human body...

, and numerous other systems can be affected by uranium exposure, because in addition to being weakly radioactive, uranium is a toxic metal
Toxic metal
Toxic metals are metals that form poisonous soluble compounds and have no biological role, i.e. are not essential minerals, or are in the wrong form. Often heavy metals are thought as synonymous, but lighter metals also have toxicity, such as beryllium, and not all heavy metals are particularly...

. DU is less toxic
Toxicity
Toxicity is the degree to which a substance can damage a living or non-living organisms. Toxicity can refer to the effect on a whole organism, such as an animal, bacterium, or plant, as well as the effect on a substructure of the organism, such as a cell or an organ , such as the liver...

 than other heavy metals
Heavy metals
A heavy metal is a member of a loosely-defined subset of elements that exhibit metallic properties. It mainly includes the transition metals, some metalloids, lanthanides, and actinides. Many different definitions have been proposed—some based on density, some on atomic number or atomic weight,...

 such as arsenic
Arsenic
Arsenic is a chemical element with the symbol As, atomic number 33 and relative atomic mass 74.92. Arsenic occurs in many minerals, usually in conjunction with sulfur and metals, and also as a pure elemental crystal. It was first documented by Albertus Magnus in 1250.Arsenic is a metalloid...

 and mercury
Mercury (element)
Mercury is a chemical element with the symbol Hg and atomic number 80. It is also known as quicksilver or hydrargyrum...

. It is weakly radioactive but remains radioactive because of its long half-life
Half-life
Half-life, abbreviated t½, is the period of time it takes for the amount of a substance undergoing decay to decrease by half. The name was originally used to describe a characteristic of unstable atoms , but it may apply to any quantity which follows a set-rate decay.The original term, dating to...

. The Agency for Toxic Substances and Disease Registry
Agency for Toxic Substances and Disease Registry
The Agency for Toxic Substances and Disease Registry is a federal public health agency within the United States Department of Health and Human Services. The agency focuses on minimizing human health risks associated with exposure to hazardous substances...

 states that: "to be exposed to radiation from uranium, you have to eat, drink, or breathe it, or get it on your skin."

However, the Institute of Nuclear Technology-Radiation Protection of Attiki, Greece
Greece
Greece , officially the Hellenic Republic , and historically Hellas or the Republic of Greece in English, is a country in southeastern Europe....

, has noted that "the aerosol produced during impact and combustion of depleted uranium munitions can potentially contaminate wide areas around the impact sites or can be inhaled by civilians and military personnel." The U.S. Department of Defense claims that no human cancer
Cancer
Cancer , known medically as a malignant neoplasm, is a large group of different diseases, all involving unregulated cell growth. In cancer, cells divide and grow uncontrollably, forming malignant tumors, and invade nearby parts of the body. The cancer may also spread to more distant parts of the...

 of any type has been seen as a result of exposure to either natural or depleted uranium.

As early as 1997, British Army doctors warned the British MoD (Ministry of Defence) that exposure to depleted uranium increased the risk of developing lung, lymph and brain cancer, and recommended a series of safety precautions. According to a report issued summarizing the advice of the doctors, 'Inhalation of insoluble uranium dioxide dust will lead to accumulation in the lungs with very slow clearance - if any . . . Although chemical toxicity is low, there may be localised radiation damage of the lung leading to cancer." The report warns that 'All personnel... should be aware that uranium dust inhalation carries a long-term risk... [the dust] has been shown to increase the risks of developing lung, lymph and brain cancers."

Studies using cultured cells and laboratory rodents continue to suggest the possibility of leukemogenic
Leukemia
Leukemia or leukaemia is a type of cancer of the blood or bone marrow characterized by an abnormal increase of immature white blood cells called "blasts". Leukemia is a broad term covering a spectrum of diseases...

, gene
Gene
A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a type of protein or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains...

tic, reproductive, and neurological effects from chronic exposure. In addition, the UK Pensions Appeal Tribunal Service in early 2004 attributed birth defect claims from a February 1991 Gulf War
Gulf War
The Persian Gulf War , commonly referred to as simply the Gulf War, was a war waged by a U.N.-authorized coalition force from 34 nations led by the United States, against Iraq in response to Iraq's invasion and annexation of Kuwait.The war is also known under other names, such as the First Gulf...

 combat veteran to depleted uranium poison
Poison
In the context of biology, poisons are substances that can cause disturbances to organisms, usually by chemical reaction or other activity on the molecular scale, when a sufficient quantity is absorbed by an organism....

ing. Also, a 2005 epidemiology
Epidemiology
Epidemiology is the study of health-event, health-characteristic, or health-determinant patterns in a population. It is the cornerstone method of public health research, and helps inform policy decisions and evidence-based medicine by identifying risk factors for disease and targets for preventive...

 review concluded: "In aggregate the human epidemiological evidence is consistent with increased risk of birth defects in offspring of persons exposed to DU."

Its use in incendiary ammunition is controversial because of potential adverse health effects and its release into the environment. Besides its residual radioactivity, U-238 is a heavy metal whose compounds are known from laboratory studies to be toxic to mammal
Mammal
Mammals are members of a class of air-breathing vertebrate animals characterised by the possession of endothermy, hair, three middle ear bones, and mammary glands functional in mothers with young...

s.

Metallic uranium is prone to slow corrosion
Corrosion
Corrosion is the disintegration of an engineered material into its constituent atoms due to chemical reactions with its surroundings. In the most common use of the word, this means electrochemical oxidation of metals in reaction with an oxidant such as oxygen...

 and small pieces are pyrophoric at room temperature in air. When depleted uranium munitions penetrate armor or burn, they create depleted uranium oxide
Uranium oxide
Uranium oxide is an oxide of the element uranium.The metal uranium forms several oxides:* Uranium dioxide or uranium oxide * Uranium trioxide or uranium oxide...

s in the form of dust that can be inhaled or contaminate wounds. Additionally, fragments of munitions or armor can become embedded in the body.

Chemical toxicity

The chemical toxicity of depleted uranium is about a million times greater in vitro than its radiological hazard. Health effects of DU are determined by factors such as the extent of exposure and whether it was internal or external. Three main pathways exist by which internalization of uranium may occur: inhalation
Inhalation
Inhalation is the movement of air from the external environment, through the air ways, and into the alveoli....

, ingestion
Ingestion
Ingestion is the consumption of a substance by an organism. In animals, it normally is accomplished by taking in the substance through the mouth into the gastrointestinal tract, such as through eating or drinking...

, and embedded fragments or shrapnel
Fragmentation (weaponry)
Fragmentation is the process by which the casing of an artillery shell, bomb, grenade, etc. is shattered by the detonating high explosive filling. The correct technical terminology for these casing pieces is fragments , although shards or splinters can be used for non-preformed fragments...

 contamination. Properties such as phase (e.g. particulate or gaseous), oxidation state (e.g. metallic or ceramic), and the solubility of uranium and its compounds influence their absorption
Absorption (skin)
Skin absorption is a route by which substances can enter the body through the skin. Along with inhalation, ingestion and injection, dermal absorption is a route of exposure for toxic substances and route of administration for medication...

, distribution
Distribution (pharmacology)
Distribution in pharmacology is a branch of pharmacokinetics which describes the reversible transfer of drug from one location to another within the body....

, translocation, elimination
Clearance (medicine)
In medicine, the clearance is a measurement of the renal excretion ability. Although clearance may also involve other organs than the kidney, it is almost synonymous with renal clearance or renal plasma clearance. Each substance has a specific clearance that depends on its filtration characteristics...

 and the resulting toxicity. For example, metallic uranium is less toxic compared to hexavalent uranium(VI) uranyl
Uranyl
The uranyl ion is an oxycation of uranium in the oxidation state +6, with the chemical formula [UO2]2+. It has a linear structure with short U-O bonds, indicative of the presence of multiple bonds between uranium and oxygen. Four or more ligands are bound to the uranyl ion in an equatorial plane...

 compounds such as uranium trioxide
Uranium trioxide
Uranium trioxide , also called uranyl oxide, uranium oxide, and uranic oxide, is the hexavalent oxide of uranium. The solid may be obtained by heating uranyl nitrate to 400 °C. Its most commonly encountered polymorph, γ-UO3, is a yellow-orange powder.-Production and use:There are three methods...

.
Compilation of 2004 Review Information Regarding Uranium Toxicity
Body system Human studies Animal studies In vitro
Renal Elevated levels of protein excretion, urinary catalase and diuresis Damage to Proximal convoluted tubules, necrotic cells cast from tubular epithelium, glomerular changes No studies
Brain/CNS Decreased performance on neurocognitive tests Acute cholinergic toxicity; Dose-dependent accumulation in cortex, midbrain, and vermis; Electrophysiological changes in hippocampus No studies
DNA Increased reports of cancers Increased urine mutagenicity and induction of tumors Binucleated cells with micronuclei, Inhibition of cell cycle kinetics and proliferation; Sister chromatid induction, tumorigenic phenotype
Bone/muscle No studies Inhibition of periodontal bone formation; and alveolar wound healing No studies
Reproductive Uranium miners have more first born female children Moderate to severe focal tubular atrophy; vacuolization of Leydig cells No studies
Lungs/respiratory No adverse health effects reported Severe nasal congestion and hemorrage, lung lesions and fibrosis, edema and swelling, lung cancer No studies
Gastrointestinal Vomiting, diarrhea, albuminuria n/a n/a
Liver No effects seen at exposure dose Fatty livers, focal necrosis No studies
Skin No exposure assessment data available Swollen vacuolated epidermal cells, damage to hair follicles and sebaceous glands No studies
Tissues surrounding embedded DU fragments Elevated uranium urine concentrations Elevated uranium urine concentrations, perturbations in biochemical and neuropsychological testing No studies
Immune system Chronic fatigue, rash, ear and eye infections, hair and weight loss, cough. May be due to combined chemical exposure rather than DU alone No studies No studies
Eyes No studies Conjunctivitis, irritation inflammation, edema, ulceration of conjunctival sacs No studies
Blood No studies Decrease in RBC count and hemoglobin concentration No studies
Cardiovascular Myocarditis resulting from the uranium ingestion, which ended 6 months after ingestion No effects No studies


Uranium is pyrophoric when finely divided. It will corrode under the influence of air and water producing insoluble uranium(IV) and soluble uranium (VI) salts. Soluble uranium salts are toxic. Uranium slowly accumulates in several organs, such as the liver
Liver
The liver is a vital organ present in vertebrates and some other animals. It has a wide range of functions, including detoxification, protein synthesis, and production of biochemicals necessary for digestion...

, spleen
Spleen
The spleen is an organ found in virtually all vertebrate animals with important roles in regard to red blood cells and the immune system. In humans, it is located in the left upper quadrant of the abdomen. It removes old red blood cells and holds a reserve of blood in case of hemorrhagic shock...

, and kidneys. The World Health Organization
World Health Organization
The World Health Organization is a specialized agency of the United Nations that acts as a coordinating authority on international public health. Established on 7 April 1948, with headquarters in Geneva, Switzerland, the agency inherited the mandate and resources of its predecessor, the Health...

 has established a daily "tolerated intake" of soluble uranium salts for the general public of 0.5 µg/kg body weight, or 35 µg for a 70 kg adult.

Epidemiological studies
Epidemiology
Epidemiology is the study of health-event, health-characteristic, or health-determinant patterns in a population. It is the cornerstone method of public health research, and helps inform policy decisions and evidence-based medicine by identifying risk factors for disease and targets for preventive...

 and toxicological tests
Toxicology
Toxicology is a branch of biology, chemistry, and medicine concerned with the study of the adverse effects of chemicals on living organisms...

 on laboratory animals point to it as being immunotoxic
Immunotoxin
An immunotoxin is a human-made protein that consists of a targeting portion linked to a toxin. When the protein binds to that cell, it is taken in through endocytosis, and the toxin kills the cell...

, teratogenic, neurotoxic, with carcinogen
Carcinogen
A carcinogen is any substance, radionuclide, or radiation that is an agent directly involved in causing cancer. This may be due to the ability to damage the genome or to the disruption of cellular metabolic processes...

ic and leukemogenic potential. A 2005 report by epidemiologists concluded: "the human epidemiological evidence is consistent with increased risk of birth defects in offspring of persons exposed to DU."

Early studies of depleted uranium aerosol exposure assumed that uranium combustion product particles would quickly settle out of the air and thus could not affect populations more than a few kilometers from target areas, and that such particles, if inhaled, would remain undissolved in the lung for a great length of time and thus could be detected in urine. Burning uranium droplets violently produce a gaseous vapor comprising about half of the uranium in their original mass. Uranyl
Uranyl
The uranyl ion is an oxycation of uranium in the oxidation state +6, with the chemical formula [UO2]2+. It has a linear structure with short U-O bonds, indicative of the presence of multiple bonds between uranium and oxygen. Four or more ligands are bound to the uranyl ion in an equatorial plane...

 ion contamination in uranium oxides has been detected in the residue of DU munitions fires.

Radiological hazards

External exposure to radiation from pure depleted uranium is less of a concern, because the alpha particle
Alpha particle
Alpha particles consist of two protons and two neutrons bound together into a particle identical to a helium nucleus, which is classically produced in the process of alpha decay, but may be produced also in other ways and given the same name...

 emitted by its isotopes travel only a few centimetres in air or can be stopped by a sheet of paper. Also, the low concentration of uranium-235 that remains in depleted uranium emits only a small amount of low-energy
Energy
In physics, energy is an indirectly observed quantity. It is often understood as the ability a physical system has to do work on other physical systems...

 gamma radiation. However, internal alpha radiation exposure from a particle lodged in tissues is a more serious matter, because adjacent tissues will be irradiated.

According to the World Health Organization
World Health Organization
The World Health Organization is a specialized agency of the United Nations that acts as a coordinating authority on international public health. Established on 7 April 1948, with headquarters in Geneva, Switzerland, the agency inherited the mandate and resources of its predecessor, the Health...

, a radiation
Ionizing radiation
Ionizing radiation is radiation composed of particles that individually have sufficient energy to remove an electron from an atom or molecule. This ionization produces free radicals, which are atoms or molecules containing unpaired electrons...

 dose
Dose (biochemistry)
A dose is a quantity of something that may impact an organism biologically; the greater the quantity, the larger the dose. In nutrition, the term is usually applied to how much of a specific nutrient is in a person's diet or in a particular food, meal, or dietary supplement...

 from it would be about 60% of that from purified natural uranium with the same mass; the radiological dangers are lower due to its longer half-life and the removal of the more radioactive isotopes. However, in a matter of a month or so, depleted uranium generates amounts of thorium-234 and protactinium-234 which emit beta particles at almost the same rate as that of the alpha particles from the uranium-238.

Approximately 90 microgram
Microgram
In the metric system, a microgram is a unit of mass equal to one millionth of a gram , or 1/1000 of a milligram. It is one of the smallest units of mass commonly used...

s of natural uranium, on average, exist in the human body as a result of normal intake of water, food and air. Most is in the skeleton
Skeleton
The skeleton is the body part that forms the supporting structure of an organism. There are two different skeletal types: the exoskeleton, which is the stable outer shell of an organism, and the endoskeleton, which forms the support structure inside the body.In a figurative sense, skeleton can...

. The biochemistry
Biochemistry
Biochemistry, sometimes called biological chemistry, is the study of chemical processes in living organisms, including, but not limited to, living matter. Biochemistry governs all living organisms and living processes...

 of depleted uranium is, for all practical purposes, the same as natural uranium.

Gulf War syndrome and soldier complaints

Increased rates of immune system
Immune system
An immune system is a system of biological structures and processes within an organism that protects against disease by identifying and killing pathogens and tumor cells. It detects a wide variety of agents, from viruses to parasitic worms, and needs to distinguish them from the organism's own...

 disorders and other wide-ranging symptoms, including chronic pain, fatigue and memory loss, have been reported in over one quarter of combat veterans of the 1991 Gulf War
Gulf War
The Persian Gulf War , commonly referred to as simply the Gulf War, was a war waged by a U.N.-authorized coalition force from 34 nations led by the United States, against Iraq in response to Iraq's invasion and annexation of Kuwait.The war is also known under other names, such as the First Gulf...

. Combustion products from depleted uranium munitions are being considered as one of the potential causes by the Research Advisory Committee on Gulf War Veterans' Illnesses, as DU was used in 30 mm and smaller caliber machine-gun bullets on a large scale for the first time in the Gulf War. Veterans of the conflicts in the Persian Gulf
Persian Gulf
The Persian Gulf, in Southwest Asia, is an extension of the Indian Ocean located between Iran and the Arabian Peninsula.The Persian Gulf was the focus of the 1980–1988 Iran-Iraq War, in which each side attacked the other's oil tankers...

, Bosnia and Kosovo have been found to have up to 14 times the usual level of chromosome abnormalities in their genes. Serum-soluble genotoxic teratogens produce congenital disorder
Congenital disorder
A congenital disorder, or congenital disease, is a condition existing at birth and often before birth, or that develops during the first month of life , regardless of causation...

s, and in white blood cells causes immune system damage.

Human epidemiological evidence is consistent with increased risk of birth defects in the offspring of persons exposed to DU. A 2001 study of 15,000 February 1991 U.S. Gulf War combat veterans and 15,000 control veterans found that the Gulf War veterans were 1.8 (fathers) to 2.8 (mothers) times more likely to have children with birth defects. After examination of children's medical records two years later, the birth defect rate increased by more than 20%:
"Dr. Kang found that male Gulf War veterans reported having infants with likely birth defects at twice the rate of non-veterans. Furthermore, female Gulf War veterans were almost three times more likely to report children with birth defects than their non-Gulf counterparts. The numbers changed somewhat with medical records verification. However, Dr. Kang and his colleagues concluded that the risk of birth defects in children of deployed male veterans still was about 2.2 times that of non-deployed veterans."


In early 2004, the UK Pensions Appeal Tribunal Service attributed birth defect claims from a February 1991 Gulf War combat veteran to depleted uranium poisoning. Children of British soldiers who fought in wars in which depleted uranium ammunition was used are at greater risk of suffering genetic diseases such as congenital malformations, commonly called "birth defects," passed on by their fathers. In a study of U.K. troops, "Overall, the risk of any malformation among pregnancies reported by men was 50% higher in Gulf War Veterans (GWV) compared with Non-GWVs."

The U.S. Army has commissioned ongoing research into potential risks of depleted uranium and other projectile weapon materials like tungsten, which the U.S. Navy has used in place of DU since 1993. Studies by the U.S. Armed Forces Radiobiology Research Institute conclude that moderate exposures to either depleted uranium or uranium present a significant toxicological
Toxicology
Toxicology is a branch of biology, chemistry, and medicine concerned with the study of the adverse effects of chemicals on living organisms...

 threat.

One particular subgroup of veterans which may be at higher risk comprises those who have internally retained fragments of DU from shrapnel wounds. A laboratory study on rats produced by the Armed Forces Radiobiology Research Institute showed that, after a study period of 6 months, rats treated with depleted uranium coming from implanted pellets, comparable to the average levels in the urine of Desert Storm veterans with retained DU fragments, had developed a significant tendency to lose weight with respect to the control group.

Substantial amounts of uranium were accumulating in their brain
Human brain
The human brain has the same general structure as the brains of other mammals, but is over three times larger than the brain of a typical mammal with an equivalent body size. Estimates for the number of neurons in the human brain range from 80 to 120 billion...

s and central nervous system
Central nervous system
The central nervous system is the part of the nervous system that integrates the information that it receives from, and coordinates the activity of, all parts of the bodies of bilaterian animals—that is, all multicellular animals except sponges and radially symmetric animals such as jellyfish...

s, and showed a significant reduction of neuronal activity in the hippocampus
Hippocampus
The hippocampus is a major component of the brains of humans and other vertebrates. It belongs to the limbic system and plays important roles in the consolidation of information from short-term memory to long-term memory and spatial navigation. Humans and other mammals have two hippocampi, one in...

 in response to external stimuli. The conclusions of the study show that brain damage from chronic uranium intoxication is possible at lower doses than previously thought. Results from computer-based neurocognitive tests performed in 1997 showed an association between uranium in the urine and "problematic performance on automated tests assessing performance efficiency and accuracy."

In 2003 Professor Brian Spratt FRS, chairman of the Royal Society
Royal Society
The Royal Society of London for Improving Natural Knowledge, known simply as the Royal Society, is a learned society for science, and is possibly the oldest such society in existence. Founded in November 1660, it was granted a Royal Charter by King Charles II as the "Royal Society of London"...

's working group on depleted uranium, said: "The question of who carries out the initial monitoring and clean-up is a political rather than scientific question," and "the coalition
Multinational force in Iraq
The Multi-National Force – Iraq was a military command, led by the United States, which was responsible for Operation Iraqi Freedom. Multi-National Force – Iraq replaced the previous force, Combined Joint Task Force 7, on 15 May 2004, and was later itself reorganized into its successor, United...

 needs to acknowledge that depleted uranium is a potential hazard and make in-roads into tackling it by being open about where and how much depleted uranium has been deployed."

Iraqi population

Since 2001, medical personnel at the Basra
Basra
Basra is the capital of Basra Governorate, in southern Iraq near Kuwait and Iran. It had an estimated population of two million as of 2009...

 hospital in southern Iraq have reported a sharp increase in the incidence of child leukemia and genetic malformation among babies born in the decade following the Gulf War. Iraqi doctors attributed these malformations to possible long-term effects of DU, an opinion which was echoed by several newspapers. In 2004, Iraq had the highest mortality rate due to leukemia
Leukemia
Leukemia or leukaemia is a type of cancer of the blood or bone marrow characterized by an abnormal increase of immature white blood cells called "blasts". Leukemia is a broad term covering a spectrum of diseases...

 of any country. The International Coalition to Ban Uranium Weapons
International Coalition to Ban Uranium Weapons
The International Coalition to Ban Uranium Weapons is a global coalition of 155 groups in 32 countries. ICBUW was formed in 2003 in Berlaar, Belgium to promote a campaign based on reliable information on depleted uranium weapons at a time when the most vocal opposition to uranium weapons had...

 (ICBUW) has made a call to support an epidemiological study in the Basra region, as asked for by Iraqi doctors, but no peer-reviewed study has yet been undertaken in Basra.

A medical survey, "Cancer
Cancer
Cancer , known medically as a malignant neoplasm, is a large group of different diseases, all involving unregulated cell growth. In cancer, cells divide and grow uncontrollably, forming malignant tumors, and invade nearby parts of the body. The cancer may also spread to more distant parts of the...

, Infant Mortality
Infant mortality
Infant mortality is defined as the number of infant deaths per 1000 live births. Traditionally, the most common cause worldwide was dehydration from diarrhea. However, the spreading information about Oral Re-hydration Solution to mothers around the world has decreased the rate of children dying...

 and Birth Sex Ratio
Human sex ratio
In anthropology and demography, the human sex ratio is the sex ratio for Homo sapiens . Like most sexual species, the sex ratio is approximately 1:1. In humans the secondary sex ratio is commonly assumed to be 105 boys to 100 girls, an assumption that is a subject of debate in the scientific...

 in Fallujah
Fallujah
Fallujah is a city in the Iraqi province of Al Anbar, located roughly west of Baghdad on the Euphrates. Fallujah dates from Babylonian times and was host to important Jewish academies for many centuries....

, Iraq 2005–2009" published in July 2010, states that the “Increase in cancer and birth defects…are alarmingly high” and that infant mortality 2009/2010 has reached 13.6%. The group compares the dramatic increase, five years after the actual war 2004, or exposure, with the lymphoma
Lymphoma
Lymphoma is a cancer in the lymphatic cells of the immune system. Typically, lymphomas present as a solid tumor of lymphoid cells. Treatment might involve chemotherapy and in some cases radiotherapy and/or bone marrow transplantation, and can be curable depending on the histology, type, and stage...

 Italian peacekeepers developed after the Balkan wars
Balkan Wars
The Balkan Wars were two conflicts that took place in the Balkans in south-eastern Europe in 1912 and 1913.By the early 20th century, Montenegro, Bulgaria, Greece and Serbia, the countries of the Balkan League, had achieved their independence from the Ottoman Empire, but large parts of their ethnic...

, and the increased cancer risk in certain parts of Sweden
Sweden
Sweden , officially the Kingdom of Sweden , is a Nordic country on the Scandinavian Peninsula in Northern Europe. Sweden borders with Norway and Finland and is connected to Denmark by a bridge-tunnel across the Öresund....

 due to the Chernobyl
Chernobyl
Chernobyl or Chornobyl is an abandoned city in northern Ukraine, in Kiev Oblast, near the border with Belarus. The city had been the administrative centre of the Chernobyl Raion since 1932....

 fallout. The origin and time of introduction of the carcinogenic agent
Carcinogen
A carcinogen is any substance, radionuclide, or radiation that is an agent directly involved in causing cancer. This may be due to the ability to damage the genome or to the disruption of cellular metabolic processes...

 causing the genetic
Genetics
Genetics , a discipline of biology, is the science of genes, heredity, and variation in living organisms....

 stress
Stress (biology)
Stress is a term in psychology and biology, borrowed from physics and engineering and first used in the biological context in the 1930s, which has in more recent decades become commonly used in popular parlance...

, the group will address in a separate report.

1999 NATO bombing of Yugoslavia

In 2001, doctors at the Serb-run hospital in Kosovska Mitrovica
Kosovska Mitrovica
Kosovska Mitrovica , is a city and municipality in northern Kosovo. It is the administrative centre of the homonymous district....

 say the number of patients suffering from malignant diseases has increased by 200% since 1998. In the same year, the World Health Organization
World Health Organization
The World Health Organization is a specialized agency of the United Nations that acts as a coordinating authority on international public health. Established on 7 April 1948, with headquarters in Geneva, Switzerland, the agency inherited the mandate and resources of its predecessor, the Health...

 reported that data from Kosovo
Kosovo
Kosovo is a region in southeastern Europe. Part of the Ottoman Empire for more than five centuries, later the Autonomous Province of Kosovo and Metohija within Serbia...

 was inconclusive and called for further studies.

A 2003 study by the United Nations Environment Programme
United Nations Environment Programme
The United Nations Environment Programme coordinates United Nations environmental activities, assisting developing countries in implementing environmentally sound policies and practices. It was founded as a result of the United Nations Conference on the Human Environment in June 1972 and has its...

 (UNEP) in Bosnia and Herzegovina
Bosnia and Herzegovina
Bosnia and Herzegovina , sometimes called Bosnia-Herzegovina or simply Bosnia, is a country in Southern Europe, on the Balkan Peninsula. Bordered by Croatia to the north, west and south, Serbia to the east, and Montenegro to the southeast, Bosnia and Herzegovina is almost landlocked, except for the...

 stated that low levels of contaminate were found in drinking water and air particulate at DU penetrator impact points. The levels were stated as not a cause for alarm. Yet, Pekka Haavisto
Pekka Haavisto
Pekka Haavisto is a Finnish politician representing the Green League. He was re-elected to the Finnish Parliament in the Finnish parliamentary election of March 2007 after an absence of 12 years. He is also a member of the Helsinki City Council.Haavisto was a member of the Parliament of Finland...

, chairman of the UNEP DU projects stated, "The findings of this study stress again the importance of appropriate clean-up and civil protection measures in a post-conflict situation."

Contamination as a result of the Afghan War

The Canadian Uranium Medical Research Centre obtained urine samples from bombed civilian areas in Jalalabad
Jalalabad
Jalalabad , formerly called Adinapour, as documented by the 7th century Hsüan-tsang, is a city in eastern Afghanistan. Located at the junction of the Kabul River and Kunar River near the Laghman valley, Jalalabad is the capital of Nangarhar province. It is linked by approximately of highway with...

 that showed concentrations of 80-400 ng/L of undepleted uranium, far higher than the typical concentration in the British population of ~5 ng/L.

Studies indicating negligible effects

Studies in 2005 and earlier have concluded that DU ammunition has no measurable detrimental health effects.

A 1999 literature review
Literature review
A literature review is a body of text that aims to review the critical points of current knowledge including substantive findings as well as theoretical and methodological contributions to a particular topic...

 conducted by the Rand Corporation stated: "No evidence is documented in the literature of cancer or any other negative health effect related to the radiation received from exposure to depleted or natural uranium, whether inhaled or ingested, even at very high doses," and a RAND report authored by the U.S. Defense department undersecretary charged with evaluating DU hazards considered the debate to be more political than scientific.

A 2001 oncology
Oncology
Oncology is a branch of medicine that deals with cancer...

 study concluded that "the present scientific consensus is that DU exposure to humans, in locations where DU ammunition was deployed, is very unlikely to give rise to cancer induction". Former NATO Secretary General Lord Robertson
George Robertson, Baron Robertson of Port Ellen
George Islay MacNeill Robertson, Baron Robertson of Port Ellen, is a British Labour Party politician who was the tenth Secretary General of the North Atlantic Treaty Organisation, between October 1999 and early January 2004; he succeeded Javier Solana in that position...

 stated in 2001 that "the existing medical consensus is clear. The hazard from depleted uranium is both very limited, and limited to very specific circumstances".

A 2002 study from the Australia
Australia
Australia , officially the Commonwealth of Australia, is a country in the Southern Hemisphere comprising the mainland of the Australian continent, the island of Tasmania, and numerous smaller islands in the Indian and Pacific Oceans. It is the world's sixth-largest country by total area...

n defense ministry concluded that “there has been no established increase in mortality or morbidity in workers exposed to uranium in uranium processing industries... studies of Gulf War veterans show that, in those who have retained fragments of depleted uranium following combat related injury, it has been possible to detect elevated urinary uranium levels, but no kidney toxicity or other adverse health effects related to depleted uranium after a decade of follow-up.” Pier Roberto Danesi, then-director of the International Atomic Energy Agency
International Atomic Energy Agency
The International Atomic Energy Agency is an international organization that seeks to promote the peaceful use of nuclear energy, and to inhibit its use for any military purpose, including nuclear weapons. The IAEA was established as an autonomous organization on 29 July 1957...

 (IAEA) Seibersdorf +Laboratory, stated in 2002 that "There is a consensus now that DU does not represent a health threat".

The IAEA reported in 2003 that, "based on credible scientific evidence, there is no proven link between DU exposure and increases in human cancers or other significant health or environmental impacts," although "Like other heavy metals, DU is potentially poisonous. In sufficient amounts, if DU is ingested or inhaled it can be harmful because of its chemical toxicity. High concentration could cause kidney damage." The IAEA concluded that while depleted uranium is a potential carcinogen
Carcinogen
A carcinogen is any substance, radionuclide, or radiation that is an agent directly involved in causing cancer. This may be due to the ability to damage the genome or to the disruption of cellular metabolic processes...

, there is no evidence that it has been carcinogenic in humans.

A 2005 study by Sandia National Laboratories’ Al Marshall used mathematical models to analyze potential health effects associated with accidental exposure to depleted uranium during the 1991 Gulf War. Marshall’s study concluded that the reports of cancer risks from DU exposure are not supported by his analysis nor by veteran medical statistics. Marshall also examined possible genetic effects due to radiation from depleted uranium. Chemical effects, including potential reproductive issues, associated with depleted uranium exposure were discussed in some detail in a subsequent journal paper.

Atmospheric contamination as a result of military actions

Elevated radiation levels consistent with very low level atmospheric depleted uranium contamination have been found in air samples taken by the UK Atomic Weapons Establishment at several monitoring sites in Britain. These elevated readings appear to coincide with Operation Anaconda
Operation Anaconda
Operation Anaconda took place in early March 2002 in which the United States military and CIA Paramilitary Officers, working with allied Afghan military forces, and other North Atlantic Treaty Organization and non NATO forces attempted to destroy al-Qaeda and Taliban forces in the Shahi-Kot...

 in Afghanistan, and the Shock and Awe bombing campaign at the start of the Second Gulf War.

Other contamination cases

On October 4, 1992, an El Al
El Al
El Al Israel Airlines Ltd , trading as El Al , is the flag carrier of Israel. It operates scheduled domestic and international services and cargo flights to Europe, North America, Africa and the Far East from its main base in Ben Gurion International Airport...

 Boeing 747-F
Boeing 747
The Boeing 747 is a wide-body commercial airliner and cargo transport, often referred to by its original nickname, Jumbo Jet, or Queen of the Skies. It is among the world's most recognizable aircraft, and was the first wide-body ever produced...

 cargo aircraft Flight 1862
El Al Flight 1862
On 4 October 1992, El Al Flight 1862, a Boeing 747 cargo plane of the Israeli airline El Al, crashed into the Groeneveen and Klein-Kruitberg flats in the Bijlmermeer neighbourhood of Amsterdam, the Netherlands. For the location in the Bijlmermeer, the crash is known in Dutch as the "Bijlmerramp"...

, crashed into an apartment building in Amsterdam
Amsterdam
Amsterdam is the largest city and the capital of the Netherlands. The current position of Amsterdam as capital city of the Kingdom of the Netherlands is governed by the constitution of August 24, 1815 and its successors. Amsterdam has a population of 783,364 within city limits, an urban population...

. Local residents and rescue workers complained of various unexplained health issues which were being attributed to the release of hazardous materials during the crash and subsequent fires. Authorities conducted an epidemiological study in 2000 of those believed to be affected by the accident. The study concluded that there was no evidence to link depleted uranium (used as counter balance weights on the elevators of the plane) to any of the reported health complaints.

External links

Scientific bodies

United Nations

Scientific reports
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