Darwin's Black Box
Encyclopedia
Darwin's Black Box: The Biochemical Challenge to Evolution (1996, first edition; 2006, second edition) is a book written by Michael J. Behe
Michael Behe
Michael J. Behe is an American biochemist, author, and intelligent design advocate. He currently serves as professor of biochemistry at Lehigh University in Pennsylvania and as a senior fellow of the Discovery Institute's Center for Science and Culture...

 and published by Free Press
Free Press (publisher)
Free Press is a book publishing imprint of Simon and Schuster. It was founded by Jeremiah Kaplan and Charles Liebman in 1947 and was devoted to sociology and religion titles. It was headquartered in Glencoe, Illinois, where it was known as The Free Press of Glencoe...

 in which he presents his notion of irreducible complexity
Irreducible complexity
Irreducible complexity is an argument by proponents of intelligent design that certain biological systems are too complex to have evolved from simpler, or "less complete" predecessors, through natural selection acting upon a series of advantageous naturally occurring, chance mutations...

 and claims that its presence in many biochemical systems indicates therefore that they must be the result of intelligent design
Intelligent design
Intelligent design is the proposition that "certain features of the universe and of living things are best explained by an intelligent cause, not an undirected process such as natural selection." It is a form of creationism and a contemporary adaptation of the traditional teleological argument for...

 rather than evolutionary processes
Molecular evolution
Molecular evolution is in part a process of evolution at the scale of DNA, RNA, and proteins. Molecular evolution emerged as a scientific field in the 1960s as researchers from molecular biology, evolutionary biology and population genetics sought to understand recent discoveries on the structure...

. In 1993, Behe had written a chapter on blood clotting in Of Pandas and People
Of Pandas and People
Of Pandas and People: The Central Question of Biological Origins is a controversial 1989 school-level textbook written by Percival Davis and Dean H. Kenyon and published by the Texas-based Foundation for Thought and Ethics...

, presenting essentially the same arguments but without the name "irreducible complexity", which he later presented in very similar terms in a chapter in Darwin's Black Box. Behe later agreed that he had written both and agreed to the similarities when he defended intelligent design at the Kitzmiller v. Dover Area School District
Kitzmiller v. Dover Area School District
Tammy Kitzmiller, et al. v. Dover Area School District, et al. was the first direct challenge brought in the United States federal courts testing a public school district policy that required the teaching of intelligent design...

 trial.

The book has been a source of controversy, as the scientific community
Scientific community
The scientific community consists of the total body of scientists, its relationships and interactions. It is normally divided into "sub-communities" each working on a particular field within science. Objectivity is expected to be achieved by the scientific method...

 at large considers many criticisms of evolution or proponents of intelligent design to be religious, creationism
Creationism
Creationism is the religious beliefthat humanity, life, the Earth, and the universe are the creation of a supernatural being, most often referring to the Abrahamic god. As science developed from the 18th century onwards, various views developed which aimed to reconcile science with the Genesis...

, and pseudoscience
Pseudoscience
Pseudoscience is a claim, belief, or practice which is presented as scientific, but which does not adhere to a valid scientific method, lacks supporting evidence or plausibility, cannot be reliably tested, or otherwise lacks scientific status...

. Common criticisms were that Behe's ideas are not falsifiable, that his definition of an irreducibly complex system is ambiguous, and that he ignores previous work in biochemical evolution. Though influential within the intelligent design movement
Intelligent design movement
The intelligent design movement is a neo-creationist religious campaign for broad social, academic and political change to promote and support the idea of "intelligent design," which asserts that "certain features of the universe and of living things are...

 for several years, the book has lost some of its currency as more and more examples given by Behe as evidence of irreducible complexity have been shown to be explicable by known evolutionary mechanisms, something Behe conceded under cross examination while testifying as an expert witness on behalf of the defendants in Kitzmiller v. Dover Area School District.

Overview

The "black box
Black box
A black box is a device, object, or system whose inner workings are unknown; only the input, transfer, and output are known characteristics.The term black box can also refer to:-In science and technology:*Black box theory, a philosophical theory...

" in the title refers to the conceptual tool in which, for one reason or another, the internal workings of a device are taken for granted, so that its function may be discussed.

Behe begins by reminding the general reader of paradigm shift
Paradigm shift
A Paradigm shift is, according to Thomas Kuhn in his influential book The Structure of Scientific Revolutions , a change in the basic assumptions, or paradigms, within the ruling theory of science...

s in the history of science, in which the foundations and assumptions of theories are examined, sometimes resulting in the rejection of an entire theory. Behe suggests that such a paradigm shift in biology (and particularly in evolution
Evolution
Evolution is any change across successive generations in the heritable characteristics of biological populations. Evolutionary processes give rise to diversity at every level of biological organisation, including species, individual organisms and molecules such as DNA and proteins.Life on Earth...

) is imminent due to recent discoveries (circa 1996) in biochemistry. Behe acknowledges acceptance of the Theory of Evolution by "the great majority" of scientists, and states that "most (though not all) do so based on authority."

Behe states that elucidations of the evolutionary history of various biological features typically assume the existence of certain abilities as their starting point, such as Charles Darwin
Charles Darwin
Charles Robert Darwin FRS was an English naturalist. He established that all species of life have descended over time from common ancestry, and proposed the scientific theory that this branching pattern of evolution resulted from a process that he called natural selection.He published his theory...

's example of a cluster of light-sensitive spots evolving into an eye
Human eye
The human eye is an organ which reacts to light for several purposes. As a conscious sense organ, the eye allows vision. Rod and cone cells in the retina allow conscious light perception and vision including color differentiation and the perception of depth...

 via a series of intermediate steps
Evolution of the eye
The evolution of the eye has been a subject of significant study, as a distinctive example of a homologous organ present in a wide variety of taxa. Certain components of the eye, such as the visual pigments, appear to have a common ancestry – that is, they evolved once, before the animals radiated...

. He then points out that Darwin dismissed the need to explain the origin of the 'simple' light-sensitive spot, summarizes the modern understanding of the biochemistry of vision and claims that many other evolutionary explanations face a similar challenge.

Behe next introduces and defines the concept of irreducible complexity
Irreducible complexity
Irreducible complexity is an argument by proponents of intelligent design that certain biological systems are too complex to have evolved from simpler, or "less complete" predecessors, through natural selection acting upon a series of advantageous naturally occurring, chance mutations...

 as a system with a series of parts in which the removal of any part causes the entire system to cease functioning, offering a springloaded-bar mousetrap as a familiar example. In the following chapters, Behe discusses the apparent irreducible complexity of several biological systems, including the cilium
Cilium
A cilium is an organelle found in eukaryotic cells. Cilia are slender protuberances that project from the much larger cell body....

, the bacterial flagellum
Flagellum
A flagellum is a tail-like projection that protrudes from the cell body of certain prokaryotic and eukaryotic cells, and plays the dual role of locomotion and sense organ, being sensitive to chemicals and temperatures outside the cell. There are some notable differences between prokaryotic and...

, blood clotting
Coagulation
Coagulation is a complex process by which blood forms clots. It is an important part of hemostasis, the cessation of blood loss from a damaged vessel, wherein a damaged blood vessel wall is covered by a platelet and fibrin-containing clot to stop bleeding and begin repair of the damaged vessel...

, the immune system
Immune system
An immune system is a system of biological structures and processes within an organism that protects against disease by identifying and killing pathogens and tumor cells. It detects a wide variety of agents, from viruses to parasitic worms, and needs to distinguish them from the organism's own...

 and intracellular gated and vesicular transport. Behe claims the underlying complexity and biochemical mechanisms of the systems are vastly under-appreciated, and identifies other, similar systems.

Behe identifies one of the primary counter-arguments of irreducible complexity, gradual adaptation—that certain systems may have been co-opted from an original, unrelated role to assume a new function as an irreducibly complex system. He counter-argues that though it is impossible to consider all possible roles for any component, it is extremely implausible that components can fortuitously change function within a complex system and that the focus of the theory changes from making to modifying components and recounts unsuccessful attempts to discover evolutionary pathways for complex systems within scientific journal
Scientific journal
In academic publishing, a scientific journal is a periodical publication intended to further the progress of science, usually by reporting new research. There are thousands of scientific journals in publication, and many more have been published at various points in the past...

s. Behe states that though he did identify assertions that evolution had occurred, he found none that had been supported by experiment or calculation, and concludes the book by offering intelligent design
Intelligent design
Intelligent design is the proposition that "certain features of the universe and of living things are best explained by an intelligent cause, not an undirected process such as natural selection." It is a form of creationism and a contemporary adaptation of the traditional teleological argument for...

 as a solution to irreducible complexity.

Reception

Darwin's Black Box was not well received by the scientific community
Scientific community
The scientific community consists of the total body of scientists, its relationships and interactions. It is normally divided into "sub-communities" each working on a particular field within science. Objectivity is expected to be achieved by the scientific method...

, which overwhelmingly rejected Behe's premises and arguments. Kenneth Miller
Kenneth R. Miller
Kenneth Raymond Miller is a biology professor at Brown University. Miller, who is Roman Catholic, is particularly known for his opposition to creationism, including the intelligent design movement...

 described Behe's argument as an updated version of the argument from design
Teleological argument
A teleological or design argument is an a posteriori argument for the existence of God based on apparent design and purpose in the universe. The argument is based on an interpretation of teleology wherein purpose and intelligent design appear to exist in nature beyond the scope of any such human...

 with reference to biochemistry (which was echoed by other reviewers), and also cites areas in biochemistry and the fossil record which demonstrate currently irreducibly complex systems evolving. Miller also describes Behe's theory as unfalsifiable
Falsifiability
Falsifiability or refutability of an assertion, hypothesis or theory is the logical possibility that it can be contradicted by an observation or the outcome of a physical experiment...

, arguing that it arbitrarily ignores evidence that shows the evolution of a biochemical system. On his blog
Pharyngula (blog)
Pharyngula is a blog on FreeThoughtBlogs and ScienceBlogs run by PZ Myers. In 2006, the science journal Nature listed it as the top-ranked blog written by a scientist. Pharyngula also won the 2005 Koufax Award for Best Expert Blog. The blog topics are eclectic, delving into the non-scientific as...

, PZ Myers
PZ Myers
Paul Zachary "PZ" Myers is an American biology professor at the University of Minnesota Morris and the author of the Pharyngula science blog. He is currently an associate professor of biology at UMM, works with zebrafish in the field of evolutionary developmental biology , and also cultivates an...

 described it as "...an example of pseudoscientific dreck that has been enormously influential." In a review for Nature
Nature (journal)
Nature, first published on 4 November 1869, is ranked the world's most cited interdisciplinary scientific journal by the Science Edition of the 2010 Journal Citation Reports...

, Jerry Coyne
Jerry Coyne
-Online articles:* , The New Republic* , The New Republic* , The New Republic* ", The New Republic * -Online articles:* , The New Republic* , The New Republic* , The New Republic* ", The New Republic (Review of Michael Behe's The Edge of Evolution)* -Online articles:* , The New Republic* , The...

 described the book hailing from 'populist' creationism that failed to deal with the evidence for evolution honestly. Coyne also accuses Behe of quote mining and using ad hominem
Ad hominem
An ad hominem , short for argumentum ad hominem, is an attempt to negate the truth of a claim by pointing out a negative characteristic or belief of the person supporting it...

 attacks against scientists while 'timidly accepting' evolution. A review on the pro-evolution website talk.origins
Talk.origins
talk.origins is a moderated Usenet discussion forum concerning the origins of life, and evolution...

, described the book as "...an exposition of the Frontiers of Ignorance" and that within it systems were labeled "irreducibly complex" if Behe was not able to envision a simpler system that still worked. The review also stated that the theory was unfalsifiable
Falsifiability
Falsifiability or refutability of an assertion, hypothesis or theory is the logical possibility that it can be contradicted by an observation or the outcome of a physical experiment...

 (echoing Miller), with faulty logic that worked because Behe did not provide crucial facts that would illustrate its failings. H. Allen Orr
H. Allen Orr
H. Allen Orr is University Professor and Shirley Cox Kearns Professor of Biology at the University of Rochester.- Education and career :He earned his Bachelor’s degree in Biology and Philosophy from the College of William and Mary and his Ph.D. in Biology from the University of Chicago. At...

 has called Behe's argument in the book "...just plain wrong", arguing that gradual adaptation could produce irreducibly complex systems. Orr points to examples of gradual adaptation already known (citing to the work of H. J. Muller
Hermann Joseph Muller
Hermann Joseph Muller was an American geneticist, educator, and Nobel laureate best known for his work on the physiological and genetic effects of radiation as well as his outspoken political beliefs...

 in the early 20th century). Behe is also criticized for claiming a conspiracy of silence
Conspiracy of silence (expression)
The expression conspiracy of silence, or culture of silence, relates to a condition or matter which is known to exist, but by tacit communal unspoken consensus is not talked about or acknowledged. Commonly such matters are considered culturally shameful...

 among scientists regarding the 'failure of Darwinism'.

Richard Dawkins
Richard Dawkins
Clinton Richard Dawkins, FRS, FRSL , known as Richard Dawkins, is a British ethologist, evolutionary biologist and author...

 criticized the book for being logically flawed by setting up a false dichotomy
False dilemma
A false dilemma is a type of logical fallacy that involves a situation in which only two alternatives are considered, when in fact there are additional options...

 in which Darwinian evolution is rejected despite what he sees as an enormous amount of positive evidence due to a single apparent failure to explain irreducible complexity
Irreducible complexity
Irreducible complexity is an argument by proponents of intelligent design that certain biological systems are too complex to have evolved from simpler, or "less complete" predecessors, through natural selection acting upon a series of advantageous naturally occurring, chance mutations...

. Dawkins further commented that it was an argument Darwin himself had anticipated, and that the example of a bacterial flagellum used by Behe had in fact been refuted by Kenneth R. Miller
Kenneth R. Miller
Kenneth Raymond Miller is a biology professor at Brown University. Miller, who is Roman Catholic, is particularly known for his opposition to creationism, including the intelligent design movement...

 in Kitzmiller v. Dover Area School District
Kitzmiller v. Dover Area School District
Tammy Kitzmiller, et al. v. Dover Area School District, et al. was the first direct challenge brought in the United States federal courts testing a public school district policy that required the teaching of intelligent design...

.

Behe has responded to some of these criticisms. The politically conservative
Conservatism
Conservatism is a political and social philosophy that promotes the maintenance of traditional institutions and supports, at the most, minimal and gradual change in society. Some conservatives seek to preserve things as they are, emphasizing stability and continuity, while others oppose modernism...

 magazine National Review
National Review
National Review is a biweekly magazine founded by the late author William F. Buckley, Jr., in 1955 and based in New York City. It describes itself as "America's most widely read and influential magazine and web site for conservative news, commentary, and opinion."Although the print version of the...

voted Darwin's Black Box one of their top 100 non-fiction books of the century.

Views of Creation

In a review of Behe's paper 'Design vs. Randomness in Evolution: Where Do the Data Point?', Denis Lamoureux
Denis Lamoureux
Denis O. Lamoureux is a professor of science and religion at St. Joseph's College at the University of Alberta, Canada. He has doctoral degrees in dentistry, theology, and biology. He is the author of Evolutionary Creation and I love Jesus and I accept evolution. Along with Phillip E...

 criticised Darwin's Black Box as having become central to fundamentalist and evangelical anti-evolution critiques against biological evolution. Behe supports the historically incorrect misrepresentation that Darwin's views on the origin of life were atheistic, when On the Origin of Species repeatedly refers to a Creator in a positive and supportive context as impressing laws on matter. Though Behe has avoided committing himself to the view that God intervenes directly in nature to create purportedly irreducibly complex structures, Darwin's Black Box briefly speculates that Divine intervention might have caused the direct creation of a cell from which all of life evolved, supporting creationist views of miraculous acts of creation, but ironically echoing Darwin's stated "view of life, with its several powers, having been originally breathed into a few forms or into one". Behe's claim that the creation of an original first cell represents a "gap" in the laws of nature needing divine intervention appears to be the problematic God of the gaps
God of the gaps
God of the gaps is a type of theological fallacy in which gaps in scientific knowledge are taken to be evidence or proof of God's existence. The term was invented by Christian theologians not to discredit theism but rather to discourage reliance on teleological arguments for God's existence.-...

 position which is subject to the gaps being filled by scientific discoveries. Behe's thesis that irreducible structures are created in "one fell swoop" is opposed by other biochemists, including many who are devout Christians, and has, it is claimed by some, no support from the fossil record - something Behe would dispute.

Peer review controversy

In 2005, while testifying for the defense in the Dover
Kitzmiller v. Dover Area School District
Tammy Kitzmiller, et al. v. Dover Area School District, et al. was the first direct challenge brought in the United States federal courts testing a public school district policy that required the teaching of intelligent design...

 trial, Behe claimed under oath that the book had received a more thorough peer review
Peer review
Peer review is a process of self-regulation by a profession or a process of evaluation involving qualified individuals within the relevant field. Peer review methods are employed to maintain standards, improve performance and provide credibility...

 than a scholarly article in a refereed journal, a claim which appears to conflict the facts of the book's peer review. Four of the book's five reviewers (Michael Atchison, Robert Shapiro
Robert Shapiro (chemist)
Robert Shapiro was professor emeritus of chemistry at New York University. He is best known for his work on the origin of life, having written two books on the topic: Origins, a Skeptic’s Guide to the Creation of Life on Earth and Planetary Dreams...

, K. John Morrow, and Russell Doolittle
Russell Doolittle
Russell F. Doolittle is an American biochemist at the University of California, San Diego with focus in structure and evolution of proteins. Born in Connecticut, he earned a B.A. in Biology from Wesleyan University in 1952, and an M.A. in Education from Trinity College in 1957. He earned his Ph.D...

) have made statements that contradict or otherwise do not support Behe's claim of the book passing a rigorous peer review.

Michael Atchison: Atchison has stated that he did not review the book at all, but spent 10 minutes on the phone receiving a brief overview of the book which he then endorsed without ever seeing the text.

Robert Shapiro
Robert Shapiro (chemist)
Robert Shapiro was professor emeritus of chemistry at New York University. He is best known for his work on the origin of life, having written two books on the topic: Origins, a Skeptic’s Guide to the Creation of Life on Earth and Planetary Dreams...

: Shapiro has said that he reviewed the book, and while he agreed with some of its analysis of origin-of-life research, he thought its conclusions are false, though the best explanation of the argument from design that was available. Had the book been submitted to a peer-reviewed journal and this comment had appeared, the review provided by Shapiro would have forced the conclusions regarding intelligent design
Intelligent design
Intelligent design is the proposition that "certain features of the universe and of living things are best explained by an intelligent cause, not an undirected process such as natural selection." It is a form of creationism and a contemporary adaptation of the traditional teleological argument for...

 to be changed or removed.

K. John Morrow: Morrow criticized the book as appalling and unsupported, which contributed to the original publisher turning down the book for publication.

Russell Doolittle
Russell Doolittle
Russell F. Doolittle is an American biochemist at the University of California, San Diego with focus in structure and evolution of proteins. Born in Connecticut, he earned a B.A. in Biology from Wesleyan University in 1952, and an M.A. in Education from Trinity College in 1957. He earned his Ph.D...

: Doolittle, upon whom Behe based much of his discussion of blood clotting, described it as misrepresenting many important points and disingenuous, which also contributed to the original publisher turning down the book for publication.

In the same trial, Behe eventually testified under oath that "There are no peer reviewed articles by anyone advocating for intelligent design supported by pertinent experiments or calculations which provide detailed rigorous accounts of how intelligent design of any biological system occurred". The result of the trial was the ruling that intelligent design is not science
Science
Science is a systematic enterprise that builds and organizes knowledge in the form of testable explanations and predictions about the universe...

 and is essentially religious in nature.

External links

The source of this article is wikipedia, the free encyclopedia.  The text of this article is licensed under the GFDL.
 
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