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Cod liver oil

Cod liver oil

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This article is about the fish extract; for the traditional Newfoundland song, see "Cod Liver Oil (song)
Cod Liver Oil (song)
"Cod Liver Oil" is a song about a traditional medicinal drink for many Newfoundlanders. Cod liver oil in the traditional way of manufacture was sun cured and served in bottles in its raw form. The song was written by Johnny Burke , a balladeer from St. John's, Newfoundland...

".


Cod liver oil is a nutritional supplement
Dietary supplement
A dietary supplement, also known as food supplement or nutritional supplement, is a preparation intended to supplement the diet and provide nutrients, such as vitamins, minerals, fiber, fatty acids, or amino acids, that may be missing or may not be consumed in sufficient quantities in a person's diet...

 derived from liver of cod fish. It has high levels of the omega-3 fatty acids, EPA
Eicosapentaenoic acid
Eicosapentaenoic acid is an omega-3 fatty acid. In physiological literature, it is given the name 20:5. It also has the trivial name timnodonic acid...

 and DHA
Docosahexaenoic acid
Docosahexaenoic acid is an omega-3 fatty acid that is a primary structural component of the human brain and retina. In chemical structure, DHA is a carboxylic acid with a 22-carbon chain and six cis double bonds; the first double bond is located at the third carbon from the omega end...

, and very high levels of vitamin A
Vitamin A
Vitamin A is a vitamin that is needed by the retina of the eye in the form of a specific metabolite, the light-absorbing molecule retinal, that is necessary for both low-light and color vision...

 and vitamin D
Vitamin D
Vitamin D is a group of fat-soluble secosteroids. In humans, vitamin D is unique both because it functions as a prohormone and because the body can synthesize it when sun exposure is adequate ....

. It is widely taken to ease the symptoms of arthritis
Arthritis
Arthritis is a form of joint disorder that involves inflammation of one or more joints....

 and for other health benefits. It was once commonly given to child
Child
Biologically, a child is generally a human between the stages of birth and puberty. Some vernacular definitions of a child include the fetus, as being an unborn child. The legal definition of "child" generally refers to a minor, otherwise known as a person younger than the age of majority...

ren, because the high levels of vitamin D in cod liver oil have been shown to prevent rickets
Rickets
Rickets is a softening of bones in children due to deficiency or impaired metabolism of vitamin D, magnesium , phosphorus or calcium, potentially leading to fractures and deformity. Rickets is among the most frequent childhood diseases in many developing countries...

 and other symptoms of vitamin D deficiency
Hypovitaminosis D
Hypovitaminosis D is a deficiency of Vitamin D. It can result from: inadequate nutritional intake of vitamin D coupled with inadequate sunlight exposure , disorders that limit vitamin D absorption, and conditions that impair the conversion of vitamin D into active metabolites including certain...

.

Manufacture


Cod liver oil was traditionally manufactured by filling a wooden barrel with fresh cod livers and seawater and allowing the mixture to ferment for up to a year before removing the oil. Modern cod liver oil is made by cooking the whole cod body tissues
Biological tissue
Tissue is a cellular organizational level intermediate between cells and a complete organism. A tissue is an ensemble of cells, not necessarily identical, but from the same origin, that together carry out a specific function. These are called tissues because of their identical functioning...

 of fatty fish
Fish
Fish are a paraphyletic group of organisms that consist of all gill-bearing aquatic vertebrate animals that lack limbs with digits. Included in this definition are the living hagfish, lampreys, and cartilaginous and bony fish, as well as various extinct related groups...

 during the manufacture of fish meal
Fish meal
Fish meal, or fishmeal, is a commercial product made from both whole fish and the bones and offal from processed fish. It is a brown powder or cake obtained by rendering pressing the cooked whole fish or fish trimmings to remove most of the fish oil and water, and then ground...

.

Therapeutic uses


Cod liver oil is widely taken to ease the pain and joint stiffness associated with arthritis
Arthritis
Arthritis is a form of joint disorder that involves inflammation of one or more joints....

,. It may have a positive effect on heart, bone, as well as helping to repair wounded skin, hair, and nails.

Cod liver oil and fish oil
Fish oil
Fish oil is oil derived from the tissues of oily fish. Fish oils contain the omega-3 fatty acids eicosapentaenoic acid , and docosahexaenoic acid , precursors of certain eicosanoids that are known to reduce inflammation throughout the body, and are thought to have many health benefits.Fish do not...

 are similar, but cod liver oil has much higher levels of vitamins A and D. In fact, levels of vitamin A are usually high enough to reach toxic levels when consumed daily.

Cod liver oil may be an effective complementary measure for long-term treatment of multiple sclerosis
Multiple sclerosis
Multiple sclerosis is an inflammatory disease in which the fatty myelin sheaths around the axons of the brain and spinal cord are damaged, leading to demyelination and scarring as well as a broad spectrum of signs and symptoms...

.

Use of cod liver oil during pregnancy is associated with lower risk of Type I diabetes in the offspring. This effect was found only in mothers taking cod liver oil, not in mothers taking multivitamin supplements. Cod liver oil taken by nursing mothers improves the breast milk by increasing the amount of fatty acids, which promotes brain development, and the amount of vitamin A, which helps prevent infections, but the level of vitamin D is unchanged.

A Norwegian study of more than 68,000 women reported that female cancer patients who took daily cod-liver oil supplements had significantly reduced mortality (25% for all cancers, 45% for lung cancer) compared to women who did not take such supplements.

Adverse effects


Because cod liver oil has a very high level of vitamin A, it is possible to exceed the Recommended Dietary Allowance (RDA) of vitamin A. Vitamin A accumulates in body fat, and can reach harmful levels sufficient to cause hypervitaminosis A
Hypervitaminosis A
Hypervitaminosis A refers to the effects of excessive vitamin A intake.-Presentation:Effects include* Birth defects* Liver problems* Reduced bone mineral density that may result in osteoporosis* Coarse bone growths...

. Pregnant women may want to consider consulting a doctor when taking cod liver oil because of the high amount of natural forms of vitamin A such as retinol
Retinol
Retinol is one of the animal forms of vitamin A. It is a diterpenoid and an alcohol. It is convertible to other forms of vitamin A, and the retinyl ester derivative of the alcohol serves as the storage form of the vitamin in animals....

. High doses of synthetic vitamin A (retinoid
Retinoid
The retinoids are a class of chemical compounds that are related chemically to vitamin A. Retinoids are used in medicine, primarily due to the way they regulate epithelial cell growth....

s) have been shown to cause birth defects.

The risks of hypervitaminosis and of exposure to environmental toxins such as mercury
Mercury (element)
Mercury is a chemical element with the symbol Hg and atomic number 80. It is also known as quicksilver or hydrargyrum...

, polychlorinated biphenyl
Polychlorinated biphenyl
Polychlorinated biphenyls are a class of organic compounds with 2 to 10 chlorine atoms attached to biphenyl, which is a molecule composed of two benzene rings. The chemical formula for PCBs is C12H10-xClx...

s (PCBs), dioxins , and other contaminants, are reduced when purification processes are applied to produce refined fish-oil products, which consequently contain raised levels of omega-3 fatty acid
Omega-3 fatty acid
N−3 fatty acids are essential unsaturated fatty acids with a double bond starting after the third carbon atom from the end of the carbon chain....

s, such as EPA
Eicosapentaenoic acid
Eicosapentaenoic acid is an omega-3 fatty acid. In physiological literature, it is given the name 20:5. It also has the trivial name timnodonic acid...

 and DHA
Docosahexaenoic acid
Docosahexaenoic acid is an omega-3 fatty acid that is a primary structural component of the human brain and retina. In chemical structure, DHA is a carboxylic acid with a 22-carbon chain and six cis double bonds; the first double bond is located at the third carbon from the omega end...

.

A high intake of cod liver oil by pregnant women is associated with a nearly fivefold increased risk of gestational hypertension, although this study did not control for mercury, which can be present in harmful amounts in fish and which is another cause of hypertension.

Some urge caution when taking cod liver oil and other fish-based supplements since they may contain elevated levels of toxins such as mercury
Mercury poisoning
Mercury poisoning is a disease caused by exposure to mercury or its compounds. Mercury is a heavy metal occurring in several forms, all of which can produce toxic effects in high enough doses...

 and PCBs
Polychlorinated biphenyl
Polychlorinated biphenyls are a class of organic compounds with 2 to 10 chlorine atoms attached to biphenyl, which is a molecule composed of two benzene rings. The chemical formula for PCBs is C12H10-xClx...

 found in fish. Some supplement companies regularly test cod liver oil for purity. Consumerlab.com tested 44 fish and cod liver oil supplements and found that all were free of detectable levels of mercury.

Other uses


In Newfoundland
Newfoundland and Labrador
Newfoundland and Labrador is the easternmost province of Canada. Situated in the country's Atlantic region, it incorporates the island of Newfoundland and mainland Labrador with a combined area of . As of April 2011, the province's estimated population is 508,400...

, cod liver oil was sometimes used as the liquid base for traditional red ochre paint, the coating of choice for use on outbuildings and work buildings associated with the cod fishery.

See also

  • Vitamin A overdose
  • Shark liver oil
    Shark liver oil
    Shark liver oil is obtained from sharks that are caught for food purposes and are living in cold, deep oceans. The liver oil from sharks has been used by fishermen for centuries as a folk remedy for general health...

  • Haliver oil (from halibut
    Halibut
    Halibut is a flatfish, genus Hippoglossus, from the family of the right-eye flounders . Other flatfish are also called halibut. The name is derived from haly and butt , for its popularity on Catholic holy days...

    ; potent source of vitamin A)