Clathrochelate
Overview
Chelation
Chelation is the formation or presence of two or more separate coordinate bonds between apolydentate ligand and a single central atom....
ligands bind to metals more strongly than related monodentate ligands, and macrocyclic ligands
Macrocycle
A macrocycle is, as defined by IUPAC, "a cyclic macromolecule or a macromolecular cyclic portion of a molecule." In the chemical literature, organic chemists may consider any molecule containing a ring of nine or more atoms to be a macrocycle...
bind more strongly than typical chelating ligands. It follows, that bi- or polymacrocyclic ligands would bind to metals particularly strongly. Clathrochelates are usually derived from bimacrocyclic ligands.
The first examples were derived from the tris(dioximate
Dimethylglyoxime
Dimethylglyoxime is a chemical compound described by the formula CH3CCCH3. This colourless solid is the dioxime derivative of the diketone diacetyl . DmgH2 is used in the analysis of palladium or nickel. Its coordination complexes are of theoretical interest as models for enzymes and as catalysts...
)s of cobalt(II) and iron(II).
