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Clandestine chemistry



 
 
Clandestine chemistry is to chemistry
Chemistry

Chemistry is the science concerned with the composition, structure, and properties of matter, as well as the changes it undergoes during chemical reactions....
 carried out in secret, and particularly in illegal drug
Illegal drug trade

The illegal drug trade or drug trafficking is a global black market consisting of the cultivation, manufacture, distribution and sale of Law controlled drugs....
 laboratories. Larger labs are usually run by gang
Gang

A gang is a Group of people who through the organization, formation, and establishment of an assemblage share a common Identity . In current usage it typically denotes a organized crime or else a criminal affiliation....
s or organized crime
Organized crime

Organized crime or criminal organizations comprise groups or operations run by crimes, most commonly for the purpose of generating a money profit....
 intending to produce for distribution on the black market. Smaller labs can be run by individual chemists working clandestinely in order to synthesize smaller amounts of controlled substances or simply out of a hobbyist interest in chemistry, often because of the difficulty ascertaining the purity of other, illegally synthesized drugs obtained on the black market.






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Encyclopedia


Clandestine chemistry is to chemistry
Chemistry

Chemistry is the science concerned with the composition, structure, and properties of matter, as well as the changes it undergoes during chemical reactions....
 carried out in secret, and particularly in illegal drug
Illegal drug trade

The illegal drug trade or drug trafficking is a global black market consisting of the cultivation, manufacture, distribution and sale of Law controlled drugs....
 laboratories. Larger labs are usually run by gang
Gang

A gang is a Group of people who through the organization, formation, and establishment of an assemblage share a common Identity . In current usage it typically denotes a organized crime or else a criminal affiliation....
s or organized crime
Organized crime

Organized crime or criminal organizations comprise groups or operations run by crimes, most commonly for the purpose of generating a money profit....
 intending to produce for distribution on the black market. Smaller labs can be run by individual chemists working clandestinely in order to synthesize smaller amounts of controlled substances or simply out of a hobbyist interest in chemistry, often because of the difficulty ascertaining the purity of other, illegally synthesized drugs obtained on the black market. The term "clandestine lab" is generally used in any situation involving the production of illicit compounds, regardless of whether the facilities being used qualify as a true laboratory
Laboratory

A laboratory is a facility that provides controlled conditions in which science research, experiments, and measurement may be performed. The title of laboratory is also used for certain other facilities where the processes or equipment used are similar to those in scientific laboratories....
.

History


Ancient forms of clandestine chemistry included the manufacturing of poison
Poison

In the context of biology, poisons are Chemical substance that can cause disturbances to organisms, usually by chemical reaction or other activity on the molecular scale, when a sufficient quantity is absorbed by an organism....
s.

Another old form of clandestine chemistry is the illegal brewing
Brewing

Brewing is the production of alcoholic beverages and alcohol fuel through fermentation . The term is used for the production of beer, although the word "brewing" is also used to describe the fermentation process used to create wine and mead....
 and distillation
Distillation

Distillation is a method of separation process mixtures based on differences in their Volatility in a boiling liquid mixture. Distillation is a unit operation, or a physical separation process, and not a chemical reaction....
 of alcohol
Alcohol

In chemistry, an alcohol is any organic compound in which a hydroxyl Functional group is bound to a carbon atom of an alkyl or substituted alkyl group....
. This was frequently done to avoid taxation on spirits.

In the United States in the 1920s, alcohol was on prohibition
Prohibition

Prohibition of alcohol, often referred to simply as prohibition, also known as The Noble Experiment, refers to a sumptuary law which prohibits alcohol....
. This opened a door for brewers to supply their own town with alcohol. Just like modern day drug labs, distilleries were placed in rural
Rural

Rural areas are large and isolated areas of a country, often with low populations. Today, 75 percent of the United States' inhabitants live in suburban and urban areas, but cities occupy only 2 percent of the country....
 areas. The term moonshine
Moonshine

}Moonshine is a common term for home-distilled alcoholic beverage, especially in places where this production is illegal.The name is often assumed to be derived from the fact that moonshine producers and smugglers would often work at night ....
 generally referred to "corn whiskey", that is, a whiskey-like liquor made from corn
Maize

Maize , known as corn in some countries, is a cereal domesticated in Mesoamerica and subsequently spread throughout the American continents....
. American-made corn whiskey is now referred to as Bourbon
Bourbon whiskey

Bourbon is an United States whiskey, a type of distilled beverage, made primarily from maize and named for Bourbon County, Kentucky. It has been produced since the 18th century....
.

Precursor chemicals


Prepared substances (as opposed to those that occur naturally in a consumable form, such as cannabis
Cannabis

Cannabis is a genus of flowering plants that includes three putative species, Cannabis sativa L., Cannabis indica Lam., and Cannabis ruderalis Janisch....
 and hallucinogenic mushrooms) require reagents. Some drugs, like cocaine and morphine are extracted from plant sources and refined with aid of chemicals. Semi-synthetic drugs such as heroin
Heroin

Heroin is a opioid synthesized from morphine, a derivative of the opium poppy. It is the 3,6-acetate ester of morphine . The white crystalline form is commonly the hydrochloride salt diacetylmorphine hydrochloride, however heroin Freebase may also appear as a white powder....
 are made starting from alkaloids extracted from plant sources which are the precursors for further synthesis. In the case of heroin, a mixture of alkaloids is extracted from the opium poppy (Papaver somniferum) by placing small incisions in its bulb - a milky fluid bleeds out of the incisions which is left to dry out and scraped of the bulbs, yielding raw opium. Morphine, one of many alkaloids in opium is then extracted out of the opium by precipitation and turned into heroin by heating it with acetic anhydride for several hours. Other drugs (such as methamphetamine
Methamphetamine

is a stimulant and sympathomimetics psychoactive drug. It is a member of the family of phenylethylamines. The levorotary levomethamphetamine is an over-the-counter drug and used in Vicks Inhalers for nasal decongestion and does not possess the Central nervous system activity of dextro or racemic methamphetamine....
 and MDMA) are normally made from commercially available chemicals, though both can also be made from naturally occurring precursors. Methamphetamine is also sometimes made from ephedrine
Ephedrine

Ephedrine is a sympathomimetic amine commonly used as a stimulant, appetite suppressant, concentration aid, decongestant, and to treat hypotension associated with anaesthesia....
, one of the naturally occurring alkaloids in ephedra (Ephedra sinica). MDMA can be made from safrole
Safrole

Safrole is a colorless or slightly yellow oily liquid. It is typically extracted from the root-bark or the fruit of sassafras plants in the form of sassafras oil, or synthesized from other related methylenedioxy compounds....
, the major constituent of several etheric oils like sassafras and brown camphor oil. Governments have adopted a strategy of chemical control as part of their overall drug control and enforcement plans. Chemical control offers a means of attacking illicit drug production and disrupting the process before the drugs have entered the market.

Because many legitimate industrial chemicals are also necessary in the processing and synthesis of most illicitly produced drugs, preventing the diversion of these chemicals from legitimate commerce to illicit drug manufacturing is a difficult job. Governments often place restrictions on the purchase of large quantities of chemicals that can be used in the production of illict drugs, usually requiring licences or permits to ensure that the purchaser has a legitimate need for them. Furthermore, since so many chemicals listed as illicit drug precursors are manufactured all over the world, international cooperation combined with a comprehensive chemical control strategy is essential for chemical control policies to succeed.

Leading suppliers of precursor chemicals


Chemicals critical to the production of cocaine, heroin, and synthetic drugs are produced in many countries throughout the world. Many manufacturers and suppliers exist in Europe, China, India, the United States, and a host of other countries.

Historically, chemicals critical to the synthesis or manufacture of illicit drugs are introduced into various venues via legitimate purchases by companies that are registered and licensed to do business as chemical importers or handlers. Once in a country or state, the chemicals are diverted by rogue importers or chemical companies, by criminal organizations and individual violators, or, more typically seen in an overseas environment, acquired as a result of coercion on the part of drug traffickers. In response to stricter international controls, drug traffickers have increasingly been forced to divert chemicals by mislabeling the containers, forging documents, establishing front companies, using circuitous routing, hijacking shipments, bribing officials, or smuggling products across international borders.

Enforcement of controls on precursor chemicals


Cocaine

Operation Purple is a U.S. DEA
Drug Enforcement Administration

The Drug Enforcement Administration is a United States Department of Justice law enforcement agency tasked with combating War on Drugs Not only is the DEA the lead agency for domestic enforcement of the drug policy of the United States , it also has sole responsibility for coordinating and pursuing U.S....
 driven international chemical control initiative designed to reduce the illicit manufacture of cocaine
Cocaine

Cocaine is a crystalline tropane alkaloid that is obtained from the leaves of the coca plant. The name comes from "coca" in addition to the alkaloid suffix -ine, forming cocaine....
 in the Andean Region, identifying rogue firms and suspect individuals; gathering intelligence on diversion methods, trafficking trends, and shipping routes; and taking administrative, civil and/or criminal action as appropriate. Critical to the success of this operation is the communication network that gives notification of shipments and provides the government of the importer sufficient time to verify the legitimacy of the transaction and take appropriate action. The effects of this initiative have been dramatic and far-reaching. Operation Purple has exposed a significant vulnerability among traffickers, and has grown to include almost thirty nations. According to the DEA, Operation Purple has been highly effective at interfering with cocaine production. However, illicit chemists always find new methods to evade the DEA's scrutiny.

In countries where strict chemical controls have been put in place, illicit drug production has been seriously affected. For example, few of the chemicals needed to process coca leaf into cocaine are manufactured in Bolivia or Peru. Most are smuggled in from neighbouring countries with advanced chemical industries or diverted from a smaller number of licit handlers. Increased interdiction of chemicals in Peru and Bolivia has contributed to final product cocaine from those countries being of lower, minimally oxidized quality.

As a result, Bolivian lab operators are now using inferior substitutes such as cement instead of lime and sodium bicarbonate instead of ammonia, recycled solvents like ether, and are attempting to streamline a production process that virtually eliminates oxidation to produce cocaine base. Some laboratories are not using sulfuric acid during the maceration state; consequently, less cocaine alkaloid is extracted from the leaf, producing less cocaine hydrochloride, the powdered cocaine marketed in the United States. Similarly, heroin-producing countries depend on supplies of acetic anhydride from the international market. This heroin precursor continues to account for the largest volume of internationally seized chemicals, according to the International Narcotics Control Board. Since July 1999, there have been several notable seizures of acetic anhydride in Turkey (amounting to nearly seventeen metric tons) and Turkmenistan (totaling seventy-three metric tons).

Heroin

Acetic anhydride
Acetic anhydride

Acetic anhydride is the chemical compound with the chemical formula 2O. Commonly abbreviated Acetyl2O, it is one of the simplest acid anhydrides and is a widely used reagent in organic synthesis....
 (AA), the most commonly used chemical agent in heroin
Heroin

Heroin is a opioid synthesized from morphine, a derivative of the opium poppy. It is the 3,6-acetate ester of morphine . The white crystalline form is commonly the hydrochloride salt diacetylmorphine hydrochloride, however heroin Freebase may also appear as a white powder....
 processing, is virtually irreplaceable. According to the DEA, Mexico remains the only heroin source route to heroin laboratories in Afghanistan. Authorities in Uzbekistan, Turkmenistan, Kyrgyzstan, and Kazakhstan routinely seize ton-quantity shipments of diverted acetic anhydride.

DEA's Operation Topaz is a coordinated international strategy targeting acetic anhydride. In place since March 2001, a total of thirty-one countries are currently organized participants in the program in addition to regional participants. The DEA reports that as of June 2001, some 125 consignments of acetic anhydride had been tracked totalling 61,890,2223 kilograms. As of July 2001, there has been approximately 20 shipments of AA totalling 185,000 kilograms either stopped or seized.

Methamphetamine

The methamphetamine situation changed in the mid-1990s with the entrance of Mexican organized crime into production and distribution. According to the DEA, the seizure of 3.5 metric tons of pseudoephedrine
Pseudoephedrine

Pseudoephedrine is a sympathomimetic amine amine commonly used as a decongestant. The salts pseudoephedrine hydrochloride and pseudoephedrine sulfate are found in many Over-the-counter drug preparations either as single-ingredient preparations, or more commonly in combination with antihistamines, paracetamol and/or ibuprofen....
 (the primary precursor chemical used in the production of methamphetamine) in Texas revealed that Mexican trafficking groups were producing methamphetamine on an unprecedented scale.

General


The Multilateral Chemical Reporting Initiative encourages governments to exchange information on a voluntary basis in order to monitor international chemical shipments. Over the past decade, key international bodies like the Commission on Narcotic Drugs and the U.N. General Assembly's Special Session (UNGASS) have addressed the issue of chemical diversion in conjunction with U.S. efforts. These organizations raised specific concerns about potassium permanganate and acetic anhydride.

To facilitate the international flow of information about precursor chemicals, the United States, through its relationship with the Inter-American Drug Control Abuse Commission (CICAD), continues to evaluate the use of precursor chemicals and assist countries in strengthening controls. Many nations still lack the capacity to determine whether the import or export of precursor chemicals is related to legitimate needs or illicit drugs. The problem is complicated by the fact that many chemical shipments are either brokered or transshipped through third countries in an attempt to disguise their purpose or destination.

The International Narcotics Control Board
International Narcotics Control Board

The International Narcotics Control Board is the independent and Quasi-judicial body control organ for the implementation of the United Nations drug conventions....
 (INCB) has opted to organize an international conference with the goal of devising a specific action plan to counter the traffic in MDMA precursor chemicals. In July 2001, the INCB requested the assistance of DEA in planning an international conference on preventing the diversion of chemicals used in the production of amphetamine-type stimulants (ATS), including MDMA (ecstasy) and methamphetamine
Methamphetamine

is a stimulant and sympathomimetics psychoactive drug. It is a member of the family of phenylethylamines. The levorotary levomethamphetamine is an over-the-counter drug and used in Vicks Inhalers for nasal decongestion and does not possess the Central nervous system activity of dextro or racemic methamphetamine....
.

Despite this long history of law enforcement actions, restrictions of chemicals, and even covert military actions, it must be noted that many illicit drugs are still widely available all over the world.

Amphetamines


Clandestine chemistry made its mark in the late 1960s when amphetamine
Amphetamine

Amphetamine and related drugs such as methamphetamine are a group of drugs that act by increasing levels of norepinephrine, serotonin, and dopamine in the brain....
s became controlled substances in many countries. Biker
Motorcycle

A motorcycle is a Single track, two-wheeled motor vehicle powered by an Motorcycle engine. Motorcycles vary considerably depending on the task for which they are designed, such as Touring motorcycle travel, navigating Naked bike, Cruiser , Motorcycle sport and Motorbike racing, or off-road conditions....
 gangs including the Hells Angels
Hells Angels

The Hells Angels Motorcycle Club is a world-wide "Motorcycle club#One Percenters" Motorcycle_club#Outlaw_Motorcycle_Gangs whose members typically ride Harley-Davidson motorcycles....
 took control over the manufacture of amphetamines using standard laboratory equipment.

Methamphetamine
Methamphetamine

is a stimulant and sympathomimetics psychoactive drug. It is a member of the family of phenylethylamines. The levorotary levomethamphetamine is an over-the-counter drug and used in Vicks Inhalers for nasal decongestion and does not possess the Central nervous system activity of dextro or racemic methamphetamine....
 was a favorite among biker gangs, but after phenylacetone
Phenylacetone

Phenylacetone, sometimes abbreviated P2P is an organic compound. It is a clear oil with a refractive index of 1.5168. This chemical is used in the manufacture of methamphetamine and amphetamine....
 became a Schedule II controlled immediate precursor in 1979, it was harder for underground
Underground culture

An underground culture is a subculture that exists under the radar of mainstream massmedia and popular culture. It can be associated to a counterculture or an alternative culture, such as the underground culture that emerged along the hippie movement in the late 1960s and 1970s....
 chemist
Chemist

A chemist is a scientist trained in the science of chemistry. Chemists study the composition of matter and its properties such as density, acidity, size and shape....
s to manufacture methamphetamine.

Frustrated, underground chemists searched for alternative methods for producing methamphetamine. The two predominant methods which appeared both involve the reduction of ephedrine
Ephedrine

Ephedrine is a sympathomimetic amine commonly used as a stimulant, appetite suppressant, concentration aid, decongestant, and to treat hypotension associated with anaesthesia....
 or pseudoephedrine
Pseudoephedrine

Pseudoephedrine is a sympathomimetic amine amine commonly used as a decongestant. The salts pseudoephedrine hydrochloride and pseudoephedrine sulfate are found in many Over-the-counter drug preparations either as single-ingredient preparations, or more commonly in combination with antihistamines, paracetamol and/or ibuprofen....
 to methamphetamine. At the time, neither was a watched chemical, and pills containing the substance could be bought by the thousands without raising any kind of suspicion.

In the 1990s, ephedrine / pseudoephedrine became a closely watched precursor by the DEA, making it somewhat more difficult for underground chemists to produce methamphetamine. Many individual States have enacted precursor control laws which limit the sale of over-the-counter cold medications which contain ephedrine or pseudoephedrine.

DEA
Drug Enforcement Administration

The Drug Enforcement Administration is a United States Department of Justice law enforcement agency tasked with combating War on Drugs Not only is the DEA the lead agency for domestic enforcement of the drug policy of the United States , it also has sole responsibility for coordinating and pursuing U.S....
 El Paso Intelligence Center data is showing a distinct downward trend in the seizure of clandestine drug labs for the illicit manufacture of methampetamine from a high of 17,356 in 2003. Lab seizure data for the United States is available from EPIC beginning in 1999 when 7,438 labs were reported to have been seized during that calendar year.

Methamphetamine Lab Seizures in the US
Year Seizures
1999 7,438
2000 9,902
2001 13,357
2002 16,212
2003 17,356
2004 17,710
2005 12,139


Explosives


Clandestine chemistry does not limit itself only to drugs
Recreational drug use

Recreational drug use is the use of psychoactive drugs for recreational purposes rather than for employment, Medicine or Spirituality purposes, although the distinction is not always clear ....
, it is also associated with explosives, and other illegal chemicals. Of the explosives manufactured illegally, nitroglycerin
Nitroglycerin

Nitroglycerin , also known as nitroglycerine, , trinitroglycerin, trinitroglycerine, 1,2,3-trinitroxypropane and glyceryl trinitrate, is a heavy, colorless, oily, explosive liquid obtained by nitration glycerol....
 and acetone peroxide
Acetone peroxide

Acetone peroxide is an organic peroxide and a primary explosive high explosive. It takes the form of a white crystalline powder with a distinctive acrid smell....
 are easiest to produce due to the ease with which the precursors can be acquired.

Uncle Fester
Uncle Fester (author)

Uncle Fester is the author of such controversial books as "Secrets of Methamphetamine Manufacture," and "Silent Death."...
 is a writer who commonly writes about different aspects of clandestine chemistry. Secrets of Methamphetamine Manufacture is among one of his most popular books, and is considered required reading for DEA Agents. More of his books deal with other aspects of clandestine chemistry, including explosives, and poisons. Fester is, however, considered by many to be a faulty and unreliable source for information in regard to the clandestine manufacture of chemicals.

See also

  • Rolling meth lab
    Rolling meth lab

    A rolling meth lab is a transportable laboratory used for the illegal production of methamphetamine. Rolling meth labs are often readily moved to a secluded location to be unpacked to synthesize the drug, such as in a public park, or sometimes set up to render the drug while the lab is traveling in a vehicle....
  • Cold water extraction
    Cold water extraction

    Cold water extraction is the process whereby a substance is extracted from a mixture via cold water. It is a type of Fractional crystallization ....
  • DEA list of chemicals
    DEA list of chemicals

    The United States Drug Enforcement Administration maintains lists regarding not only the classification of illicit drugs . It also maintains List I of chemicals and List II of chemicals, which contain chemicals which are used to manufacture the controlled substances/illicit drugs....
    , the so-called "DEA Watchlist"


External links

  • at Erowid
    Erowid

    Erowid.org, also called The Vaults of Erowid, is an online library of information about psychoactive drug. It provides information about legal and illegal substances, including their desired and adverse effects....


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