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Cerebroside

 

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Cerebroside



 
 
Cerebrosides are glycosphingolipids which are important components in animal muscle
MUSCLE

MUSCLE is public domain, multiple sequence alignment software for protein and nucleotide sequences.MUSCLE is integrated into UGENE bioinformatics tool as a plugin....
 and nerve
Nerve

A nerve is an enclosed, cable-like bundle of Peripheral nervous system axons . A nerve provides a common pathway for the electrochemical nerve impulses that are transmitted along each of the axons....
 cell membrane
Cell membrane

The cell membrane is the interface between the cellular machinery inside the cell and the fluid outside.It is a semipermeable lipid bilayer found in all cell ....
s. Myelin
Myelin

Myelin is an electrically-insulating dielectric material that forms a layer, the myelin sheath. Usually, myelin surrounds only the axon of a neuron....
 is the most well known cerebroside.

They consist of a ceramide
Ceramide

Ceramides are a family of lipid molecules. A ceramide is composed of sphingosine and a fatty acid. Ceramides are found in high concentrations within the cell membrane of cells....
 with a single sugar residue at the 1-hydroxyl moiety. The sugar residue can be either glucose
Glucose

Glucose , a monosaccharide also known as grape sugar, blood sugar, or corn sugar, is a very important carbohydrate in biology....
 or galactose
Galactose

Galactose is a type of Carbohydrate which is less sweetness than glucose. It is considered a nutritive sweetener because it has food energy.Galactan is a polymer of the sugar galactose....
; the two major types are therefore called glucocerebroside
Glucocerebroside

Glucocerebroside is any of the cerebrosides in which the monosaccharide head group is glucose....
s and galactocerebroside
Galactocerebroside

A galactocerebroside is a type of cerebroside consisting of a ceramide with a galactose residue at the 1-hydroxyl moiety.The galactose is cleaved by galactosylceramidase....
s. Galactocerebrosides are typically found in neural tissue, while glucocerebrosides are found in other tissues.








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Cerebrosides are glycosphingolipids which are important components in animal muscle
MUSCLE

MUSCLE is public domain, multiple sequence alignment software for protein and nucleotide sequences.MUSCLE is integrated into UGENE bioinformatics tool as a plugin....
 and nerve
Nerve

A nerve is an enclosed, cable-like bundle of Peripheral nervous system axons . A nerve provides a common pathway for the electrochemical nerve impulses that are transmitted along each of the axons....
 cell membrane
Cell membrane

The cell membrane is the interface between the cellular machinery inside the cell and the fluid outside.It is a semipermeable lipid bilayer found in all cell ....
s. Myelin
Myelin

Myelin is an electrically-insulating dielectric material that forms a layer, the myelin sheath. Usually, myelin surrounds only the axon of a neuron....
 is the most well known cerebroside.

They consist of a ceramide
Ceramide

Ceramides are a family of lipid molecules. A ceramide is composed of sphingosine and a fatty acid. Ceramides are found in high concentrations within the cell membrane of cells....
 with a single sugar residue at the 1-hydroxyl moiety. The sugar residue can be either glucose
Glucose

Glucose , a monosaccharide also known as grape sugar, blood sugar, or corn sugar, is a very important carbohydrate in biology....
 or galactose
Galactose

Galactose is a type of Carbohydrate which is less sweetness than glucose. It is considered a nutritive sweetener because it has food energy.Galactan is a polymer of the sugar galactose....
; the two major types are therefore called glucocerebroside
Glucocerebroside

Glucocerebroside is any of the cerebrosides in which the monosaccharide head group is glucose....
s and galactocerebroside
Galactocerebroside

A galactocerebroside is a type of cerebroside consisting of a ceramide with a galactose residue at the 1-hydroxyl moiety.The galactose is cleaved by galactosylceramidase....
s. Galactocerebrosides are typically found in neural tissue, while glucocerebrosides are found in other tissues.

Role in disease

A defect in the degradation of glucocerebrosides is Gaucher's disease
Gaucher's disease

Gaucher's disease is the most common of the lysosomal storage diseases. It is caused by a deficiency of the enzyme glucocerebrosidase , leading to an accumulation of its substrate, the fatty substance cerebroside ....
..The corresponding defect for galactocerebrosides is Krabbe disease
Krabbe disease

Krabbe disease is a rare, often fatal degenerative disorder that affects the myelin sheath of the nervous system. This condition is inherited in an autosomal recessive pattern....
.

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