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Cerebral palsy



 
 
Cerebral palsy (CP) is an umbrella term
Umbrella term

An umbrella term is a word that provides a superset or wikt:grouping of related concepts, also called a hypernym.For example, cryptology is an umbrella term that encompasses cryptography and cryptanalysis, among other fields....
 encompassing a group of non-progressive, non-contagious conditions that cause physical disability in human development
Human development (biology)

Human development is the process of growing to maturity. In biological terms, this entails growth from a one-celled zygote to an adult human being....
.

Cerebral refers to the cerebrum, which is the affected area of the brain (although the disorder most likely involves connections between the cortex
Cortex

Cortex may mean any of the following:In anatomy:* Cortex , the outermost or superficial layer of an organ, and especially in the brain:...
 and other parts of the brain such as the cerebellum
Cerebellum

The cerebellum is a region of the brain that plays an important role in the integration of perception, coordination and motoneuron control. In order to coordinate motor control, there are many neural pathways linking the cerebellum with the cerebrum motor cortex and the spinocerebellar tract ....
), and palsy
Palsy

In medicine, palsy is the paralysis of a body part, often accompanied by loss of Somatosensory system and by uncontrolled body movements, such as shaking....
 refers to disorder of movement.






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Encyclopedia


Cerebral palsy (CP) is an umbrella term
Umbrella term

An umbrella term is a word that provides a superset or wikt:grouping of related concepts, also called a hypernym.For example, cryptology is an umbrella term that encompasses cryptography and cryptanalysis, among other fields....
 encompassing a group of non-progressive, non-contagious conditions that cause physical disability in human development
Human development (biology)

Human development is the process of growing to maturity. In biological terms, this entails growth from a one-celled zygote to an adult human being....
.

Cerebral refers to the cerebrum, which is the affected area of the brain (although the disorder most likely involves connections between the cortex
Cortex

Cortex may mean any of the following:In anatomy:* Cortex , the outermost or superficial layer of an organ, and especially in the brain:...
 and other parts of the brain such as the cerebellum
Cerebellum

The cerebellum is a region of the brain that plays an important role in the integration of perception, coordination and motoneuron control. In order to coordinate motor control, there are many neural pathways linking the cerebellum with the cerebrum motor cortex and the spinocerebellar tract ....
), and palsy
Palsy

In medicine, palsy is the paralysis of a body part, often accompanied by loss of Somatosensory system and by uncontrolled body movements, such as shaking....
 refers to disorder of movement. CP is caused by damage to the motor control centers of the developing brain and can occur during pregnancy
Pregnancy

Pregnancy is the carrying of one or more offspring, known as a fetus or embryo, inside the uterus of a female. In a pregnancy, there can be multiple gestations, as in the case of twins or Multiple birth....
 (about 75 percent), during childbirth
Childbirth

Childbirth is the culmination of a human pregnancy or gestation period with the delivery of one or more newborn infants from a woman's uterus. The process of normal human childbirth is categorized in three stages of labour: the shortening and dilation of the cervix, descent and delivery of the infant, and delivery of the placenta.....
 (about 5 percent) or after birth (about 15 percent) up to about age three. Further research is needed on adults with CP as the current literature is highly focused on the pediatric patient.

It is a non-progressive disorder, meaning the brain damage does not worsen, but secondary orthopedic difficulties are common. For example, onset of arthritis and osteoporosis can occur much sooner in adults with cerebral palsy. In addition, motor disorder(s) may be accompanied by "disturbances of sensation, cognition, communication, perception, and/or behavior, and/or by a seizure
Seizure

An epileptic seizure is a transient symptom of abnormal, excessive or synchronous neuronal activity in the brain. It can manifest as an alteration in mental state, tonic or clonic movements, convulsions, and various other psychic symptoms ....
 disorder".

There is no known cure for CP. Medical intervention is limited to the treatment and prevention of complications arising from CP's effects. A 2003 study put the economic cost for CP sufferers in the US at $921,000 per case, including lost income.

In another study, the incidence in six countries surveyed was 2.12–2.45 per 1000 live births, indicating a slight rise in recent years. Improvements in neonatal nursing
Neonatal nursing

Neonatal nursing is a List of nursing specialties practice of caring for newborn infants up to 28 days subsequent to birth. There are three different levels of working as a neonatal nurse: Level I consists of caring for healthy newborns, Level II caring for either premature birth or ill newborns, and Level III caring for newborns who cannot...
 have helped reduce the number of babies who develop cerebral palsy, but the survival of babies with very low birth weights has increased, and these babies are more likely to have cerebral palsy.

Classification


CP is divided into three major classifications to describe different movement impairments. These classifications also reflect the areas of the brain that are damaged. The three major classifications are:

Spastic

For details on the most common form of cerebral palsy, see spastic diplegia
Spastic diplegia

Spastic diplegia, historically known as Little's Disease, is a form of cerebral palsy that is a neuromuscular condition of hypertonia and spasticity in the muscles of the lower extremities of the human body, usually those of the legs, Hip and pelvis....
.


Spastic
Spastic

Evolution of the term in the United KingdomIt is generally regarded as having been brought to public knowledge and popularised from its use in the name of The Spastics Society ]], a charity for people with cerebral palsy, which was founded in 1951 and has a reasonably high public profile from its street collections and charity shops....
 cerebral palsy is by far the most common type, occurring in 70% to 80% of all cases. Moreover, spastic CP accompanies one of the other types in 30% of all cases. People with this type are hypertonic
Hypertonia

Hypertonia is an upper motor neuron dysfunction marked by an abnormal increase in tightness of muscle tone and a reduced ability of a muscle to stretching ....
 and have a neuromuscular condition stemming from damage to the corticospinal tract
Corticospinal tract

The corticospinal or pyramidal tract is a collection of axons that travel between the cerebral cortex of the brain and the spinal cord.The corticospinal tract mostly contains motor axons....
 or the motor cortex
Motor cortex

Motor cortex is a term that describes regions of the cerebral cortex involved in the planning, control, and execution of voluntary motion functions....
 that affects the nervous system's ability to receive gamma amino butyric acid in the area(s) affected by the disability. Spastic CP is further classified by topography
Topography

Topography is the study of Earth's surface shape and features or those ofplanets, Natural satellite, and asteroids. It is also the description of such surface shapes and features ....
 dependent on the region of the body affected; these include:

  • Spastic hemiplegia (one side being affected). Generally, injury to muscle-nerves controlled by the brain's left side will cause a right body deficit, and vice versa. Typically, people that have spastic hemiplegia are the most ambulatory, although they generally have dynamic equinus on the affected side and are primarily prescribed ankle-foot orthoses to prevent said equinus.
  • Spastic diplegia
    Spastic diplegia

    Spastic diplegia, historically known as Little's Disease, is a form of cerebral palsy that is a neuromuscular condition of hypertonia and spasticity in the muscles of the lower extremities of the human body, usually those of the legs, Hip and pelvis....
     (the lower extremities are affected with little to no upper-body spasticity). The most common form of the spastic forms. Most people with spastic diplegia are fully ambulatory and have a scissors gait. Flexed knees and hips to varying degrees are common. Hip problems, dislocations, and in three-quarters of spastic diplegics, also strabismus
    Strabismus

    Strabismus is a condition in which the eyes are not properly aligned with each other. It typically involves a lack of coordination between the Muscles of orbits that prevents bringing the gaze of each eye to the same point in space and preventing proper binocular vision, which may adversely affect depth perception....
     (crossed eyes), can be present as well. In addition, these individuals are often nearsighted. The intelligence of a person with spastic diplegia is unaffected by the condition.
  • Spastic quadriplegia (all four limbs affected equally). People with spastic quadriplegia are the least likely to be able to walk, or if they can, to want to walk, because they are too tight and it is too much effort to do so. Some children with quadriplegia also have hemiparetic tremors, an uncontrollable shaking that affects the limbs on one side of the body and impairs normal movement.


Occasionally, terms such as monoplegia
Monoplegia

In medicine, monoplegia is a paralysis of a single Limb , usually an arm. It is frequently associated with cerebral palsy. This is the mildest form of cerebral palsy, and individuals with it generally have a good prognosis for later life....
, paraplegia
Paraplegia

Paraplegia is an impairment in motor and/or sensory function of the lower extremities. It is usually the result of spinal cord injury or a congenital condition such as spina bifida which affects the neural elements of the spinal canal....
, triplegia
Triplegia

Triplegia is a medical condition is which the patient has paralysis of three limbs. It is frequently associated with cerebral palsy, although other medical conditions, such as a stroke, can also lead to it....
, and pentaplegia may also be used to refer to specific manifestations of the spasticity.

Ataxic

Ataxia
Ataxia

Ataxia is a neurology sign and symptom consisting of gross lack of coordination of muscle movements. Ataxia is a non-specific clinical manifestation implying dysfunction of parts of the nervous system that coordinate movement, such as the cerebellum....
 (ICD-10
ICD

The International Statistical Classification of Diseases and Related Health Problems provides codes to classify diseases and a wide variety of signs, symptoms, abnormal findings,...
 G80.4) type symptoms can be caused by damage to the cerebellum
Cerebellum

The cerebellum is a region of the brain that plays an important role in the integration of perception, coordination and motoneuron control. In order to coordinate motor control, there are many neural pathways linking the cerebellum with the cerebrum motor cortex and the spinocerebellar tract ....
. Forms of ataxia are less common types of Cerebral Palsy, occurring in at most 10% of all cases. Some of these individuals have hypotonia
Hypotonia

Hypotonia is a condition of abnormally low muscle tone , often involving reduced muscle strength. Hypotonia is not a specific medical disorder, but a potential manifestation of many different diseases and disorders that affect motor nerve control by the brain or muscle strength....
 and tremor
Tremor

Tremor is an unintentional, somewhat rhythmic, muscle movement involving to-and-fro movements of one or more body parts. It is the most common of all involuntary movements and can affect the hands, arms, head, face, vocal cords, trunk, and legs....
s. Motor skills like writing, typing, or using scissors might be affected, as well as balance, especially while walking. It is common for individuals to have difficulty with visual and/or auditory processing of objects.

Athetoid/dyskinetic

Athetoid or dyskinetic is mixed muscle tone
Muscle tone

In physiology, medicine, and anatomy, muscle tone is the continuous and passive partial contraction of the muscles. It helps maintain neutral spine, and it declines during REM sleep....
—sometimes hypertonia
Hypertonia

Hypertonia is an upper motor neuron dysfunction marked by an abnormal increase in tightness of muscle tone and a reduced ability of a muscle to stretching ....
 and sometimes hypotonia
Hypotonia

Hypotonia is a condition of abnormally low muscle tone , often involving reduced muscle strength. Hypotonia is not a specific medical disorder, but a potential manifestation of many different diseases and disorders that affect motor nerve control by the brain or muscle strength....
 (Hypotonia will usually occur before 1 year old; the muscle tone will be increased with age and progress to Hypertonia). People with athetoid CP have trouble holding themselves in an upright, steady position for sitting or walking, and often show involuntary motions. For some people with athetoid CP, it takes a lot of work and concentration to get their hand to a certain spot (like scratching their nose or reaching for a cup). Because of their mixed tone and trouble keeping a position, they may not be able to hold onto objects (such as a toothbrush or pencil). About one quarter of all people with CP have athetoid CP. The damage occurs to the extrapyramidal motor system and/or pyramidal tract and to the basal ganglia
Basal ganglia

The basal ganglia are a group of Nucleus in the brain interconnected with the cerebral cortex, thalamus and brainstem. Mammalian basal ganglia are associated with a variety of functions: motor control, cognition, emotions, and learning....
. It occurs in 40% of all cases.

Incidence and prevalence

In the industrialised world, the incidence
Incidence (epidemiology)

Incidence is a measure of the risk of developing some new condition within a specified period of time. Although sometimes loosely expressed simply as the number of new cases during some time period, it is better expressed as a proportion or a rate with a denominator....
 of cerebral palsy is about 2 per 1000 live births. The incidence is higher in males than in females; the Surveillance of Cerebral Palsy in Europe (SCPE) reports a M:F ratio of 1.33:1. Variances in reported rates of incidence across different geographical areas in industrialised countries are thought to be caused primarily by discrepancies in the criteria used for inclusion and exclusion. When such discrepancies are taken into account in comparing two or more registers of patients with cerebral palsy (for example, the extent to which children with mild cerebral palsy are included), the incidence rates converge toward the average rate of 2:1000.

In the United States, approximately 10,000 infants and babies are diagnosed with CP each year, and 1200–1500 are diagnosed at preschool age.

Overall, advances in care of pregnant mothers and their babies has not resulted in a noticeable decrease in CP. This is generally attributed to medical advances in areas related to the care of premature babies (which results in a greater survival rate). Only the introduction of quality medical care to locations with less-than-adequate medical care has shown any decreases. The incidence of CP increases with premature or very low-weight babies regardless of the quality of care.

Prevalence
Prevalence

In epidemiology, the prevalence of a disease in a statistical population is defined as the total number of cases of the disease in the population at a given time, or the total number of cases in the population, divided by the number of individuals in the population....
 of cerebral palsy is best calculated around the school entry age of about six years, the prevalence in the U.S. is estimated to be 2.4 out of 1000 children

The SCPE reported the following incidence of comorbidities in children with CP (the data are from 1980–1990 and included over 4,500 children over age 4 whose CP was acquired during the prenatal or neonatal period):

  • Mental retardation (IQ < 50): 31%
  • Active seizures: 21%
  • Mental retardation (IQ < 50) and not walking: 20%
  • Blindness: 11%


The SCPE noted that the incidence of comorbidities is difficult to measure accurately, particularly across centers. For example, the actual rate of mental retardation may be difficult to determine, as the physical and communicational limitations of people with CP would likely lower their scores on an IQ test if they were not given a correctly modified version.

Apgar scores have sometimes been used as one factor to predict whether or not an individual will develop CP.

Symptoms


All types of CP are characterized by abnormal muscle tone(i.e. slouching over while sitting), reflexes, or motor development and coordination. There can be joint and bone deformities and contractures (permanently fixed, tight muscles and joints). The classical symptoms are spasticities, spasms, other involuntary movements (e.g. facial gestures), unsteady gait, problems with balance, and/or soft tissue findings consisting largely of decreased muscle mass. Scissor walking (where the knees come in and cross) and toe walking (which can contribute to a gait reminiscent of a marionette) are common among people with CP who are able to walk, but taken on the whole, CP symptomatology is very diverse. The effects of cerebral palsy fall on a continuum of motor dysfunction which may range from virtually unnoticeable to "clumsy" and awkward movements on one end of the spectrum to such severe impairments that coordinated movements are almost impossible on the other end of the spectrum.

Babies born with severe CP often have an irregular posture; their bodies may be either very floppy or very stiff. Birth defects, such as spinal curvature, a small jawbone, or a small head sometimes occur along with CP. Symptoms may appear, change, or become more severe as a child gets older. Some babies born with CP do not show obvious signs right away.

Secondary conditions can include seizures, epilepsy
Epilepsy

Epilepsy is a common chronic neurological disorder characterized by recurrent unprovoked seizure s. These seizures are transient signs and/or symptoms of abnormal, excessive or synchronous neuronal activity in the brain....
, speech or communication disorders, eating problems, sensory impairments, mental retardation
Mental retardation

Mental retardation is a generalized, triarchic disorder, characterized by subaverage cognitive functioning and deficits in two or more adaptive behaviors with onset before the age of 18....
, learning disabilities, and/or behavioral disorders.

History

CP, then known as "Cerebral Paralysis", was first identified by English surgeon William Little
William Little (English surgeon)

William John Little was an English surgery who, in the 1860s, identified spastic diplegia in children. He suffered childhood poliomyelitis with residual left lower extremity paraparesis, complicated by severe talipes....
 in 1860. Little raised the possibility of asphyxia
Asphyxia

Asphyxia is a condition of severely deficient supply of oxygen to the body that arises from being unable to breathe normally. An example of asphyxia is choking....
 during birth as a chief cause of the disorder. It was not until 1897 that Sigmund Freud
Sigmund Freud

Sigmund Freud , born Sigismund Schlomo Freud , was an Austrian psychiatrist who founded the psychoanalysis of psychology. Freud is best known for his theories of the unconscious mind and the defense mechanism of Psychological repression and for creating the clinical practice of psychoanalysis for curing psychopathology through dialogue...
, then a neurologist, suggested that a difficult birth was not the cause but rather only a symptom of other effects on fetal development. Research conducted during the 1980s by the National Institute of Neurological Disorders and Stroke (NINDS) suggested that only a small number of cases of CP are caused by lack of oxygen during birth.

Causes

Despite years of debate, the cause of the majority of cases of CP is uncertain.

Some contributing causes of CP are asphyxia
Asphyxia

Asphyxia is a condition of severely deficient supply of oxygen to the body that arises from being unable to breathe normally. An example of asphyxia is choking....
, hypoxia
Hypoxia (medical)

Hypoxia is a Pathology condition in which the body as a whole or a region of the body is deprived of adequate oxygen supply. Variations in arterial oxygen concentrations can be part of the normal physiology, for example, during strenuous physical exercise....
 of the brain, birth trauma, premature birth
Premature birth

In humans, preterm birth refers to the birth of a baby of less than 37 weeks gestational age. Premature birth, commonly used as a synonym for preterm birth, refers to the birth of a premature infant....
, central nervous system infection
Infection

An infection is the detrimental colonization of a host organism by a foreign species. In an infection, the infecting organism seeks to utilize the host resources to multiply ....
s and certain infections in the mother during and before birth. CP is also more common in multiple birth
Multiple birth

A multiple birth occurs when more than one fetus is carried to term in a single pregnancy. Different names for multiple births are used, depending on the number of offspring....
.

Studies at the University of Liverpool
University of Liverpool

The University of Liverpool is a university in the city of Liverpool, England. It is a member of the Russell Group, and founded in 1881 it is also one of the six original "red brick university" civic universities....
 have led to the hypothesis that many cases of cerebral palsy, and other conditions that an infant has at birth, are caused by the death in very early pregnancy of an identical twin. This may occur when twins have a joint circulation through sharing the same placenta
Placenta

The placenta or afterbirth is a highly vascularized ephemeral organ present in Placentalia vertebrates that connects the developing fetal tissues to the uterine wall....
. Not all identical twins share the same blood supply (monochorionic twins), but if they do, the suggestion is that perturbations in blood flow between them can cause the death of one and damage to the development of the surviving fetus. It is common knowledge amongst obstetricians and midwives that a small dead fetus (fetus papyraceus) may sometimes be found attached to a placenta
Placenta

The placenta or afterbirth is a highly vascularized ephemeral organ present in Placentalia vertebrates that connects the developing fetal tissues to the uterine wall....
 following birth. In the past, this has not been considered important and knowledge of the so called ‘vanishing twin
Vanishing twin

A vanishing twin is a fetus in a multi-gestation pregnancy which dies in utero and is then partially or completely reabsorbed by the mother or twin ....
’ has been suppressed to avoid triggering feelings of loss, grief, or guilt in mothers. The pathological consequences depend on the severity and the stage of development of the fetus when the imbalances in blood flow between the fetuses occur. It has been proposed that such pathology could account, not just for cerebral palsy, but for developmental abnormalities of the eye, heart, and gut, and other specific brain abnormalities such as neuronal migration disorders e.g. lissencephaly
Lissencephaly

Lissencephaly, which literally means smooth brain, is a rare brain formation disorder caused by defective neuronal migration during the 12th to 24th weeks of gestation, resulting in a lack of development of brain folds and grooves ....
 and holoprosencephaly
Holoprosencephaly

Holoprosencephaly is a type of cephalic disorder. This is a disorder characterized by the failure of the prosencephalon to develop. During normal development the forebrain is formed and the face begins to develop in the fifth and sixth weeks of human pregnancy....
, which occur during very early fetal development.

Between 40% and 50% of all children who develop cerebral palsy were born prematurely. Premature infants are vulnerable, in part because their organs are not fully developed, increasing the risk of hypoxic injury to the brain that may manifest as CP. A problem in interpreting this is the difficulty in differentiating between CP caused by damage to the brain that results from inadequate oxygenation and CP that arises from prenatal brain damage that then precipitates premature delivery.

Recent research has demonstrated that intrapartum asphyxia is not the most important cause, probably accounting for no more than 10 percent of all cases; rather, infections in the mother, even infections that are not easily detected, may triple the risk of the child developing the disorder, mainly as the result of the toxicity to the fetal brain of cytokine
Cytokine

Cytokines are a category of signaling molecules that, like hormones and neurotransmitters, are used extensively in cell communication. They are proteins, peptides or glycoproteins....
s that are produced as part of the inflammatory response. Low birthweight is a risk factor for CP—and premature infants usually have low birth weights, less than 2.0 kg, but full-term infants can also have low birth weights. Multiple-birth infants are also more likely than single-birth infants to be born early or with a high birth weight.

After birth, other causes include toxins, severe jaundice
Jaundice

Jaundice, also known as icterus , is a yellowish discoloration of the skin, the conjunctival membranes over the sclera , and other mucous membranes caused by hyperbilirubinemia ....
, lead poisoning
Lead poisoning

Lead poisoning is a medical condition caused by increased levels of the metal lead in the blood. Lead may cause irreversible neurological damage as well as renal disease, cardiovascular effects, and human reproduction toxicity....
, physical brain injury, shaken baby syndrome
Shaken baby syndrome

Shaken baby syndrome is a form of child abuse that occurs when an abuser violently shakes an infant or small child, creating a whiplash -type motion that causes acceleration-deceleration injuries....
, incidents involving hypoxia to the brain (such as near drowning), and encephalitis
Encephalitis

Not to be confused with syphilis, although that can cause encephalitis as well.Encephalitis is an Acute inflammation of the brain.Encephalitis with meningitis is known as meningoencephalitis....
 or meningitis
Meningitis

Meningitis is a medical condition caused by inflammation of the protective membranes covering the brain and spinal cord, known collectively as the meninges....
. The three most common causes of asphyxia in the young child are: choking on foreign objects such as toys and pieces of food; poisoning; and near drowning.

Some structural brain anomalies such as lissencephaly
Lissencephaly

Lissencephaly, which literally means smooth brain, is a rare brain formation disorder caused by defective neuronal migration during the 12th to 24th weeks of gestation, resulting in a lack of development of brain folds and grooves ....
 may present with the clinical features of CP, although whether that could be considered CP is a matter of opinion (some people say CP must be due to brain damage, whereas these people never had a normal brain). Often this goes along with rare chromosome disorders and CP is not genetic or hereditary.

Diagnosis


The diagnosis of cerebral palsy has historically rested on the patient's history and physical examination. Once diagnosed with cerebral palsy, further diagnostic tests are optional. The American Academy of Neurology
American Academy of Neurology

The American Academy of Neurology is a professional society for neurologists and neuroscientists. As a medical specialty society it was established in 1949 by A.B....
 published an article in 2004 reviewing the literature and evidence available on CT
CT

CT or ct may stand for:* The Typographical ligature* Carat , a measure of the purity of gold and platinum alloys* Carat , a unit of mass used for measuring gems and pearls...
 and MRI imaging. They suggested that neuroimaging with CT or MRI is warranted when the etiology
Etiology

Etiology is the study of Causality. The word is derived from the Ancient Greek , aitiologia, "giving a reason for" .The word is most commonly used in medical and philosophical theories, where it is used to refer to the study of why things occur, or even the reasons behind the way that things act, and is used in philosophy, physics, psy...
 of a patient's cerebral palsy has not been established - an MRI is preferred over CT due to diagnostic yield and safety. When abnormal, the neuroimaging study can suggest the timing of the initial damage. The CT or MRI is also capable of revealing treatable conditions, such as hydrocephalus
Hydrocephalus

Hydrocephalus is a term derived from the Greek words "hydro" meaning water, and "cephalus" meaning head, and this condition is sometimes known as "water on the brain"....
, porencephaly
Porencephaly

Porencephaly is a type of cephalic disorder. This is an extremely rare disorder of the central nervous system involving a cyst or cavity in a cerebral hemisphere....
, arteriovenous malformation
Arteriovenous malformation

Arteriovenous malformation or AVM in the majority of cases is a congenital disorder consisting of a connection between veins and arteries, this pathology is universally known because of its occurrence in the central nervous system, but can appear in any location....
, subdural hematoma
Subdural hematoma

A subdural hematoma is a form of traumatic brain injury in which blood gathers within the inner meningeal layer of the dura mater . Unlike in epidural hematomas, which are usually caused by tears in artery, subdural bleeding usually results from tears in veins that cross the subdural space....
s and hygromas, and a vermian tumor (which a few studies suggest are present 5 to 22%). Furthermore, an abnormal neuroimaging study indicates a high likelihood of associated conditions, such as epilepsy
Epilepsy

Epilepsy is a common chronic neurological disorder characterized by recurrent unprovoked seizure s. These seizures are transient signs and/or symptoms of abnormal, excessive or synchronous neuronal activity in the brain....
 and mental retardation
Mental retardation

Mental retardation is a generalized, triarchic disorder, characterized by subaverage cognitive functioning and deficits in two or more adaptive behaviors with onset before the age of 18....
.

Presentation: bones

In order for bones to attain their normal shape and size, they require the stresses from normal musculature. Osseous findings will therefore mirror the specific muscular deficits in a given person with CP. The shafts of the bones are often thin (gracile). When compared to these thin shafts (diaphyses) the metaphyses often appear quite enlarged (ballooning). With lack of use, articular cartilage may atrophy, leading to narrowed joint spaces. Depending on the degree of spasticity, a person with CP may exhibit a variety of angular joint deformities. Because vertebral bodies need vertical gravitational loading forces to develop properly, spasticity and an abnormal gait can hinder proper and/or full bone and skeletal development. People with CP tend to be shorter in height than the average person because their bones are not allowed to grow to their full potential. sometimes bones grow at different lengths, so the person may have one leg longer than the other

Prognosis

CP is not a progressive disorder (meaning the actual brain damage does not worsen), but the symptoms can become worse over time due to subdural damage. A person with the disorder may improve somewhat during childhood if he or she receives extensive care from specialists, but once bones and musculature become more established, orthopedic surgery may be required for fundamental improvement. People who have CP tend to develop arthritis at a younger age than normal because of the pressure placed on joints by excessively toned and stiff muscles.

The full intellectual potential of a child born with CP will often not be known until the child starts school. People with CP are more likely to have some type of learning disability
Learning disability

In the United States and Canada, the terms learning disability, learning disabilities, and learning disorders refer to a group of disorders that affect a broad range of academic and functional skills including the ability to Speech communication, hearing , Reading , writing, spelling, reason and organize information....
, but this is not related to a person's intellect or IQ level. Intellectual level among people with CP varies from genius to mentally retarded, as it does in the general population, and experts have stated that it is important to not underestimate CP sufferer's capabilities and to give them every opportunity to learn.

The ability to live independently with CP also varies widely depending on the severity of the disability. Some individuals with CP will require personal assistant services for all activities of daily living. Others can live semi-independently, needing support only for certain activities. Still others can live in complete independence. The need for personal assistance often changes with increasing age and associated functional decline. However, in most cases persons with CP can expect to have a normal life expectancy; survival has been shown to be associated with the ability to ambulate, roll, and self-feed. As the condition does not directly affect reproductive function, some persons with CP have children and parent successfully.

According to OMIM, only 2% of cases of CP are inherited (with glutamate decarboxylase-1
Glutamate decarboxylase

Glutamate decarboxylase is an enzyme that catalyzes the decarboxylation of glutamate to GABA and CO2. GAD uses Pyridoxal-phosphate as a cofactor....
 as one known enzyme involved.) There is no evidence of an increased chance of a person with CP having a child with CP.

Treatment

There is no cure for CP, but various forms of therapy can help a person with the disorder to function and live more effectively. In general, the earlier treatment begins the better chance children have of overcoming developmental disabilities or learning new ways to accomplish the tasks that challenge them. The earliest proven intervention occurs during the infant's recovery in the neonatal intensive care unit
Neonatal intensive care unit

A neonatal intensive care unit, usually shortened NICU and also called a newborn intensive care unit, intensive care nursery , and special care baby unit , is a unit of a hospital specializing in the care of ill or prematurity newborn infants....
 (NICU)
Neonatal intensive care unit

A neonatal intensive care unit, usually shortened NICU and also called a newborn intensive care unit, intensive care nursery , and special care baby unit , is a unit of a hospital specializing in the care of ill or prematurity newborn infants....
. Treatment may include one or more of the following: physical therapy; occupational therapy; speech therapy; drugs to control seizures, alleviate pain, or relax muscle spasms (e.g. benzodiazepienes, baclofen and intrathecal phenol/baclofen); hyperbaric oxygen; the use of Botox to relax contracting muscles; surgery to correct anatomical abnormalities or release tight muscles; braces and other orthotic devices; rolling walkers; and communication aids such as computers with attached voice synthesizers. For instance, the use of a standing frame
Standing frame

A standing frame is assistive technology used by a child or adult who uses a wheelchair for mobility. A standing frame provides alternative positioning to sitting in a wheelchair by supporting the person in the standing position....
 can help reduce spasticity and improve range of motion
Range of motion

Range of motion or , as used in the biomedical and weightlifting communities, is the measurement of the achievable distance between the flexed position and the extended position of a particular joint or muscle group....
 for people with CP who use wheelchairs. Nevertheless, there is only some benefit from therapy. Treatment is usually symptomatic and focuses on helping the person to develop as many motor skills as possible or to learn how to compensate for the lack of them. Non-speaking people with CP are often successful availing themselves of augmentative and alternative communication
Augmentative and alternative communication

Augmentative and alternative communication refers "to an area of research, clinical, and educational practice. AAC involves attempts to study and when necessary compensate for temporary or permanent impairments, activity limitations, and participation restrictions of individuals with severe disorders of speech-language production and/or comp...
 systems such as Blissymbols
Blissymbols

Blissymbols or Blissymbolics were conceived of as an ideographic writing system consisting of several hundred basic symbols, each representing a concept, which can be composed together to generate new symbols that represent new concepts....
.

Early Nutritional Support In one cohort study
Cohort study

A cohort study or panel study is a form of longitudinal study used in medicine and social science. It is one type of study design and should be compared with a cross-sectional study....
 of 490 premature infants discharged from the NICU, the rate of growth during hospital stay was related to neurological function at 18 and 22 months of age. The study found a significant
Statistical significance

In statistics, a result is called statistically significant if it is unlikely to have occurred by chance. "A statistically significant difference" simply means there is statistical evidence that there is a difference; it does not mean the difference is necessarily large, important, or significant in the common meaning of the word....
 decrease in the incidence
Incidence

Incidence may refer to:* Incidence , a measure of the risk of developing some new condition within a specified period of time* Incidence , the binary relations describing how subsets meet...
 of cerebral palsy in the group of premature infants with the highest growth velocity. This study suggests that adequate nutrition and growth play a protective role in the development of cerebral palsy.

Physical therapy
Physical therapy

Physical therapy is a health care profession which provides services to individuals and populations to develop, maintain and restore maximum movement and functional ability throughout life....
 (PT) programs are designed to encourage the patient to build a strength base for improved gait and volitional movement, together with stretching programs to limit contractures. Many experts believe that life-long physical therapy is crucial to maintain muscle tone, bone structure, and prevent dislocation of the joints.

Occupational therapy
Occupational therapy

File:Occupational therapy psychiatric hospital.jpgOccupational Therapy, often abbreviated as "OT", incorporates meaningful and purposeful occupation to enable people with limitations or impairments to participate in everyday life....
 helps adults and children maximise their function, adapt to their limitations and live as independently as possible.

Orthotic devices
Orthotics

Orthotics is an allied health care medical profession or field that is concerned with the design, development, fitting and manufacturing of orthoses, which are devices that support or correct musculoskeletal deformities and/or abnormalities of the human body....
 such as ankle-foot orthoses
Ankle-foot orthosis

Ankle-foot orthosis is a brace , usually plastic, worn on the lower leg and foot to support the ankle, hold the foot and ankle in the correct position, and correct foot drop....
 (AFOs) are often prescribed to minimise gait irregularities. AFOs have been found to improve several measures of ambulation, including reducing energy expenditure and increasing speed and stride length.

Speech therapy
Speech therapy

#redirect Speech and language pathology...
 helps control the muscles of the mouth and jaw, and helps improve communication. Just as CP can affect the way a person moves their arms and legs, it can also affect the way they move their mouth, face and head. This can make it hard for the person to breathe; talk clearly; and bite, chew and swallow food. Speech therapy often starts before a child begins school and continues throughout the school years.

Advanced Biomechanical Rehabilitation (ABR) ABR is a unique biomechanically based rehabilitation approach for children and young adults with brain injury that brings predictable recovery of musculoskeletal structure and motor functions. ABR improves musculoskeletal structure so significantly that normal motor functions recover spontaneously, making special training and management for "motor disabled" unnecessary.

Hyperbaric oxygen therapy
Hyperbaric oxygen therapy

Hyperbaric medicine, also known as hyperbaric oxygen therapy , is the medical use of oxygen at a level higher than atmospheric pressure....
 Recent studies have demonstrated a dramatic improvement in CP symptomology when hyperbaric oxygen therapy is used as a treatment. In 1989, researchers in Brazil reported an alleviation in symptomology and other characteristics in a study involving 218 cerebral palsy patients. Significant enhancements were documented showing improved vision, hearing and speech as well as a reduction of spasticity by 50%, which occurred in 94% of study patients. Since the publication of the São Paulo review, other studies on the efficacy of hyperbaric oxygenation have been published though the number of subjects have remained low. An editorial published by the Undersea and Hyperbaric Medical Society
Undersea and Hyperbaric Medical Society

The Undersea and Hyperbaric Medical Society is the primary source of information for Diving medicine and hyperbaric medicine medicine physiology worldwide....
 in 2007 reviewed all publications to date and called for further research that will include "basic science research to determine a reasonable mechanism of action" for hyperbaric oxygenation as well as "clinical studies of the highest possible methodological rigor".

Nutritional counseling may help when dietary needs are not met because of problems with eating certain foods.

Both massage therapy and hatha yoga
Hatha yoga

Hatha Yoga , also called Hatha Vidya , is a system of Yoga that introduced by Yogi Swatmarama, a sage of 15th century India, and compiler of the Hatha Yoga Pradipika....
 are designed to help relax tense muscles, strengthen muscles, and keep joints flexible. Hatha yoga breathing exercises are sometimes used to try to prevent lung infections. More research is needed to determine the health benefits of these therapies for people with CP.

Surgery for people with CP usually involves one or a combination of:

  • Loosening tight muscles and releasing fixed joints, most often performed on the hips, knees, hamstrings, and ankles. In rare cases, this surgery may be used for people with stiffness of their elbows, wrists, hands, and fingers.


  • The insertion of a Baclofen Pump usually during the stages while a patient is a young adult. This is usually placed in the left abdomen. It is a pump that is connected to the spinal cord, whereby it sends bits of Baclofen aleiviating the continuous muscle flexation. Baclofen in an of itself is a muscle relaxer and is often given PO to patients to help counter the effects of spasticity.


  • Straightening abnormal twists of the leg bones, i.e. femur (termed femoral anteversion or antetorsion) and tibia (tibial torsion). This is a secondary complication caused by the spastic muscles generating abnormal forces on the bones, and often results in intoeing (pigeon-toed gait). The surgery is called derotation osteotomy, in which the bone is broken (cut) and then set in the correct alignment.


  • Cutting nerves on the limbs most affected by movements and spasms. This procedure, called a rhizotomy
    Rhizotomy

    A rhizotomy is a neurosurgical procedure that selectively severs problematic nerve roots in the spinal cord, most often to relieve the symptoms of neuromuscular conditions such as spastic diplegia and other forms of spastic cerebral palsy....
    , "rhizo" meaning root and "tomy" meaning "a cutting of" from the Greek suffix 'tomia' reduces spasms and allows more flexibility and control of the affected limbs and joints.


  • Botulinum Toxin A (Botox) injections into muscles that are either spastic or have contractures, the aim being to relieve the disability and pain produced by the inappropriately contracting muscle.


Another way is that a new study has found that cooling the bodies and blood of high-risk full-term babies shortly after birth may significantly reduce disability or death.

Cord Blood Therapy: There are no published randomized controlled trials or meta-analysis
Meta-analysis

In statistics, a meta-analysis combines the results of several studies that address a set of related research hypotheses. This is normally done by identification of a common measure of effect size, which is modelled using a form of meta-regression....
 of this treatment modality in cerebral palsy. In March 2008 a boy that was diagnosed with cerebral palsy appeared on the Today Show with his family. The parents noted that he could not walk on his own and appeared to be "swallowing his tongue" at times. He was eventually diagnosed with cerebral palsy and could only walk with the aid of a walker for a short time. Earlier this year he participated in a clinical trial involving his own cord blood that his parents had saved when he was born. Within 5 days after the procedure he was walking on his own and talking, something his mother said he was not capable of on his own and it was doubtful he would ever be able to do on his own. The doctors also told his parents that if his rate of progress continues uninterrupted until he is 7 he will be pronounced cured. The parents message to the audience was "Bank your babies cord blood or donate it if you do not want to keep it. But you never know when you may need it."

Conductive education
Conductive education

Conductive Education , or CE, is an educational system that has been specifically developed for children and adults who have motor disorders of neurological origin such as cerebral palsy....
 (CE) was developed in Hungary from 1945 based on the work of András Peto
András Peto

Professor Andr?s Peto was a practitioner of physiotherapy whose work provided the foundation for conductive education.Between 1930 and 1938, Peto published many literary, philosophical and medical works....
. It is a unified system of rehabilitation for people with neurological disorders including cerebral palsy, Parkinson's disease and multiple sclerosis, amongst other conditions. It is theorised to improve mobility, self-esteem, stamina and independence as well as daily living skills and social skills. The conductor is the professional who delivers CE in partnership with parents and children. Skills learned during CE should be applied to everyday life and can help to develop age-appropriate cognitive, social and emotional skills. It is available at specialised centres.

Biofeedback
Biofeedback

Biofeedback is a form of alternative medicine that involves measuring a subject's quantifiable bodily functions such as blood pressure, heart rate, body temperature, sweating, and muscle tension, conveying the information to the patient in real-time....
 is an alternative therapy
Alternative medicine

The term alternative medicine, as used in the modern western world, encompasses any healing practice "that does not fall within the realm of conventional medicine"....
 in which people with CP learn how to control their affected muscles. Some people learn ways to reduce muscle tension with this technique. Biofeedback does not help everyone with CP.

Neuro - cognitive therapy. A new approach to treating cerebral palsy from [Snowdrop]. It is based upon two proven principles. (1). Neural Plasticity. The brain is capable of altering its own structure and functioning to meet the demands of any particular environment. Consequently if the child is provided with an appropriate neurological environment, he will have the best chance of making progress. (2)Learning can lead development. As early as the early 1900s, this was being proven by a psychologist named Lev Vygotsky. He proposed that children's learning is a social activity, which is achieved by interaction with more skilled members of society. There are many studies, which provide evidence for this claim. there are however, as yet no controlled studies on neuro - cognitive therapy.

Patterning is a controversial form of alternative therapy
Alternative therapy

Alternative therapy may refer to:*Alternative medicine*Alternative therapies for developmental and learning disabilities...
 for people with CP. The method is promoted by The Institutes for the Achievement of Human Potential
The Institutes for The Achievement of Human Potential

The Institutes for The Achievement of Human Potential is a non-profit organization providing teaching programs and literature which, it claims, improve the health and neurological development of normal children and of children who have sustained a brain injury....
 (IAHP), a Philadelphia nonprofit, but has been criticized by the American Academy of Pediatrics
American Academy of Pediatrics

The American Academy of Pediatrics was founded in 1930 and now has 60,000 primary care pediatricians, pediatric medical subspecialists and pediatric surgical specialists as members....
. The IAHP's methods have been endorsed by Linus Pauling
Linus Pauling

Linus Carl Pauling was an United States scientist, peace activist, author and list of educators. He was one of the most influential chemists in history and ranks among the most important scientists in any field of the 20th century....
, as well as some parents of children treated with their methods.

Cultural aspects


Economic Impact Of Cerebral Palsy In Australia

Access Economics has released a report on the economic impact of cerebral palsy in Australia. Launched by the Hon Bill Shorten, MP, the report found that, in 2007, the financial cost of cerebral palsy (CP) in Australia was $1.47 billion or 0.14% of GDP. When the value of lost wellbeing (disability and premature death) was added, the cost rose a further $2.4 billion.

In 2007, the financial cost of CP was $1.47 billion (0.14% of GDP). Of this:

  • 1.03 billion (69.9%) was productivity lost due to lower employment, absenteeism and premature death of Australians with CP;


  • 141 million (9.6%) was the DWL from transfers including welfare payments and taxation forgone;


  • 131 million (9.0%) was other indirect costs such as direct program services, aids and home modifications and the bringing-forward of funeral costs;


  • 129 million (8.8%) was the value of the informal care for people with CP; and


  • 40 million (2.8%) was direct health system expenditure.


Additionally, the value of the lost wellbeing (disability and premature death) was a further $2.4 billion.

In per capita terms, this amounts to a financial cost of $43,431 per person with CP per annum. Including the value of lost wellbeing, the cost is over $115,000 per person per annum.

Individuals with CP bear 37% of the financial costs, and their families and friends bear a further 6%. Federal government bears around one third (33%) of the financial costs (mainly through taxation revenues forgone and welfare payments). State governments bear under 1% of the costs, while employers bear 5% and the rest of society bears the remaining 19%.If the burden of disease (lost wellbeing) is included, individuals bear 76% of the costs.

Read the full report…

Use of terms when referring to people with CP

Many people would rather be referred to as a person with a disability instead of handicapped. "Cerebral Palsy: A Guide for Care" at the University of Delaware
University of Delaware

The University of Delaware is the largest university in the U.S. state of Delaware. The main campus is located in Newark, Delaware, with satellite campuses in Dover, Delaware, Wilmington, Delaware, Lewes, Delaware and Georgetown, Delaware....
 offers the following guidelines:

Impairment is the correct term to use to define a deviation from normal, such as not being able to make a muscle move or not being able to control an unwanted movement. Disability is the term used to define a restriction in the ability to perform a normal activity of daily living which someone of the same age is able to perform. For example, a three year old child who is not able to walk has a disability because normal three year old can walk independently. Handicap is the term used to describe a child or adult who, because of the disability, is unable to achieve the normal role in society commensurate with his age and socio-cultural milieu. As an example, a sixteen-year- old who is unable to prepare his own meal or care for his own toileting or hygiene needs is handicapped. On the other hand, a sixteen-year- old who can walk only with the assistance of crutches but who attends a regular school and is fully independent in activities of daily living is disabled but not handicapped. All disabled people are impaired, and all handicapped people are disabled, but a person can be impaired and not necessarily be disabled, and a person can be disabled without being handicapped.


The term "spastic
Spastic

Evolution of the term in the United KingdomIt is generally regarded as having been brought to public knowledge and popularised from its use in the name of The Spastics Society ]], a charity for people with cerebral palsy, which was founded in 1951 and has a reasonably high public profile from its street collections and charity shops....
" describes the attribute of spasticity in types of spastic CP. In 1952 a UK charity called The Spastics Society was formed. The term "spastics" was used by the charity as a term for people with CP. The word "spaz" has since been used extensively as a general insult to disabled people, which some see as extremely offensive. It is also frequently used to insult able-bodied people when they seem overly anxious or unskilled in sports. The charity changed its name to Scope
Scope (British charity)

Scope is a London-based charitable organization, which operates in England and Wales, focusing on people with cerebral palsy particularly, and disabled people in general....
 in 1994. In the United States the word spaz has the same usage as an insult, but is not generally associated with CP.

Misconceptions

A common misconception about those born with Cerebral Palsy is that they are less intelligent than those born without it. Cerebral Palsy is defined as damage to the part of the brain that controls movement; areas of the brain that define a person's intelligence are not affected by CP.

Spastic Cerebral Palsy, the most common form of CP, causes the muscles to be tense, rigid and movements are slow and difficult. This can be misinterpreted as cognitive delay due to difficulty of communication. Individuals with cerebral palsy can have learning difficulties, but sometimes it is the sheer magnitude of problems caused by the underlying brain injury that prevents the individual from expressing what cognitive abilities they do possess.

Public perception

Those with CP are sometimes stigmatized and shunned. This has lessened since the 1950s thanks to public education and to United Cerebral Palsy
United Cerebral Palsy

United Cerebral Palsy , sometimes known as United Cerebral Palsy Associations, is a network of affiliated groups in the United States which works to "advance the independence, productivity and full citizenship of people with disabilities" , including people with cerebral palsy....
 in the U.S. and similar organizations in other countries. Prior to that time the great majority were often sent to asylums or confined to attics. They were perceived to be the products of incest and partial smothering.

Thomas Galton believed that there was a correlation between physical disability and aptitude, and this attitude remained prevalent as concerned CP until the 1970s.

Only individuals with brain damage in the hippocampus
Hippocampus

The hippocampus is a brain structure located inside the medial temporal lobe of the cerebral cortex, and therefore is part of the telencephalon ....
 or the frontal cerebral cortex
Cerebral cortex

The cerebral cortex is a structure within the brain that plays a key role in memory, attention, perceptual awareness, thought, language, and consciousness....
 develop mental retardation. While learning difficulties and CP may be associated, it is common for individuals with CP to lead normal lives.

Cultural references

  • (1981) In the television series The Facts of Life
    The Facts of Life

    The Facts of Life may refer to:*A euphemism for sexual education, particularly coming from a parent. Similar to the birds and the bees.*The Facts of Life , a U.S....
    , Blair's cousin Geri has CP.


  • (1987) In the William Horwood
    William Horwood (novelist)

    William Horwood is an England novelist. His first novel, Duncton Wood, an allegorical tale about a community of Mole s, was published in 1980....
     novel Skallagrigg
    Skallagrigg

    Skallagrigg is a 1987 novel written by William Horwood .The book was influenced by William Horwood's relationship with his own daughter Rachel, who has cerebral palsy....
    , the central character Esther Marquand has CP.


  • (1989) In the film My Left Foot
    My Left Foot (film)

    My Left Foot: The Story of Christy Brown is a 1989 in film drama film directed by Jim Sheridan and starring Daniel Day-Lewis. It tells the story of Christy Brown, an Ireland born with cerebral palsy, who could only control his left foot....
    , Daniel-Day Lewis plays Christy Brown
    Christy Brown

    Christy Brown was an Irish ethnicity author, Painting and poet who had severe cerebral palsy. He is most famous for his autobiography My Left Foot , which was later made into an Academy Award-winning My Left Foot ....
    , who suffers from CP. He won the Best Lead Actor Award for his performance at the Academy Awards
    Academy Awards

    The Academy Awards, popularly known as the Oscars, are presented annually by the Academy of Motion Picture Arts and Sciences to recognize excellence of professionals in the film industry, including directors, actors, and writers....
     in 1990.


  • (1991) In the book Gridlock
    Gridlock (novel)

    Gridlock is a 1991 in literature novel by Ben Elton....
    , the main character Geoffrey Peason has Spastic Cerebral Palsy.


  • (1995) In the film The Usual Suspects
    The Usual Suspects

    The Usual Suspects is a 1995 Cinema of the United States neo-noir film written by Christopher McQuarrie and directed by Bryan Singer. The film tells the story of Roger "Verbal" Kint , a small-time Confidence trick who is the subject of a police interrogation....
    , Kevin Spacey
    Kevin Spacey

    Kevin Spacey is an American character actor, film director, screenwriter, film producer, and crooner. He grew up in California, and began his career as a stage actor during the 1980s, before being cast in supporting roles in film and television....
     plays Verbal Kint, a criminal who appears to have CP.


  • (2000) The film King Gimp
    King Gimp

    King Gimp is a 1999 in film documentary that was awarded the 2000 Academy Award for Academy Award for Documentary Short Subject and 2000 Peabody Award....
     is a documentary on the life of Dan Keplinger
    Dan Keplinger

    Artist Dan Keplinger was featured in the Academy Awards-winning documentary short, King Gimp. Born January 19, 1973 with cerebral palsy, he lives in Towson, Maryland, where he continues to paint....
     who has CP.


  • (2001) In the film Storytelling
    Storytelling (film)

    Storytelling is a 2001 in film, directed by Todd Solondz. It features original music by Belle & Sebastian, later compiled on an Storytelling ....
    , a love interest of Selma Blair
    Selma Blair

    Selma Blair is an American actress. After numerous supporting roles in the 1990s, she starred in the film Cruel Intentions and the short-lived TV series Zoe, Duncan, Jack and Jane in 1999....
    's character has CP.


  • (2002) The South Korean film Oasis
    Oasis (film)

    Oasis is South Korea Lee Chang-dong's third feature film, and the last one he directed before his stint as South Korea's Minister of Culture....
     follows the unconventional romance between two social outcasts, a marginalized ex-con and a young woman with CP.


  • (2002) In the film Door to Door
    Door to Door (film)

    Door to Door was a 2002 TV movie about Bill Porter , a door-to-door salesman afflicted with cerebral palsy. The film was produced for the Turner Network Television cable television network and was nominated for twelve Emmy Awards, winning six....
     the story is focused around William H. Macy
    William H. Macy

    William Hall Macy, Jr. is an Academy Award-nominated, double Emmy- and Screen Actors Guild Award-winning American actor. He is also a teacher and director in theater, film and television....
     who plays a salesman with CP named Bill Porter
    Bill Porter (salesman)

    Bill Porter is an United States salesman for the Watkins Company. Born with cerebral palsy, Porter became quite well known in 1995, when an Oregon newspaper wrote a series of feature stories about him....
    . This story is based on the real Bill Porter's life.


  • (2002) An Alex Pardee
    Alex Pardee

    Alex Pardee is an artist, best known for illustrating The Used's album artwork. He has also done works for Hurley International, Twenty Twenty Skateboards, Bay Area rapper TopR, Upper Playground, Street Drum Corps, Aiden, Kid Robot, and lately the cover of In Flames's ninth studio album, A Sense of Purpose, and its first single, entitle...
     character in The Used
    The Used (album)

    The Used is the self-titled debut album by The Used. It was released on June 25, 2002 and has since been certified gold. Before this album was released, The Used released an independent demo album in 2001 that fans call Demos from the Basement....
     is Sandy, a prostitute with CP.


  • (2004) The film Inside I'm Dancing
    Inside I'm Dancing

    Inside I'm Dancing, also released under the title Rory O'Shea Was Here, is a 2004 in film Irish film. It was directed by Damien O'Donnell ....
     focuses on a quadriplegic youth in Dublin who befriends someone with CP and acts as his translator.


  • (2005) In the Ricky Gervais
    Ricky Gervais

    Ricky Dene Gervais is an England comedian, author, actor, Television director, Television producer, screenwriter and former pop music musician....
     and Stephen Merchant
    Stephen Merchant

    Stephen James Merchant is a British Comedy Award-, BAFTA-, Emmy- and Golden Globe-award winning United Kingdom writer, director, and comic actor....
     sitcom Extras
    Extras (TV series)

    Extras is a British Academy Television Awards, Golden Globe and Emmy award-winning United Kingdom Situation comedy about Extra working on film sets and in theatre....
    , a series one episode featured main protagonist Andy Millman ridiculing a person with CP (by mistaking her as a drunk); after the character (played by Francesca Martinez
    Francesca Martinez

    Francesca Martinez is an award-winning England stand-up comedian. She has toured internationally including sell-out runs at the Edinburgh Festival, the Melbourne Comedy Festival and the prestigious Just For Laughs Festival in Montreal....
    , who herself suffers from Cerebral Palsy) corrects him, he empathizes with her.


  • (2007) In the film Music Within
    Music Within

    Music Within is a 2007 drama film starring Ron Livingston and Melissa George....
    , Michael Sheen
    Michael Sheen

    Michael Sheen, Order of the British Empire is a BAFTA Award- and Laurence Olivier Award-nominated Wales actor best known for his portrayal of Tony Blair in the Stephen Frears directed films The Deal and The Queen , and for his portrayal of David Frost in both the Frost/Nixon and the film version of Frost/Nixon ....
     plays a character who has Cerebral Palsy.


  • (2008) The TV drama Breaking Bad
    Breaking Bad

    Breaking Bad is an American television drama series created and Executive producer#Television by Vince Gilligan. The series is broadcast in the United States and Canada on the cable network AMC ....
     features the son of the main character as having CP. The actor, RJ Mitte
    RJ Mitte

    RJ Mitte is an United States actor. He is best known for his role as Walter White Jr. on the AMC television series, Breaking Bad.In 2006 RJ Mitte moved to Hollywood and began training with personal talent manager Addison Witt....
    , actually has mild CP, and Breaking Bad is his breakout role.


  • (2008) In the drama series Heroes
    Heroes (TV series)

    Heroes is an American science fiction dramatic programming created by Tim Kring, which premiered on NBC on September 25, 2006. The series tells the stories of ordinary individuals from around the world who inexplicably develop Superpower , and their roles in preventing disasters, usually foreseen in images produced by precognitive painter...
    , Brea Grant
    Brea Grant

    Brea Colleen Grant is an United States actor who is best known for playing Daphne Millbrook in NBC's science fiction television program Heroes ....
     plays Daphne Millbrook, a thief who has CP. The character's disability is not initially apparent, as her ability to move at superhuman speeds negates it.


Notable people

  • Kaine, member of the rap duo Ying Yang Twins
    Ying Yang Twins

    The Ying Yang Twins are an Atlanta, Georgia-based United States crunk hip hop music duo consisting of Kaine and D-Roc . It is unknown why they chose to add a "g" to the end of "Yin", as their name is clearly a derivative of the Chinese philosophy of Yin and Yang....
    .
  • Christy Brown
    Christy Brown

    Christy Brown was an Irish ethnicity author, Painting and poet who had severe cerebral palsy. He is most famous for his autobiography My Left Foot , which was later made into an Academy Award-winning My Left Foot ....
    , Irish writer and painter who wrote My Left Foot
    My Left Foot (book)

    My Left Foot is the 1954 autobiography of Christy Brown, an Irish ethnicity author, Painting and poet who had cerebral palsy.Brown was born in Crumlin, Dublin, Dublin....
    , which was later adapted into an Oscar winning movie of the same name
    My Left Foot (film)

    My Left Foot: The Story of Christy Brown is a 1989 in film drama film directed by Jim Sheridan and starring Daniel Day-Lewis. It tells the story of Christy Brown, an Ireland born with cerebral palsy, who could only control his left foot....
     starring Daniel Day Lewis
  • Eric S. Raymond
    Eric S. Raymond

    Eric Steven Raymond , often referred to as ESR, is a computer programmer, author and open source software advocate. His name became known within the hacker culture when he became the maintainer of the "Jargon File"....
    , an open source
    Open source

    Open source is an approach to design, development, and distribution offering practical accessibility to a product's source . Some consider open source as one of various possible design approaches, while others consider it a critical Strategy element of their business operations....
     computer programmer.
  • Christopher Widdows aka Steady Eddy, Australian comedian
  • Francesca Martinez
    Francesca Martinez

    Francesca Martinez is an award-winning England stand-up comedian. She has toured internationally including sell-out runs at the Edinburgh Festival, the Melbourne Comedy Festival and the prestigious Just For Laughs Festival in Montreal....
    , English stand-up comedian.
  • Joel Gausten
    Joel Gausten

    Joel Gausten is an United States drummer, publisher, author and journalist. He is an alumni of Wallkill Valley Regional High School.A drummer since age 9, Gausten has appeared on over 50 CDs, EPs and internationally distributed compilations with such acts as Electric Frankenstein, the Sixth Chamber, Broken Heroes and the Graveyard School....
    , American journalist, author and musician.
  • Josh Blue
    Josh Blue

    Josh Blue is an United States comedian who was voted the Last Comic Standing on NBC's reality show Last Comic Standing during its Last Comic Standing 4, which aired May–August, 2006....
    , comedian and winner of the fourth season of Last Comic Standing
    Last Comic Standing

    Last Comic Standing is an United States reality television talent show that premiered in 2003. The objective of the program is to select a comedian from a group, who will receive a development contract with the NBC television network and a Television Special first to air on the cable television Comedy Central and later on the cable networ...
    , who often jokes about his condition.
  • Gianna Jessen
    Gianna Jessen

    Gianna Jessen is a Christianity recording artist and pro-life activist....
    , singer-songwriter and pro-life activist
  • Stephen Hopkins
    Stephen Hopkins (politician)

    Stephen Hopkins was an American political leader from Rhode Island who signed the United States Declaration of Independence. He served as the Chief Justice and Governor of colonial Rhode Island and was a Delegate to the Albany Congress in 1754 and to the Continental Congress from 1774 to 1776....
    , signer of USA Declaration of Independence, reputed to have stated, "My hand trembles, but my heart does not."
  • Bill Porter
    Bill Porter (salesman)

    Bill Porter is an United States salesman for the Watkins Company. Born with cerebral palsy, Porter became quite well known in 1995, when an Oregon newspaper wrote a series of feature stories about him....
    , a salesman for Watkins Incorporated
    Watkins Incorporated

    Watkins Incorporated is a manufacturer of health remedies, baking products, and other household items. The entire catalog includes 400 products....
     whose life story was told in the TV movie Door to Door
    Door to Door (film)

    Door to Door was a 2002 TV movie about Bill Porter , a door-to-door salesman afflicted with cerebral palsy. The film was produced for the Turner Network Television cable television network and was nominated for twelve Emmy Awards, winning six....
    .
  • Karen Killilea
    Karen Killilea

    Karen Ann Killilea is the subject of two bestselling books by her mother Marie Killilea, Karen and With Love from Karen. These books were groundbreaking in their assertion that children with cerebral palsy could be raised to lead productive lives....
    , the subject of the book Karen (1952) and its sequel, With Love from Karen (1963), by her mother Marie Killilea.
  • RJ Mitte
    RJ Mitte

    RJ Mitte is an United States actor. He is best known for his role as Walter White Jr. on the AMC television series, Breaking Bad.In 2006 RJ Mitte moved to Hollywood and began training with personal talent manager Addison Witt....
    , American actor known for his role in the critically acclaimed AMC
    AMC (TV network)

    AMC is a cable television network that primarily airs Films. The letters originally stood for American Movie Classics. However, since 2003, the full name has been deemphasized as a result of a major shift in programming....
     series Breaking Bad
    Breaking Bad

    Breaking Bad is an American television drama series created and Executive producer#Television by Vince Gilligan. The series is broadcast in the United States and Canada on the cable network AMC ....
  • Gabriela Brimmer
    Gabriela Brimmer

    Gabriela Brimmer, "Gaby", , a writer and activist for persons with disabilities, was born in Mexico as a daughter of Austrian Jewish immigrants....
    , poet and disability rights activist
  • Geri Jewell
    Geri Jewell

    Geri Jewell is an actor and comedian born with cerebral palsy.She is most famous for her roles on the television program The Facts of Life and on HBO's Deadwood ....
    , actress and comedienne best known for her roles on the TV series The Facts of Life and later Deadwood
  • Cara Readle
    Cara Readle

    Cara Readle is a young disabled British actress known mainly for her role in The Story of Tracy Beaker as Layla from series three to five....
    , young actress known for her role as Layla on CBBC's Tracy Beaker
    The Story of Tracy Beaker (TV series)

    'The Story of Tracy Beaker' was a TV show adapted from The Story of Tracy Beaker by Jacqueline Wilson. It ran on CBBC for five series, from 2002 to 2005, and a feature length episode, Tracy Beaker's Movie of Me, was broadcast in 2004, as well as a week of interactive episodes for Children in Need, entitled Tracy Beaker Parties with Pu...
  • Paul Henshall
    Paul Henshall

    Paul Henshall is a United Kingdom actor. He uses a wheelchair because he has cerebral palsy.Paul is most famous for playing the role of medical student Dean West in Holby City, and of Paul in I'm With Stupid ....
    , British TV actor
  • Ruben Gallego
    Ruben Gallego

    Ruben David Gonzalez Gallego was born in Moscow, Russia, with severe cerebral palsy.Gallego was separated from his family at the age of one; he was sent to a state orphanage, because his grandfather, Ignacio Gallego, who was Secretary-General of the Spanish Communist Party, was ashamed of him and told his daughter that her son had died....
    , writer of White on Black: A Boy's Story, a memoir book on his early life in Russian institutes.
  • David Ring
    David Ring

    David Ring is a Christian Evangelism and motivational speaker who suffers from cerebral palsy. Since 1973, Ring has challenged thousands of people with his signature message - "I have cerebral palsy......
    , American Christian evangelist and motivational speaker
  • Emperor Claudius, the Roman Emperor who was also a stutterer and walked with a limp is believed to have had CP.
  • Susie Maroney
    Susie Maroney

    Susie Maroney , was an Australian marathon swimmer. She was four years old when she started swimming.She was born with cerebral palsy. She initially kept her condition secret but in 2007 she sold her story to the TV talk show Enough Rope....
    , world-record holding marathon swimmer.
  • Baruch Kimmerling
    Baruch Kimmerling

    Baruch Kimmerling was a professor of sociology at the Hebrew University of Jerusalem....
    , Israeli sociologist and political dissident
  • Greg Walloch
    Greg Walloch

    Greg Walloch is an American comedian, actor, author, and monologist.Walloch is best known for his autobiographical performance monologues, which deal with events from his own life, in a style characterized by humor, poignancy, and Sex....
    , American writer, actor and comedian
  • Joey Deacon
    Joey Deacon

    Joseph John "Joey" Deacon was a England author and television personality....
    , British author and television personality
  • Eric Gores
    Eric Gores

    Eric Gores is the son of billionaire Alec Gores and former neighbor of actor Tom Arnold . In 2005, Gores costarred in a film written by Arnold, The Kid & I....
    , American actor who starred in The Kid & I
    The Kid & I

    The Kid & I is a 2005 in film comedy film film starring Tom Arnold and Eric Gores....
  • Maysoon Zayid, Palestinian-American actor and comedienne.
  • Christopher Nolan
    Christopher Nolan (author)

    Christopher Nolan was an Ireland poet and author, son of Joseph and Bernadette Nolan. He grew up in Mullingar, Ireland, but later moved to Dublin to attend college....
    , Irish poet and author, died on Feb 20, 2009, after choking on food.


External links

  • : Help in the US
  • : One of the biggest CP communities on the internet with information and support for families.
  • : Empowering Families Through Education