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Calcification
 
 
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Calcification is the process in which the mineral calcium builds up in soft tissue, causing it to harden. Calcifications may be classified on whether there is mineral balance or not, and the location of the calcification.











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Calcification is the process in which the mineral calcium builds up in soft tissue, causing it to harden. Calcifications may be classified on whether there is mineral balance or not, and the location of the calcification.

Mineral balance

  • Dystrophic calcification
    Dystrophic calcification

    Dystrophic Calcification is the calcification occurring in degenerated or necrotic tissue, as in hyalinized scars, degenerated foci in leiomyomas, and caseous nodules....
    , without a systemic
    Systemic circulation

    Systemic circulation is the portion of the cardiovascular system which carries oxygenated blood away from the heart, to the body, and returns deoxygenated blood back to the heart....
     mineral imbalance.
  • Metastatic calcification
    Metastatic calcification

    Metastatic calcification is deposition of calcium salts in otherwise normal tissue, because of elevated serum levels of calcium in blood, which can occur because of deranged metabolism, synthesis or disposal of Calcium metabolism and related minerals....
    , a systemic elevation calcium levels in the blood and all tissues.


Location

  • Skeletal calcification
  • Extraskeletal calcification
    • e.g. calciphylaxis
      Calciphylaxis

      Calciphylaxis is a syndrome of vascular calcification, thrombosis and skin necrosis. It is seen almost exclusively in patients with Stage 5 chronic kidney disease....


See also

  • Monckeberg's arteriosclerosis
    Monckeberg's arteriosclerosis

    Monckeberg's arteriosclerosis, also called medial calcific sclerosis, is a form of arteriosclerosis or vessel hardening, where calcium deposits form in the middle layer of the walls of medium sized vessels ....