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CD19
 
 
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CD19 (Cluster of Differentiation 19), is a human protein
Protein

Proteins are organic compounds made of amino acids arranged in a linear chain and joined together by peptide bonds between the carboxyl and amino groups of adjacent amino acid Residue ....
 encoded by the gene
Gene

A gene is the basic unit of heredity in a living organism. All living things depend on genes. Genes hold the information to build and maintain their cell and pass genetic trait to offspring....
.

CD19 is expressed on follicular dendritic cells
Follicular dendritic cells

Follicular dendritic cells are cells of the immune system found in lymph follicles. They are probably not of hematopoietic origin, but simply look similar to true dendritic cells....
 and B cells. In fact, it is present on B cells from earliest recognizable B-lineage cells during development to B-cell blasts but is lost on maturation to plasma cells.

It primarily acts as a B cell co-receptor in conjunction with CD21 and CD81
CD81

CD81 molecule, also known as CD81 , is a human gene....
.

Upon activation, the cytoplasmic tail of CD19 becomes phosphorylated which leads to binding by Src
SRC

SRC may refer to:...
-family kinases and recruitment of PI-3 kinase.








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Encyclopedia


CD19 (Cluster of Differentiation 19), is a human protein
Protein

Proteins are organic compounds made of amino acids arranged in a linear chain and joined together by peptide bonds between the carboxyl and amino groups of adjacent amino acid Residue ....
 encoded by the gene
Gene

A gene is the basic unit of heredity in a living organism. All living things depend on genes. Genes hold the information to build and maintain their cell and pass genetic trait to offspring....
.

CD19 is expressed on follicular dendritic cells
Follicular dendritic cells

Follicular dendritic cells are cells of the immune system found in lymph follicles. They are probably not of hematopoietic origin, but simply look similar to true dendritic cells....
 and B cells. In fact, it is present on B cells from earliest recognizable B-lineage cells during development to B-cell blasts but is lost on maturation to plasma cells.

It primarily acts as a B cell co-receptor in conjunction with CD21 and CD81
CD81

CD81 molecule, also known as CD81 , is a human gene....
.

Upon activation, the cytoplasmic tail of CD19 becomes phosphorylated which leads to binding by Src
SRC

SRC may refer to:...
-family kinases and recruitment of PI-3 kinase.

Further reading