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CAP (protein)

CAP (protein)

Overview
Adenylate Cyclase Associated Protein is an actin-binding protein
Actin-binding protein
Actin-binding proteins are proteins that bind to actin. This may mean ability to bind actin monomers, or polymers, or both....

 that was originally identified as a binding partner for adenylate cyclase
Adenylate cyclase
Adenylate cyclase is a lyase enzyme. It is a part of the cAMP-dependent pathway-Types:There are ten known adenylate cyclases in mammals:* ADCY1* ADCY2* ADCY3* ADCY4* ADCY5...

. It binds actin
Actin
Actin is a globular, roughly 42-kDa protein found in all eukaryotic cells where it may be present at concentrations of over 100 μM. It is also one of the most highly-conserved proteins, differing by no more than 20% in species as diverse as algae and humans...

 monomers and sequesters them from the polymerization process. The yeast
Yeast
Yeasts are eukaryotic micro-organisms classified in the kingdom Fungi, with about 1,500 species currently described; they dominate fungal diversity in the oceans. Most reproduce asexually by budding, although a few do so by binary fission...

 ortholog of CAP is called Srv2.
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Encyclopedia
Adenylate Cyclase Associated Protein is an actin-binding protein
Actin-binding protein
Actin-binding proteins are proteins that bind to actin. This may mean ability to bind actin monomers, or polymers, or both....

 that was originally identified as a binding partner for adenylate cyclase
Adenylate cyclase
Adenylate cyclase is a lyase enzyme. It is a part of the cAMP-dependent pathway-Types:There are ten known adenylate cyclases in mammals:* ADCY1* ADCY2* ADCY3* ADCY4* ADCY5...

. It binds actin
Actin
Actin is a globular, roughly 42-kDa protein found in all eukaryotic cells where it may be present at concentrations of over 100 μM. It is also one of the most highly-conserved proteins, differing by no more than 20% in species as diverse as algae and humans...

 monomers and sequesters them from the polymerization process. The yeast
Yeast
Yeasts are eukaryotic micro-organisms classified in the kingdom Fungi, with about 1,500 species currently described; they dominate fungal diversity in the oceans. Most reproduce asexually by budding, although a few do so by binary fission...

 ortholog of CAP is called Srv2.