Basket cells are inhibitory GABA

Gabâ

Gabâ or gabaa, for the people in many parts of the Philippines), is the concept of a non-human and non-divine, imminent retribution. A sort of negative karma, it is generally seen as an evil effect on a person because of their wrongdoings or transgressions...

ergic interneurons found in several brain regions: the molecular layer  of the cerebellum

Cerebellum

The cerebellum is a region of the brain that plays an important role in motor control. It may also be involved in some cognitive functions such as attention and language, and in regulating fear and pleasure responses, but its movement-related functions are the most solidly established...

, the hippocampus

Hippocampus

The hippocampus is a major component of the brains of humans and other vertebrates. It belongs to the limbic system and plays important roles in the consolidation of information from short-term memory to long-term memory and spatial navigation. Humans and other mammals have two hippocampi, one in...

, and the cortex

Cerebral cortex

The cerebral cortex is a sheet of neural tissue that is outermost to the cerebrum of the mammalian brain. It plays a key role in memory, attention, perceptual awareness, thought, language, and consciousness. It is constituted of up to six horizontal layers, each of which has a different...

.

Cerebellum

In the cerebellum, they synapse on the cell bodies of Purkinje cell

Purkinje cell

For the cells of the electrical conduction system of the heart, see Purkinje fibersPurkinje cells, or Purkinje neurons , are a class of GABAergic neurons located in the cerebellar cortex...

s, and are multipolar and stellate, with freely branching dendrite

Dendrite

Dendrites are the branched projections of a neuron that act to conduct the electrochemical stimulation received from other neural cells to the cell body, or soma, of the neuron from which the dendrites project...

s, which are dilated and knotty.

Hippocampus

Hippocampal basket cells target somata and proximal dendrite

Dendrite

Dendrites are the branched projections of a neuron that act to conduct the electrochemical stimulation received from other neural cells to the cell body, or soma, of the neuron from which the dendrites project...

s of pyramidal neurons. Cortical and hippocampal basket cells are parvalbumin

Parvalbumin

Parvalbumin is a calcium-binding albumin protein with low molecular weight .It has three EF hand motifs and is structurally related to calmodulin and troponin C...

-expressing and fast-spiking

Action potential

In physiology, an action potential is a short-lasting event in which the electrical membrane potential of a cell rapidly rises and falls, following a consistent trajectory. Action potentials occur in several types of animal cells, called excitable cells, which include neurons, muscle cells, and...

.

Cortex

In the cortex, basket cells have sparsely branched axons giving off small pericellular, basket-shaped elaborations at several intervals along their length. There are three types of basket cells in the cortex, the small, large and nest type: The axon of a small basket cell arborizes in the vicinity of that same cells dendritic range. In contrast, large basket cells innervate somata in different cortical columns. The nest basket cells are an intermediate form of the small and large cells, their axons are confined mainly to the same cortical layer as their somata.

External links

• Cell Centered Database - Cerebellar basket cell
• NIF Search - Basket Cell via the Neuroscience Information Framework
  Neuroscience Information Framework
  The Neuroscience Information Framework is a repository of global neuroscience web resources, including experimental, clinical, and translational neuroscience databases, knowledge bases, atlases, and genetic/genomic resources.-Description:...