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Antipokhmelin
 
 
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Antipokhmelin is a Russia
Russia

Russia , or the Russian Federation , is a list of countries spanning more than one continent country extending over much of northern Eurasia....
n tablet that helps to prevent or overcome the negative effects of alcohol consumption and hangover
Hangover

A hangover describes the sum of unpleasant physiological effects following heavy consumption of drugs, particularly alcoholic beverages. The most commonly reported characteristics of a hangover include headache, nausea, sensitivity to photophobia and phonophobia, lethargy, dysphoria, and thirst....
. The main ingredient is succinic acid
Succinic acid

Succinic acid is a dicarboxylic acid. Succinate plays a biochemical role in the citric acid cycle....
, also found in amber
Amber

Amber is fossil tree resin, which is appreciated for its color and beauty. Good quality amber is used for the manufacture of ornamental objects and jewelry....
. It is marketed as RU-21 in the US and UK. Claims of effectiveness are based primarily on anecdotal evidence
Anecdotal evidence

The expression anecdotal evidence has two distinct meanings. Evidence in the form of an anecdote or hearsay is called anecdotal if there is doubt about its veracity: the evidence itself is considered untrustworthy or untrue....
, and there have been no known placebo
Placebo

The placebo effect is a phenomenon in medicine where the results of a medical treatment are affected by their symbolism, and not just their medical value....
 controlled double blind studies published in peer review
Peer review

Peer review is the process of subjecting an author's Scholarly method work, research, or ideas to the scrutiny of others who are experts in the same field....
ed scientific journal
Scientific journal

In academic publishing, a scientific journal is a periodical publication intended to further the progress of science, usually by reporting new research....
s.

RU-21 was developed by Prof. Eugene Mayevski at the Institute of Theoretical and Experimental Biophysics (division of the Russian Academy of Sciences), where the product was also clinically tested.






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Antipokhmelin is a Russia
Russia

Russia , or the Russian Federation , is a list of countries spanning more than one continent country extending over much of northern Eurasia....
n tablet that helps to prevent or overcome the negative effects of alcohol consumption and hangover
Hangover

A hangover describes the sum of unpleasant physiological effects following heavy consumption of drugs, particularly alcoholic beverages. The most commonly reported characteristics of a hangover include headache, nausea, sensitivity to photophobia and phonophobia, lethargy, dysphoria, and thirst....
. The main ingredient is succinic acid
Succinic acid

Succinic acid is a dicarboxylic acid. Succinate plays a biochemical role in the citric acid cycle....
, also found in amber
Amber

Amber is fossil tree resin, which is appreciated for its color and beauty. Good quality amber is used for the manufacture of ornamental objects and jewelry....
. It is marketed as RU-21 in the US and UK. Claims of effectiveness are based primarily on anecdotal evidence
Anecdotal evidence

The expression anecdotal evidence has two distinct meanings. Evidence in the form of an anecdote or hearsay is called anecdotal if there is doubt about its veracity: the evidence itself is considered untrustworthy or untrue....
, and there have been no known placebo
Placebo

The placebo effect is a phenomenon in medicine where the results of a medical treatment are affected by their symbolism, and not just their medical value....
 controlled double blind studies published in peer review
Peer review

Peer review is the process of subjecting an author's Scholarly method work, research, or ideas to the scrutiny of others who are experts in the same field....
ed scientific journal
Scientific journal

In academic publishing, a scientific journal is a periodical publication intended to further the progress of science, usually by reporting new research....
s.

RU-21 was developed by Prof. Eugene Mayevski at the Institute of Theoretical and Experimental Biophysics (division of the Russian Academy of Sciences), where the product was also clinically tested. Further tests were conducted at the Russian Ministry of Public Health. The tests confirmed the effects of RU-21 on the body's ability to metabolize alcohol. The legend behind the product's history attributes the development of RU-21 to the KGB
KGB

KGB is the Russian language abbreviation of Committee for State Security , which was the official name of the umbrella organization serving as the Soviet Union's premier security agency, secret police, and intelligence agency, from 1954 to 1991....
. An urban legend
Urban legend

An urban legend, urban myth, or urban tale is a form of modern folklore consisting of stories thought to be factual by those circulating them....
 surrounding RU-21 is that KGB
KGB

KGB is the Russian language abbreviation of Committee for State Security , which was the official name of the umbrella organization serving as the Soviet Union's premier security agency, secret police, and intelligence agency, from 1954 to 1991....
 operatives sought a chemical compound that would allow them to drink heavily with suspected Western intelligence agents, in the Soviet Union
Soviet Union

The Union of Soviet Socialist Republics was a Constitution of the Soviet Union socialist state that existed in Eurasia from 1922 to 1991.The name is a translation of the , romanization of Russian Soyuz Sovetskikh Sotsialisticheskikh Respublik, abbreviated ????, SSSR....
 or the West, and not get drunk. At the same time, according to the legend, the Western agent would become intoxicated and (hopefully) reveal secrets to the KGB agent, who would simply be pretending to be drunk and in fact be perfectly lucid. The legend states that while this did not work, KGB agents discovered that the tablet did have an unpredicted side-effect; the apparent ability to lessen a hangover
Hangover

A hangover describes the sum of unpleasant physiological effects following heavy consumption of drugs, particularly alcoholic beverages. The most commonly reported characteristics of a hangover include headache, nausea, sensitivity to photophobia and phonophobia, lethargy, dysphoria, and thirst....
. While there is some truth to this legend (the KGB did conduct some alcohol-related tests involving key ingredients in RU-21, most notably the succinic acid), KGB has no role in commercializing this product.

After its successful launch in the USA, RU-21 quickly gained international distribution and became somewhat of a cultural phenomenon. While there were no articles published in peer-reviewed journals, RU-21 has achieved recognition among consumers through word-of-mouth and also through strong endorsements from publications, such as GQ, Rolling Stone and NY Post.