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Angiogram

 
Angiogram

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Angiogram



 
 
Angiography or arteriography is a medical imaging
Medical imaging

Medical imaging refers to the techniques and processes used to create s of the human body for clinical purposes or medical science .As a discipline and in its widest sense, it is part of biological imaging and incorporates radiology , radiological sciences, endoscopy, thermography, medical photography and microscopy ....
 technique used to visualize the inside, or lumen
Lumen (anatomy)

A lumen in biology is the inside space of a tubular structure, such as an artery or intestine. By extension, a lumen can also be the inside space of a cellular component or structure, such as the endoplasmic reticulum....
, of blood vessels and organs of the body, with particular interest in the arteries
Artery

Arteries are blood vessels that carry blood away from the heart. All arteries, with the exception of the pulmonary and umbilical arteries, carry oxygenated blood....
, vein
Vein

In the circulatory system, veins are blood vessels that carry blood toward the heart. Most veins carry deoxygenated blood from the tissues back to the heart; exceptions are the pulmonary vein and umbilical veins, both of which carry oxygenated blood....
s and the heart chamber
Heart chamber

Heart chamber is a general term used to refer to any of the four wiktionary:chamber of the mammalian heart :*Right atrium : receives oxygen-depleted blood from the body via the superior vena cava and the inferior vena cava and pumps it through the tricuspid valve into the right ventricle....
s. This is traditionally done by injecting a radio-opaque contrast agent
Radiocontrast

Radiocontrast agents are a type of medical contrast medium used to improve the visibility of internal bodily structures in an X-ray based imaging techniques such as Computed tomography or Radiography ....
 into the blood vessel and imaging using X-ray
X-ray

X-radiation is a form of electromagnetic radiation. X-rays have a wavelength in the range of 10 to 0.01 nanometers, corresponding to frequency in the range 30 Hertz to 30 Hertz and energies in the range 120 Electron volt to 120 keV....
 based techniques such as fluoroscopy
Fluoroscopy

Fluoroscopy is an imaging technique commonly used by physicians to obtain real-time moving images of the internal structures of a patient through the use of a fluoroscope....
. The word itself comes from the Greek
Greek language

Greek is an Indo-European languages native to the southern Balkan peninsula, the language of the Greek people. It forms an independent branch within Indo-European....
 words angeion, "vessel", and graphein, "to write or record".






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Angiography or arteriography is a medical imaging
Medical imaging

Medical imaging refers to the techniques and processes used to create s of the human body for clinical purposes or medical science .As a discipline and in its widest sense, it is part of biological imaging and incorporates radiology , radiological sciences, endoscopy, thermography, medical photography and microscopy ....
 technique used to visualize the inside, or lumen
Lumen (anatomy)

A lumen in biology is the inside space of a tubular structure, such as an artery or intestine. By extension, a lumen can also be the inside space of a cellular component or structure, such as the endoplasmic reticulum....
, of blood vessels and organs of the body, with particular interest in the arteries
Artery

Arteries are blood vessels that carry blood away from the heart. All arteries, with the exception of the pulmonary and umbilical arteries, carry oxygenated blood....
, vein
Vein

In the circulatory system, veins are blood vessels that carry blood toward the heart. Most veins carry deoxygenated blood from the tissues back to the heart; exceptions are the pulmonary vein and umbilical veins, both of which carry oxygenated blood....
s and the heart chamber
Heart chamber

Heart chamber is a general term used to refer to any of the four wiktionary:chamber of the mammalian heart :*Right atrium : receives oxygen-depleted blood from the body via the superior vena cava and the inferior vena cava and pumps it through the tricuspid valve into the right ventricle....
s. This is traditionally done by injecting a radio-opaque contrast agent
Radiocontrast

Radiocontrast agents are a type of medical contrast medium used to improve the visibility of internal bodily structures in an X-ray based imaging techniques such as Computed tomography or Radiography ....
 into the blood vessel and imaging using X-ray
X-ray

X-radiation is a form of electromagnetic radiation. X-rays have a wavelength in the range of 10 to 0.01 nanometers, corresponding to frequency in the range 30 Hertz to 30 Hertz and energies in the range 120 Electron volt to 120 keV....
 based techniques such as fluoroscopy
Fluoroscopy

Fluoroscopy is an imaging technique commonly used by physicians to obtain real-time moving images of the internal structures of a patient through the use of a fluoroscope....
. The word itself comes from the Greek
Greek language

Greek is an Indo-European languages native to the southern Balkan peninsula, the language of the Greek people. It forms an independent branch within Indo-European....
 words angeion, "vessel", and graphein, "to write or record". The film or image of the blood vessel
Blood vessel

The blood vessels are the part of the circulatory system that transport blood throughout the body. There are three major types of blood vessels: the artery, which carry the blood away from the heart, the capillary, which enable the actual exchange of water and chemicals between the blood and the tissues; and the veins, which carry blood from...
s is called an angiograph, or more commonly, an angiogram.

Although the term angiography is strictly defined as based on projectional radiography
Projectional radiography

Projectional radiography or plain film radiography is the practise of producing 2D X-ray images. Typically most body parts being x-rayed, have two 'projections' taken, usually at right angles to each other....
, the term has been applied to newer vascular imaging techniques such as CT angiography
Computed tomography angiography

Computed tomography angiography is a computed tomography technique used to visualize arterial and venous vessels throughout the body. This ranges from arteries serving the brain to those bringing blood to the lungs, kidneys, arms and legs....
 and MR angiography
Magnetic Resonance Angiography

File:Mra-mip.jpgMagnetic Resonance Angiography are a group of techniques based on Magnetic Resonance Imaging to image blood vessels. Magnetic Resonance Angiography is used to generate images of the arteries in order to evaluate them for stenosis , occlusion or aneurysms ....
.

History

The technique was first developed in 1927 by Portuguese
Portugal

Portugal , officially the Portuguese Republic , is a country on the Iberian Peninsula. Located in southwestern Europe, Portugal is the westernmost country of mainland Europe and is bordered by the Atlantic Ocean to the west and south and by Spain to the north and east....
 physician and neurologist Egas Moniz
Egas Moniz

Ant?nio Caetano de Abreu Freire Egas Moniz was a Portugal neurologist. He was the first Portuguese to receive a Nobel Prize in Physiology or Medicine, "for his discovery of the therapeutic value of leucotomy in certain psychoses." He was also one of the earliest developers of the cerebral angiography, the technique of using x-rays to visual...
 to provide contrasted x-ray cerebral angiography
Cerebral angiography

Cerebral angiography is a form of angiography that visualizes the artery and vein supply of the brain. This medical imaging technique was pioneered by Dr....
 in order to diagnose several kinds of nervous diseases, such as tumors and arteriovenous malformations. He is usually recognized as one of the pioneers in this field and was awarded the Nobel Prize
Nobel Prize

The Nobel Prize , established in the 1895 will of Swedish chemist Alfred Nobel; it was first awarded in Nobel Prize in Physics, Nobel Prize in Chemistry, Nobel Prize in Physiology or Medicine, Nobel Prize in Literature, and Nobel Peace Prize in 1901....
 in 1949 as a result of this work. With the introduction of the Seldinger technique
Seldinger technique

The Seldinger technique is a medical procedure to obtain safe access to blood vessels and other hollow organ s. It is eponym Dr. Sven-Ivar Seldinger , a Sweden radiology from Mora Municipality, Sweden, Dalarna County, who introduced the procedure in 1953....
 in 1953, the procedure became markedly safer as no sharp introductory devices needed to remain inside the vascular lumen.

Technique

Angiogram Who 933
Depending on the type of angiogram, access to the blood vessels is gained most commonly through the femoral artery
Femoral artery

The femoral artery is a large artery in the muscles of the thigh....
, to look at the left side of the heart and the arterial system
Artery

Arteries are blood vessels that carry blood away from the heart. All arteries, with the exception of the pulmonary and umbilical arteries, carry oxygenated blood....
 or the jugular or femoral vein
Femoral vein

In the human body, the femoral vein is a blood vessel that accompanies the femoral artery artery in the femoral sheath. It begins at the adductor canal and is a continuation of the popliteal vein....
, to look at the right side of the heart and the venous system. Using a system of guide wire
Guide wire

A guide wire may refer to:*A step in the Seldinger technique*A misspelling of guy-wire...
s and catheters, a type of contrast agent (which shows up by absorbing the x-rays), is added to the blood to make it visible on the x-ray images.

The X-ray
X-ray

X-radiation is a form of electromagnetic radiation. X-rays have a wavelength in the range of 10 to 0.01 nanometers, corresponding to frequency in the range 30 Hertz to 30 Hertz and energies in the range 120 Electron volt to 120 keV....
 images taken may either be still images, displayed on a image intensifier
Image intensifier

Image Intensifier Tube A vacuum tube device for increasing the intensity of available light in an optical system to allow use under low light conditions such as as night, to facilitate visual imaging of low-light processes such as flourescence of materials to X-rays or Gamma rays, or for conversion of non-visible light sources to visible ...
 or film, or motion images. For all structures except the heart, the images are usually taken using a technique called digital subtraction angiography
Digital subtraction angiography

Digital Subtraction Angiography is a type of fluoroscopy technique used in interventional radiology to clearly visualize blood vessels in a bony or dense soft tissue environment....
 (DSA). Images in this case are usually taken at 2 - 3 frames per second, which allows the radiologist to evaluate the flow of the blood through a vessel or vessels. This technique "subtracts" the bones and other organs so only the vessels filled with contrast agent can be seen. The heart images are taken at 15-30 frames per second, not using a subtraction technique. Because DSA requires the patient to remain motionless, it cannot be used on the heart. Both these techniques enable the radiologist or cardiologist to see stenosis
Stenosis

A stenosis is an abnormal narrowing in a blood vessel or other tubular Organ or structure.It is also sometimes called a "stricture" .The term "coarctation" is synonymous, but is commonly used only in the context of aortic coarctation....
 (blockages or narrowings) inside the vessel which may be inhibiting the flow of blood and causing pain.

Uses


Coronary Angiography

One of most common angiograms performed is to visualize the blood in the coronary arteries. A long, thin, flexible tube called a catheter
Catheter

In medicine a catheter is a tubing that can be inserted into a body cavity, duct or vessel. Catheters thereby allow drainage or injection of fluids or access by surgical instruments....
 is used to administer the x-ray contrast agent at the desired area to be visualized. The catheter is threaded into an artery in the groin
Groin

In human anatomy, the groin areas are the two wikt:crease at the junction of the torso with the legs, on either side of the pubic area. A pulled groin muscle usually refers to a pulled Adductor muscles of the hip....
 or forearm
Forearm

The forearm is the structure on the upper limb, between the Elbow-joint and the wrist.. This term is used in anatomy to distinguish it from the arm ....
, and the tip is advanced through the arterial system into one of the two major coronary arteries. X-ray
X-ray

X-radiation is a form of electromagnetic radiation. X-rays have a wavelength in the range of 10 to 0.01 nanometers, corresponding to frequency in the range 30 Hertz to 30 Hertz and energies in the range 120 Electron volt to 120 keV....
 images of the transient radiocontrast
Radiocontrast

Radiocontrast agents are a type of medical contrast medium used to improve the visibility of internal bodily structures in an X-ray based imaging techniques such as Computed tomography or Radiography ....
 distribution within the blood flowing within the coronary arteries allows visualization of the size of the artery openings
Lumen (anatomy)

A lumen in biology is the inside space of a tubular structure, such as an artery or intestine. By extension, a lumen can also be the inside space of a cellular component or structure, such as the endoplasmic reticulum....
. Presence or absence of atherosclerosis
Atherosclerosis

Atherosclerosis is a syndrome affecting artery blood vessels. It is a chronic inflammatory response in the walls of arteries, in large part due to the accumulation of macrophage white blood cells and promoted by low density lipoproteins without adequate removal of fats and cholesterol from the macrophages by functional high density lipoprot...
 or atheroma
Atheroma

In pathology, an atheroma is an accumulation and swelling in artery walls that is made up of cells , or cell debris, that contain lipids , calcium and a variable amount of fibrous connective tissue....
 within the walls of the arteries
Artery

Arteries are blood vessels that carry blood away from the heart. All arteries, with the exception of the pulmonary and umbilical arteries, carry oxygenated blood....
 cannot be clearly determined. See coronary catheterization
Coronary catheterization

A coronary catheterization is a minimally invasive procedure to access the coronary circulation and blood filled chambers of the heart using a catheter....
 for more detail..

Neuro-vascular angiography

Another increasingly common angiographic procedure is neuro-vascular digital subtraction angiography
Digital subtraction angiography

Digital Subtraction Angiography is a type of fluoroscopy technique used in interventional radiology to clearly visualize blood vessels in a bony or dense soft tissue environment....
 in order to visualise the arterial and venous supply to the brain. Intervention work such as coil-embolisation of aneurysm
Aneurysm

An aneurysm is a localized, blood-filled dilation of a blood vessel caused by disease or weakening of the vessel wall.Aneurysms most commonly occur in artery at the base of the brain and in the aorta ....
s and AVM
Arteriovenous malformation

Arteriovenous malformation or AVM in the majority of cases is a congenital disorder consisting of a connection between veins and arteries, this pathology is universally known because of its occurrence in the central nervous system, but can appear in any location....
 gluing can also be performed

Peripheral Angiography

Angiography is also commonly performed to identify vessel narrowing
Stenosis

A stenosis is an abnormal narrowing in a blood vessel or other tubular Organ or structure.It is also sometimes called a "stricture" .The term "coarctation" is synonymous, but is commonly used only in the context of aortic coarctation....
 in patients with leg claudication or cramps, caused by reduced blood flow down the legs and to the feet; in patients with renal stenosis (which commonly causes high blood pressure) and can be used in the head to find and repair stroke. These are all done routinely through the femoral artery, but can also be performed through the brachial or axillary (arm) artery. Any stenoses found may be treated by the use of angioplasty.

Other

Other angiographic uses include the diagnosis of retina
Retina

The vertebrate retina is a light sensitive tissue lining the inner surface of the eye. The optics of the eye create an image of the visual world on the retina, which serves much the same function as the film in a camera....
l vascular disorders, such as diabetic retinopathy
Diabetic retinopathy

Diabetic retinopathy is retinopathy caused by complications of diabetes mellitus, which can eventually lead to blindness.It is an ocular manifestation of systemic disease which affects up to 80% of all patients who have had diabetes for 10 years or more....
 and macular degeneration
Macular degeneration

File:Human eye cross-sectional view grayscale.pngFile:Human eyesight two children and ball normal vision.jpgFile:Human eyesight two children and ball with age-related macular degeneration.jpg...
.

See also

  • Cardiac catheterization
    Cardiac catheterization

    Cardiac catheterization is the insertion of a catheter into a heart chamber or Blood vessel of the heart. This is done for both investigational and interventional purposes....
  • Computed Tomography Angiography
    Computed tomography angiography

    Computed tomography angiography is a computed tomography technique used to visualize arterial and venous vessels throughout the body. This ranges from arteries serving the brain to those bringing blood to the lungs, kidneys, arms and legs....
  • Contrast Medium
    Contrast medium

    A medical contrast medium is a substance used to enhance the contrast of structures or fluids within the body in medical imaging. It is commonly used to enhance the visibility of blood vessels and the gastrointestinal tract....
  • Echocardiogram
  • Electrocardiogram
    Electrocardiogram

    An electrocardiogram is a recording of the electricity activity of the heart over time produced by an electrocardiograph, usually in a Non-invasive recording via skin electrodes....
  • Image intensifier
    Image intensifier

    Image Intensifier Tube A vacuum tube device for increasing the intensity of available light in an optical system to allow use under low light conditions such as as night, to facilitate visual imaging of low-light processes such as flourescence of materials to X-rays or Gamma rays, or for conversion of non-visible light sources to visible ...
  • Intravenous digital subtraction angiography
    Intravenous digital subtraction angiography

    Intravenous digital subtraction angiography is a form of angiography which was first developed in the late 1970s.IV-DSA uses a computer technique which compares an x-ray image of a region of the body before and after radiopaque iodine based dye has been injected Intravenous therapy into the body....
  • Peripheral artery occlusive disease
    Peripheral artery occlusive disease

    Peripheral vascular disease , also known as peripheral artery disease or peripheral artery occlusive disease , includes all diseases caused by the obstruction of large artery in the arms and legs....


External links

  • - The radiology information resource for Cardiologists, Radiologists, Cardiac and Radiologic Techs - A Free Resource For Cardiac Imaging
  • - The radiology information resource for patients: Angiography procedures
  • from Angioplasty.Org
  • from Siemens Medical