André Michel Lwoff
Encyclopedia
André Michel Lwoff was a French
France
The French Republic , The French Republic , The French Republic , (commonly known as France , is a unitary semi-presidential republic in Western Europe with several overseas territories and islands located on other continents and in the Indian, Pacific, and Atlantic oceans. Metropolitan France...

 microbiologist
Microbiologist
A microbiologist is a scientist who works in the field of microbiology. Microbiologists study organisms called microbes. Microbes can take the form of bacteria, viruses, fungi, and protists...

. He was born in Ainay-le-Château
Ainay-le-Château
Ainay-le-Château is a commune in the Allier department in central France. It was an entirely fortified small town during the Middle Ages and some of the old ramparts as well as the medieval church are still well preserved.-Population:-References:*...

, Allier
Allier
Allier is a department in central France named after the river Allier.- History :Allier is one of the original 83 departments created during the French Revolution on 4 March 1790. It was created from parts of the former provinces of Auvergne and Bourbonnais.In 1940, the government of Marshal...

, in Auvergne
Auvergne (région)
Auvergne is one of the 27 administrative regions of France. It comprises the 4 departments of Allier, Puy de Dome, Cantal and Haute Loire.The current administrative region of Auvergne is larger than the historical province of Auvergne, and includes provinces and areas that historically were not...

, France. He joined the Institute Pasteur in Paris when he was 19 years old. In 1932, he finished his PhD and, with the help of a grant from the Rockefeller Foundation
Rockefeller Foundation
The Rockefeller Foundation is a prominent philanthropic organization and private foundation based at 420 Fifth Avenue, New York City. The preeminent institution established by the six-generation Rockefeller family, it was founded by John D. Rockefeller , along with his son John D. Rockefeller, Jr...

, moved to the Kaiser Wilhelm Institute for Medical Research
Max Planck Institute for Medical Research
The Max Planck Institute for Medical Research in Heidelberg, Germany, is a facility of the Max Planck Society for basic medical research. Since its foundation, six Nobel Prize laureates worked at the Institute: Otto Fritz Meyerhof , Richard Kuhn , Walther Bothe , André Michel Lwoff , Rudolf...

 of Heidelberg
Heidelberg
-Early history:Between 600,000 and 200,000 years ago, "Heidelberg Man" died at nearby Mauer. His jaw bone was discovered in 1907; with scientific dating, his remains were determined to be the earliest evidence of human life in Europe. In the 5th century BC, a Celtic fortress of refuge and place of...

 to Otto Meyerhof, where he did research on the development of flagellate
Flagellate
Flagellates are organisms with one or more whip-like organelles called flagella. Some cells in animals may be flagellate, for instance the spermatozoa of most phyla. Flowering plants do not produce flagellate cells, but ferns, mosses, green algae, some gymnosperms and other closely related plants...

s. Another Rockefeller grant allowed him go to Cambridge
University of Cambridge
The University of Cambridge is a public research university located in Cambridge, United Kingdom. It is the second-oldest university in both the United Kingdom and the English-speaking world , and the seventh-oldest globally...

 in 1937. In 1938, he was appointed departmental head at the Institut Pasteur, where he did groundbreaking research on bacteriophage
Bacteriophage
A bacteriophage is any one of a number of viruses that infect bacteria. They do this by injecting genetic material, which they carry enclosed in an outer protein capsid...

s and on the poliovirus
Poliovirus
Poliovirus, the causative agent of poliomyelitis, is a human enterovirus and member of the family of Picornaviridae.Poliovirus is composed of an RNA genome and a protein capsid. The genome is a single-stranded positive-sense RNA genome that is about 7500 nucleotides long. The viral particle is...

.

He has been awarded numerous prized from the French Académie des Sciences, the Grand Prix Charles-Leopold Mayer, the Leeuwenhoek Medal
Leeuwenhoek Medal
The Leeuwenhoek Medal, established in 1877 by the Royal Netherlands Academy of Arts and Sciences, , in honor of the 17th- and 18th-century microscopist Antoni van Leeuwenhoek, is granted every ten years to the scientist judged to have made the most significant contribution to microbiology during...

 of the Royal Netherlands Academy of Arts and Sciences
Royal Netherlands Academy of Arts and Sciences
The Royal Netherlands Academy of Arts and Sciences is an organisation dedicated to the advancement of science and literature in the Netherlands...

 in 1960 and the Keilin
David Keilin
David Keilin FRS was an entomologist, among other things.His family returned to Warsaw early in his youth. He did not attend school until age ten due to ill health and asthma. Only seven years later, in 1904, he enrolled in the University of Liège...

 Medal of the British Biochemical Society in 1964. He was awarded a Nobel Prize in Medicine
Nobel Prize in Physiology or Medicine
The Nobel Prize in Physiology or Medicine administered by the Nobel Foundation, is awarded once a year for outstanding discoveries in the field of life science and medicine. It is one of five Nobel Prizes established in 1895 by Swedish chemist Alfred Nobel, the inventor of dynamite, in his will...

 in 1965 for the discovery of the mechanism that some viruses (which he named provirus
Provirus
A provirus is a virus genome that is integrated into the DNA of a host cell.This state can be a stage of virus replication, or a state that persists over longer periods of time as either inactive viral infections or an endogenous retrovirus. In inactive viral infections the virus will not replicate...

es) use to infect bacteria.
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