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Ancient Iranian Medicine



 
 
The practice and study of medicine
Medicine

Medicine is the art and science of healing. It encompasses a range of health care practices evolved to maintain and restore health by the prevention and treatment of illness....
 in Persia has a long and prolific history. The Iranian academic centers like Jundishapur University (3rd century AD) were a breeding ground for the union among great scientists from different civilizations. These centers successfully followed their predecessors’ theories and greatly extended their scientific research through history.

In recent years, some experimental studies have indeed evaluated Medieval Iranian medical remedies using modern scientific methods.






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Faravahar
The practice and study of medicine
Medicine

Medicine is the art and science of healing. It encompasses a range of health care practices evolved to maintain and restore health by the prevention and treatment of illness....
 in Persia has a long and prolific history. The Iranian academic centers like Jundishapur University (3rd century AD) were a breeding ground for the union among great scientists from different civilizations. These centers successfully followed their predecessors’ theories and greatly extended their scientific research through history.

In recent years, some experimental studies have indeed evaluated Medieval Iranian medical remedies using modern scientific methods. These studies raised the possibility of revival of traditional treatments on the basis of evidence-based medicine.

History and background


Pre-Islamic

The medical history of ancient Persia can be divided into three distinct periods. The sixth book of Zend-Avesta
Avesta

The Avesta is the primary collection of sacred texts of Zoroastrianism, composed in the Avestan language....
 contains some of the earliest records of history of ancient Iranian medicine. The Vendidad
Vendidad

The Vendidad or Videvdat is a collection of texts within the greater compendium of the Avesta. However, unlike the other texts of the Avesta, the Vendidad is an ecclesiastical code, not a liturgical manual....
 in fact devotes most of the last chapters to medicine.

In a passage of the Vendidad
Vendidad

The Vendidad or Videvdat is a collection of texts within the greater compendium of the Avesta. However, unlike the other texts of the Avesta, the Vendidad is an ecclesiastical code, not a liturgical manual....
, one of the surviving texts of the Zandavesta, three kinds of medicine were distinguished: medicine by the knife (surgery), medicine by herbs, and medicine by divine words; and the best medicine was, according to the Vendidad, healing by divine words:

"Of all the healers O Spitama Zarathustra, namely those who heal with the knife, with herbs, and with sacred incantations, the last one is the most potent as he heals from the very source of diseases." (Ardibesht Yasht)


Although the Avesta mentions several notable physicians, the most notable of Persia's ancient physicians were to emerge later on, namely: Mani
Mani

Mani is a name or word occuring in several ethymologically-unrelated languagues and cultures, including:* Mani , a third-century founder of Manichaeism....
, Roozbeh, and Bozorgmehr.

The second epoch covers the era of what is known as Pahlavi literature, where the entire subject of medicine was systematically treated in an interesting tractate incorporated in the encyclopedic work of Dinkart, which listed in altered form some 4333 diseases.

The third era begins with the Achaemenid dynasty, and covers the period of Darius I, whose interest in medicine was said to be so great that he re-established the school of medicine in Sais, Egypt, which previously had been destroyed, restoring its books and equipment.

The first teaching hospital where medical students methodically practiced on patients under the supervision of physicians was the Academy of Gundishapur
Academy of Gundishapur

The Academy of Gundishapur was a renowned academy of learning in the city of Gundeshapur during late antiquity, the intellectual center of the Sassanid empire....
 in the Persian Empire
Persian Empire

The 'Persian Empire' was a series of successive Iranian or Persianization empires that ruled over the Iranian plateau, the original Persian homeland, and beyond in Southwest Asia, South Asia, Central Asia and the Caucasus....
. Some experts go so far as to claim that: "to a very large extent, the credit for the whole hospital system must be given to Persia".

According to the Vendidad
Vendidad

The Vendidad or Videvdat is a collection of texts within the greater compendium of the Avesta. However, unlike the other texts of the Avesta, the Vendidad is an ecclesiastical code, not a liturgical manual....
 physicians for the proof of proficiency had to cure three patients from the followers of Divyasnan and if they failed they could not practice medicine. At the first glance this recommendation may appear discriminative and based on human experimentation. But some authors have construed that from the beginning physicians were taught to remove the mental barrier and treat adversaries as well as friends . Interestingly, physician’s fee for service was based on the patient’s income.

Canons of Medicine
The Iranian science was interrupted by the Arab invasion
Islamic conquest of Persia

The Islamic conquest of Persian Empire led to the end of the Sassanid Persian Empire and the eventual extirpation of the Zoroastrianism religion in Iran....
 (630 A.D.). Many schools, universities and libraries were destroyed, books were burned and scholars killed. Nevertheless, the Iranian scientists carried on and the science of Persia resurfaced during the Islamic period. To save the books from the Arab carnage, many Pahlavi writings were translated into the Arabic, and Iran produced physicians and scientists as Avicenna, Razi and mathematicians as Kharazmi and Khayyam. They collected and systematically expanded the Greek, Indian, and Persian ancient medical heritage and made further discoveries.

After Islam


One of the main roles played by medieval Iranian scholars in the scientific field was the conservation, consolidation, coordination and development of ideas and knowledge in ancient civilizations. Some Iranian Hakim (practitioners) such as Muhammad ibn Zakariya ar-Razi, known to the West as Rhazes, and Ibn Sina
Avicenna

, known as Abu Ali Sina Balkhi or Ibn Sina and commonly known in English by his Latinized name Avicenna , was a Persian people polymath and the foremost Islamic medicine and Early Islamic philosophy of his time....
, better known as Avicenna, were not only responsible for accumulating all the existing information on medicine of the time, but adding to this knowledge by their own astute observations, experimentation and skills . "Qanoon fel teb of Avicenna" ("The Canon") and "Kitab al-hawi of Razi" ("Continens") were among the central texts in Western medical education from the 13th to the 18th centuries.

Persian physicians developed the first scientific method
Scientific method

Scientific method refers to techniques for investigating phenomenon, acquiring new knowledge, or correcting and integrating previous knowledge. To be termed scientific, a method of inquiry must be based on gathering observable, empirical and Measure evidence subject to specific principles of reasoning....
s for the field of medicine. This included the introduction of experimentation, quantification
Quantification

Quantification has two distinct meanings. In mathematics and empirical science, it refers to human acts, known as counting and measuring that map human sense observations and experiences into element s of some Set of numbers....
, clinical trial
Clinical trial

In health care, clinical trials are conducted to allow safety and efficacy data to be collected for new drugs or devices. These trials can only take place once satisfactory information has been gathered on the quality of the product and its non-clinical safety, and Institutional review board approval is granted in the country where the trial...
s, dissection
Dissection

Dissection is usually the process of disassembling and observing something to determine its internal structure and as an aid to discerning the function and relationships of its components....
, animal testing
Animal testing

Animal testing / animal experimentation is the use of non-human animals in Experiment. It is estimated that 50 to 100 million vertebrate animals worldwide — from zebrafish to non-human primates — are used annually....
, human experimentation
Human experimentation

Human subject research , or human subject use involves the use of human beings as research subjects. It is an important part of medical research, and many people volunteer for clinical trials of medical treatments....
 and postmortem autopsy
Autopsy

An autopsy, also known as a post-mortem examination, necropsy , autopsia cadaverum, or obduction, is a medical procedure that consists of a thorough examination of a Dead body to determine the cause and manner of death and to evaluate any disease or injury that may be present....
 by Muslim physicians, whilst hospitals in the Islamic world featured the first drug test
Drug test

A drug test is commonly a technical examination of urine, hair, blood, semen, sweat, or oral fluid samples to determine the presence or absence of specified drugs or their metabolized traces....
s, drug
Drug

A drug, broadly speaking, is any chemical substance that, when absorbed into the body of a living organism, alters normal bodily function....
 purity regulations, and competency tests
Test (student assessment)

A test or an examination is an assessment, often administered on paper or on the Computer-adaptive testing, intended to measure the test-takers' or respondents' knowledge, skills, aptitudes, or classification in many other topics ....
 for doctors.

In the 10th century, Muhammad ibn Zakariya ar-Razi (Rhazes) was the first to introduce controlled experiment
Scientific control

Scientific controls are a vital part of the scientific method, since they can eliminate or minimise unintended influences such as researcher bias, environmental changes and biological variation....
 and clinical
Clinical

Clinical can refer to:...
 observation
Observation

Observation is either an activity of a living being , consisting of receiving knowledge of the outside world through the senses, or the recording of data using scientific instruments....
 into the field of medicine, and the first to reject medical theories unverified by experiment
Experiment

In scientific inquiry, an experiment is a method of investigating causal relationships among variables. An experiment is a cornerstone of the empiricism approach to acquiring data about the world and is used in both natural sciences and social sciences....
ation. The first known medical experiment was carried out by Razi in order to find the most hygienic place to build a hospital. He hung pieces of meat in places throughout 10th century Baghdad
Baghdad

Baghdad is the Capital of Iraq and of Baghdad Governorate, with which it is also coterminous. With a municipal population estimated at 6.5 million, it is the largest city in Iraq, and the second largest city in the Arab World....
 and observed where the meat decomposed least quickly, and that was where he built the hospital. In his Comprehensive Book of Medicine, Razi recorded clinical
Clinical

Clinical can refer to:...
 cases of his own experience and provided very useful recordings of various disease
Disease

A disease or medical condition is an abnormal condition of an organism that impairs bodily functions, associated with specific symptoms and Medical signs....
s. In his Doubts about Galen, Razi was also the first to prove both Galen
Galen

Aelius Galenus or Claudius Galenus , better known as Galen of Pergamum , was a prominent Ancient Rome physician and philosopher of Greek origin, and probably the most accomplished medical researcher of the Roman period....
's theory of humorism
Humorism

Humourism, or humouralism, was a theory of the makeup and workings of the human body adopted by Ancient Greek medicine and Medicine in ancient Rome and Greek philosophy....
 and Aristotle
Aristotle

Aristotle was a Greeks philosopher, a student of Plato and teacher of Alexander the Great. He wrote on many subjects, including physics, metaphysics, Poetics , theater, music, logic, rhetoric, politics, government, ethics, biology and zoology....
's theory of classical element
Classical element

Many ancient philosophy used a set of archetype classical elements to explain patterns in nature. In this context, the word element refers to a chemical substance that is either a chemical compound or a mixture of chemical compounds , rather than a chemical element of modern physical science....
s false using an experimental method. He also introduced urinalysis
Urinalysis

File:Pyuria2.JPGA urinalysis is an array of tests performed on urine and one of the most common methods of medical diagnosis. A part of a urinalysis can be performed by using urine dipsticks, in which the test results can be read as color changes....
 and stool test
Stool test

File:Stool transport.JPGA stool test is one where fecal matter is collected for analysis to diagnose the presence or absence of a medical condition....
s.

Ibn Sina
Avicenna

, known as Abu Ali Sina Balkhi or Ibn Sina and commonly known in English by his Latinized name Avicenna , was a Persian people polymath and the foremost Islamic medicine and Early Islamic philosophy of his time....
 (Avicenna) is considered the father of modern medicine
Medicine

Medicine is the art and science of healing. It encompasses a range of health care practices evolved to maintain and restore health by the prevention and treatment of illness....
, for his introduction of systematic experiment
Experiment

In scientific inquiry, an experiment is a method of investigating causal relationships among variables. An experiment is a cornerstone of the empiricism approach to acquiring data about the world and is used in both natural sciences and social sciences....
ation and quantification
Quantification

Quantification has two distinct meanings. In mathematics and empirical science, it refers to human acts, known as counting and measuring that map human sense observations and experiences into element s of some Set of numbers....
 into the study of physiology
Physiology

Physiology is the study of the mechanical, physical, and biochemical functions of living organisms. Physiology has traditionally been divided between plant physiology and animal and all living things physiology but the principles of physiology are universal, no matter what particular organism is being studied....
, the introduction of clinical trial
Clinical trial

In health care, clinical trials are conducted to allow safety and efficacy data to be collected for new drugs or devices. These trials can only take place once satisfactory information has been gathered on the quality of the product and its non-clinical safety, and Institutional review board approval is granted in the country where the trial...
s, the experimental use and testing of drugs
Drug test

A drug test is commonly a technical examination of urine, hair, blood, semen, sweat, or oral fluid samples to determine the presence or absence of specified drugs or their metabolized traces....
, and a precise guide for practical experimentation in the process of discovering and proving the effectiveness of medical substances
Chemical substance

A chemical substance is a material with a specific Empirical formula. It is a concept that became firmly established in the late eighteenth century after work by the chemist Joseph Proust on the composition of some pure chemical compounds such as basic copper carbonate....
, in his medical encyclopedia, The Canon of Medicine
The Canon of Medicine

The Canon of Medicine is a 14-volume Islamic medicine written by a Science in medieval Islam and physician Avicenna and completed in 1025....
 (c. 1025).

Ibn Sina also discovered the contagious nature of infectious disease
Infectious disease

An infectious disease is a clinically evident disease resulting from the presence of pathogenic microbial agents, including pathogenic viruses, pathogenic bacteria, Mycosis, protozoa, multicellular parasites, and aberrant proteins known as prions....
s; introduced quarantine
Quarantine

Quarantine is voluntary or compulsory isolation, typically to contain the spread of something considered dangerous, often but not always disease....
 to limit the spread of contagious diseases; introduced experimental medicine, evidence-based medicine
Evidence-based medicine

Evidence-based medicine aims to apply evidence gained from the scientific method to certain parts of medical practice. It seeks to assess the quality of evidence relevant to the risks and benefits of therapy ....
, clinical trial
Clinical trial

In health care, clinical trials are conducted to allow safety and efficacy data to be collected for new drugs or devices. These trials can only take place once satisfactory information has been gathered on the quality of the product and its non-clinical safety, and Institutional review board approval is granted in the country where the trial...
s, randomized controlled trial
Randomized controlled trial

A randomized controlled trial is a type of scientific experiment most commonly used in testing the efficacy or effectiveness of healthcare Service or health technologies ....
s, efficacy
Efficacy

Efficacy is the capacity to produce an effect.It is these conditions that distinguish efficacy from the related concept of effectiveness, which relates to change under real-life conditions....
 tests, and clinical pharmacology
Clinical pharmacology

Clinical pharmacology is the science of medications and their clinical use. It is underpinned by the basic science of pharmacology, with added focus on the application of pharmacological principles and methods in the real world....
; recognized the importance of dietetics and the influence of climate and environment on health; distinguished mediastinitis
Mediastinitis

Mediastinitis is inflammation of the tissues in the mid-chest, or mediastinum. It can be either Acute or Chronic .Acute mediastinitis is usually bacterial and due to rupture of organs in the mediastinum....
 from pleurisy
Pleurisy

Pleurisy, also known as pleuritis, is an inflammation of the pleura, the lining of the pleural cavity surrounding the lungs. Among other things, infections are the most common cause of pleurisy....
; discovered the contagious nature of phthisis and tuberculosis
Tuberculosis

Tuberculosis is a common and often deadly infectious disease caused by mycobacterium, mainly Mycobacterium tuberculosis . Tuberculosis usually attacks the lungs but can also affect the central nervous system, the lymphatic system, the circulatory system, the genitourinary system, the gastrointestinal system, bones, joints, and even the...
, and the distribution of disease
Disease

A disease or medical condition is an abnormal condition of an organism that impairs bodily functions, associated with specific symptoms and Medical signs....
s by water
Water

Water is a common chemical substance that is essential for the survival of all known forms of life. In typical usage, water refers only to its liquid form or States of matter, but the substance also has a solid state, ice, and a gaseous state, water vapor or steam....
 and soil
Soil

Soil is the naturally occurring, unconsolidated or loose covering on the Earth's surface. Soil is composed of particles of broken rock that have been altered by chemical and environmental processes including weathering and erosion....
; provided the first careful descriptions of skin
Skin

The skin is the outer covering of the body, also known as the epidermis. It is the largest organ of the integumentary system made up of multiple layers of epithelial biological tissue, and guards the underlying muscles, bones, ligaments and organ s....
 troubles, sexually transmitted disease
Sexually transmitted disease

A sexually transmitted disease , also known as sexually transmitted infection or venereal disease , is an illness that has a significant probability of transmission between humans or animals by means of sexual contact, including sexual intercourse, oral sex, and anal sex....
s, perversion
Perversion

Perversion is a concept describing those types of human behavior that are perceived to be a serious deviation from what is considered to be orthodoxy or normal ....
s, and nervous
Nervous system

The nervous system is a Neural network of specialized cells that communicate information about an animal's surroundings and itself. It processes this information and causes reactions in other parts of the body....
 ailments, as well the use of ice
Ice

Ice is a solid phases of matter, usually crystalline solid, of a non-metallic substance that is liquid or gas at room temperature, such as ammonia ice or methane ice....
 to treat fever
Fever

Fever is a frequent medical sign that describes an increase in internal body temperature to levels above normal. Fever is most accurately characterized as a temporary elevation in the body's thermoregulatory set-point, usually by about 1?2 ?C ....
s; and separated medicine from pharmacology
Pharmacology

Pharmacology is the study of drug action. More specifically it is the study of the interactions that occur between a living organism and exogenous chemicals that alter normal biochemical function....
, which was important to the development of the pharmaceutical sciences
Pharmaceutical sciences

The pharmaceutical sciences are a group of interdisciplinary areas of study involved with the design, action, delivery, disposition, and use of drugs....
.

In the 14th century, the Persian language
Persian language

name=Persian|nativename=|pronunciation=[f??r'si]|image=|caption=Farsi in Perso-Arabic script |states= Iran, Afghanistan, Tajikistan, Uzbekistan, and Bahrain....
 medical work Tashrih al-badan (Anatomy of the body), by Mansur ibn Ilyas (c. 1390), contained comprehensive diagrams of the body's structural, nervous
Nervous system

The nervous system is a Neural network of specialized cells that communicate information about an animal's surroundings and itself. It processes this information and causes reactions in other parts of the body....
 and circulatory system
Circulatory system

The circulatory system is an organ that moves nutrients, gases, and wastes to and from cells to help fight diseases and help stabilize body temperature and pH to maintain homeostasis....
s.

Neurology and Neurosurgery


Evidence of surgery dates to the 3rd century BC, when the first cranial surgery was performed in the Shahr-e-Sukhteh (Burnt City) in south-eastern Iran. The archaeological studies on the skull of a 13-year-old girl suffering from hydrocephaly indicated that she had undergone cranial surgery to take a part of her skull bone and the girl lived for at least about 6 months after the surgery.

Several documents still exist from which the definitions and treatments of the headache
Headache

In medicine a headache or wiktionary:cephalalgia is a symptom of a number of different conditions of the head and sometimes neck. Some of the causes are benign while others are medical emergencies....
 in medieval Persia can be ascertained. These documents give detailed and precise clinical information on the different types of headaches. The medieval physicians listed various signs and symptoms, apparent causes, and hygienic and dietary rules for prevention of headaches. The medieval writings are both accurate and vivid, and they provide long lists of substances used in the treatment of headaches. Many of the approaches of physicians in medieval Persia are accepted today; however, still more of them could be of use to modern medicine.

Antiepileptic drug therapy plan in Medieval Iranian medicine is individualized, given different single and combined drug-therapy with a dosing schedule for each of those. Physicians stress the importance of dose, and route of administration and define a schedule for drug administration. Recent animal experiments confirm the anticonvulsant potency of some of the compounds which are recommended by Medieval Iranian practitioners in epilepsy treatment.

Avicenna
Avicenna

, known as Abu Ali Sina Balkhi or Ibn Sina and commonly known in English by his Latinized name Avicenna , was a Persian people polymath and the foremost Islamic medicine and Early Islamic philosophy of his time....
 (Ibn Sina) was a pioneer in neuropsychiatry
Neuropsychiatry

Neuropsychiatry is the branch of medicine dealing with mental disorders attributable to diseases of the nervous system.It preceded the current disciplines of psychiatry and neurology, in as much as psychiatrists and neurologists had a common training ....
. In The Canon of Medicine
The Canon of Medicine

The Canon of Medicine is a 14-volume Islamic medicine written by a Science in medieval Islam and physician Avicenna and completed in 1025....
 (c. 1025), he first described numerous neuropsychiatric conditions, including hallucination
Hallucination

A hallucination, in the broadest sense, is a perception in the absence of a stimulus . In a stricter sense, hallucinations are defined as perceptions in a conscious and awake state in the absence of external stimuli which have qualities of real perception, in that they are vivid, substantial, and located in external objective space....
, insomnia
Insomnia

Insomnia is a symptom of a sleep disorder characterized by persistent difficulty falling sleep or staying asleep despite the opportunity. Insomnia is a symptom, not a stand-alone diagnosis or a disease....
, mania
Mania

Mania is a severe medical condition characterized by extremely elevated mood, energy, unusual thought patterns and sometimes psychosis. There are several possible causes for mania including drug abuse and brain tumours, but it is most often associated with bipolar disorder, where episodes of mania may cyclically alternate with episodes of ma...
, nightmare
Nightmare

A nightmare is a dream which causes a strong unpleasant emotional response from the sleeper, typically fear or horror, being in situations of extreme danger, or the sensations of pain, bad events, falling, drowning or death....
, melancholia
Melancholia

Melancholia , in contemporary usage, is a mood disorder of non-specific depression , characterized by low levels of enthusiasm and eagerness for activity....
, dementia
Dementia

Dementia is the progressive decline in cognition due to damage or disease in the body beyond what might be expected from normal aging. Although dementia is far more common in the geriatric population, it may occur in any stage of adulthood....
, epilepsy
Epilepsy

Epilepsy is a common chronic neurological disorder characterized by recurrent unprovoked seizure s. These seizures are transient signs and/or symptoms of abnormal, excessive or synchronous neuronal activity in the brain....
, paralysis
Paralysis

Paralysis is the complete loss of muscle function for one or more muscle groups. Paralysis can cause loss of feeling or loss of mobility in the affected area....
, stroke
Stroke

A stroke is the rapidly developing loss of brain function due to a disturbance in the blood supply to the brain. According to the National Stroke Association, a "stroke" occurs when a blood clot blocks and artery or a blood vessel breaks, interrupting blood flow to an area of the brain....
, vertigo
Vertigo (medical)

Vertigo is a specific type of dizziness, a major symptom of a balance disorder. It is the sensation of spinning or swaying while the body is actually stationary with respect to the surroundings....
 and tremor
Tremor

Tremor is an unintentional, somewhat rhythmic, muscle movement involving to-and-fro movements of one or more body parts. It is the most common of all involuntary movements and can affect the hands, arms, head, face, vocal cords, trunk, and legs....
.

Obstetrics and Gynecology


In the 10th century work of Shahnama
Shahnameh

File:Ferdowsi tehran.jpg Shahnam?, or Shahnama , "The Great Book" , is an enormous poetic opus written by the Persian literature Ferdowsi around 1000 AD and is the national epic of Iran....
, Ferdowsi
Ferdowsi

Hakim Abu'l-Qasim Firdawsi Tusi , more commonly transliterated as Ferdowsi , was a highly revered Persian people poet. He was the author of the Shahnameh, the national epic of Iran as well as other Persian communities in other countries....
 describes a Caesarean section
Caesarean section

File:Cesarian the moment of birth3.jpgA Caesarean section , also known as C-section or Caesar, is a surgery procedure in which incisions are made through a mother's abdomen and uterus to deliver one or more infant....
 performed on Rudaba
Rudaba

Rudaba or Roodabeh is a Persian people mythological female figure in Ferdowsi's epic Shahnameh. She is the princess of Kabul, daughter of Mehrab Kaboli, and later she becomes the first of Zal's wives....
, during which a special wine
Wine

Wine is an alcoholic beverage often made of fermentation grape juice. The natural chemical balance of grapes is such that they can ferment without the addition of sugars, acids, enzymes or other nutrients....
 agent was prepared by a Zoroastrian
Zoroastrianism

Zoroastrianism is the religion and philosophy based on the teachings ascribed to the prophet Zoroaster, after whom the religion is named. The term Zoroastrianism is in general usage, essentially synonymous with Mazdaism, i.e., the worship of Ahura Mazda, exalted by Zoroaster as the supreme divine authority....
 priest and used as an anesthetic to produce unconsciousness for the operation. Although largely mythical in content, the passage illustrates working knowledge of anesthesia
Anesthesia

Anesthesia, or anaesthesia , has traditionally meant the condition of having sensation blocked or temporarily taken away. This allows patients to undergo surgery and other procedures without the distress and pain they would otherwise experience....
 in ancient Persia.

See also

  • Science in Iran
  • Islamic medicine
    Islamic medicine

    In the history of medicine, Islamic medicine or Arabic medicine refers to medicine developed in the Islamic Golden Age and written in Arabic language, the lingua franca of the Islamic civilization....


External links